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Fluorouracil Respiratory Failure Side Effects

Fluorouracil Respiratory Failure Side Effect Reports


The following Fluorouracil Respiratory Failure side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Respiratory Failure, can occur, and what you can do about them.

A side effect could appear soon after you start Fluorouracil or it might take time to develop.



Pneumocystis Jirovecii Pneumonia, Respiratory Failure, Febrile Neutropenia

This Respiratory Failure side effect was reported by a health professional from JP. A 72-year-old female patient (weight:NA) experienced the following symptoms/conditions: breast cancer. The patient was prescribed Fluorouracil (fluorouracil) (fluorouracil) (dosage: NA), which was started on NS. Concurrently used drugs:
  • Epirubicin (epirubicin) (epirubicin)
  • Cyclophosphamide (cyclophosphamide) (cyclophosphamide)
  • Dexamethasone (dexamethasone) (dexamethasone)
When starting to take Fluorouracil (fluorouracil) (fluorouracil) the consumer reported the following symptoms:
  • Pneumocystis Jirovecii Pneumonia
  • Respiratory Failure
  • Febrile Neutropenia
The patient was hospitalized. These side effects may potentially be related to Fluorouracil (fluorouracil) (fluorouracil).
Pneumocystis Jirovecii Pneumonia, Febrile Neutropenia, Pyrexia, Dyspnoea, Respiratory Failure, Fatigue

This Respiratory Failure Fluorouracil side effect was reported by a physician from JP on Dec 11, 2013. A Female , 72 years of age, was diagnosed with and was treated with Fluorouracil. The patient presented the following health conditions:
  • Pneumocystis Jirovecii Pneumonia
  • Febrile Neutropenia
  • Pyrexia
  • Dyspnoea
  • Respiratory Failure
  • Fatigue
. Fluorouracil dosage: 500 Mg/m2 On Day 1 Within A 3 Week Period. Additional drugs used at the same time:
  • Epirubicin (100 Mg/m2 On Day 1 Within A 3 Week Period)
  • Cyclophosphamide (500 Mg/m2 On Day 1 Within A 3 Week Period)
  • Dexamethasone (9.9 Mg, Single)
  • Dexamethasone
The patient was hospitalized.
Tumour Lysis Syndrome, Metabolic Acidosis, Hypotension, Respiratory Failure, Haematemesis, Melaena, Nausea, Decreased Appetite

This is a Fluorouracil side effect report of a 80-year-old patient (weight:NA) from TW, suffering from the following symptoms/conditions: colon cancer metastatic, who was treated with Fluorouracil (dosage:Unk, start time: Jun 05, 2012), combined with:
  • Irinotecan (144 Mg/m2, Qd)
  • Folinic Acid (Unk)
  • Bevacizumab (300 Mg, Qd)
, and developed a serious reaction and a Respiratory Failure side effect. The patient presented with:
  • Tumour Lysis Syndrome
  • Metabolic Acidosis
  • Hypotension
  • Respiratory Failure
  • Haematemesis
  • Melaena
  • Nausea
  • Decreased Appetite
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Fluorouracil treatment in patients suffering from colon cancer metastatic, resulting in Respiratory Failure.

Febrile Neutropenia, Dyspnoea, Sepsis, Respiratory Failure, Disseminated Intravascular Coagulation

A 27-year-old patient (weight: NA) from TH with the following symptoms: colorectal cancer metastatic started Fluorouracil treatment (dosage: NA) on Oct 28, 2013. Soon after starting Fluorouracil treatment, the consumer experienced several side effects, including:
  • Febrile Neutropenia
  • Dyspnoea
  • Sepsis
  • Respiratory Failure
  • Disseminated Intravascular Coagulation
. Concurrently used drugs:
  • Aflibercept (aflibercept) (solution For Infusion) (aflibercept)
  • Irinotecan (irinotecan) (solution For Infusion) (irinotecan)
  • Leucovorin (folinic Acid) (solution For Infusion) (folinic Acid)
  • Serontonin Antagonists (serotonin Antagonists)
  • Corticosteroids (corticosteroids)
  • Anticholinergics (anticholinergics)
  • Metoclopramide (metoclopramide) (metoclopramide)
  • Lorazepam (lorazepam) (lorazepam)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Fluorouracil side effects, such as Respiratory Failure.
White Blood Cell Count Decreased, Neutrophil Count Decreased, Interstitial Lung Disease, Disseminated Intravascular Coagulation, Respiratory Failure, Diffuse Alveolar Damage

