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Fluorouracil Side Effects List

Common Fluorouracil Side Effects


The following Fluorouracil Side Effects were reported by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers) and manufacturers.

It is important to know potential risks posed by drugs and health products. Staying informed can help you make right decisions and stay healthy.

You can read detailed reports by clicking on a side effect.




Abdominal Discomfort 18 reports0.16%
Abdominal Distension 14 reports0.13%
Abdominal Pain 151 reports1.35%
Abdominal Pain Lower 7 reports0.06%
Abdominal Pain Upper 39 reports0.35%
Abdominal Tenderness 7 reports0.06%
Abscess 8 reports0.07%
Acidosis 11 reports0.10%
Acne 9 reports0.08%
Acute Coronary Syndrome 18 reports0.16%
Acute Myeloid Leukaemia 31 reports0.28%
Acute Myocardial Infarction 36 reports0.32%
Acute Promyelocytic Leukaemia 10 reports0.09%
Acute Respiratory Distress Syndrome 17 reports0.15%
Acute Respiratory Failure 9 reports0.08%
Agitation 10 reports0.09%
Agranulocytosis 8 reports0.07%
Alanine Aminotransferase Increased 19 reports0.17%
Alopecia 42 reports0.38%
Altered State Of Consciousness 30 reports0.27%
Amnesia 8 reports0.07%
Anaemia 106 reports0.95%
Anaphylactic Shock 9 reports0.08%
Angina Pectoris 27 reports0.24%
Angioedema 8 reports0.07%
Anorectal Discomfort 9 reports0.08%
Anorexia 30 reports0.27%
Anxiety 7 reports0.06%
Aortic Thrombosis 11 reports0.10%
Aorto-oesophageal Fistula 12 reports0.11%
Aphasia 12 reports0.11%
Aphthous Stomatitis 7 reports0.06%
Apicectomy 7 reports0.06%
Application Site Erythema 7 reports0.06%
Arrhythmia 14 reports0.13%
Arteriospasm Coronary 51 reports0.46%
Arthralgia 25 reports0.22%
Ascites 24 reports0.21%
Aspartate Aminotransferase Increased 24 reports0.21%
Aspiration 8 reports0.07%
Asthenia 158 reports1.41%
Asthma 8 reports0.07%
Atelectasis 17 reports0.15%
Atrial Fibrillation 45 reports0.40%
Back Pain 19 reports0.17%
Bacteraemia 12 reports0.11%
Bacterial Infection 19 reports0.17%
Bacterial Sepsis 9 reports0.08%
Balance Disorder 9 reports0.08%
Blood Albumin Decreased 12 reports0.11%
Blood Alkaline Phosphatase Increased 21 reports0.19%
Blood Bilirubin Increased 28 reports0.25%
Blood Calcium Decreased 13 reports0.12%
Blood Chloride Increased 7 reports0.06%
Blood Creatine Phosphokinase Increased 10 reports0.09%
Blood Creatinine Increased 42 reports0.38%
Blood Culture Positive 28 reports0.25%
Blood Glucose Increased 19 reports0.17%
Blood Lactate Dehydrogenase Increased 8 reports0.07%
Blood Magnesium Decreased 11 reports0.10%
Blood Phosphorus Decreased 7 reports0.06%
Blood Potassium Decreased 39 reports0.35%
Blood Pressure Decreased 22 reports0.20%
Blood Pressure Increased 24 reports0.21%
Blood Pressure Systolic Decreased 7 reports0.06%
Blood Sodium Decreased 23 reports0.21%
Blood Urea Increased 18 reports0.16%
Body Temperature Increased 28 reports0.25%
Bone Disorder 12 reports0.11%
Bone Graft 7 reports0.06%
Bone Marrow Failure 45 reports0.40%
Bone Pain 15 reports0.13%
Bradycardia 9 reports0.08%
Bronchitis 17 reports0.15%
Bronchopneumonia 7 reports0.06%
Burning Sensation 11 reports0.10%
C-reactive Protein Increased 25 reports0.22%
Cachexia 10 reports0.09%
Candidiasis 13 reports0.12%
Cardiac Arrest 46 reports0.41%
Cardiac Disorder 8 reports0.07%
Cardiac Failure 31 reports0.28%
Cardiac Failure Acute 11 reports0.10%
Cardiac Failure Congestive 12 reports0.11%
Cardio-respiratory Arrest 19 reports0.17%
Cardiogenic Shock 15 reports0.13%
Cardiomyopathy 17 reports0.15%
Cardiotoxicity 62 reports0.55%
