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Diclofenac Side Effects List

Common Diclofenac Side Effects


The following Diclofenac Side Effects were reported by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers) and manufacturers.

It is important to know potential risks posed by drugs and health products. Staying informed can help you make right decisions and stay healthy.

You can read detailed reports by clicking on a side effect.




Abasia 9 reports0.11%
Abdominal Discomfort 28 reports0.33%
Abdominal Distension 31 reports0.36%
Abdominal Pain 139 reports1.62%
Abdominal Pain Lower 28 reports0.33%
Abdominal Pain Upper 77 reports0.90%
Abdominal Rigidity 7 reports0.08%
Abdominal Sepsis 12 reports0.14%
Abdominal Tenderness 24 reports0.28%
Abscess 12 reports0.14%
Acidosis 10 reports0.12%
Acquired Haemophilia 9 reports0.11%
Activated Partial Thromboplastin Time Prolonged 16 reports0.19%
Acute Coronary Syndrome 13 reports0.15%
Acute Hepatic Failure 12 reports0.14%
Acute Myocardial Infarction 21 reports0.25%
Acute Respiratory Distress Syndrome 12 reports0.14%
Adhesion 10 reports0.12%
Agranulocytosis 21 reports0.25%
Alanine Aminotransferase Increased 49 reports0.57%
Altered State Of Consciousness 7 reports0.08%
Anaemia 86 reports1.00%
Anaphylactic Reaction 62 reports0.72%
Anaphylactic Shock 16 reports0.19%
Angina Pectoris 11 reports0.13%
Angioedema 26 reports0.30%
Anorexia 23 reports0.27%
Antinuclear Antibody Increased 7 reports0.08%
Antisocial Behaviour 7 reports0.08%
Anuria 21 reports0.25%
Anxiety 9 reports0.11%
Areflexia 12 reports0.14%
Arteriospasm Coronary 8 reports0.09%
Arthralgia 53 reports0.62%
Arthritis 8 reports0.09%
Ascites 31 reports0.36%
Aspartate Aminotransferase Increased 40 reports0.47%
Asthenia 50 reports0.58%
Asthma 10 reports0.12%
Atelectasis 7 reports0.08%
Atrial Fibrillation 33 reports0.39%
Atrial Septal Defect 10 reports0.12%
Back Pain 43 reports0.50%
Bedridden 7 reports0.08%
Blister 30 reports0.35%
Blood Albumin Decreased 25 reports0.29%
Blood Albumin Increased 8 reports0.09%
Blood Alkaline Phosphatase Increased 47 reports0.55%
Blood Bicarbonate Decreased 8 reports0.09%
Blood Bilirubin Increased 27 reports0.32%
Blood Calcium Decreased 9 reports0.11%
Blood Cholesterol Increased 7 reports0.08%
Blood Creatine Phosphokinase Increased 25 reports0.29%
Blood Creatinine Increased 88 reports1.03%
Blood Fibrinogen Increased 8 reports0.09%
Blood Glucose Increased 25 reports0.29%
Blood Immunoglobulin E Increased 8 reports0.09%
Blood Lactate Dehydrogenase Increased 22 reports0.26%
Blood Lactic Acid Increased 9 reports0.11%
Blood Potassium Increased 27 reports0.32%
Blood Pressure Decreased 41 reports0.48%
Blood Pressure Increased 36 reports0.42%
Blood Sodium Decreased 21 reports0.25%
Blood Urea Increased 76 reports0.89%
Bone Marrow Failure 7 reports0.08%
Bone Pain 12 reports0.14%
Bradycardia 17 reports0.20%
Brain Oedema 9 reports0.11%
Bronchitis 8 reports0.09%
Bronchospasm 16 reports0.19%
Burning Sensation 13 reports0.15%
C-reactive Protein Increased 43 reports0.50%
Caesarean Section 14 reports0.16%
Cardiac Arrest 44 reports0.51%
Cardiac Failure 22 reports0.26%
Cardiac Failure Congestive 14 reports0.16%
Cardio-respiratory Arrest 13 reports0.15%
Cardiomyopathy 7 reports0.08%
Cardiovascular Disorder 8 reports0.09%
Cellulitis 13 reports0.15%
Cerebral Haemorrhage 8 reports0.09%
Cerebral Infarction 9 reports0.11%
Cerebrovascular Accident 11 reports0.13%
Chest Discomfort 17 reports0.20%
Chest Pain 54 reports0.63%
