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Epalrestat Septic Shock Side Effects

Epalrestat Septic Shock Side Effect Reports


The following Epalrestat Septic Shock side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Septic Shock, can occur, and what you can do about them.

A side effect could appear soon after you start Epalrestat or it might take time to develop.



Septic Shock, Melaena, Coagulopathy, Disseminated Intravascular Coagulation, Shock Haemorrhagic, Necrotising Colitis, Gastrointestinal Haemorrhage

This Septic Shock side effect was reported by a physician from JAPAN. A patient (weight:NA) experienced the following symptoms/conditions: diabetic neuropathy,diabetes mellitus,hyperlipidaemia,atrial fibrillation,hyperuricaemia,hypertension. The patient was prescribed Epalrestat (dosage: 150 Mg), which was started on Apr 13, 2011. Concurrently used drugs:
  • Nesina (25 Mg)
  • Lipidil (200 Mg)
  • Pradaxa (300 Mg)
  • Allopurinol (100 Mg)
  • Losartan Potassium And Hydrochlorothiazide
  • Pradaxa (300 Mg)
  • Miglitol (150 Mg)
  • Rozerem (8 Mg)
When starting to take Epalrestat the consumer reported the following symptoms:
  • Septic Shock
  • Melaena
  • Coagulopathy
  • Disseminated Intravascular Coagulation
  • Shock Haemorrhagic
  • Necrotising Colitis
  • Gastrointestinal Haemorrhage
The patient was hospitalized and became disabled. These side effects may potentially be related to Epalrestat.
Gastrointestinal Haemorrhage, Septic Shock, Necrotising Colitis

This Septic Shock Epalrestat side effect was reported by a physician from JAPAN on Sep 14, 2011. A male , weighting 162.0 lb, was diagnosed with and was treated with Epalrestat. The patient presented the following health conditions:
  • Gastrointestinal Haemorrhage
  • Septic Shock
  • Necrotising Colitis
. Epalrestat dosage: 150 Mg. Additional drugs used at the same time:
  • Lipidil (200 Mg)
  • Allopurinol (100 Mg)
  • Losartan Potassium And Hydrochlorothiazide
  • Pradaxa (300 Mg)
  • Pradaxa (300 Mg)
  • Nesina (25 Mg)
  • Miglitol (150 Mg)
  • Rozerem (80 Mg)

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Epalrestat Septic Shock Causes and Reviews


Sepsis is a serious illness. It happens when your body has an overwhelming immune response to a bacterial infection. The chemicals released into the blood to fight the infection trigger widespread inflammation. This leads to blood clots and leaky blood vessels. They cause poor blood flow, which deprives your body's organs of nutrients and oxygen. In severe cases, one or more organs fail. In the worst cases, blood pressure drops and the heart weakens, leading to septic shock.

Anyone can get sepsis, but the risk is higher in

  • People with weakened immune systems
  • Infants and children
  • The elderly
  • People with chronic illnesses, such as diabetes, AIDS, cancer, and kidney or liver disease
  • People suffering from a severe burn or physical trauma

Common symptoms of sepsis are fever, chills, rapid breathing and heart rate, rash, confusion, and disorientation. Doctors diagnose sepsis using a blood test to see if the number of white blood cells is abnormal. They also do lab tests that check for signs of infection.

People with sepsis are usually treated in hospital intensive care units. Doctors try to treat the infection, sustain the vital organs, and prevent a drop in blood pressure. Many patients receive oxygen and intravenous (IV) fluids. Other types of treatment, such as respirators or kidney dialysis, may be necessary. Sometimes, surgery is needed to clear up an infection.

NIH: National Institute of General Medical Sciences


Epalrestat Septic Shock Reviews

No reviews submitted yet, check in later.

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Top Epalrestat Side Effects

Gastrointestinal Haemorrhage (3)
Septic Shock (2)
Coagulopathy (2)
Necrotising Colitis (2)
Shock Haemorrhagic (1)
Disseminated Intravascular Coagulation (1)
Melaena (1)

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