Catheter Related Infection 18 reports0.16%
Cellulitis 18 reports0.16%
Cerebral Haemorrhage 11 reports0.10%
Cerebral Infarction 23 reports0.21%
Cerebral Ischaemia 7 reports0.06%
Cerebrovascular Accident 21 reports0.19%
Chest Discomfort 10 reports0.09%
Chest Pain 109 reports0.98%
Chills 46 reports0.41%
Cholangitis 12 reports0.11%
Cholecystitis 10 reports0.09%
Cholecystitis Acute 8 reports0.07%
Cholestasis 7 reports0.06%
Chronic Myeloid Leukaemia 7 reports0.06%
Circulatory Collapse 11 reports0.10%
Clostridial Infection 11 reports0.10%
Clostridium Difficile Colitis 12 reports0.11%
Cognitive Disorder 14 reports0.13%
Colitis 23 reports0.21%
Colitis Ischaemic 7 reports0.06%
Colon Cancer 11 reports0.10%
Colon Cancer Metastatic 13 reports0.12%
Colorectal Cancer 31 reports0.28%
Colorectal Cancer Metastatic 8 reports0.07%
Coma 21 reports0.19%
Condition Aggravated 29 reports0.26%
Confusional State 57 reports0.51%
Congestive Cardiomyopathy 9 reports0.08%
Conjunctivitis 8 reports0.07%
Constipation 41 reports0.37%
Contusion 7 reports0.06%
Convulsion 33 reports0.30%
Coronary Artery Disease 8 reports0.07%
Coronary Artery Stenosis 11 reports0.10%
Cough 29 reports0.26%
Culture Urine Positive 12 reports0.11%
Cutaneous Lupus Erythematosus 8 reports0.07%
Death 39 reports0.35%
Decreased Appetite 116 reports1.04%
Deep Vein Thrombosis 54 reports0.48%
Dehydration 273 reports2.44%
Depressed Level Of Consciousness 29 reports0.26%
Depression 14 reports0.13%
Dermatitis 18 reports0.16%
Dermatitis Acneiform 37 reports0.33%
Device Related Infection 12 reports0.11%
Diarrhoea 462 reports4.13%
Diarrhoea Haemorrhagic 9 reports0.08%
Diffuse Alveolar Damage 10 reports0.09%
Dihydropyrimidine Dehydrogenase Deficiency 9 reports0.08%
Disease Progression 64 reports0.57%
Disease Recurrence 9 reports0.08%
Disorientation 11 reports0.10%
Disseminated Intravascular Coagulation 26 reports0.23%
Diverticulitis 11 reports0.10%
Dizziness 46 reports0.41%
Dry Mouth 8 reports0.07%
Dry Skin 13 reports0.12%
Duodenal Ulcer Haemorrhage 8 reports0.07%
Dysarthria 32 reports0.29%
Dyspepsia 10 reports0.09%
Dysphagia 61 reports0.55%
Dysphonia 13 reports0.12%
Dyspnoea 131 reports1.17%
Dyspnoea Exertional 15 reports0.13%
Dysuria 16 reports0.14%
Ejection Fraction Decreased 33 reports0.30%
Electrocardiogram Qt Prolonged 7 reports0.06%
Electrocardiogram St Segment Depression 7 reports0.06%
Electrocardiogram St Segment Elevation 28 reports0.25%
Electrocardiogram T Wave Abnormal 8 reports0.07%
Electrocardiogram T Wave Inversion 8 reports0.07%
Electrolyte Imbalance 14 reports0.13%
Encephalopathy 42 reports0.38%
Enteritis 15 reports0.13%
Enterocolitis 10 reports0.09%
Epistaxis 15 reports0.13%
Erythema 37 reports0.33%
Escherichia Infection 10 reports0.09%
Fall 55 reports0.49%
Fatigue 134 reports1.20%
Febrile Bone Marrow Aplasia 8 reports0.07%
Febrile Neutropenia 207 reports1.85%
Feeling Abnormal 11 reports0.10%
Fistula 9 reports0.08%
Flushing 7 reports0.06%
Fungal Infection 9 reports0.08%
Gait Disturbance 21 reports0.19%
Gastric Cancer 7 reports0.06%
Gastric Ulcer 7 reports0.06%
Gastritis 10 reports0.09%
Gastroenteritis 9 reports0.08%
Gastroenteritis Radiation 7 reports0.06%
Gastrointestinal Disorder 14 reports0.13%
Gastrointestinal Haemorrhage 36 reports0.32%
Gastrointestinal Inflammation 8 reports0.07%
Gastrointestinal Perforation 18 reports0.16%
Gastrointestinal Toxicity 13 reports0.12%
Gastrooesophageal Reflux Disease 8 reports0.07%
Grand Mal Convulsion 25 reports0.22%
Granulocytopenia 7 reports0.06%
Haematemesis 13 reports0.12%
