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Fluorouracil Pain Side Effects

Fluorouracil Pain Side Effect Reports


The following Fluorouracil Pain side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Pain, can occur, and what you can do about them.

A side effect could appear soon after you start Fluorouracil or it might take time to develop.



Pancytopenia, Mucosal Inflammation, Dehydration, Clostridium Difficile Infection, Large Intestine Perforation, Peritonitis, Pain

This Pain side effect was reported by a physician from US. A 60-year-old female patient (weight:NA) experienced the following symptoms/conditions: colon cancer metastatic. The patient was prescribed Fluorouracil (dosage: NA), which was started on NS. Concurrently used drugs:
  • Folinic Acid
  • Oxaliplatin
When starting to take Fluorouracil the consumer reported the following symptoms:
  • Pancytopenia
  • Mucosal Inflammation
  • Dehydration
  • Clostridium Difficile Infection
  • Large Intestine Perforation
  • Peritonitis
  • Pain
The patient was hospitalized. These side effects may potentially be related to Fluorouracil.
Mucosal Inflammation, Oesophagitis, Pain, Dehydration, Pancytopenia, Clostridium Difficile Infection, Large Intestine Perforation, Peritonitis, Factor Vii Deficiency

This Pain Fluorouracil side effect was reported by a physician from US on Jan 21, 2014. A Female , 60 years of age, was diagnosed with and was treated with Fluorouracil. The patient presented the following health conditions:
  • Mucosal Inflammation
  • Oesophagitis
  • Pain
  • Dehydration
  • Pancytopenia
  • Clostridium Difficile Infection
  • Large Intestine Perforation
  • Peritonitis
  • Factor Vii Deficiency
. Fluorouracil dosage: 400 Mg/m2, Single Push. Additional drugs used at the same time: NA. The patient was hospitalized.
Pancytopenia, Mucosal Inflammation, Oesophagitis, Pain, Dehydration, Clostridium Difficile Infection, Large Intestine Perforation, Peritonitis, Delirium

This is a Fluorouracil side effect report of a 60-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: colon cancer metastatic, who was treated with Fluorouracil (dosage:400 Mg/m2, Iv Push, start time: NS), combined with: NA., and developed a serious reaction and a Pain side effect. The patient presented with:
  • Pancytopenia
  • Mucosal Inflammation
  • Oesophagitis
  • Pain
  • Dehydration
  • Clostridium Difficile Infection
  • Large Intestine Perforation
  • Peritonitis
  • Delirium
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Fluorouracil treatment in female patients suffering from colon cancer metastatic, resulting in Pain.

Herpes Zoster, Pain

A 72-year-old female patient (weight: NA) from US with the following symptoms: precancerous cells present started Fluorouracil treatment (dosage: Apply 2x 2x Daily 3 Weeks) on Oct 21, 2013. Soon after starting Fluorouracil treatment, the consumer experienced several side effects, including:
  • Herpes Zoster
  • Pain
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Fluorouracil side effects, such as Pain.
Pain, Insomnia, Burning Sensation

A patient from US was prescribed and started Fluorouracil 5% Cre Qty 40 1x Per Day Oceanside Pharmaceuticals on Oct 23, 2013. Patient felt the following Fluorouracil side effects: pain, insomnia, burning sensation Additional patient health information: male , 81 years of age, weighting 190.0 lb, The consumer reported the following symptoms: was diagnosed with and. Fluorouracil 5% Cre Qty 40 1x Per Day Oceanside Pharmaceuticals dosage: 5% 1 Application Per Day At Bedtime Rubbed On Face, Ears And Behind Ear.. Concurrently used drugs:
  • Allopurinol
  • Simvastatin
  • Montelukast
  • Lisinopril
  • Omeprazole
  • Alprazolam
  • Aspirin
Dyspnoea, Fatigue, Nausea, Vomiting, Stomatitis, Diarrhoea, Pain, Formication, Skin Lesion

This report suggests a potential Fluorouracile Teva Pain side effect(s) that can have serious consequences. A 74-year-old female patient from IT (weight:NA) was diagnosed with the following health condition(s): adenocarcinoma of colon and used Fluorouracile Teva (dosage: 519 Milligram Daily;) starting Dec 12, 2012. Soon after starting Fluorouracile Teva the patient began experiencing various side effects, including:
  • Dyspnoea
  • Fatigue
  • Nausea
  • Vomiting
  • Stomatitis
  • Diarrhoea
  • Pain
  • Formication
  • Skin Lesion
Drugs used concurrently:NA. Although Fluorouracile Teva demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pain, may still occur.
Hepatic Failure, Haemoglobin Decreased, Platelet Count Decreased, Pain, Fatigue, Hypersomnia, C-reactive Protein Increased, Lipase Decreased

