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Teduglutide Medical Research Studies

Up-to-date List of Teduglutide Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Teduglutide Medical Research Studies

Rank Status Study
1 Not yet recruiting A Study of the Gut Barrier and Blood Vessel Inflammation in Individuals With and Without HIV
Condition: HIV
Interventions: Drug: Teduglutide;   Drug: Placebo
Outcome Measures: Change in soluble CD14 concentration;   Change in intestinal epithelial integrity;   Change in arterial target to background ratio of 18-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) uptake;   Change in intestinal CD4+ T-cell percentage;   Change in plaque volume on cardiac computed tomography angiography;   Change in hemoglobin A1c percentage;   Change in Homeostatic Model Assessment-Insulin Resistance (HOMA-IR);   Change in visceral adipose tissue (VAT) area;   Change in subcutaneous adipose tissue (SAT) area;   Change in body mass index (BMI);   Change in soluble CD163 concentration;   Change in intestinal fatty acid binding protein concentration;   Change in bone mineral density;   Change in lipopolysaccharide (LPS) concentration
2 Recruiting A Prospective, Multi-center Registry for Patients With Short Bowel Syndrome
Condition: Short Bowel Syndrome
Intervention:
Outcome Measures: Occurrence of colorectal cancer in patients with short bowel syndrome who are treated with Teduglutide in a routine clinical setting;   Occurrence of other malignancy in patients with short bowel syndrome who are treated with Teduglutide in a routine clinical setting;   Actual volume change in parenteral support in patients with short bowel syndrome who are treated with Teduglutide in a routine clinical setting;   Occurrence of benign neoplasia of the gastrointestinal tract, hepatobiliary system, and pancreas in patients with short bowel syndrome who are treated with Teduglutide in a routine clinical setting;   Occurrence of colorectal polyps in patients with short bowel syndrome who are treated with Teduglutide in a routine clinical setting;   Occurrence of intestinal obstruction in patients with short bowel syndrome who are treated with Teduglutide in a routine clinical setting;   Occurrence of pancreatic and biliary disease in patients with short bowel syndrome who who are treated with Teduglutide in a routine clinical setting;   Occurrence of heart failure and other manifestations of volume overload in patients with short bowel syndrome who who are treated with Teduglutide in a routine clinical setting;   Occurrence of allergic/hypersensitivity reaction to Teduglutide in patients with short bowel syndrome who who are treated with Teduglutide in a routine clinical setting;   Percentage volume change in parenteral support in patients with short bowel syndrome who are treated with Teduglutide in a routine clinical setting;   Occurrence of other long-term safety outcomes in patients with short bowel syndrome who are treated with Teduglutide in a routine clinical setting
3 Recruiting Evaluate the Safety, Efficacy and Pharmacokinetics of Teduglutide in Japanese Subjects With PN-dependent Short Bowel Syndrome
Condition: Short Bowel Syndrome
Intervention: Drug: Teduglutide
Outcome Measures: Absolute and percent change from baseline in weekly PN/I.V;   Cmax (tmax)

These studies may lead to new treatments and are adding insight into Teduglutide etiology and treatment.

A major focus of Teduglutide research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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