Haematochezia 9 reports0.08%
Haematocrit Decreased 22 reports0.20%
Haematotoxicity 13 reports0.12%
Haematuria 13 reports0.12%
Haemodialysis 17 reports0.15%
Haemoglobin Abnormal 12 reports0.11%
Haemoglobin Decreased 72 reports0.64%
Haemolysis 12 reports0.11%
Haemolytic Uraemic Syndrome 7 reports0.06%
Haemoptysis 12 reports0.11%
Haemorrhage 32 reports0.29%
Headache 39 reports0.35%
Heart Rate Increased 17 reports0.15%
Hemiparesis 11 reports0.10%
Hepatic Failure 19 reports0.17%
Hepatic Function Abnormal 8 reports0.07%
Hepatic Steatosis 16 reports0.14%
Hepatitis B 10 reports0.09%
Hepatocellular Injury 7 reports0.06%
Hepatotoxicity 8 reports0.07%
Hiccups 8 reports0.07%
Hot Flush 7 reports0.06%
Hydronephrosis 12 reports0.11%
Hyperammonaemia 46 reports0.41%
Hyperammonaemic Encephalopathy 32 reports0.29%
Hyperbilirubinaemia 14 reports0.13%
Hyperglycaemia 11 reports0.10%
Hyperhidrosis 23 reports0.21%
Hyperkalaemia 8 reports0.07%
Hyperpyrexia 9 reports0.08%
Hypersensitivity 24 reports0.21%
Hypertension 45 reports0.40%
Hypoaesthesia 31 reports0.28%
Hypocalcaemia 15 reports0.13%
Hypoglycaemia 12 reports0.11%
Hypokalaemia 95 reports0.85%
Hypokinesia 7 reports0.06%
Hypomagnesaemia 24 reports0.21%
Hyponatraemia 51 reports0.46%
Hypophagia 36 reports0.32%
Hypotension 106 reports0.95%
Hypovolaemia 25 reports0.22%
Hypoxia 25 reports0.22%
Ileus 31 reports0.28%
Ileus Paralytic 8 reports0.07%
Impaired Healing 11 reports0.10%
Incorrect Dose Administered 8 reports0.07%
Infection 35 reports0.31%
Infectious Peritonitis 7 reports0.06%
Infusion Related Reaction 22 reports0.20%
Insomnia 11 reports0.10%
International Normalised Ratio Increased 13 reports0.12%
Interstitial Lung Disease 117 reports1.05%
Intestinal Ischaemia 10 reports0.09%
Intestinal Obstruction 31 reports0.28%
Intestinal Perforation 21 reports0.19%
Ischaemic Stroke 12 reports0.11%
Jaundice 14 reports0.13%
Lacrimation Increased 8 reports0.07%
Large Intestine Perforation 17 reports0.15%
Laryngospasm 8 reports0.07%
Left Ventricular Dysfunction 19 reports0.17%
Lethargy 16 reports0.14%
Leukocytosis 20 reports0.18%
Leukoencephalopathy 35 reports0.31%
Leukopenia 83 reports0.74%
Liver Disorder 11 reports0.10%
Liver Function Test Abnormal 22 reports0.20%
Lobar Pneumonia 7 reports0.06%
Loss Of Consciousness 41 reports0.37%
Lung Disorder 10 reports0.09%
Lung Infection 9 reports0.08%
Lung Infiltration 11 reports0.10%
Malaise 74 reports0.66%
Malignant Neoplasm Progression 25 reports0.22%
Malnutrition 10 reports0.09%
Melaena 12 reports0.11%
Mental Status Changes 17 reports0.15%
Metabolic Acidosis 20 reports0.18%
Metastases To Liver 15 reports0.13%
Metastases To Lung 12 reports0.11%
Mucosal Inflammation 179 reports1.60%
Multi-organ Failure 30 reports0.27%
Muscle Spasms 10 reports0.09%
Muscular Weakness 11 reports0.10%
Musculoskeletal Pain 7 reports0.06%
Myalgia 7 reports0.06%
Myelodysplastic Syndrome 9 reports0.08%
Myocardial Infarction 53 reports0.47%
Myocardial Ischaemia 21 reports0.19%
Myocarditis 10 reports0.09%
Myopericarditis 7 reports0.06%
Nausea 335 reports3.00%
Neoplasm Malignant 30 reports0.27%
Neoplasm Progression 17 reports0.15%
Nervous System Disorder 7 reports0.06%
Neuropathy 8 reports0.07%
Neuropathy Peripheral 69 reports0.62%
Neurotoxicity 25 reports0.22%
Neutropenia 243 reports2.17%
Neutropenic Sepsis 26 reports0.23%
Neutrophil Count Abnormal 11 reports0.10%
Neutrophil Count Decreased 99 reports0.89%
No Therapeutic Response 16 reports0.14%
Odynophagia 12 reports0.11%
Oedema 13 reports0.12%
Oedema Peripheral 20 reports0.18%
Oesophageal Fistula 24 reports0.21%