An adverse event was reported by a consumer or non-health professional on Oct 28, 2013 by a Female taking Fluorouracil (dosage: 640 Mg, Every Cycle, Intravenous Bolus) was diagnosed with and. Location: DE , 62 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Fluorouracil side effects: hepatic failure, haemoglobin decreased, platelet count decreased, pain, fatigue, hypersomnia, c-reactive protein increased, lipase decreased. Additional medications/treatments:
Associated medications used:
  • Aflibercept
  • Irinotecan (iriotecan) (irinotecan) (290 Mg, Every Cycle, Intravenous (not Otherwise Specified))
  • Leucovorin (640 Mg, Every Cycle, Intravenous (not Otherwise Specified))
  • Analgesics (analgesics)
  • Granulocyte Colony-stimulating Factor Nos
  • Antihypertensives
The patient was hospitalized.
Pruritus, Swelling, Pain, Lip Swelling, Oedema Mouth, Lip Haemorrhage, Gingival Swelling, Temperature Intolerance, Insomnia

This Pain problem was reported by a consumer or non-health professional from US. A 79-year-old patient (weight: NA) was diagnosed with the following medical condition(s): skin cancer.On Mar 04, 2013 a consumer started treatment with Fluorouracil (dosage: Thin Layer To Face /+neck For 2 Wks Am + Pm Rub On). The following drugs/medications were being taken at the same time: NA. When commencing Fluorouracil, the patient experienced the following unwanted symptoms /side effects:
  • Pruritus
  • Swelling
  • Pain
  • Lip Swelling
  • Oedema Mouth
  • Lip Haemorrhage
  • Gingival Swelling
  • Temperature Intolerance
  • Insomnia
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Pain, may become evident only after a product is in use by the general population.
Pain, Heart Rate Increased, Headache, Anxiety, Blood Pressure Increased, Abdominal Pain, Feeling Abnormal, Diverticulum, Hepatic Steatosis

This is a Fluorouracil side effect report of a 72-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Fluorouracil (dosage: NA) starting Feb 01, 2013. Concurrently used drugs:
  • Pravastatin
  • Coumadin
Soon after that, the consumer experienced the following of symptoms:
  • Pain
  • Heart Rate Increased
  • Headache
  • Anxiety
  • Blood Pressure Increased
  • Abdominal Pain
  • Feeling Abnormal
  • Diverticulum
  • Hepatic Steatosis
This opens a possibility that Fluorouracil could cause Pain and that some female patients may be more susceptible.
Oral Pain, Fatigue, Stomatitis, Decreased Appetite, Dehydration, Hyponatraemia, Urine Osmolarity Increased, Weight Decreased

This Pain side effect was reported by a consumer or non-health professional from US on Feb 06, 2013. A patient from US , weighting 105.2 lb, was treated with Fluorouracil. Directly after treatment started, patient experienced the unwanted or unexpected Fluorouracil side effects: oral pain, fatigue, stomatitis, decreased appetite, dehydration, hyponatraemia, urine osmolarity increased, weight decreased. Fluorouracil dosage: NA.
Associated medications used:
  • Oxaliplatin
These side effects may potentially be related to Fluorouracil.
Diarrhoea, Hypotension, Syncope, Loss Of Consciousness, Pain, Lacrimation Increased, Oedema, Salivary Hypersecretion, Musculoskeletal Chest Pain

This Pain side effect was reported by a physician from IT. A 54-year-old patient (weight:NA) experienced the following symptoms/conditions: colon cancer. The patient was prescribed Fluorouracil (dosage: 704 Milligram Daily;), which was started on Dec 06, 2012. Concurrently used drugs: NA. When starting to take Fluorouracil the consumer reported the following symptoms:
  • Diarrhoea
  • Hypotension
  • Syncope
  • Loss Of Consciousness
  • Pain
  • Lacrimation Increased
  • Oedema
  • Salivary Hypersecretion
  • Musculoskeletal Chest Pain
These side effects may potentially be related to Fluorouracil.
Orchitis, Pyrexia, Hydrocele, Scrotal Swelling, Pain, Hyperaemia, Testicular Disorder

This Pain Fluorouracil side effect was reported by a health professional from GB on Jan 09, 2013. A male , 53 years of age, weighting 152.1 lb, was diagnosed with and was treated with Fluorouracil. The patient presented the following health conditions:
  • Orchitis
  • Pyrexia
  • Hydrocele
  • Scrotal Swelling
  • Pain
  • Hyperaemia
  • Testicular Disorder
. Fluorouracil dosage: NA. Additional drugs used at the same time:
  • Folinic Acid
  • Eloxatin
  • Irinotecan
The patient was hospitalized.
Clostridium Difficile Colitis, Vomiting, Pain, Nausea, Dehydration

