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Toviaz Medical Research Studies

Up-to-date List of Toviaz Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Toviaz Medical Research Studies

Rank Status Study
1 Unknown  An Open Label Study to Measure Efficacy of Fesoterodine (Toviaz) Post Surgery for Benign Prostatic Hyperplasia
Condition: Bladder Outlet Obstruction
Intervention: Drug: Toviaz (Fesoterodine)
Outcome Measures: AUA symptom score;   Uroflowmetry and post-void residual
2 Recruiting A Study To Find Out How Fesoterodine Works In Children Aged 6 To 17 Years With Bladder Overactivity Caused By A Neurological Condition
Condition: Urinary Bladder, Neurogenic
Interventions: Drug: Fesoterodine PR 4 mg;   Drug: Fesoterodine PR 8 mg;   Drug: Oxybutynin;   Drug: Fesoterodine PR;   Drug: Fesoterodine BIC 2 mg;   Drug: Fesoterodine BIC 4 mg
Outcome Measures: Maximum cystometric bladder capacity;   Detrusor pressure at maximum bladder capacity;   Presence of involuntary detrusor contractions;   Bladder volume at first involuntary detrusor contraction;   Bladder compliance;   Mean number of micturitions and/or catheterizations/day;   Mean number of incontinence episodes/day;   Mean urgency episodes/day if applicable;   Mean volume voided per micturition or mean volume per catheterization
3 Unknown  Premarin Versus Toviaz for Treatment of Overactive Bladder
Condition: Overactive Bladder
Intervention: Drug: Toviaz, Premarin Vaginal Cream
Outcome Measures: Urinary frequency as measured by a 3 day voiding diary;   Lifestyle Impact of Overactive Bladder as measured using 3 validated questionnaires: OAB-Q, PPBC, and Urgency Severity and Impact Questionnaire
4 Unknown  Solifenacin Succinate Versus Fesoterodine A Comparison Trial for Urgency Symptoms
Condition: Urinary Bladder, Overactive
Interventions: Drug: solifenacin succinate;   Drug: fesoterodine
Outcome Measures: Changes in urgency sensation;   Adverse events
5 Not yet recruiting Study to Estimate the Relative Bioavailability Compared to Commercial Extended-release Tablet Formulation and the Effects of Food Or Sprinkling on Applesauce for Fesoterodine Sustained-release Beads-in-capsule Formulations in Healthy Adult Volunteers
Condition: Healthy
Interventions: Drug: Fesoterodine ER (fasted);   Drug: Fesoterodine SR3 (fasted);   Drug: Fesoterodine SR3 (fed);   Drug: Fesoterodine SR3 (sprinkle);   Drug: Fesoterodine SR4 (fasted);   Drug: Fesoterodine SR4 (fed);   Drug: Fesoterodine SR4 (sprinkle)
Outcome Measures: Area Under the Curve From Time Zero to Extrapolated Infinite Time [AUC (0 - 8)];   Maximum Observed Plasma Concentration (Cmax);   Area Under the Curve From Time Zero to Last Quantifiable Concentration (AUClast);   Time to Reach Maximum Observed Plasma Concentration (Tmax);   Plasma Decay Half-Life (t1/2)
6 Recruiting Understanding the Response to Fesoterodine Through Genetic Evaluation in the Elderly (URGE)
Condition: Urge Urinary Incontinence
Intervention: Drug: Fesoterodine Fumarate
Outcome Measure: Treatment Benefit Scale
7 Unknown  Validation of Instruments for Pragmatic Clinical Trials for Overactive Bladder
Condition: Overactive Bladder
Intervention: Drug: Toviaz
Outcome Measure: Clinical effectiveness The primary outcome for clinical effectiveness will be patient reported improvement in urinary urgency at 3 months compared to before start of treatment. On two pragmatic instruments, QVD and OAB-q clinical effectiveness will be
8 Recruiting A Study of the Effects of Fesoterodine in Men at High Risk for Overactive Bladder/Detrusor Overactivity Post Robotic-Assisted Laparoscopic Prostatectomy
Condition: Prostate Adenocarcinoma
Intervention: Drug: Fesoterodine
Outcome Measure: Number of Adverse Events
9 Recruiting Urinary Nerve Growth Factor (NGF), Prostaglandin E2 (PGE2)and Adenosine Triphosphate (ATP): Potential Biomarkers in Overactive Bladder Patients
Condition: Overactive Bladder
Intervention: Drug: Oxybutinin, Fesoterodine, Solifenacin, Propiverin, Trospium
Outcome Measure: NGF/creatinine, PGE2/creatinine and ATP/creatinine level at pre-treatment and post-treatment of overactive bladder patients.

These studies may lead to new treatments and are adding insight into Toviaz etiology and treatment.

A major focus of Toviaz research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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