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Systane Medical Research Studies

Up-to-date List of Systane Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Systane Medical Research Studies

Rank Status Study
1 Unknown  Patient Satisfaction and Tear Osmolarity With the Use of Blink Tears, Blink Gel Tears and Systane Balance
Condition: Dry Eye
Interventions: Other: Blink Tears lubricating Eye Drops;   Other: Blink Gel Tears Lubricating Eye Drops;   Other: Systane Balance Lubricant Eye Drop
Outcome Measures: Primary efficacy variable is tear osmolarity;   Secondary efficacy variable is the Patient Symptom Questionnaire
2 Recruiting Efficacy and Safety of PRO-148 Versus Systane®, in Patients With Mild to Moderate Dry Eye
Condition: Dry Eye
Interventions: Drug: PRO-148;   Drug: Systane
Outcome Measures: Tear film break up time;   Ocular Surface Disease Index;   Schirmer test
3 Unknown  Efficacy of FreshKote and Systane for the Treatment of Dry Eye and Improvement of Osmolarity
Condition: Dry Eye
Interventions: Drug: FreshKote;   Drug: Systane
Outcome Measures: TBUT;   Best Corrected Visual Acuity
4 Recruiting Clinical Outcomes Following Treatment With Systane® Balance in Dry Eye Subjects
Condition: Dry Eye
Interventions: Drug: Propylene Glycol, 0.6% eye drops;   Drug: Preservative-free 0.9% Saline solution
Outcome Measures: Change from baseline in tear film break-up time (TFBUT) at Day 35;   Change from baseline in Total Ocular Surface Staining (TOSS) score at Day 35;   Change from baseline in ocular surface disease index (OSDI) score at Day 35;   Change from baseline in Impact of Dry Eye on Everyday Life (IDEEL) Treatment Effectiveness score at Day 35;   Change from baseline in IDEEL Treatment Inconvenience score at Day 35
5 Unknown  Tears Substitutions and Their Effects on Higher Order Aberrometery
Condition: Dry Eye Syndrome
Interventions: Other: Preservative Free Saline;   Other: Optive;   Other: Refresh Moderate/Severe;   Other: Systane;   Other: Systane Ultra
Outcome Measure: Measurement of a subject's higher order aberrations over time is the primary outcome measure
6 Unknown  Effect of Topical Nepafenac in Macular Thickening Related to Pan-Retinal Photocoagulation
Conditions: Macular Thickening;   Macular Edema
Interventions: Drug: Nepafenac;   Other: Lubricant
Outcome Measures: Central macular thickening;   Best corrected visual acuity
7 Recruiting Topic Antiinflammatory Therapy Added to Selective Photocoagulation in Macular Edema
Conditions: Diabetic Retinopathy;   Macular Edema
Interventions: Drug: Tromethamine ketorolac;   Drug: Nepafenac;   Drug: Polietilenglicol 400, propilenglicol, HP guar
Outcome Measures: ocular topic antiinflammatory therapy (ketorolac, nepafenac or placebo) applied 3 times a day in the treated eye for a week after selective photocoagulation;   center point thickness using stratus OCT measured in microns;   macular volume using stratus OCT measured in cubic millimeters;   visual capacity under subjective refractive correction measured in decimal equivalent
8 Unknown  Aqueous Humor Dynamics and Brimonidine
Condition: Intraocular Pressure
Interventions: Drug: Brimonidine;   Drug: Artificial tears
Outcome Measure: Aqueous Humor Dynamics

These studies may lead to new treatments and are adding insight into Systane etiology and treatment.

A major focus of Systane research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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