A patient from JP was prescribed and started Fluorouracil on Nov 04, 2013. Patient felt the following Fluorouracil side effects: white blood cell count decreased, neutrophil count decreased, interstitial lung disease, disseminated intravascular coagulation, respiratory failure, diffuse alveolar damage Additional patient health information: male , 73 years of age, weighting 132.3 lb, The consumer reported the following symptoms: was diagnosed with and. Fluorouracil dosage: NA. Concurrently used drugs:
  • Elplat
  • Vectibix
  • Calcium Levofolinate(calcium Levofolinate)(calciui Levofolinate)
  • Ceftriaxone Sodium(ceftriaxone Sodium)(ceftriaxon) Sodium)
  • Aloxi(palonosetron Hydrochloride)(palonosetron Hydrochloride)
  • Chlorphenamine Maleate(chlorphenamine Maleate) (chlorphenamine Maleate)
  • Dexart(dexamethasone Sodium Phosphate)(dexamethasone Sodium Phosphate)
  • Pazufloxacin(pazufloxacin)(pazufloxacin)
Interstitial Lung Disease, C-reactive Protein Increased, Dyspnoea, Blood Lactate Dehydrogenase Increased, Cell Marker Increased, Respiratory Failure

This report suggests a potential Fluorouracil Respiratory Failure side effect(s) that can have serious consequences. A 69-year-old patient from JP (weight:NA) was diagnosed with the following health condition(s): rectal cancer,metastases to liver and used Fluorouracil (dosage: Bolus) starting 2010. Soon after starting Fluorouracil the patient began experiencing various side effects, including:
  • Interstitial Lung Disease
  • C-reactive Protein Increased
  • Dyspnoea
  • Blood Lactate Dehydrogenase Increased
  • Cell Marker Increased
  • Respiratory Failure
Drugs used concurrently:NA. The patient was hospitalized. Although Fluorouracil demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Respiratory Failure, may still occur.
Interstitial Lung Disease, Respiratory Distress, Condition Aggravated, Respiratory Failure

An adverse event was reported by a health professional on Jun 28, 2013 by a male taking Fluorouracil (dosage: NA) was diagnosed with and. Location: JP , 69 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Fluorouracil side effects: interstitial lung disease, respiratory distress, condition aggravated, respiratory failure. Additional medications/treatments: The patient was hospitalized.
Oesophageal Fistula, Pneumonia, Respiratory Failure

This Respiratory Failure problem was reported by a health professional from JP. A 75-year-old patient (weight: NA) was diagnosed with the following medical condition(s): oesophageal carcinoma.On NS a consumer started treatment with Fluorouracil (dosage: NA). The following drugs/medications were being taken at the same time:
  • Cisplatin
  • Therapeutic Radiopharmaceuticals (therapeutic Radiopharmaceuticals) (61.2 Gy)
When commencing Fluorouracil, the patient experienced the following unwanted symptoms /side effects:
  • Oesophageal Fistula
  • Pneumonia
  • Respiratory Failure
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Respiratory Failure, may become evident only after a product is in use by the general population.
Respiratory Failure, Pneumonia, Oesophageal Fistula

This is a Fluorouracil side effect report of a 70-year-old patient (weight: NA) from JP. The patient developed the following symptoms/conditions: oesophageal carcinoma and was treated with Fluorouracil (dosage: NA) starting NS. Concurrently used drugs:
  • Cisplatin
Soon after that, the consumer experienced the following of symptoms:
  • Respiratory Failure
  • Pneumonia
  • Oesophageal Fistula
This opens a possibility that Fluorouracil could cause Respiratory Failure and that some patients may be more susceptible.
Oesophageal Fistula, Pneumonia, Respiratory Failure

This Respiratory Failure side effect was reported by a health professional from JP on Mar 22, 2013. A patient from JP , 67 years of age, was diagnosed with and was treated with Fluorouracil. Directly after treatment started, patient experienced the unwanted or unexpected Fluorouracil side effects: oesophageal fistula, pneumonia, respiratory failure. Fluorouracil dosage: NA.
Associated medications used:
  • Cisplatin
  • Therapeutic Radiopharmaceuticals (therapeutic Pharm Aceuticals)
These side effects may potentially be related to Fluorouracil.
Respiratory Failure

This Respiratory Failure side effect was reported by a physician from US. A 73-year-old patient (weight:NA) experienced the following symptoms/conditions: colon cancer. The patient was prescribed Fluorouracil (dosage: Day 1 And Day 15), which was started on 201210. Concurrently used drugs: NA. When starting to take Fluorouracil the consumer reported the following symptoms:
  • Respiratory Failure
The patient was hospitalized. These side effects may potentially be related to Fluorouracil.
Interstitial Lung Disease, Respiratory Failure, Haemoptysis, Pulmonary Oedema, Pulmonary Alveolar Haemorrhage

