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Fluorouracil Confusional State Side Effects

Fluorouracil Confusional State Side Effect Reports


The following Fluorouracil Confusional State side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Confusional State, can occur, and what you can do about them.

A side effect could appear soon after you start Fluorouracil or it might take time to develop.



Agitation, Confusional State, Disorientation, Thrombocytopenia

This Confusional State side effect was reported by a consumer or non-health professional from US. A 68-year-old patient (weight:NA) experienced the following symptoms/conditions: squamous cell carcinoma of the oral cavity. The patient was prescribed Fluorouracil (dosage: NA), which was started on Jan 21, 2014. Concurrently used drugs:
  • Carboplatin
  • Erbitux
  • Lovenox
  • Lovenox
  • Valproate Sodium
  • Esomeprazole Magnesium
  • Kardegic
  • Durogesic
When starting to take Fluorouracil the consumer reported the following symptoms:
  • Agitation
  • Confusional State
  • Disorientation
  • Thrombocytopenia
The patient was hospitalized. These side effects may potentially be related to Fluorouracil.
Diabetic Hyperosmolar Coma, Confusional State, Malaise

This Confusional State Fluorouracil side effect was reported by a physician from JP on Nov 27, 2013. A male , 73 years of age, weighting 131.8 lb, was diagnosed with and was treated with Fluorouracil. The patient presented the following health conditions:
  • Diabetic Hyperosmolar Coma
  • Confusional State
  • Malaise
. Fluorouracil dosage: 700 Mg/body Mass Index, Per Day On Days 1-4 And 29-32. Additional drugs used at the same time:
  • Cisplatin (70 Mg/m2/day, On Day 1 And 29)
  • Dexamethasone (6.6 Mg, On Infusion Days)
  • Dexamethasone (8 Mg, On Three Subsequent Days)
The patient was hospitalized.
Restlessness, Weight Decreased, Confusional State

This is a Fluorouracil side effect report of a 62-year-old patient (weight:NA) from GB, suffering from the following symptoms/conditions: pancreatic carcinoma, who was treated with Fluorouracil (dosage:6600 Mg, 14 Days, Intravenous (not Otherwise Specified), start time: Mar 18, 2013), combined with:
  • Irinotecan
  • Oxaliplatin (200 Mg, 14 Days, Intravenous (not Otherwise Specified))
  • Ethanol (ethanol)
  • Citalopram (citalopram)
  • Codeine Phosphate (codeine Phosphate)
  • Alpha Amylase (alpha-amylase Swine Pancreas)
  • Amylase (amylase)
  • Lipase (lipase)
, and developed a serious reaction and a Confusional State side effect. The patient presented with:
  • Restlessness
  • Weight Decreased
  • Confusional State
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Fluorouracil treatment in patients suffering from pancreatic carcinoma, resulting in Confusional State.

Syncope, Encephalopathy, Myocardial Infarction, Urinary Tract Infection, Cerebrovascular Accident, Confusional State, Agitation

A 79-year-old female patient (weight: NA) from US with the following symptoms: colon cancer started Fluorouracil treatment (dosage: (not Otherwise Specified)?) on Sep 18, 2012. Soon after starting Fluorouracil treatment, the consumer experienced several side effects, including:
  • Syncope
  • Encephalopathy
  • Myocardial Infarction
  • Urinary Tract Infection
  • Cerebrovascular Accident
  • Confusional State
  • Agitation
. Concurrently used drugs:
  • Oxaliplatin (Intravenous (otherwise Not Specified)??)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Fluorouracil side effects, such as Confusional State.
Hyperammonaemic Encephalopathy, Renal Failure Acute, Nausea, Vomiting, Altered State Of Consciousness, Confusional State, Somnolence, Lethargy, Dysarthria

A patient from TW was prescribed and started Fluorouracil on Feb 19, 2013. Patient felt the following Fluorouracil side effects: hyperammonaemic encephalopathy, renal failure acute, nausea, vomiting, altered state of consciousness, confusional state, somnolence, lethargy, dysarthria Additional patient health information: male , 58 years of age, The consumer reported the following symptoms: was diagnosed with and. Fluorouracil dosage: 1200 Mg/m2, Unk. Concurrently used drugs: NA. The patient was hospitalized.
Metabolic Encephalopathy, Hepatic Encephalopathy, Deep Vein Thrombosis, Neutropenia, Pneumonia Aspiration, Diarrhoea, Vomiting, Dehydration, Confusional State

