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Tonsillectomy Medical Research Studies

Up-to-date List of Tonsillectomy Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Tonsillectomy Medical Research Studies

Rank Status Study
1 Unknown  Coblation-Tonsillotomy vs Electrocautery-Tonsillectomy for the Treatment of Obstructive Sleep Apnea (OSA) in Children
Condition: Obstructive Sleep Apnea
Interventions: Procedure: Electrocautery-Tonsillectomy;   Procedure: Coblation-tonsillotomy
Outcome Measures: Compare coblation-tonsillotomy to electrocautery-Tonsillectomy as a treatment of obstructive sleep apnea (OSA), as assessed by apnea-hypopnea index (AHI) measured on polysomnography (PSG);   Evaluate post-operative pain and analgesic use associated with electrocautery-Tonsillectomy and coblation-tonsillotomy;   Evaluate quality of life following coblation-tonsillotomy and electrocautery-Tonsillectomy for the treatment of OSA
2 Recruiting Safety Study of Post Tonsillectomy Ibuprofen Use in Adults
Conditions: Secondary Post Tonsillectomy Hemorrhage;   Primary Post Tonsillectomy Hemorrhage
Intervention: Drug: Ibuprofen
Outcome Measures: clinically defined tonsil bleed rate (percentage);   Hospital readmission rate (percentage);   Subclinical (not requiring intervention) subjectively reported tonsil bleed rate (percentage);   Pain scale rating;   Nausea Scale
3 Unknown  The Effects of Reducing Stomach Acid on Post-Tonsillectomy Pain
Conditions: Post-Tonsillectomy Pain;   Post-Tonsillectomy Activity;   Post-Tonsillectomy Hydration
Interventions: Drug: Lansoprazole;   Drug: Placebo
Outcome Measures: The primary outcome is the number of days to become free of narcotic pain medication.;   The secondary outcomes are the number of days to be free of pain, the number od days to return to normal activity levels and the number of days to return to normal fluid intake.
4 Unknown  Outcome of Laser or Debrider Tonsillotomy Versus Tonsillectomy in Obstructive Sleep Apnea
Condition: Obstructive Sleep Apnea
Intervention: Procedure: Tonsillectomy, laser tonsillotomy, debrider tonsillotomy
Outcome Measures: Difference between the three arms regarding serum IL1 beta, TNF alpha, IL2, IL6.;   Difference between the three arms regarding pain, post Tonsillectomy bleeding and post operative sleep disturbance.
5 Recruiting Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy
Conditions: Tonsillectomy;   Adenoidectomy
Interventions: Drug: Ibuprofen;   Drug: Acetaminophen
Outcome Measure: Level 3 postoperative hemorrhage
6 Not yet recruiting Pharmacogenomics Analysis of Morphine Pharmacokinetics in Pediatric Tonsillectomy and Adenoidectomy
Conditions: Tonsillectomy;   Adenoidectomy;   Pharmacokinetics
Intervention:
Outcome Measure: The primary endpoint will be to identify genetic variants that contribute to the variability of morphine analgesic response following pediatric day surgery T&A.
7 Unknown  Traumeel for Post-Tonsillectomy Pain
Condition: Post-Tonsillectomy
Interventions: Drug: Traumeel S;   Drug: TRAUMEEL S;   Drug: Placebo
Outcome Measures: postoperative pain, as registered on the NRS;   analgesic use (dipyrone);   post-operative bleeding (quantified on a scale of 1-4);   nocturnal awakenings;   time to resumption of eating and return to normal activity;   cytokine levels (CRP, IL-6) at 36 hours postoperative;   side effects of the treatment.
8 Unknown  Change of Nasalance After Tonsillectomy in Thai Adult
Conditions: Voice Quality;   Tonsillectomy
Intervention:
Outcome Measure:
9 Unknown  Acupuncture for Post-Tonsillectomy Pain Control in Children
Conditions: Tonsillectomy;   Post-Operative Pain;   Acupuncture
Intervention: Device: acupuncture
Outcome Measures: Post-Operative Pain;   Analgesic Drug Consumption
10 Recruiting Analgesic Effect of IV Acetaminophen in Tonsillectomies
Conditions: Adenotonsillitis;   Tonsillitis
Interventions: Drug: Acetaminophen (paracetamol);   Drug: Morphine (hydromorphone)