This Respiratory Failure Fluorouracil side effect was reported by a health professional from AU on Mar 01, 2013. A male , 74 years of age, was diagnosed with and was treated with Fluorouracil. The patient presented the following health conditions:
  • Interstitial Lung Disease
  • Respiratory Failure
  • Haemoptysis
  • Pulmonary Oedema
  • Pulmonary Alveolar Haemorrhage
. Fluorouracil dosage: NA. Additional drugs used at the same time:
  • Oxaliplatin
  • Leucovorin
The patient was hospitalized.
Interstitial Lung Disease, C-reactive Protein Increased, Haemoptysis, Dyspnoea, Respiratory Failure

This is a Fluorouracil side effect report of a 74-year-old patient (weight:NA) from AU, suffering from the following symptoms/conditions: colon cancer metastatic, who was treated with Fluorouracil (dosage:6 Cycles, start time: 200810), combined with:
  • Oxaliplatin (6 Cycles)
  • Leucovorin (6 Cycles)
, and developed a serious reaction and a Respiratory Failure side effect. The patient presented with:
  • Interstitial Lung Disease
  • C-reactive Protein Increased
  • Haemoptysis
  • Dyspnoea
  • Respiratory Failure
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Fluorouracil treatment in patients suffering from colon cancer metastatic, resulting in Respiratory Failure.
Respiratory Failure, Tumour Necrosis, Oesophageal Rupture, Oesophagobronchial Fistula

A 68-year-old patient (weight: NA) from JP with the following symptoms: oesophageal carcinoma started Fluorouracil (fluorouracil) treatment (dosage: NA) on Feb 16, 2012. Soon after starting Fluorouracil (fluorouracil) treatment, the consumer experienced several side effects, including:
  • Respiratory Failure
  • Tumour Necrosis
  • Oesophageal Rupture
  • Oesophagobronchial Fistula
. Concurrently used drugs:
  • Cisplatin (cisplatin) ((df))
  • Docetaxel (docetaxel) ((df))
  • Ropion
  • Aloxi
  • Dexamethasone Sodium Phosphate
  • Mannigen
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Fluorouracil (fluorouracil) side effects, such as Respiratory Failure.
Malaise, Pleuritic Pain, Respiratory Failure, Sepsis

A patient from GB was prescribed and started Fluorouracil on Jan 22, 2013. After Fluorouracil was administered, patient encountered several Fluorouracil side effects: malaise, pleuritic pain, respiratory failure, sepsis Additional patient health information: male , 73 years of age, The consumer reported the following symptoms: was diagnosed with and. Fluorouracil dosage: NA. Concurrently used drugs:
  • Aflibercept
  • Irinotecan
  • Leucovorin
  • Lansoprazole
  • Co-codamol
  • Movicol
  • Loperamide
  • Rectogesic
The patient was hospitalized.
Tumour Necrosis, Oesophageal Perforation, Oesophagobronchial Fistula, Productive Cough, Insomnia, Respiratory Failure, Respiratory Depression, Altered State Of Consciousness, Dyspnoea

This report suggests a potential Fluorouracil Respiratory Failure side effect(s) that can have serious consequences. A 68-year-old patient from JP (weight:NA) was diagnosed with the following health condition(s): oesophageal carcinoma and used Fluorouracil (dosage: On Day 1-5, Every 4 Weeks) starting Feb 16, 2012. Soon after starting Fluorouracil the patient began experiencing various side effects, including:
  • Tumour Necrosis
  • Oesophageal Perforation
  • Oesophagobronchial Fistula
  • Productive Cough
  • Insomnia
  • Respiratory Failure
  • Respiratory Depression
  • Altered State Of Consciousness
  • Dyspnoea
Drugs used concurrently:
  • Cisplatin (On Day 1)
  • Docetaxel (On Day 1)
  • Ropion
  • Aloxi
  • Dexamethasone Sodium Phosphate
  • Mannigen (20 Percent)
The patient was hospitalized. Although Fluorouracil demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Respiratory Failure, may still occur.
Multi-organ Failure, Cardiac Failure Congestive, Renal Failure Acute, Renal Failure Chronic, Respiratory Failure, Leukoencephalopathy, Pancytopenia, Hypotension, Nausea

