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Vocal Cord Paralysis Medical Research Studies

Up-to-date List of Vocal Cord Paralysis Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Vocal Cord Paralysis Medical Research Studies

Rank Status Study
1 Unknown  Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis
Condition: Vocal Cord Paralysis
Outcome Measure:
2 Recruiting Implantation of Porous Titanium Prosthesis in Laryngeal Surgery
Condition: Vocal Cord Paralysis
Intervention: Device: Vocal fold medialization (thyroplasty) prosthesis by insertion of a new implant allowing very easy and quick setting
Outcome Measures: Nasofibroscopy;   Voice control and recording;   All types of complication
3 Not yet recruiting The Yield of Laryngeal Ultrasound in the Evaluation of Stridor and Dysphonia in Children
Conditions: Stridor;   Vocal Cord Paralysis
Outcome Measure: The number of participants that will be diagnosed with anatomical and functional causes of stridor and dysphonia by US in comparisom with ANL
4 Unknown  Dynamic Laryngeal Opening for Bilateral Vocal Fold Paralysis by an Implanted Stimulator
Condition: Vocal Cord Paralysis
Intervention: Device: pacemaker
Outcome Measures: Videotaping vocal cords and pulmonary function tests;   Tolerance of implanted device
5 Unknown  Unusual Clinical Findings of Herpes Esophagitis
Conditions: Herpes Esophagitis;   Vocal Fold Palsy
Outcome Measure:
6 Not yet recruiting Cough in Reduced True Vocal Fold Mobility
Conditions: Unilateral Vocal Cord Paresis;   Unilateral Vocal Cord Paralysis
Interventions: Other: cough airflow measure;   Other: vocal tasks;   Other: true vocal fold movement;   Other: spirometry test;   Other: maximum expiratory pressure (MEP)
Outcome Measures: Peak expiratory flow rate (PEFR);   True vocal fold maximum abduction angles in inspiratory phase;   True vocal fold maximum abduction angles in expiratory phase;   True vocal fold maximum adduction angles in compression phase;   Peak expiratory flow rise time (PEFRT);   Cough volume acceleration (CVA);   Expiratory phase duration;   Peak expiratory flow;   Maximum expiratory pressure;   Degree of glottal closure;   Forced vital capacity (FVC);   Forced expired volume within 1 second (FEV1);   The ratio FEV1/FVC
7 Recruiting Establish Quantitative Measurements of Laryngeal Sensorimotor Functions and Evaluating the Grade of Phonation and Swallowing Impairment
Condition: Unilateral Vocal Cord Paralysis
Outcome Measures: Fiberoptic endoscopic evaluation of swallowing (FEES);   Laryngo-pharyngeal mucosa sensation test;   laryngeal electromyography;   laboratory voice analysis;   voice range profile;   Voice Handicap Index (VHI);   Disease related life quality assessment: FACT-H&N, FACT-E
8 Not yet recruiting Neural Monitoring of the Superior Laryngeal Nerve in Thyroid Surgery
Conditions: Laryngeal Nerve;   Thyroid Surgery
Intervention: Procedure: Monitoring
Outcome Measure: Intact external branch of the superior laryngeal nerve
9 Recruiting Selective Bilateral Laryngeal Reinnervation as a Secondary Treatment in Case of Bilateral Vocal Fold Paralysis
Condition: Bilateral Vocal Fold Paralysis
Intervention: Procedure: Surgery for bilateral laryngeal reinnervation
Outcome Measures: Maximal phonation time;   Voice quality assessed using quality of life questionnaire;   Voice quality assessed using computerized analysis;   Voice quality assessed using swallowing scores
10 Not yet recruiting Comparison of the Vocal Cord Imaging Techniques After Thyroidectomy
Condition: Thyroid Nodule
Interventions: Device: direct laringoscope;   Device: fiberoptic nasal laringoscope;   Device: video laringoscope;   Device: ultrasonograph
Outcome Measures: visualisation of the vocal cords;   duration of the procedure;   mean arterial pressure;   heart rate;   peripheal oxygen saturation;   hypertention;   tachycardia;   laceration;   broken teeht

These studies may lead to new treatments and are adding insight into Vocal Cord Paralysis etiology and treatment.

A major focus of Vocal Cord Paralysis research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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