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Mellitus Medical Research Studies

Up-to-date List of Mellitus Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Mellitus Medical Research Studies

Rank Status Study
1 Recruiting Prospective Cohort Study of the Body Constitution Among Type II Diabetes Mellitus Patients
Condition: Diabetes Mellitus
Intervention:
Outcome Measures: Body constitution of type II diabetes Mellitus patients;   All cause mortality of type II diabetes Mellitus patients;   Life quality of diabetes Mellitus patients;   Diabetic retinopathy of type II diabetes Mellitus patients;   Diabetic nephropathy of type II diabetes Mellitus patients;   Diabetic neuropathy of type II diabetes Mellitus patients
2 Unknown  Educational Intervention and Social Support in Diabetes Mellitus
Condition: Diabetes Mellitus
Interventions: Other: Educational intervention for family members/caregivers of people with diabetes Mellitus through telephone contact;   Other: Educational intervention group for people with diabetes through Diabetes Conversation Maps
Outcome Measures: glycated hemoglobin;   fasting plasma glucose;   triglycerides;   total cholesterol and fractions;   microalbuminuria;   urea;   creatinine;   body mass index;   waist circumference;   blood pressure;   Perceived Self-Efficacy: Diabetes Management Self-efficacy Scale for Patients with Type 2 Diabetes Mellitus;   Knowledge about diabetes Mellitus: Diabetes Mellitus knowledge (DKN-A);   Adherence to medication treatment: Self-Reported Measure of Medication Adherence (Measure of Treatment Adherence - MTA);   Adherence to self care: Summary of Diabetes Self-Care Activities Questionnaire (SDSCA) ( Diabetes Self-Care Activities Questionnaire);   Perception of stress: Perceived Stress Scale (Perceived Stress Scale);   Ways of coping: Ways of Coping Scale (Ways of Coping Scale);   Acceptance of Illness (Acceptance of Illness Scale);   Perception of social support: The Social Support Network Inventory;   Self-monitoring of blood glucose
3 Recruiting Effect of Linagliptin on Insulin Sensitivity and Pancreatic Beta Cell Function in Patients With Type 2 Diabetes Mellitus
Conditions: Type 2 Diabetes Mellitus;   Insulin Sensitivity/Resistance
Interventions: Drug: Linagliptin;   Drug: Placebo;   Drug: Voglibose
Outcome Measures: To study the effect of Linagliptin on insulin sensitivity by performing euglycemic hyperinsulinemic clamp in patients with type 2 diabetes Mellitus.;   To study the effects of Linagliptin on glycemic control and beta cell function in patients with type 2 diabetes Mellitus 6 months
4 Unknown  Assessment of Surface Coverage of Two Types of DES in Diabetes Mellitus and Non- Diabetes Mellitus
Conditions: Coronary Artery Disease;   Diabetes Mellitus
Intervention: Device: Device: Polymer-based sirolimus-eluting stent(Cypher stent ) and Polymer-free paclitaxel-eluting stent (YinYi stent)
Outcome Measures: To investigate the difference of surface coverage pattern between diabetic patients and non-diabetic patients after DES (Cypher stent or YINYI stent)implantation;   To investigate the difference of surface coverage pattern between diabetic patients and non-diabetic patients after DES (Cypher stent or YINYI stent) implantation;   To investigate the incidence of malapposition between diabetic patients and non-diabetic patients after DES (Cypher stent or YINYI stent) implantation;   To investigate the differences of surface coverage pattern,the incidence of malapposition and in-stent thrombosis between Cypher stent and YINYI in diabetic patients;   To investigate the differences of surface coverage pattern,malapposition and the incidence of thrombosis between Cypher stent and YINYI in non-diabetic patients
5 Unknown  Comparison of Diabetes Mellitus and Non-diabetes Mellitus Patients for DES Surface COVERage by OCT
Conditions: Coronary Heart Disease;   Diabetes Mellitus
Intervention: Device: Polymer-based sirolimus-eluting stent(Cypher stent ) and Polymer-free paclitaxel-eluting stent (YinYi stent)
