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Trichomoniasis Medical Research Studies

Up-to-date List of Trichomoniasis Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Trichomoniasis Medical Research Studies

Rank Status Study
1 Unknown  Trichomoniasis: Genotype and Phenotype Correlations in African American Women
Condition: Trichomonas Infections
Outcome Measure: Correlation of Trichomonas genotype with clinical symptoms, HIV status and patient race.
2 Recruiting Trichomonas Vaginalis Repeat Infections Among HIV Negative Women
Conditions: Vaginitis Trichomonal or Due to Trichomonas;   Partner Communication
Interventions: Drug: MTZ 250 mg BID;   Drug: PDPT;   Drug: MTZ 2 g;   Other: Partner referral
Outcome Measure: TV negative after treatment with either multi or single dose MTZ
3 Recruiting DNA Clearance of Uncomplicated Trichomonas Vaginalis Infections in HIV Negative Women
Condition: Trichomonas Vaginalis
Outcome Measure: TV negative by PCR, post treatment
4 Recruiting Cepheid Rectal Sample Validation Study
Conditions: Gonorrhea;   Chlamydia;   Trichomonas
Intervention: Device: STD testing (GC/Ct/trich)
Outcome Measures: Rectal Gonorrhea/Chlamydia testing result;   pharyngeal GC/Ct result;   Trichomonas Testing Results
5 Unknown  Accuracy and Acceptability of Self-Diagnostic Methods for Vaginitis in Adolescent Females
Condition: Trichomonas Vaginalis
Intervention: Device: Point of care tests
Outcome Measures: Sensitivity of self performed rapid trichomonas tests;   Acceptability of self testing for trichomonas
6 Recruiting Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays
Conditions: Chlamydia Infections;   Gonorrhea;   Trichomonas Infections
Intervention: Device: APTIMA® Trichomonas vaginalis & APTIMA® COMBO 2® Assays
Outcome Measure: Qualitative detection of ribosomal RNA from Chlamydia trachomatis and/or Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) to aid in the diagnosis of chlamydial and/or gonococcal and/or trichomonal urogenital disease
7 Recruiting Safer Sex Program for Young African-American Men
Conditions: Gonorrhea;   Chlamydia;   Trichomoniasis;   Syphilis;   HIV Infections
Intervention: Behavioral: Intervention
Outcome Measure: The frequency of unprotected sex rather than frequency of condom use will be used as the primary outcome measure.
8 Recruiting Observational Program Neo-Penotran® Forte
Conditions: Vaginal Candidiasis;   Bacterial Vaginosis;   Trichomonal Vaginitis
Intervention: Drug: Metronidazole/Miconazole (Neo-Penotran Forte, BAY86-5276)
Outcome Measures: Percent rate of different vaginal infections;   Clinical characteristics of vaginitis after treatment.;   Change of microbiological characteristics after treatment;   Patient rating of tolerability and treatment results;   Physician's rating of tolerability and treatment results
9 Recruiting A Key Link for Transmission Prevention
Condition: HIV
Interventions: Behavioral: Standard HIV prevention messages;   Behavioral: 5 counselor-delivered sessions;   Drug: ARVs with raltegravir and emtricitabine/tenofovir disoproxil fumarate
Outcome Measures: Number of participants who screen and enroll into the study with acute HIV-infection (AHI).;   Proportion of participants in Arm BI who complete the behavioral sessions within 3 weeks of enrollment.;   Proportion of participants completing full course of ARVs in Arm BIA and the number and type of adverse events/social harms.;   Proportion of participants in Arm BIA who complete the behavioral sessions within 3 weeks of enrollment.;   Unprotected sexual acts assessed at weeks 12, 26, and 52.;   The number of partners reporting for HIV testing.;   Time to suppression of HIV RNA.;   Cumulative incidence of incident gonorrhea, chlamydial infection, Trichomoniasis, and herpes simplex virus type 2 at 26 and 52 weeks.;   Blood and genital HIV RNA concentration with area under the curve.;   Antiretroviral therapy (ART) resistance.;   Proportion of partners reporting for HIV testing.
10 Recruiting Four-Arm Randomized Control Trial of Brief MI Versus Couples-Based HIV/STI Prevention in South Africa
Condition: HIV Prevention
Interventions: Other: Testing and Counseling;   Behavioral: Brief Motivational Interview (BMI);   Behavioral: Integrated Family and Cognitive Behavioral Therapy
Outcome Measures: Biologically confirmed infectious disease status;   Condom use and sexual risk behavior;   Drug taking risk behavior;   Intimate partner violence
11 Recruiting Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis
Condition: Bacterial Vaginosis
Interventions: Drug: N-Acetyl cysteine;   Drug: Metronidazole + N-Acetyl cysteine;   Drug: metronidazole
Outcome Measures: recovery of BV;   prevention of recurrence
12 Recruiting Microfinance and Health Intervention Trial for Youth in Dar es Salaam, Tanzania
Conditions: Sexually Transmitted Infections;   Gender Based Violence Perpetration
Intervention: Behavioral: Microfinance and Health Leadership
Outcome Measures: Incidence of New Sexually Transmitted Infections;   Proportion of Men Reporting Perpetration of Physical, Sexual, or Psychological Partner Violence

These studies may lead to new treatments and are adding insight into Trichomoniasis etiology and treatment.

A major focus of Trichomoniasis research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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