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Dysgeusia Medical Research Studies

Up-to-date List of Dysgeusia Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Dysgeusia Medical Research Studies

Rank Status Study
1 Unknown  Effect of Chemotherapy With Paclitaxel/Cisplatin on Development Dysgeusia in Non Small Cell Lung Cancer
Conditions: Non-Small Cell Lung Cancer;   Dysgeusia;   Taste Disorders;   Lung Neoplasms;   Small Cell Lung Carcinoma
Intervention:
Outcome Measures: Dysgeusia;   Body composition;   Body Mass Index;   weight loss;   Subjective Global Assessment;   proportion of Anorexia;   energy and nutrimental consumption;   quality o f life
2 Recruiting Bovine Lactoferrin in Reducing Taste Disturbances in Patients With Colorectal Cancer Receiving Oxaliplatin-Based Chemotherapy
Conditions: Colorectal Cancer;   Dysgeusia;   Oral Complications of Chemotherapy
Interventions: Other: questionnaire administration;   Procedure: quality-of-life assessment;   Other: laboratory biomarker analysis;   Biological: bovine lactoferrin
Outcome Measures: Change in the Taste Visual Analog Scale (VAS) and taste and smell questionnaire responses;   Effect of bovine lactoferrin on lipid peroxidation byproducts in saliva as measured by the TBARs assay;   Malondialdehyde (MDA) concentrations before and after a ferrous iron oral rinse;   Quality of life as quantified by the Functional Assessment of Anorexia/Cachexia Treatment (FAACT) questionnaire
3 Recruiting Taste Disorders in Middle Ear Disease and After Middle Ear Surgery
Condition: Taste Disturbance
Interventions: Other: taste measurement;   Other: Symptom questionnaire;   Behavioral: Quality of life questionnaire;   Other: Nerve sample
Outcome Measures: Taste disturbance;   Quality of life;   Histopathological changes
4 Recruiting Bovine Lactoferrin Supplement in Improving Taste in Patients With Cancer Receiving Chemotherapy
Conditions: Anorexia;   Cachexia;   Malignant Neoplasm;   Oral Complications of Chemotherapy
Interventions: Biological: bovine lactoferrin supplement;   Other: questionnaire administration;   Procedure: quality-of-life assessment;   Other: laboratory biomarker analysis
Outcome Measures: Change in taste disturbances using the visual analogue scale (VAS) and the Smell and Taste Questionnaire;   Change in smell disturbances using the VAS and the Smell and Taste Questionnaire;   Effect of bovine lactoferrin supplement on lipid peroxidation byproducts as measured by the TBARs assay;   Malondialdehyde (MDA) concentrations before and after a ferrous iron oral rinse;   Smelling loss as quantified by the Brief Smell Identification Test (B-SIT);   Quality of life as quantified by the Functional Assessment of Anorexia/Cachexia Treatment (FAACT) and Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity (FACT/GOG-Ntx) questionnaires
5 Recruiting Investigation of the Effects of Bariatric Surgery on Taste Reward in Humans
Condition: Obesity
Intervention:
Outcome Measures: Breakpoints;   Hunger;   Body mass index
6 Not yet recruiting Cetuximab Compared to Mitomycin-C and 5-Fluorouracil for Locally Advanced Squamous Cell Carcinomas of the Head and Neck
Condition: Head and Neck Neoplasms
Interventions: Drug: Cetuximab;   Drug: Mitomycin-C/ 5-Fluorouracil
Outcome Measures: Quality of Life;   Efficacy of Cetuximab plus radiation therapy;   Equality in therapy of Cetuximab plus radiation therapy versus Mitomycin C/5-Fluorouracil plus radiation therapy.

These studies may lead to new treatments and are adding insight into Dysgeusia etiology and treatment.

A major focus of Dysgeusia research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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