This is a Fluorouracil side effect report of a 49-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: colorectal cancer,metastases to liver, who was treated with Fluorouracil (dosage:NA, start time: Oct 09, 2012), combined with: NA., and developed a serious reaction and a Pain side effect. The patient presented with:
  • Clostridium Difficile Colitis
  • Vomiting
  • Pain
  • Nausea
  • Dehydration
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Fluorouracil treatment in female patients suffering from colorectal cancer,metastases to liver, resulting in Pain.
Clostridium Difficile Colitis, Vomiting, Pain, Nausea, Dehydration

A 49-year-old female patient (weight: NA) from US with the following symptoms: colorectal cancer,metastases to liver started Fluorouracil treatment (dosage: NA) on Oct 09, 2012. Soon after starting Fluorouracil treatment, the consumer experienced several side effects, including:
  • Clostridium Difficile Colitis
  • Vomiting
  • Pain
  • Nausea
  • Dehydration
. Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Fluorouracil side effects, such as Pain.
Clostridium Difficile Colitis, Pain

A female patient from US was prescribed and started Fluorouracil on Mar 22, 2013. After Fluorouracil was administered, patient encountered several Fluorouracil side effects: clostridium difficile colitis, pain Additional patient health information: Female , 49 years of age, weighting 151.2 lb, The consumer reported the following symptoms: was diagnosed with and. Fluorouracil dosage: 736 Mg, Cyclic, Ivp. Concurrently used drugs: NA. The patient was hospitalized.
Pain, Musculoskeletal Stiffness, Swelling, Paraesthesia, Myalgia, Xerophthalmia, Dry Mouth

This report suggests a potential Fluorouracil (fluorouracil) Pain side effect(s) that can have serious consequences. A 71-year-old female patient from IT (weight:NA) was diagnosed with the following health condition(s): rectal cancer,metastases to lung and used Fluorouracil (fluorouracil) (dosage: (1 G/m2)) starting 200702. Soon after starting Fluorouracil (fluorouracil) the patient began experiencing various side effects, including:
  • Pain
  • Musculoskeletal Stiffness
  • Swelling
  • Paraesthesia
  • Myalgia
  • Xerophthalmia
  • Dry Mouth
Drugs used concurrently:NA. Although Fluorouracil (fluorouracil) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pain, may still occur.
Pyrexia, Mucosal Inflammation, Pancytopenia, Neutropenia, Thrombocytopenia, Pain

An adverse event was reported by a health professional on May 16, 2012 by a male taking Fluorouracil (dosage: 3000 Mg/m2, Cyclic) was diagnosed with and. Location: FRANCE , 70 years of age, weighting 143.3 lb, patient began experiencing various side effects, including: Patient felt the following Fluorouracil side effects: pyrexia, mucosal inflammation, pancytopenia, neutropenia, thrombocytopenia, pain. Additional medications/treatments:
Multiple prescriptions taken:
  • Methylprednisolone (60 Mg, Cyclic)
  • Leucovorin Calcium (400 Mg/m2, Cyclic)
  • Morphine (Unk)
  • Lovenox (0.4 Ml, Unk)
  • Leucovorin Calcium (400 Mg/m2, Cyclic)
  • Irbesartan (Unk)
The patient was hospitalized.
Pain, Skin Reaction, Pruritus

This Pain problem was reported by a health professional from FRANCE. A 73-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Jul 22, 2004 a consumer started treatment with Fluorouracil (dosage: 4800 Mg (2400 Mg/m2), Unk). The following drugs/medications were being taken at the same time:
  • Cetuximab (Every 15 Days)
When commencing Fluorouracil, the patient experienced the following unwanted symptoms /side effects:
  • Pain
  • Skin Reaction
  • Pruritus
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Pain, may become evident only after a product is in use by the general population.
Mouth Ulceration, Pain, Dysphagia, Stomatitis

This is a Fluorouracil side effect report of a 27-year-old patient (weight: NA) from JAPAN. The patient developed the following symptoms/conditions: NA and was treated with Fluorouracil (dosage: Dose Unit:600) starting NS. Concurrently used drugs:
  • Taxotere (Dose Unit:50)
  • Cisplatin (Dose Unit:60)
Soon after that, the consumer experienced the following of symptoms:
  • Mouth Ulceration
  • Pain
  • Dysphagia
  • Stomatitis
The patient was hospitalized. This opens a possibility that Fluorouracil could cause Pain and that some patients may be more susceptible.
Bone Marrow Failure, Pain