Chills 19 reports0.22%
Cholecystitis 8 reports0.09%
Cholelithiasis 8 reports0.09%
Chromaturia 15 reports0.18%
Chronic Obstructive Pulmonary Disease 12 reports0.14%
Circulatory Collapse 35 reports0.41%
Coagulopathy 11 reports0.13%
Cold Sweat 7 reports0.08%
Colitis 26 reports0.30%
Colitis Collagenous 9 reports0.11%
Colitis Ischaemic 11 reports0.13%
Colitis Ulcerative 12 reports0.14%
Colonic Stenosis 39 reports0.46%
Coma 15 reports0.18%
Completed Suicide 22 reports0.26%
Condition Aggravated 39 reports0.46%
Confusional State 43 reports0.50%
Constipation 20 reports0.23%
Contusion 9 reports0.11%
Convulsion 43 reports0.50%
Coronary Artery Disease 16 reports0.19%
Cough 22 reports0.26%
Crepitations 8 reports0.09%
Cyanosis 11 reports0.13%
Death 8 reports0.09%
Debridement 9 reports0.11%
Decreased Appetite 35 reports0.41%
Deep Vein Thrombosis 22 reports0.26%
Dehydration 82 reports0.96%
Delirium 11 reports0.13%
Depressed Level Of Consciousness 13 reports0.15%
Depression 32 reports0.37%
Dermatitis Exfoliative 9 reports0.11%
Diabetes Insipidus 10 reports0.12%
Diabetes Mellitus 8 reports0.09%
Diabetes Mellitus Insulin-dependent 8 reports0.09%
Diabetic Ketoacidosis 7 reports0.08%
Dialysis 7 reports0.08%
Diarrhoea 136 reports1.59%
Diarrhoea Haemorrhagic 10 reports0.12%
Diplopia 17 reports0.20%
Disinhibition 7 reports0.08%
Disorientation 18 reports0.21%
Disseminated Intravascular Coagulation 31 reports0.36%
Diverticulum 7 reports0.08%
Dizziness 72 reports0.84%
Duodenal Perforation 8 reports0.09%
Duodenal Stenosis 17 reports0.20%
Duodenal Ulcer 35 reports0.41%
Duodenal Ulcer Haemorrhage 15 reports0.18%
Duodenal Ulcer Perforation 20 reports0.23%
Duodenitis 10 reports0.12%
Dysarthria 8 reports0.09%
Dysgeusia 8 reports0.09%
Dyspepsia 19 reports0.22%
Dysphagia 11 reports0.13%
Dysphonia 8 reports0.09%
Dyspnoea 103 reports1.20%
Dyspnoea Exertional 8 reports0.09%
Ecthyma 19 reports0.22%
Electrocardiogram Abnormal 10 reports0.12%
Electrocardiogram St Segment Elevation 15 reports0.18%
Embolia Cutis Medicamentosa 54 reports0.63%
Encephalopathy 13 reports0.15%
Endoscopy Abnormal 13 reports0.15%
Enteritis 9 reports0.11%
Eosinophilia 14 reports0.16%
Epistaxis 15 reports0.18%
Erosive Duodenitis 8 reports0.09%
Erosive Oesophagitis 7 reports0.08%
Erythema 60 reports0.70%
Erythema Multiforme 8 reports0.09%
Eschar 15 reports0.18%
Exposure During Pregnancy 9 reports0.11%
Eye Haemorrhage 12 reports0.14%
Eye Swelling 14 reports0.16%
Eyelid Oedema 7 reports0.08%
Eyelid Ptosis 7 reports0.08%
Face Oedema 15 reports0.18%
Faeces Discoloured 18 reports0.21%
Fall 48 reports0.56%
Fatigue 60 reports0.70%
Feeling Abnormal 30 reports0.35%
Feeling Hot 9 reports0.11%
Fibrin D Dimer Increased 7 reports0.08%
Fibrosis 16 reports0.19%
Flatulence 9 reports0.11%
Fluid Intake Reduced 7 reports0.08%
Fluid Retention 7 reports0.08%
Flushing 7 reports0.08%
Gait Disturbance 22 reports0.26%
Gamma-glutamyltransferase Increased 14 reports0.16%
Gangrene 11 reports0.13%
Gastric Disorder 8 reports0.09%
Gastric Haemorrhage 35 reports0.41%
Gastric Ulcer 68 reports0.79%
Gastric Ulcer Haemorrhage 16 reports0.19%
Gastric Ulcer Perforation 23 reports0.27%
Gastritis 46 reports0.54%
Gastritis Erosive 9 reports0.11%
Gastroenteritis 7 reports0.08%
Gastrointestinal Disorder 68 reports0.79%
Gastrointestinal Erosion 33 reports0.39%
Gastrointestinal Haemorrhage 102 reports1.19%
Gastrointestinal Inflammation 28 reports0.33%
Gastrointestinal Mucosal Exfoliation 16 reports0.19%
Gastrointestinal Necrosis 11 reports0.13%
