Up-to-date List of Theraflu Medical Research Studies
What Research is Being Done?
A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.
Neuropsychological test (Mullen Scales of Early Learning).; Behavior scale: Vineland Adaptive Behavior Scales (VABS); Behavior and temperament dysregulation measured by the Ghuman-Folstein Screen for Social Interaction (SSI);.
Drug: Dextromethorphan (drug used like antitussive); Drug: Memantine (drug used in Alzheimer's disease); Drug: Placebo (lactose)
Measure of pain by numerical scale; Patient Global Impression if Change (PGIC); Leed's slip questionnaire; Questionnaire of quality of life SF 36; DN4 scale; Neuropathic Pain Symptoms Inventory (NPSI); Saint-Antoine questionnaire (QDSA); HAD scale; Questionnaire of identification of pain (QCD); Evaluation of cognitive impact (Cantab, Cambridge)
Unified Dyskinesia Rating Scale (UDysRS), part 3; UDysRS, part 4; Movement Disorder Society- Unified Parkinson's Disease Rating Scale (MDS-UPDRS), part III-motor score; Bradykinesia; MDS-UPDRS part I, II, and IV; UDysRS part 1 and 2; PD Motor Diary
Neuropsychiatric Inventory (NPI); Safety and Tolerability; ADCS-CGIC (Alzheimer's Disease Cooperative Study - Clinical Global Impression of Change Rating); QoL-AD (Quality of Life - Alzheimer's Disease measure); ADCS-ADL (Alzheimer's Disease Cooperative Study - Activities of Daily Living Inventory); CSI (Caregiver Strain Index)
Change in Montgomery-Asberg Depression Rating Scale; Change in Quality of Life Enjoyment and Satisfaction Questionnaire Short Form; Change in Range of Impaired Functioning Tool; Change in Sheehan Disability Scale; Patient Rated Inventory of Side Effects (PRISE); Columbia-Suicide Severity Rating Scale (C-SSRS); Quick Inventory of Depressive Symptomatology, Self Report (QIDS-SR); Clinical Global Impression (CGI) scale; Change in Massachusetts General Hospital Cognitive and Physical Functioning Questionnaire (CPFQ)
The primary efficacy endpoint is the mean change from baseline at 12 weeks in CNS-LS score.; Safety and Tolerability; PBA Episode Counts; Patient Global Impression-Change (PGI-C); Clinical Global Impression-Change (CGI-C); Patient Satisfaction with Treatment Survey
Rating of "Drug Liking" on the End of Day Questionnaire; Hallucinogen Rating Scale
These studies may lead to new treatments and are adding insight into Theraflu etiology and treatment.
A major focus of Theraflu research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.