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Ulone Medical Research Studies

Up-to-date List of Ulone Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Ulone Medical Research Studies

Rank Status Study
1 Recruiting A Study of Belimumab in Idiopathic Membranous Glomerulonephropathy
Condition: Glomerulonephritis, Membranous
Intervention: Drug: belimumab
Outcome Measures: Change from baseline in proteinuria levels at week 28;   Change from baseline in anti-PLA2R autoantibody titres at week 28;   Change from baseline in urine levels of belimumab at week 28;   Change from baseline in proteinuria levels;   Change from baseline in anti-PLA2R autoantibody titres;   Change from baseline in urine levels of belimumab;   Incidence of complete or partial remission;   Time to complete or partial remission;   Incidence of anti-PLA2R autoantibody remission:;   Incidence of anti-PLA2R autoantibody relapse (antibody detectable after previously undetectable);   Change from baseline in eGFR levels;   Change from baseline in serum creatinine levels;   Change from baseline in levels of serum albumin;   Change from baseline in levels of cholesterol;   Incidence of oedema (extending beyond calf);   Serum belimumab Cmax, Cmin, AUC(0-2), and urine Ae(0-24);   Change from baseline in SF-36 v2 Quality of Life (QoL) questionnaire score;   Pharmacodynamic/biomarker endpoints may include Urine membrane attack complex (MAC), B Cell and T Cell sub-populations, BLyS levels cytokines/chemokines antigen specific lymphocyte response, autoantibody profile, change in transcriptomics profile;   Safety and tolerability

These studies may lead to new treatments and are adding insight into Ulone etiology and treatment.

A major focus of Ulone research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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