Gastrointestinal Ulcer 8 reports0.09%
Gastrointestinal Ulcer Haemorrhage 7 reports0.08%
Glasgow Coma Scale Abnormal 9 reports0.11%
Glomerulonephritis Minimal Lesion 8 reports0.09%
Grand Mal Convulsion 10 reports0.12%
Haematemesis 64 reports0.75%
Haematochezia 24 reports0.28%
Haematocrit Decreased 11 reports0.13%
Haematoma 11 reports0.13%
Haematuria 7 reports0.08%
Haemodialysis 24 reports0.28%
Haemoglobin Decreased 103 reports1.20%
Haemolysis 7 reports0.08%
Haemorrhage 28 reports0.33%
Hallucination 8 reports0.09%
Headache 47 reports0.55%
Heart Rate Decreased 10 reports0.12%
Heart Rate Increased 34 reports0.40%
Hepatic Enzyme Increased 11 reports0.13%
Hepatic Failure 21 reports0.25%
Hepatic Steatosis 8 reports0.09%
Hepatitis 14 reports0.16%
Hepatomegaly 9 reports0.11%
Hepatotoxicity 7 reports0.08%
Herpes Zoster 17 reports0.20%
Hiatus Hernia 10 reports0.12%
Hyperhidrosis 22 reports0.26%
Hyperkalaemia 35 reports0.41%
Hypersensitivity 35 reports0.41%
Hypertension 36 reports0.42%
Hypoaesthesia 18 reports0.21%
Hypoalbuminaemia 11 reports0.13%
Hypoglycaemia 13 reports0.15%
Hyponatraemia 16 reports0.19%
Hypoproteinaemia 17 reports0.20%
Hypotension 57 reports0.67%
Ileal Stenosis 16 reports0.19%
Ileal Ulcer 8 reports0.09%
Ileus 10 reports0.12%
Incorrect Dose Administered 7 reports0.08%
Infection 14 reports0.16%
Inflammation 20 reports0.23%
Influenza Like Illness 8 reports0.09%
Injection Site Discolouration 8 reports0.09%
Injection Site Erythema 12 reports0.14%
Injection Site Necrosis 21 reports0.25%
Injection Site Pain 32 reports0.37%
Injection Site Reaction 7 reports0.08%
Injury 8 reports0.09%
Insomnia 14 reports0.16%
Intentional Overdose 12 reports0.14%
International Normalised Ratio Increased 18 reports0.21%
Intestinal Diaphragm Disease 7 reports0.08%
Intestinal Perforation 9 reports0.11%
Intestinal Stenosis 10 reports0.12%
Intestinal Ulcer 29 reports0.34%
Intra-uterine Death 7 reports0.08%
Iron Deficiency Anaemia 31 reports0.36%
Jaundice 25 reports0.29%
Jejunal Ulcer 8 reports0.09%
Joint Swelling 16 reports0.19%
Kounis Syndrome 14 reports0.16%
Lactic Acidosis 40 reports0.47%
Large Intestinal Stenosis 8 reports0.09%
Large Intestinal Ulcer 25 reports0.29%
Large Intestine Perforation 31 reports0.36%
Lethargy 21 reports0.25%
Leukocytoclastic Vasculitis 12 reports0.14%
Leukocytosis 21 reports0.25%
Leukopenia 9 reports0.11%
Linear Iga Disease 18 reports0.21%
Lip Swelling 16 reports0.19%
Liver Disorder 20 reports0.23%
Liver Function Test Abnormal 25 reports0.29%
Liver Injury 10 reports0.12%
Local Swelling 9 reports0.11%
Loss Of Consciousness 49 reports0.57%
Lymphadenopathy 9 reports0.11%
Malaise 83 reports0.97%
Mallory-weiss Syndrome 9 reports0.11%
Maternal Exposure During Pregnancy 8 reports0.09%
Melaena 56 reports0.65%
Metabolic Acidosis 46 reports0.54%
Migraine 9 reports0.11%
Mobility Decreased 9 reports0.11%
Mouth Ulceration 11 reports0.13%
Mucosal Ulceration 9 reports0.11%
Multi-organ Failure 33 reports0.39%
Muscle Spasms 14 reports0.16%
Muscular Weakness 16 reports0.19%
Musculoskeletal Pain 13 reports0.15%
Myalgia 25 reports0.29%
Mydriasis 9 reports0.11%
Myocardial Infarction 23 reports0.27%
Myocardial Ischaemia 14 reports0.16%
Myoclonus 9 reports0.11%
Nausea 88 reports1.03%
Necrosis 15 reports0.18%
Necrotising Fasciitis 17 reports0.20%
Neonatal Respiratory Distress Syndrome 11 reports0.13%
Nephrolithiasis 12 reports0.14%
Nephropathy Toxic 9 reports0.11%
Nephrotic Syndrome 16 reports0.19%
Neutropenia 26 reports0.30%
