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Triciribine Medical Research Studies

Up-to-date List of Triciribine Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Triciribine Medical Research Studies

Rank Status Study
1 Unknown  Influenza Virus Challenge Study to Test Monoclonal Antibody TCN-032 as a Treatment for Influenza
Condition: Influenza
Interventions: Biological: TCN-032;   Biological: Placebo (saline)
Outcome Measures: The primary objective is to evaluate the effect of TCN-032 compared to placebo in the development of clinical signs and symptoms of influenza (including upper respiratory, lower respiratory, systemic and fever).;   The main secondary objective is to evaluate the effect of TCN-032 compared to placebo in total virus shedding (measured by area under the curve [AUC]) from the nasal mucosa, measured by viral culture.;   Pharmacokinetics (PK) and immunogenicity of TCN-032;   Change in haemagglutination-inhibiting antibody (HAI) titre pre-challenge to Day 28.;   Development of viral resistance to TCN-032;   To evaluate the safety of subjects who undergo influenza A viral challenge, with or without treatment with TCN-032.;   The duration of influenza symptoms or pyrexia;   The time to peak of influenza symptoms or pyrexia;   The daily incidence of influenza symptoms or pyrexia.;   The proportion of the components of the primary objective: upper respiratory symptoms, lower respiratory symptoms, systemic influenza symptoms, pyrexia.;   The duration of the components of the primary objective: upper respiratory symptoms, lower respiratory symptoms, systemic influenza symptoms, pyrexia.;   The time to peak of the components of the primary objective: upper respiratory symptoms, lower respiratory symptoms, systemic influenza symptoms, pyrexia.;   The daily incidence of the components of the primary objective: upper respiratory symptoms, lower respiratory symptoms, systemic influenza symptoms, pyrexia.;   The proportion of any grade influenza symptoms, or pyrexia;   The duration of any grade influenza symptoms, or pyrexia;   The time to peak of any grade influenza symptoms, or pyrexia;   The daily incidence of any grade influenza symptoms, or pyrexia;   The peak value of virus shedding from the nasal mucosa measured by viral culture;   The time to peak of virus shedding from the nasal mucosa measured by viral culture;   The duration of virus shedding from the nasal mucosa measured by viral culture;   The daily incidence of virus shedding from the nasal mucosa measured by viral culture;   The AUC of virus shedding from the nasal mucosa measured by qPCR;   The peak value of virus shedding from the nasal mucosa measured by qPCR;   The time to peak of virus shedding from the nasal mucosa measured by qPCR;   The duration of virus shedding from the nasal mucosa measured by qPCR;   The daily incidence of virus shedding from the nasal mucosa measured by qPCR;   Incidence of seroconversion to viral challenge strain;   Incidence of seroprotection to viral challenge strain;   Total tissue count and total mucus weight after viral inoculation
2 Recruiting Linking Former Inmates to Primary Care
Conditions: Hypertension;   Substance Abuse;   Asthma;   Depression
Intervention: Other: Primary care redesign
Outcome Measures: Health outcomes;   Cost savings to the Centers for Medicare & Medicaid Services;   Health care utilization
3 Recruiting 12-Month Efficacy and Safety of Diepalrestat in Adults With Diabetic Peripheral Neuropathy, a DB, Placebo-Controlled Study
Condition: Diabetic Peripheral Neuropathy
Intervention: Drug: diepalrestat choline
Outcome Measures: change from baseline in peroneal motor nerve conduction velocity;   change from baseline in patient-reported Visual Acuity Scales;   change from baseline in patient-reported responses to Toronto Clinical Neuropathy Score (TCNS);   change from baseline in quality of life administered by SF-36 instrument;   change from baseline in conduction velocity measurements;   change in visual acuity compared to baseline;   change from baseline in conduction velocity measurement

These studies may lead to new treatments and are adding insight into Triciribine etiology and treatment.

A major focus of Triciribine research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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