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Tachycardia Medical Research Studies

Up-to-date List of Tachycardia Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Tachycardia Medical Research Studies

Rank Status Study
1 Recruiting Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia
Conditions: AtrioVentricular Nodal Reentrant Tachycardia;   Supraventricular Tachycardia;   Heart Disease
Intervention: Device: Freezor Xtra Cryoablation Catheter
Outcome Measures: Number of Participants with Successful Procedures and No AtrioVentricular Nodal Reentrant Tachycardia Recurrence;   Number of Participants with Adverse Events as a Measure of Safety;   Number of Participants who had Acutely Successful Procedures and No Atrioventricular Nodal Reentrant Tachycardia Recurrence.
2 Recruiting Trial Comparing Ablation With Medical Therapy in Patients With Ventricular Tachycardia
Conditions: Ventricular Tachycardia;   Coronary Artery Disease
Interventions: Procedure: Catheter Ablation;   Drug: Medical therapy (sotalol or amiodarone)
Outcome Measures: Recurrence of Ventricular Tachycardia;   Time to First Shock/ATP for VT or to First Presentation of Sustained VT;   Total mortality;   Sudden cardiac death;   Syncope;   Number of hospitalizations;   QOL measures
3 Not yet recruiting Intramural Needle Ablation for Ablation of Recurrent Ventricular Tachycardia
Condition: Ventricular Tachycardia
Intervention: Device: Intramural Needle Ablation Catheter
Outcome Measures: Control of Ventricular Tachycardia (VT);   Absence of all serious adverse events;   Acute Procedural Success
4 Unknown  Anti-arrhythmic Medication v. MRI-Merge Ablation in the Treatment of Ventricular Tachycardia
Condition: Ventricular Tachycardia
Interventions: Procedure: MRI guided VT ablation;   Drug: Increased dose of amiodarone
Outcome Measures: Freedom from ventricular Tachycardia documented by implantable defibrillator cardioverter 6 months post ablation.;   inducible arrhythmia at the end of the procedure,;   Procedure time;   Comparison of endocardial voltage mapping to scar on delayed enhancement MRI images;   Complications of the procedure
5 Recruiting Feasibility of Contact Force Catheter Mapping and Ablation in Epicardial and Endocardial Ventricular Tachycardias
Conditions: Ventricular Tachycardia;   Sudden Death;   Syncope;   Chest Pain
Intervention: Procedure: Catheter ablation
Outcome Measures: Evaluate the feasibility of mapping and ablating ventricular Tachycardias in endocardial and epicardial using a contact force catheter;   Evaluate the impedance and voltage threshold for scar in chronic chagasic cardiomyopathy
6 Recruiting Cognitive Dysfunction in Postural Tachycardia Syndrome
Condition: Postural Tachycardia Syndrome
Interventions: Behavioral: Seated Measurements;   Behavioral: Standing Measurements;   Behavioral: Self-Administered Surveys
Outcome Measures: Standing Digits Backwards Test;   Cognitive Domain Score (CDS)
7 Unknown  Dexmedetomidine Versus Adenosine: Electrophysiologic Effects and Therapeutic Use for Terminating Supraventricular Tachycardia
Condition: Supraventricular Tachycardia
Interventions: Drug: Dexmedetomidine;   Drug: Adenosine
Outcome Measures: Termination of SVT;   Incidence and duration of sinus pause or asystole after termination of SVT;   Incidence of Tachyarrhythmias;   Hypotension and hypertension
8 Recruiting Ventricular Tachycardia (VT) Ablation Versus Enhanced Drug Therapy
Condition: Recurrent Ventricular Tachycardia
Interventions: Procedure: Catheter Ablation;   Drug: Aggressive Antiarrhythmic Therapy (Amiodarone)
Outcome Measures: Appropriate ICD shocks,VT storm and death;   All cause mortality
9 Recruiting Ablation of Inappropriate Sinus Tachycardia
Condition: Inappropriate Sinus Tachycardia
Intervention: Procedure: electrophysiology study and radiofrequency ablation
Outcome Measures: Improvement in:symptoms(palpitations);quality of life;resting heart rate;mean 24 hour heart rate;heart rate variability;;   duration of symptom limited Bruce protocol exercise treadmill test;duration of exercise test required to increase rate by 20%.
10 Unknown  Testing Objective Methods for Template Matching Ventricular Tachycardia and Pacemapping
Condition: Ventricular Tachycardia
Intervention:
Outcome Measure: Correlating the arithmetic markers (CORR and MAD) to the distance between the pacing site and origin of the ventricular Tachycardia or the index pacing site.