No Therapeutic Response 13 reports0.15%
Obstruction Gastric 14 reports0.16%
Oedema 35 reports0.41%
Oedema Peripheral 51 reports0.60%
Oesophagitis 11 reports0.13%
Off Label Use 11 reports0.13%
Oligohydramnios 17 reports0.20%
Osteoarthritis 19 reports0.22%
Overdose 21 reports0.25%
Oxygen Saturation Decreased 12 reports0.14%
Pain 60 reports0.70%
Pain In Extremity 36 reports0.42%
Pallor 27 reports0.32%
Palpitations 8 reports0.09%
Pancreatitis Acute 8 reports0.09%
Pancytopenia 12 reports0.14%
Paraesthesia 14 reports0.16%
Peptic Ulcer 10 reports0.12%
Pericarditis 19 reports0.22%
Peritonitis 41 reports0.48%
Petechiae 28 reports0.33%
Pharyngeal Oedema 8 reports0.09%
Platelet Count Decreased 13 reports0.15%
Pleural Effusion 18 reports0.21%
Pneumonia 25 reports0.29%
Pneumoperitoneum 9 reports0.11%
Poisoning 9 reports0.11%
Porphyria Acute 11 reports0.13%
Post Procedural Bile Leak 8 reports0.09%
Post Procedural Complication 12 reports0.14%
Post Procedural Haemorrhage 10 reports0.12%
Proteinuria 13 reports0.15%
Prothrombin Time Prolonged 9 reports0.11%
Pruritus 79 reports0.92%
Pseudomonas Infection 9 reports0.11%
Pulmonary Embolism 20 reports0.23%
Pulmonary Oedema 12 reports0.14%
Purpura 8 reports0.09%
Pyrexia 61 reports0.71%
Rash 53 reports0.62%
Rash Erythematous 13 reports0.15%
Rash Macular 9 reports0.11%
Rash Pruritic 12 reports0.14%
Rectal Haemorrhage 25 reports0.29%
Red Blood Cell Sedimentation Rate Increased 10 reports0.12%
Renal Disorder 11 reports0.13%
Renal Failure 45 reports0.53%
Renal Failure Acute 154 reports1.80%
Renal Failure Chronic 9 reports0.11%
Renal Impairment 38 reports0.44%
Renal Tubular Necrosis 21 reports0.25%
Respiratory Arrest 13 reports0.15%
Respiratory Failure 15 reports0.18%
Respiratory Rate Increased 9 reports0.11%
Retinal Detachment 11 reports0.13%
Rhabdomyolysis 23 reports0.27%
Rheumatoid Arthritis 16 reports0.19%
Scar 15 reports0.18%
Sepsis 29 reports0.34%
Septic Shock 13 reports0.15%
Shock 13 reports0.15%
Skin Discolouration 9 reports0.11%
Skin Exfoliation 14 reports0.16%
Skin Graft 8 reports0.09%
Skin Lesion 8 reports0.09%
Skin Necrosis 14 reports0.16%
Skin Ulcer 9 reports0.11%
Small Intestinal Stenosis 16 reports0.19%
Small Intestine Ulcer 9 reports0.11%
Somnolence 24 reports0.28%
Speech Disorder 9 reports0.11%
Stevens-johnson Syndrome 10 reports0.12%
Suicidal Ideation 16 reports0.19%
Suicide Attempt 13 reports0.15%
Surgery 13 reports0.15%
Swelling 19 reports0.22%
Swelling Face 26 reports0.30%
Swollen Tongue 16 reports0.19%
Syncope 28 reports0.33%
Tachycardia 23 reports0.27%
Therapeutic Agent Toxicity 9 reports0.11%
Thrombocytopenia 11 reports0.13%
Toxic Epidermal Necrolysis 15 reports0.18%
Toxicity To Various Agents 16 reports0.19%
Transient Ischaemic Attack 11 reports0.13%
Tremor 11 reports0.13%
Tubulointerstitial Nephritis 16 reports0.19%
Ulcer 13 reports0.15%
Upper Gastrointestinal Haemorrhage 21 reports0.25%
Urinary Retention 11 reports0.13%
Urinary Tract Infection 10 reports0.12%
Urine Output Decreased 10 reports0.12%
Urticaria 43 reports0.50%
Vision Blurred 13 reports0.15%
Visual Acuity Reduced 17 reports0.20%
Vitreous Haemorrhage 15 reports0.18%
Vomiting 127 reports1.48%
Weight Decreased 41 reports0.48%
Weight Increased 14 reports0.16%
Wheezing 12 reports0.14%
White Blood Cell Count Decreased 11 reports0.13%
White Blood Cell Count Increased 12 reports0.14%
Wound Haemorrhage 8 reports0.09%
Wound Secretion 9 reports0.11%

Displaying 400 Diclofenac side effects


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