This report suggests a potential Fluorouracil Confusional State side effect(s) that can have serious consequences. A 50-year-old patient from US (weight:NA) was diagnosed with the following health condition(s): hepatic neoplasm malignant recurrent and used Fluorouracil (dosage: 370 Mg/m2, On Days Two Through Five) starting NS. Soon after starting Fluorouracil the patient began experiencing various side effects, including:
  • Metabolic Encephalopathy
  • Hepatic Encephalopathy
  • Deep Vein Thrombosis
  • Neutropenia
  • Pneumonia Aspiration
  • Diarrhoea
  • Vomiting
  • Dehydration
  • Confusional State
Drugs used concurrently:NA. The patient was hospitalized. Although Fluorouracil demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Confusional State, may still occur.
Encephalopathy, Vomiting, Nausea, Incoherent, Ammonia Increased, Diarrhoea, Amnesia, Confusional State, Disorientation

An adverse event was reported by a physician on Apr 30, 2012 by a male taking Fluorouracil (dosage: 500 Mg/m2, Weekly) . Location: TURKEY , 59 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Fluorouracil side effects: encephalopathy, vomiting, nausea, incoherent, ammonia increased, diarrhoea, amnesia, confusional state, disorientation. Additional medications/treatments:
Associated medications used:
  • Leucovorin Calcium (150 Mg/m2, Unk)
  • Leucovorin Calcium (200 Mg/m2 As A 2 Hour Iv Infusion)
  • Stalevo 100 (3 Tablets, Qd)
The patient was hospitalized.
Confusional State

This Confusional State problem was reported by a health professional from GERMANY. A 70-year-old patient (weight: NA) was diagnosed with the following medical condition(s): head and neck cancer.On Apr 18, 2012 a consumer started treatment with Fluorouracil (dosage: NA). The following drugs/medications were being taken at the same time:
  • Docetaxel
  • Cisplatin
  • Cetuximab
When commencing Fluorouracil, the patient experienced the following unwanted symptoms /side effects:
  • Confusional State
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Confusional State, may become evident only after a product is in use by the general population.
Confusional State, Somnolence, Dysarthria, Thrombocytopenia, Neutropenia, Skin Toxicity, Mucosal Inflammation

This is a Fluorouracil side effect report of a 65-year-old female patient (weight: NA) from FR. The patient developed the following symptoms/conditions: colon cancer and was treated with Fluorouracil (dosage: Total Dose 6400mg) starting NS. Concurrently used drugs:
  • Folinic Acid
Soon after that, the consumer experienced the following of symptoms:
  • Confusional State
  • Somnolence
  • Dysarthria
  • Thrombocytopenia
  • Neutropenia
  • Skin Toxicity
  • Mucosal Inflammation
The patient was hospitalized. This opens a possibility that Fluorouracil could cause Confusional State and that some female patients may be more susceptible.
Hypokalaemia, Weight Decreased, Encephalopathy, Vomiting, Abdominal Pain, Confusional State, Dehydration, Neutropenia, Diarrhoea

This Confusional State side effect was reported by a health professional from FRANCE on Apr 13, 2012. A patient from FRANCE , 65 years of age, weighting 132.3 lb, was treated with Fluorouracil. Directly after treatment started, patient experienced the unwanted or unexpected Fluorouracil side effects: hypokalaemia, weight decreased, encephalopathy, vomiting, abdominal pain, confusional state, dehydration, neutropenia, diarrhoea. Fluorouracil dosage: 1670 Mg, 1x/day. The patient was hospitalized. These side effects may potentially be related to Fluorouracil.
Neurotoxicity, Dysarthria, Skin Toxicity, Frontotemporal Dementia, Mucosal Inflammation, Neutropenia, Confusional State, Thrombocytopenia, Somnolence

This Confusional State side effect was reported by a consumer or non-health professional from FRANCE. A 65-year-old female patient (weight:NA) experienced the following symptoms/conditions: colon cancer. The patient was prescribed Fluorouracil (dosage: 6400 Mg, Total), which was started on NS. Concurrently used drugs:
  • Folinic Acid (folinic Acid) (folinic Acid)
When starting to take Fluorouracil the consumer reported the following symptoms:
  • Neurotoxicity
  • Dysarthria
  • Skin Toxicity
  • Frontotemporal Dementia
  • Mucosal Inflammation
  • Neutropenia
  • Confusional State
  • Thrombocytopenia
  • Somnolence
These side effects may potentially be related to Fluorouracil.
Somnolence, Dysarthria, Thrombocytopenia, Neutropenia, Skin Toxicity, Mucosal Inflammation, Confusional State