This Pain side effect was reported by a health professional from JAPAN on Dec 05, 2011. A female patient from JAPAN , 81 years of age, was treated with Fluorouracil. Patient felt the following Fluorouracil side effects: bone marrow failure, pain. Fluorouracil dosage: Unk Ukn, Unk.
Multiple prescriptions taken:
  • Cyclophosphamide (Unk Ukn, Unk)
  • Doxorubicin Hydrochloride (Unk Ukn, Unk)
  • Zometa
  • Femara
These side effects may potentially be related to Fluorouracil.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Fluorouracil Pain Causes and Reviews


Pain is a signal in your nervous system that something may be wrong. It is an unpleasant feeling, such as a prick, tingle, sting, burn, or ache. Pain may be sharp or dull. It may come and go, or it may be constant. You may feel Pain in one area of your body, such as your back, abdomen, chest, pelvis, or you may feel Pain all over

Pain can be helpful in diagnosing a problem. If you never felt Pain, you might seriously hurt yourself without knowing it, or you might not realize you have a medical problem that needs treatment.

There are two types of Pain: acute and chronic. Acute Pain usually comes on suddenly, because of a disease, injury, or inflammation. It can often be diagnosed and treated. It usually goes away, though sometimes it can turn into chronic Pain. Chronic Pain lasts for a long time, and can cause severe problems.

Pain is not always curable, but there are many ways to treat it. Treatment depends on the cause and type of Pain. Pain relievers and other medicines, acupuncture, physical therapy, and sometimes surgery may be helpful.

NIH: National Institute of Neurological Disorders and Stroke


Fluorouracil Pain Reviews

Fri, 20 May 2011

Why do doctors keep the availabilty of the test for DPD deficiency a secret??? My sister is a doctor, infectious disease, at St Francis in Charleston, SC. Our father was treated by an oncologist well known to my sister, a "colleague" you might say and he did not tell her about the test for DPD sensitivity or the possibility of a neurotoxic reaction due to the lack of or under production of this enzyme.
Up until last July, 2010, Our father was enjoying an active retirement which included fishing and riding his bike all over Charleston, after treatment with 5FU and mycomicin, for a NON METASTISIZED squamous cell anal tumor he is in a nursing home with Painfull neuropothy, and atrophy and damage to the myelin in his brain.
I found out that since 2009 there is even an antidote to 5FU overdose, which is what the DPD deficiency causes since the person cannot clear it from the system. The antidote is Uridine Triacetate or Vistonuridine made by Wellstat Therapeutics. It displaces the 5FU in the system preventing the neurological damage. If used within 96 hours after treatment all neurotoxic effects are elliminated.
I wanted to sue for this grotesque carelessness and lack of honesty by the physician who administered this evil drug but I cannot even do that. My sister says that it would ruin her career as other doctors would seek revenge against the "family that sued a doctor". She would be ostracized and never have any more patients referred to her. She says she would have to leave town and would probably end up loosing her house.
How can we trust physicians who would not only withhold important information from their patients; but, also use their lives in some sort of money making roulette game---And then also turn against one of their own just because her sister sued one of them due to the uneccessary chemical destruction of their father??? Doctors are starting to look like a pack of snakes to me.
I'm staying far far away from them all.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Fluorouracil Side Effects

Diarrhoea (463)
Nausea (335)
Dehydration (273)
Vomiting (266)
Neutropenia (243)
Febrile Neutropenia (207)
Pyrexia (187)
Mucosal Inflammation (179)
Asthenia (158)
Abdominal Pain (152)
Stomatitis (143)
Fatigue (134)
Dyspnoea (131)
Interstitial Lung Disease (117)
Decreased Appetite (116)
Pulmonary Embolism (111)
Chest Pain (110)
Anaemia (106)
Thrombocytopenia (106)
Hypotension (106)
Neutrophil Count Decreased (99)
Hypokalaemia (95)
Leukopenia (83)
Sepsis (78)
White Blood Cell Count Decreased (78)
Renal Failure Acute (75)
Pneumonia (75)
Malaise (74)
Haemoglobin Decreased (72)
Neuropathy Peripheral (69)
Pain (69)
Renal Failure (64)
Disease Progression (64)
Respiratory Failure (62)
Cardiotoxicity (62)
Dysphagia (61)
Confusional State (57)
Platelet Count Decreased (57)
Pancytopenia (55)
Fall (55)
Deep Vein Thrombosis (54)
Myocardial Infarction (53)
Arteriospasm Coronary (51)
Hyponatraemia (51)
Weight Decreased (51)
Tachycardia (48)
Chills (46)
Dizziness (46)
Septic Shock (46)
Hyperammonaemia (46)

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