Oesophagitis 17 reports0.15%
Off Label Use 18 reports0.16%
Oliguria 8 reports0.07%
Oral Candidiasis 12 reports0.11%
Oral Intake Reduced 29 reports0.26%
Oral Pain 19 reports0.17%
Organising Pneumonia 7 reports0.06%
Oropharyngeal Pain 7 reports0.06%
Orthostatic Hypotension 10 reports0.09%
Overdose 7 reports0.06%
Oxygen Saturation Decreased 10 reports0.09%
Pain 69 reports0.62%
Pain In Extremity 22 reports0.20%
Palmar-plantar Erythrodysaesthesia Syndrome 37 reports0.33%
Palpitations 20 reports0.18%
Pancreatitis 10 reports0.09%
Pancreatitis Acute 8 reports0.07%
Pancytopenia 55 reports0.49%
Paraesthesia 34 reports0.30%
Paronychia 19 reports0.17%
Performance Status Decreased 7 reports0.06%
Pericarditis 7 reports0.06%
Peripheral Ischaemia 12 reports0.11%
Peripheral Sensory Neuropathy 20 reports0.18%
Peritonitis 23 reports0.21%
Pharyngolaryngeal Pain 9 reports0.08%
Platelet Count Abnormal 8 reports0.07%
Platelet Count Decreased 57 reports0.51%
Pleural Effusion 24 reports0.21%
Pleuritic Pain 8 reports0.07%
Pneumonia 75 reports0.67%
Pneumonia Aspiration 9 reports0.08%
Polyneuropathy 8 reports0.07%
Portal Hypertension 10 reports0.09%
Post Procedural Complication 12 reports0.11%
Posterior Reversible Encephalopathy Syndrome 21 reports0.19%
Proctalgia 14 reports0.13%
Proteinuria 8 reports0.07%
Pruritus 23 reports0.21%
Pseudomembranous Colitis 11 reports0.10%
Pulmonary Embolism 111 reports0.99%
Pulmonary Fibrosis 34 reports0.30%
Pulmonary Oedema 13 reports0.12%
Pulse Absent 9 reports0.08%
Pyrexia 187 reports1.67%
Radiation Injury 8 reports0.07%
Radiation Skin Injury 23 reports0.21%
Rales 8 reports0.07%
Rash 37 reports0.33%
Rash Erythematous 8 reports0.07%
Rectal Haemorrhage 15 reports0.13%
Renal Failure 64 reports0.57%
Renal Failure Acute 75 reports0.67%
Renal Impairment 18 reports0.16%
Respiratory Distress 14 reports0.13%
Respiratory Failure 62 reports0.55%
Restlessness 8 reports0.07%
Reversible Posterior Leukoencephalopathy Syndrome 13 reports0.12%
Scab 8 reports0.07%
Sepsis 78 reports0.70%
Septic Shock 46 reports0.41%
Shock 16 reports0.14%
Sinus Bradycardia 10 reports0.09%
Sinus Tachycardia 14 reports0.13%
Skin Disorder 10 reports0.09%
Skin Exfoliation 17 reports0.15%
Skin Toxicity 14 reports0.13%
Skin Ulcer 10 reports0.09%
Small Intestinal Obstruction 25 reports0.22%
Somnolence 18 reports0.16%
Speech Disorder 9 reports0.08%
Splenomegaly 21 reports0.19%
Staphylococcal Infection 18 reports0.16%
Status Epilepticus 10 reports0.09%
Stomatitis 143 reports1.28%
Stress Cardiomyopathy 36 reports0.32%
Subileus 9 reports0.08%
Sudden Death 12 reports0.11%
Supraventricular Tachycardia 15 reports0.13%
Syncope 44 reports0.39%
Tachycardia 48 reports0.43%
Thrombocytopenia 106 reports0.95%
Thrombosis 16 reports0.14%
Toxicity To Various Agents 38 reports0.34%
Transient Ischaemic Attack 9 reports0.08%
Tremor 19 reports0.17%
Troponin Increased 10 reports0.09%
Tumour Haemorrhage 8 reports0.07%
Tumour Lysis Syndrome 8 reports0.07%
Unresponsive To Stimuli 11 reports0.10%
Urinary Retention 10 reports0.09%
Urinary Tract Infection 40 reports0.36%
Urticaria 11 reports0.10%
Ventricular Fibrillation 23 reports0.21%
Ventricular Tachycardia 19 reports0.17%
Vision Blurred 8 reports0.07%
Visual Impairment 12 reports0.11%
Vomiting 266 reports2.38%
Weight Decreased 51 reports0.46%
White Blood Cell Count Abnormal 11 reports0.10%
White Blood Cell Count Decreased 78 reports0.70%
White Blood Cell Count Increased 14 reports0.13%

Displaying 400 Fluorouracil side effects


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