Outcome Measures: Comparison of the surface coverage between DM and Non-DM at 6 months after Cypher and YINYI stent implantation using OCT.;   Comparison of troponin-I levels between DM and Non-DM at baseline, 8 hours, 16 hours and 24 hours after stent implantation;   Comparison of hsCRP concentration between DM and Non-DM at baseline, 8 hours, 16 hours and 24 hours after stent implantation;   Comparison of the malapposition, neointimal heterogeneity and the incidence of thrombosis between DM and Non-DM patients after Cypher and YINYI implantation using OCT;   Comparison of surface coverage, late stent malapposition, neointimal heterogeneity and the incidence of thrombosis between Cypher and YINYI in DM after stenting using OCT;   Comparison of surface coverage, late stent malapposition, neointimal heterogeneity, and the incidence of thrombosis between Cypher and YINYI in Non-DM after stenting using OCT;   QCA parameters and IVUS parameters for binary restenosis, late lumen loss.;   Comparison of the surface coverage, late stent malapposition, neointimal heterogeneity, and the incidence of thrombosis between DM and Non-DM patients after Cypher and YINYI implantation using OCT;   Comparison of surface coverage, late stent malapposition, neointimal heterogeneity, and the incidence of thrombosis between Cypher and YINYI in DM after stenting using OCT;   TLR/TVR;   MACE
6 Unknown  Psychosocial Interventions in the Treatment of Youth With Type 1 Diabetes Mellitus
Condition: Diabetes Mellitus
Intervention: Behavioral: psychosocial intervention
Outcome Measure:
7 Recruiting Predictors of Future Type 2 Diabetes Mellitus in Circassians Minority in Israel
Condition: Diabetes Mellitus Type II
Intervention: Other: NONE intervention
Outcome Measure: New incidences of Type II Diabetes Mellitus in Circassians minority in Israel
8 Recruiting Prospective Study on Diabetes Mellitus and Its Complications in Newly Diagnosed Adult Patients
Conditions: Diabetes Mellitus, Type 1;   Diabetes Mellitus, Type 2
Intervention:
Outcome Measures: Change of insulin sensitivity (M-Value);   Change of insulin secretion;   Incidence of any diabetic complication
9 Recruiting Study of Subcutaneous Doses of HIP2B in Subjects With Type 2 Diabetes Mellitus Treated With Metformin
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: HIP2B;   Drug: Placebo
Outcome Measures: The safety and tolerability of repeat doses of HIP2B in subjects with type 2 diabetes Mellitus.;   Glucose-stimulated insulin secretion.
10 Not yet recruiting Long Term Effects of Gestational Diabetes Mellitus in a Population of Parous Women
Condition: Gestational Diabetes Mellitus
Intervention:
Outcome Measure: Long term effects of gestational diabetes Mellitus in a population of parous women
11 Unknown  Prevention of Diabetes Mellitus Development in Women Who Had Already Experienced A Gestational Diabetes
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Metformin;   Behavioral: Lifestyle intervention - diet, physical activity
Outcome Measures: Incidence of type 2 diabetes Mellitus.;   Incidence of IGT
12 Recruiting Clinical Trial of Efficiency and Safety of Subetta in the Combined Treatment of Patients With Type II Diabetes Mellitus
Condition: Type II Diabetes Mellitus
Interventions: Drug: Subetta;   Drug: Placebo
Outcome Measures: Changes in the mean value of HbA1c;   Fasting plasma glucose;   Records of the 7-point patient self-monitoring of blood glucose (SMBG) and average daily blood glucose;   Mean value of C-peptide;   Proportion of patients with increased and reduced level of C-peptide;   Concentrations of plasma total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides;   Changes in dosage of insulin (total daily dose insulin measured in IU and IU/ kg of body weight);   Proportion of patients with changed daily dose of per oral blood sugar- lowering drugs;   Changes in the mean absolute value of body weight (kg) and body build index (kg/m^2);   Changes in the satisfaction of diabetes treatment
13 Recruiting Clinical Trial of Efficiency and Safety of Subetta in the Combined Treatment of Patients With Type I Diabetes Mellitus
Condition: Type I Diabetes Mellitus
Interventions: Drug: Subetta;   Drug: Placebo