11 Recruiting Yoga and Rate and Duration of Inappropriate Sinus Tachycardia (IST) Episodes
Condition: Inappropriate Sinus Tachycardia
Intervention: Other: Yoga
Outcome Measures: Determine if Yoga affects the rate and duration of IST episodes;   Effect yoga has on resting heart rate or occurrence of IST episodes in patients that have undergone treatment with medications and/or ablation procedures;   Change in Quality of Life
12 Recruiting Aldosterone & Sodium Regulation in Postural Tachycardia Syndrome - Screening
Condition: Postural Tachycardia Syndrome
Interventions: Other: Autonomic Function Testing;   Other: Posture Study;   Procedure: Measurement of Total Blood Volume;   Other: Exercise Capacity Test
Outcome Measure: blood volume deviation (%) from individual predicted volumes
13 Unknown  Iv Amiodarone Versus Iv Procainamide to Treat Haemodynamically Well Tolerated Ventricular Tachycardia
Conditions: Ventricular Tachycardia;   Wide QRS Tachycardia
Intervention: Drug: iv Amiodarone and iv Procainamide
Outcome Measures: To compare clinically significant cardiac adverse events occurring within 40 minutes from treatment initiation;   To compare efficacy of both therapies in relation to episode termination;   To compare the rate of total adverse events, cardiac and non cardiac, occurring during an observation period of 24 hours after treatment was applied
14 Recruiting AV Nodal Reentrant Tachycardia Study
Condition: Tachycardia, Atrioventricular Nodal Reentry
Intervention: Procedure: Cardiac Invasive Electrophysiological Study
Outcome Measure: raise the frequency of success to more than 98%
15 Recruiting Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)
Conditions: Postural Tachycardia Syndrome;   Postural Orthostatic Tachycardia Syndrome
Interventions: Device: Inspiratory Threshold Device (Res-Q-Gard ITD);   Device: Sham Inspiratory Threshold Device
Outcome Measures: Magnitude of orthostatic heart rate increase on upright posture;   Symptoms rating with upright posture;   Hemodynamic changes on upright posture
16 Recruiting Dietary Salt in Postural Tachycardia Syndrome
Condition: Postural Orthostatic Tachycardia Syndrome
Interventions: Radiation: Blood Volume;   Radiation: Total Blood Volume;   Procedure: Exercise Capacity Test - Bicycle;   Procedure: Posture Study
Outcome Measures: blood volume;   Magnitude of suppression of aldosterone (from low sodium to high sodium diets) and a reduction in orthostatic Tachycardia and orthostatic symptoms in POTS patients with the high-sodium diet.
17 Not yet recruiting Fibrillatory Factor in Ventricular Tachycardia
Condition: Ventricular Tachycardia
Intervention: Procedure: Fibrillatory Factor calculation (FF)
Outcome Measures: Fibrillatory Factor;   Real-time fibrillatory factor
18 Recruiting Ultra-high Density Mapping With Multielectrode Catheter vs Conventional Point by Point Mapping for Ventricular Tachycardia Substrate Ablation
Condition: Ventricular Tachycardia
Interventions: Device: Ablation guided by conventional mapping.;   Device: Ablation guided by ultra-high density mapping with multielectrode catheter.
Outcome Measures: Mapping and ablation times;   Scar area correlation with MRI.;   Radiofrequency delivery time.;   Reduction of residual electrograms with delayed component.;   Ventricular Tachycardia inducibility after ablation.
19 Recruiting Ivabradine Versus Beta-blockers in the Treatment of Inappropriate Sinus Tachycardia
Condition: Inappropriate Sinus Tachycardia
Interventions: Drug: Ivabradine;   Drug: Beta blocker
Outcome Measures: heart rate reduction;   physical tolerance and quality of life
20 Not yet recruiting Substrate Targeted Ablation Using the Cool Flex™ Irrigated Catheter Ablation System for the Reduction of Ventricular Tachycardia
Condition: Monomorphic Ventricular Tachycardia
Intervention: Device: Cardiac catheter ablation with ICD
Outcome Measures: Number of ICD shocks including both appropriate and inappropriate shocks;   Number of cardio-vascular (CV) hospitalizations and CV-related ER visits

These studies may lead to new treatments and are adding insight into Tachycardia etiology and treatment.

A major focus of Tachycardia research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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