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Epalrestat Gastrointestinal Haemorrhage Side Effects

Epalrestat Gastrointestinal Haemorrhage Side Effect Reports


The following Epalrestat Gastrointestinal Haemorrhage side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Gastrointestinal Haemorrhage, can occur, and what you can do about them.

A side effect could appear soon after you start Epalrestat or it might take time to develop.



Septic Shock, Melaena, Coagulopathy, Disseminated Intravascular Coagulation, Shock Haemorrhagic, Necrotising Colitis, Gastrointestinal Haemorrhage

This Gastrointestinal Haemorrhage side effect was reported by a physician from JAPAN. A patient (weight:NA) experienced the following symptoms/conditions: diabetic neuropathy,diabetes mellitus,hyperlipidaemia,atrial fibrillation,hyperuricaemia,hypertension. The patient was prescribed Epalrestat (dosage: 150 Mg), which was started on Apr 13, 2011. Concurrently used drugs:
  • Nesina (25 Mg)
  • Lipidil (200 Mg)
  • Pradaxa (300 Mg)
  • Allopurinol (100 Mg)
  • Losartan Potassium And Hydrochlorothiazide
  • Pradaxa (300 Mg)
  • Miglitol (150 Mg)
  • Rozerem (8 Mg)
When starting to take Epalrestat the consumer reported the following symptoms:
  • Septic Shock
  • Melaena
  • Coagulopathy
  • Disseminated Intravascular Coagulation
  • Shock Haemorrhagic
  • Necrotising Colitis
  • Gastrointestinal Haemorrhage
The patient was hospitalized and became disabled. These side effects may potentially be related to Epalrestat.
Gastrointestinal Haemorrhage, Septic Shock, Necrotising Colitis

This Gastrointestinal Haemorrhage Epalrestat side effect was reported by a physician from JAPAN on Sep 14, 2011. A male , weighting 162.0 lb, was diagnosed with and was treated with Epalrestat. The patient presented the following health conditions:
  • Gastrointestinal Haemorrhage
  • Septic Shock
  • Necrotising Colitis
. Epalrestat dosage: 150 Mg. Additional drugs used at the same time:
  • Lipidil (200 Mg)
  • Allopurinol (100 Mg)
  • Losartan Potassium And Hydrochlorothiazide
  • Pradaxa (300 Mg)
  • Pradaxa (300 Mg)
  • Nesina (25 Mg)
  • Miglitol (150 Mg)
  • Rozerem (80 Mg)

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Epalrestat Gastrointestinal Haemorrhage Causes and Reviews


Your digestive or gastrointestinal (GI) tract includes the esophagus, stomach, small intestine, large intestine or colon, rectum, and anus. Bleeding can come from any of these areas. The amount of bleeding can be so small that only a lab test can find it.

Signs of bleeding in the digestive tract depend where it is and how much bleeding there is.

Signs of bleeding in the upper digestive tract include

  • Bright red blood in vomit
  • Vomit that looks like coffee grounds
  • Black or tarry stool
  • Dark blood mixed with stool

Signs of bleeding in the lower digestive tract include

  • Black or tarry stool
  • Dark blood mixed with stool
  • Stool mixed or coated with bright red blood

GI bleeding is not a disease, but a symptom of a disease. There are many possible causes of GI bleeding, including hemorrhoids, peptic ulcers, tears or inflammation in the esophagus, diverticulosis and diverticulitis, ulcerative colitis and Crohn's disease, colonic polyps, or cancer in the colon, stomach or esophagus.

The test used most often to look for the cause of GI bleeding is called endoscopy. It uses a flexible instrument inserted through the mouth or rectum to view the inside of the GI tract. A type of endoscopy called colonoscopy looks at the large intestine.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


Epalrestat Gastrointestinal Haemorrhage Reviews

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Top Epalrestat Side Effects

Gastrointestinal Haemorrhage (3)
Septic Shock (2)
Coagulopathy (2)
Necrotising Colitis (2)
Shock Haemorrhagic (1)
Disseminated Intravascular Coagulation (1)
Melaena (1)

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