Outcome Measures: Changes in the mean value of HbA1c;   Fasting plasma glucose (based on the data of biochemical analysis);   Records of the 7-point patient self-monitoring of blood glucose (SMBG) and average daily blood glucose;   Mean value of C-peptide;   Concentrations of plasma total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides;   Changes in dosage of insulin (basal, prandial and total daily dose insulin measured in IU and IU/kg of body weight);   Changes in the satisfaction of diabetes treatment
14 Recruiting Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
Conditions: Gestational Diabetes Mellitus;   Type 2 Diabetes Mellitus;   Metabolic Syndrome;   Impaired Glucose Tolerance;   Disorder of Glucose Regulation
Interventions: Drug: Metformin XR plus placebo;   Drug: Metformin XR plus liraglutide
Outcome Measures: An index of insulin secretion in relation to insulin resistance (IS-SI) will be calculated;   Insulin resistance -baseline {HOMA-IR} and composite insulin sensitivity index [ISIOGTT], and pancreatic ß-cell function (corrected insulin response [CIRglupeak] and insulinogenic index [IGI])/HOMA-IR;   Cardiometabolic risk measures;   Anthropometric measurements;   Development of dysglycemia
15 Recruiting A Study to Evaluate AZP531 in Healthy, Overweight/Obese Patients With Type 2 Diabetes Mellitus
Condition: Overweight, Obesity, Type 2 Diabetes Mellitus
Intervention: Drug: AZP-531
Outcome Measures: To investigate the number of adverse events of single and multiple ascending doses AZP-531 in healthy volunteers, in overweight/obese volunteers, in patients with type 2 diabetes Mellitus.;   To determine the plasma pharmacokinetic (PK) profile of AZP-531 after single and multiple doses
16 Not yet recruiting Acute Effect of Phototherapy With Light Emitting Diode (LED) on Muscle and Pulmonary Oxygen Consumption on Diabetes Mellitus
Condition: Type 2 Diabetes Mellitus
Interventions: Device: Phototherapy through light emitting diode (LED);   Device: Placebo phototherapy
Outcome Measures: Change in muscle oxygen uptake after phototherapy and placebo phototherapy with light emitting diode (LED);   Change in pulmonary oxygen uptake after phototherapy and placebo phototherapy with light emitting diode (LED)
17 Unknown  Efficacy and Safety Study of Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) to Treat Type 2 Diabetes Mellitus
Condition: Type 2 Diabetes Mellitus - Poor Control
Intervention: Procedure: Laparoscopic Roux en Y gastric Bypass
Outcome Measure: Gastric Bypass in the Treatment of Type 2 Diabetes in Patients with a BMI of 25 to 35 kg/m2
18 Recruiting Perioperative Insulin, GIK or GLP-1 Treatment in Diabetes Mellitus
Condition: Diabetes Mellitus Type II
Interventions: Drug: Liraglutide;   Drug: Insulin bolus;   Drug: GIK infusion
Outcome Measures: Median glucose;   Total Insulin administration;   Postoperative complications;   Hypoglycemia;   Hypo- and hyperkalemia
19 Unknown  Evaluate the Side Effects and Benefits of RAS 130 With or Without Diet and Exercise in Type II Diabetes Mellitus
Condition: Type II Diabetes Mellitus
Intervention: Other: RAS 130 with diet and exercise
Outcome Measures: To determine cardiovascular side effects such as coronary artery disease (CAD) and congestive heart failure (CHF) in patients treated with RAS 130 along with diet and exercise.;   To determine the effect of RAS 130 on reduction of blood glucose level with or without diet and exercise
20 Not yet recruiting OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus
Conditions: Chronic Low Back Pain;   Type 2 Diabetes Mellitus
Interventions: Other: Osteopathic Manual Treatment (OMT);   Other: Sham OMT
Outcome Measures: Change in low back pain severity;   Change in back-specific functioning;   Change in general health;   Change in glycemic control;   Tissue texture changes;   Change in biomarker concentrations

These studies may lead to new treatments and are adding insight into Mellitus etiology and treatment.

A major focus of Mellitus research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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