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Supersmile Medical Research Studies

Up-to-date List of Supersmile Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Supersmile Medical Research Studies

Rank Status Study
1 Recruiting Firefly ANKLE Sprain Study
Condition: Grade I/II Ankle Sprain
Interventions: Device: firefly;   Other: Standard of care
Outcome Measures: Oedema lower leg;   FAAM ankle function measure;   Ankle proprioception - as assessed by the time that the participant can stand on one leg for with their eyes closed, this will be recorded and repeated three times, the average will be taken;   VAS Pain score;   Adverse event rate
2 Recruiting Fluorescence Imaging + ICG Dye for Use in the Visual Diagnosis of Endometriosis
Condition: Endometriosis
Intervention: Other: Participants will receive ICG Dye
Outcome Measures: Quality of fluorescence imaging using + ICG dye (Firefly).;   Quality of Life
3 Recruiting Detection of SLN in Patients With Endometrial Cancer Undergoing Robotic Assisted Staging: Comparison of ISB and ICG
Condition: Endometrial Cancer
Interventions: Device: ISB dye and standard white light imaging;   Device: ICG dye and FireFly fluorescence imaging
Outcome Measures: Number of pelvic sentinel lymph nodes (SLN) in endometrial cancer patients detected by either ICG and/or ISB dyes.;   Negative predictive value (NPV) of pelvic SLN in endometrial cancer in relation to the number of nodes with metastasis.
4 Not yet recruiting Efficacy of a Mobile Application in the Smoking Cessation Among Young People
Condition: Smoking Cessation
Interventions: Other: Control group;   Device: Cell phone Aplication for Smarth Phone
Outcome Measure: Smoking cessation
5 Recruiting Antimicrobial Agent for Reducing Bacteria in Aerosols and Oral Cavity
Condition: Dental Prophylaxis and Implant Surgery
Interventions: Drug: 0.2% w/v Chlorhexidine digluconate;   Drug: Sodium fluoride toothpaste (Aquafresh Mild & Minty)
Outcome Measures: Total number of detectable plaque bacteria sampled post implant surgery;   Total number of detectable plaque bacteria sampled at day 1 and day 7;   Total number of detectable plaque bacteria sampled recoverable viable bacteria in an aerosol generated during a typical dental procedure (dental prophylaxis);   Area under the curve (AUC) for the total number of plaque bacteria in the mouth post implant surgery
6 Recruiting Development of a MR Scanner Capable of Being Sited in a Neonatal Intensive Care Unit
Condition: Image Evaluation
Intervention: Device: Neonatal MRI Scanner
Outcome Measures: Neonate MR scanner feasibility;   Neonate MR scanner image quality;   MR neonate usability Information
7 Recruiting Intraoperative Folate-fluorescein Conjugate (EC17) Lung Cancer (CA)
Conditions: Lung and Pleural Malignancies;   Neoplasms;   Nodules
Intervention: Drug: EC17
Outcome Measures: The ability of EC17 and the imaging system to detect FRA positive tumors during surgery conducted 2-4 hours post EC-17 administration.;   The number of participants that will have an adverse reaction to the EC17
8 Recruiting Intraoperative Imagery of Renal Nodules With Folate-fluorescein Conjugate(EC17)
Condition: Renal Cell Carcinoma
Intervention: Drug: EC17
Outcome Measures: The ability of EC17 and the imaging system to detect FRA positive tumors during surgery conducted 2-4 hours post EC-17 administration.;   The number of participants that will have an adverse reaction to the EC17
9 Recruiting EC17 for Intraoperative Imaging for Parathyroidectomy
Condition: Primary Hyperparathyroidism
Intervention: Drug: EC17
Outcome Measures: The ability of EC17 and the imaging system to detect FRA positive tumors during surgery conducted 2-4 hours post EC-17 administration.;   The number of participants that will have an adverse reaction to EC17
10 Not yet recruiting Radiographic Contrast To Differentiate Cavitated From Non-cavitated Tooth Decay
Condition: Dental Caries
Intervention: Device: Sodium iodide
Outcome Measure: Number of cavitated versus non-cavitated caries lesions in 116 tooth surfaces.

These studies may lead to new treatments and are adding insight into Supersmile etiology and treatment.

A major focus of Supersmile research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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