This Confusional State Fluorouracil side effect was reported by a health professional from FRANCE on Dec 16, 2011. A Female , 65 years of age, was diagnosed with and was treated with Fluorouracil. The patient presented the following health conditions:
  • Somnolence
  • Dysarthria
  • Thrombocytopenia
  • Neutropenia
  • Skin Toxicity
  • Mucosal Inflammation
  • Confusional State
. Fluorouracil dosage: Total Dose 6400mg. Additional drugs used at the same time:
  • Leucovorin Calcium
The patient was hospitalized.
Confusional State, Pyrexia, Nausea, Neurological Decompensation, Air Embolism, Intracranial Pressure Increased, Grand Mal Convulsion, Gastrointestinal Toxicity, Brain Oedema

This is a Fluorouracil side effect report of a 38-year-old female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: NA, who was treated with Fluorouracil (dosage:Continuous Infusion, start time: NS), combined with:
  • Therapeutic Radiopharmaceuticals (50 Gy Given In 28 Fraction)
  • Oxaliplatin (2-hour Duration)
, and developed a serious reaction and a Confusional State side effect. The patient presented with:
  • Confusional State
  • Pyrexia
  • Nausea
  • Neurological Decompensation
  • Air Embolism
  • Intracranial Pressure Increased
  • Grand Mal Convulsion
  • Gastrointestinal Toxicity
  • Brain Oedema
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Fluorouracil treatment in female patients suffering from NA, resulting in Confusional State.
Posterior Reversible Encephalopathy Syndrome, Confusional State

A 63-year-old female patient (weight: NA) from AUSTRALIA with the following symptoms: NA started Fluorouracil treatment (dosage: 2400 Mg/m2, Cyclic (on Day 1 And 2 Every 14 Days)) on Aug 02, 2011. Soon after starting Fluorouracil treatment, the consumer experienced several side effects, including:
  • Posterior Reversible Encephalopathy Syndrome
  • Confusional State
. Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Fluorouracil side effects, such as Confusional State.
Leukoencephalopathy, Confusional State

A female patient from AUSTRALIA was prescribed and started Fluorouracil on Nov 08, 2011. After Fluorouracil was administered, patient encountered several Fluorouracil side effects: leukoencephalopathy, confusional state Additional patient health information: Female , 63 years of age, weighting 147.7 lb, The consumer reported the following symptoms: was diagnosed with and. Fluorouracil dosage: 400 Mg/m2, Cyclic (on Day 1 Every 14 Days). Concurrently used drugs:
  • Leucovorin Calcium (400 Mg/m2, Cyclic (on Day 1 Every 14 Days))
  • Metoclopramide Hydrochloride (Unk)
  • Irinotecan Hcl (180 Mg/m2, Cyclic (on Day 1 Every 14 Days))
The patient was hospitalized.
Confusional State, Leukoencephalopathy

This report suggests a potential Fluorouracil Confusional State side effect(s) that can have serious consequences. A 63-year-old female patient from AUSTRALIA (weight:NA) was diagnosed with the following health condition(s): NA and used Fluorouracil (dosage: 2400 Mg/m2, Cyclic (on Day 1 And 2 Every 14 Days)) starting Aug 02, 2011. Soon after starting Fluorouracil the patient began experiencing various side effects, including:
  • Confusional State
  • Leukoencephalopathy
Drugs used concurrently:
  • Haloperidol (Unk)
The patient was hospitalized. Although Fluorouracil demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Confusional State, may still occur.
Tremor, Vomiting, Convulsion, Encephalopathy, Confusional State, Hyperammonaemia

An adverse event was reported by a health professional on Oct 03, 2011 by a Female taking Fluorouracil (dosage: 2400 Mg/m2 (48-hr Infusion)) . Location: JAPAN , 74 years of age, patient began experiencing various side effects, including: Patient felt the following Fluorouracil side effects: tremor, vomiting, convulsion, encephalopathy, confusional state, hyperammonaemia. Additional medications/treatments: The patient was hospitalized.
Vomiting, Tremor, Hyperammonaemia, Confusional State, Convulsion, Encephalopathy