An adverse event was reported by a physician on Nov 15, 2012 by a Female taking Fluorouracil (dosage: Unk) was diagnosed with and. Location: US , 51 years of age, patient began experiencing various side effects, including: Patient felt the following Fluorouracil side effects: multi-organ failure, cardiac failure congestive, renal failure acute, renal failure chronic, respiratory failure, leukoencephalopathy, pancytopenia, hypotension, nausea. Additional medications/treatments:
Multiple prescriptions taken:
  • Leucovorin (Unk)
  • Oxaliplatin (Unk)
  • Irinotecan (Unk)
Respiratory Failure

This Respiratory Failure problem was reported by a physician from GERMANY. A 75-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): colon cancer.On Dec 01, 2011 a consumer started treatment with Fluorouracil (dosage: NA). The following drugs/medications were being taken at the same time:
  • Leucovorin Calcium
  • Oxaliplatin
  • Avastin
When commencing Fluorouracil, the patient experienced the following unwanted symptoms /side effects:
  • Respiratory Failure
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Respiratory Failure, may become evident only after a product is in use by the general population.
Candida Test Positive, Abdominal Compartment Syndrome, Epistaxis, Urticaria, Pleural Effusion, Haemorrhage, Blood Culture Positive, Respiratory Failure, Caecitis

This is a Fluorouracil side effect report of a female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Fluorouracil (dosage: 330 Mg) starting NS. Concurrently used drugs:
  • Cisplatin (55 Mg)
  • Doxorubicin Hcl (34 Mg)
  • Vincristine Sulfate (.8 Mg)
Soon after that, the consumer experienced the following of symptoms:
  • Candida Test Positive
  • Abdominal Compartment Syndrome
  • Epistaxis
  • Urticaria
  • Pleural Effusion
  • Haemorrhage
  • Blood Culture Positive
  • Respiratory Failure
  • Caecitis
The patient was hospitalized. This opens a possibility that Fluorouracil could cause Respiratory Failure and that some female patients may be more susceptible.
Interstitial Lung Disease, Respiratory Failure

This Respiratory Failure side effect was reported by a physician from JAPAN on Feb 28, 2012. A patient from JAPAN , 49 years of age, weighting 147.7 lb, was diagnosed with and was treated with Fluorouracil. Patient felt the following Fluorouracil side effects: interstitial lung disease, respiratory failure. Fluorouracil dosage: 750 Mg, Unk.
Multiple prescriptions taken:
  • Isovorin (200 Mg, Unk)
  • Kytril (Unk)
  • Decadron (Unk)
  • Irinotecan Hcl (280 Mg, Q2wk)
  • Solu-medrol (Unk)
  • Panitumumab (430 Mg, Q2wk)
These side effects may potentially be related to Fluorouracil.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Fluorouracil Respiratory Failure Causes and Reviews


What is respiratory failure?

Respiratory failure is a condition in which your blood doesn't have enough oxygen or has too much carbon dioxide. Sometimes you can have both problems.

When you breathe, your lungs take in oxygen. The oxygen passes into your blood, which carries it to your organs. Your organs, such as your heart and brain, need this oxygen-rich blood to work well.

Another part of breathing is removing the carbon dioxide from the blood and breathing it out. Having too much carbon dioxide in your blood can harm your organs.

What causes respiratory failure?

Conditions that affect your breathing can cause respiratory failure. These conditions may affect the muscles, nerves, bones, or tissues that support breathing. Or they may affect the lungs directly. These conditions include

  • Lung diseases such as COPD (chronic obstructive pulmonary disease), cystic fibrosis, pneumonia, and pulmonary embolism
  • Conditions that affect the nerves and muscles that control breathing, such as amyotrophic lateral sclerosis (ALS), muscular dystrophy, spinal cord injuries, and stroke
  • Problems with the spine, such as scoliosis (a curve in the spine). They can affect the bones and muscles used for breathing.
  • Damage to the tissues and ribs around the lungs. An injury to the chest can cause this damage.
  • Drug or alcohol overdose
  • Inhalation injuries, such as from inhaling smoke (from fires) or harmful fumes
What are the symptoms of respiratory failure?

The symptoms of respiratory failure depend on the cause and the levels of oxygen and carbon dioxide in your blood.

A low oxygen level in the blood can cause shortness of breath and air hunger (the feeling that you can't breathe in enough air). Your skin, lips, and fingernails may also have a bluish color. A high carbon dioxide level can cause rapid breathing and confusion.

