Up-to-date List of Verorab Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Verorab Medical Research Studies

1 Recruiting Immunogenicity and Safety of Verorab® in a "One-week" Intradermal Post-exposure Prophylaxis Regimen
Condition: Rabies
Interventions: Biological: Purified Vero cell Rabies Vaccine (PVRV);   Biological: PVRV + purified Equine Rabies Immunoglobulin (pERIG)
Outcome Measures: Percentage of participants with seroprotection rate following PEP using Verorab® vaccine with or without pERIG Favirab®;   Seroprotection and geometric mean titers (GMTs) following primary and booster vaccination by Verorab® with or without Favirab® infiltration;   Occurrence and intensity of solicited injection site and systemic reactions and unsolicited adverse event s occurring after vaccination with Verorab® vaccine, with or without pERIG Favirab®
2 Unknown  Immunogenicity, Efficacy and Safety Study of an MSP3-LSP (Long Synthetic Peptide) Malaria Vaccine
Condition: Malaria
Interventions: Biological: MSP3 Long Synthetic Peptide 30 micrograms of MSP3 LSP;   Biological: Verorab vaccine
Outcome Measures: Number of clinical malaria episodes occurring during the consecutive malaria transmission season after the third vaccination;   Solicited adverse events measured from day 0 to day 7 after each dose;   Unsolicited adverse events measured up to one month after each dose;   Serious Adverse Events measured during the 12 months of study duration;   The humoral response to the vaccine antigen: assessed by measuring the level of IgG by ELISA;   IgG ability to recognize the native protein on Merozoite using Western Blot(WB) method;   Incidence of all clinical malaria episodes occurring through two transmission seasons subsequent to the 3 doses.
3 Unknown  Immunogenicity and Safety Study of A New Chromatographically Purified Vero Cell Rabies Vaccine With ID Regimen and ERIG
Conditions: Rabies;   Vaccine
Intervention: Biological: SPEEDA and TRCS SPEEDA
Outcome Measures: immunogenicity (the level of rabies neutralizing antibodies by RFFIT test);   safety
4 Unknown  Safety of Recombinant Hybrid GMZ 2 [GLURP + MSP 3] Blood Stage Malaria Vaccine
Condition: Malaria
Interventions: Biological: GMZ2 (malaria vaccine);   Biological: GMZ2 malaria vaccine;   Biological: Verorab vaccine
Outcome Measures: Local and systemic reactogenicity;   Unsolicited adverse events;   Occurrence of serious adverse events;   Biological safety;   Humoral immune response to GLURP and MSP 3;   Cellural immune response

These studies may lead to new treatments and are adding insight into Verorab etiology and treatment.

A major focus of Verorab research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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