This Confusional State problem was reported by a health professional from JAPAN. A 74-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): colon cancer recurrent.On NS a consumer started treatment with Fluorouracil (dosage: 400 Mg/m2 (rapid Iv Injection On Day 1)). The following drugs/medications were being taken at the same time: NA. When commencing Fluorouracil, the patient experienced the following unwanted symptoms /side effects:
  • Vomiting
  • Tremor
  • Hyperammonaemia
  • Confusional State
  • Convulsion
  • Encephalopathy
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Confusional State, may become evident only after a product is in use by the general population.
Confusional State

This is a Fluorouracil side effect report of a 73-year-old female patient (weight: NA) from FRANCE. The patient developed the following symptoms/conditions: NA and was treated with Fluorouracil (dosage: 1500 Mg/m2 / Cycle Dose:50 Milligram(s)/millilitre) starting Jun 15, 2011. Concurrently used drugs:
  • Oxaliplatin (85 Mg/m2 / Cycle)
Soon after that, the consumer experienced the following of symptoms:
  • Confusional State
The patient was hospitalized. This opens a possibility that Fluorouracil could cause Confusional State and that some female patients may be more susceptible.
Speech Disorder, Anaemia, Pyrexia, Mental Impairment, Bedridden, Loss Of Consciousness, Eating Disorder, Confusional State

This Confusional State side effect was reported by a health professional from GREECE on Jul 19, 2011. A female patient from GREECE , 60 years of age, was diagnosed with and was treated with Fluorouracil. Patient felt the following Fluorouracil side effects: speech disorder, anaemia, pyrexia, mental impairment, bedridden, loss of consciousness, eating disorder, confusional state. Fluorouracil dosage: NA.
Multiple prescriptions taken:
  • Methotrexate (Unk Ukn, Unk)
  • Cyclophosphamide
  • Methotrexate (12 Mg Twice/week)
  • Tamoxifen Citrate
  • Methotrexate (Unk Ukn, Unk)
The patient was hospitalized. These side effects may potentially be related to Fluorouracil.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Fluorouracil Confusional State Causes and Reviews


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NIH: National Cancer Institute


Fluorouracil Confusional State Reviews

Wed, 28 May 2014

The side effects of Fluorouracil are most likely to be minor and temporary.InternationalDrugMart

Fri, 20 May 2011

its not 1%---more like 14% and that may even be a conservative estimate--Your doctor is lieing to you--surprised???

Sun, 13 Mar 2011

My fiancee passed away on 3/7/2011 after her second round of 5FU. The oncologist had used the words "surprised" and "out of the ordinary" on her reaction to the first round because of the amount and severity of her side effects. He still gave her the same dosage for the second round. Ten days later, she was in ICU. Seven days after going to the hospital, she was dead. She was 47 and in incredible shape except for the colon cancer. The doctor told us that she was part of the 1% of the population that didn't have the enzyme to metabolize the 5FU but she wasn't given the test because of the low percentage. With that decision, the woman I loved is no longer here.Her name was Birgit.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Fluorouracil Side Effects

Diarrhoea (463)
Nausea (335)
Dehydration (273)
Vomiting (266)
Neutropenia (243)
Febrile Neutropenia (207)
Pyrexia (187)
Mucosal Inflammation (179)
Asthenia (158)
Abdominal Pain (152)
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Fatigue (134)
Dyspnoea (131)
Interstitial Lung Disease (117)
Decreased Appetite (116)
Pulmonary Embolism (111)
Chest Pain (110)
Anaemia (106)
Thrombocytopenia (106)
Hypotension (106)
Neutrophil Count Decreased (99)
Hypokalaemia (95)
Leukopenia (83)
Sepsis (78)
White Blood Cell Count Decreased (78)
Renal Failure Acute (75)
Pneumonia (75)
Malaise (74)
Haemoglobin Decreased (72)
Neuropathy Peripheral (69)
Pain (69)
Renal Failure (64)
Disease Progression (64)
Respiratory Failure (62)
Cardiotoxicity (62)
Dysphagia (61)
Confusional State (57)
Platelet Count Decreased (57)
Pancytopenia (55)
Fall (55)
Deep Vein Thrombosis (54)
Myocardial Infarction (53)
Arteriospasm Coronary (51)
Hyponatraemia (51)
Weight Decreased (51)
Tachycardia (48)
Chills (46)
Dizziness (46)
Septic Shock (46)
Hyperammonaemia (46)

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