Outcome Measures: Analgesic efficacy of single dose intravenous acetaminophen in pediatric patients undergoing Tonsillectomy to measure opioid consumption and pain scores in the first 8-12 postoperative hours.;   To observe recovery characteristics in the PACU and floor in patients following Tonsillectomy.
11 Unknown  Risk Stratification of Post Tonsillectomy Respiratory Complications in the Pediatric Population
Condition: Post Tonsillectomy Respiratory Complications
Intervention:
Outcome Measure: respiratory distress
12 Recruiting Preoperative Gabapentin for Post-Tonsillectomy Pain in Children
Condition: Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
Interventions: Drug: Gabapentin;   Drug: liquid placebo
Outcome Measures: Total oral analgesia consumption;   Self-report pain score
13 Unknown  The Effect of Intravenous Lidocaine on Pain After Tonsillectomy
Condition: Postoperative Pain
Interventions: Drug: Intravenous lidocaine injection;   Drug: Intravenous normal saline injection
Outcome Measures: Visual analogue scale 4hour;   visual analogue scale 12 hour;   visual analogue scale 24hour;   Visual analogue scale 48hour;   Opioid consumption 4hour;   Opioid consumption 24hour;   Opioid consumption 12 hour;   Opioid consumption 48hour;   FPB 4 hour;   FPB 12 hour;   FPB 24 hour;   FPB 48 hour
14 Recruiting Auricular Acupuncture for The Treatment of Post-Tonsillectomy Pain
Conditions: Recurrent Tonsillitis;   Recurrent Peritonsillar Abscess;   Obstructive Sleep Apnea
Intervention: Procedure: Auricular Acupuncture
Outcome Measure: Reduction in VAS scores between experimental and control group
15 Recruiting The Effect of Peritonsillar Infiltration of Ketamine and Dexamethasone for Postoperative Pain Relief in Children Following AdenoTonsillectomy
Condition: Tonsillectomy
Interventions: Drug: saline;   Drug: Ketamine;   Drug: Dexamethasone;   Drug: ketamine-dexamethasone
Outcome Measures: pain will be assessed by [observational pain scores (OPS)];   time to first demand of analgesia;   postoperative analgesic consumption;   nausea, vomiting will be assessed by questioning their parents.;   bleeding will be assessed by questioning their parents;   family satisfaction will be assessed by questioning their parents.
16 Unknown  Evaluation of The Effect of Bupivacaine (Marcaine) in Reducing Early Post Tonsillectomy Pain
Condition: Tonsillectomy
Interventions: Drug: Bupivacaine;   Drug: normal saline
Outcome Measure:
17 Unknown  Etoricoxib in Ear Nose Throat Surgery
Condition: Tonsillectomy
Interventions: Drug: Administration of placebo;   Drug: Administration of etoricoxib
Outcome Measures: Post-operative opioid-sparing effect of etoricoxib in humans undergoing elective Tonsillectomy;   Impact of etoricoxib medication on PONV or activities of daily or the incidence of postoperative bleeding
18 Recruiting Measuring Pain and Hydration After Tonsillectomy
Condition: Dehydration
Intervention: Other: Hoist Group
Outcome Measures: Incidence of dehydration;   Patient reported pain level
19 Unknown  Inferior Turbinate Reduction in Pediatric Population Failing Tonsillectomy and Adenoidectomy for Sleep Disordered Breathing
Conditions: Sleep Related Breathing Disorder;   Upper Airway Resistance Syndrome;   Obstructive Sleep Apnea
Intervention: Procedure: Cold ablation inferior turbinate reduction utilizing radiofrequency ablation surgery (CITR).
Outcome Measure: resolution of obstructive sleep apnea symptoms on pediatric sleep questionaire
20 Recruiting Tramadol Infiltration for Tonsillectomy
Condition: Postoperative Pain
Interventions: Drug: Tramadol 2mg/kg;   Drug: Saline solution
Outcome Measure: Analgesic effect

These studies may lead to new treatments and are adding insight into Tonsillectomy etiology and treatment.

A major focus of Tonsillectomy research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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