Some people who have respiratory failure may become very sleepy or lose consciousness. They also may have arrhythmia (irregular heartbeat). You may have these symptoms if your brain and heart are not getting enough oxygen.

How is respiratory failure diagnosed?

Your health care provider will diagnose respiratory failure based on

  • Your medical history
  • A physical exam, which often includes
    • Listening to your lungs to check for abnormal sounds
    • Listening to your heart to check for arrhythmia
    • Looking for a bluish color on your skin, lips, and fingernails
  • Diagnostic tests, such as
    • Pulse oximetry, a small sensor that uses a light to measure how much oxygen is in your blood. The sensor goes on the end of your finger or on your ear.
    • Arterial blood gas test, a test that measures the oxygen and carbon dioxide levels in your blood. The blood sample is taken from an artery, usually in your wrist.

Once you are diagnosed with respiratory failure, your provider will look for what is causing it. Tests for this often include a chest x-ray. If your provider thinks you may have arrhythmia because of the respiratory failure, you may have an EKG (electrocardiogram). This is simple, painless test that detects and records your heart's electrical activity.

What are the treatments for respiratory failure?

Treatment for respiratory failure depends on

  • Whether it is acute (short-term) or chronic (ongoing)
  • How severe it is
  • What is causing it

Acute respiratory failure can be a medical emergency. You may need treatment in intensive care unit at a hospital. Chronic respiratory failure can often be treated at home. But if your chronic respiratory failure is severe, you might need treatment in a long-term care center.

One of the main goals of treatment is to get oxygen to your lungs and other organs and remove carbon dioxide from your body. Another goal is to treat the cause of the condition. Treatments may include

  • Oxygen therapy, through a nasal cannula (two small plastic tubes that go in your nostrils) or through a mask that fits over your nose and mouth
  • Tracheostomy, a surgically-made hole that goes through the front of your neck and into your windpipe. A breathing tube, also called a tracheostomy, or trach tube, is placed in the hole to help you breathe.
  • Ventilator, a breathing machine that blows air into your lungs. It also carries carbon dioxide out of your lungs.
  • Other breathing treatments, such as noninvasive positive pressure ventilation (NPPV), which uses mild air pressure to keep your airways open while you sleep. Another treatment is a special bed that rocks back and forth, to help you breathe in and out.
  • Fluids, often through an intravenous (IV), to improve blood flow throughout your body. They also provide nutrition.
  • Medicines for discomfort
  • Treatments for the cause of the respiratory failure. These treatments may include medicines and procedures.

If you have respiratory failure, see your health care provider for ongoing medical care. Your provider may suggest pulmonary rehabilitation.

If your respiratory failure is chronic, make sure that you know when and where to get help for your symptoms. You need emergency care if you have severe symptoms, such as trouble catching your breath or talking. You should call your provider if you notice that your symptoms are worsening or if you have new signs and symptoms.

Living with respiratory failure may cause fear, anxiety, depression, and stress. Talk therapy, medicines, and support groups can help you feel better.

NIH: National Heart, Lung, and Blood Institute


Fluorouracil Respiratory Failure Reviews

Wed, 28 May 2014

The side effects of Fluorouracil are most likely to be minor and temporary.InternationalDrugMart

Fri, 20 May 2011

its not 1%---more like 14% and that may even be a conservative estimate--Your doctor is lieing to you--surprised???

Sun, 13 Mar 2011

My fiancee passed away on 3/7/2011 after her second round of 5FU. The oncologist had used the words "surprised" and "out of the ordinary" on her reaction to the first round because of the amount and severity of her side effects. He still gave her the same dosage for the second round. Ten days later, she was in ICU. Seven days after going to the hospital, she was dead. She was 47 and in incredible shape except for the colon cancer. The doctor told us that she was part of the 1% of the population that didn't have the enzyme to metabolize the 5FU but she wasn't given the test because of the low percentage. With that decision, the woman I loved is no longer here.Her name was Birgit.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Fluorouracil Side Effects

Diarrhoea (462)
Nausea (335)
Dehydration (273)
Vomiting (266)
Neutropenia (243)
Febrile Neutropenia (207)
Pyrexia (187)
Mucosal Inflammation (179)
Asthenia (158)
Abdominal Pain (151)
Stomatitis (143)
Fatigue (134)
Dyspnoea (131)
Interstitial Lung Disease (117)
Decreased Appetite (116)
Pulmonary Embolism (111)
Chest Pain (109)
Anaemia (106)
Hypotension (106)
Thrombocytopenia (106)
Neutrophil Count Decreased (99)
Hypokalaemia (95)
Leukopenia (83)
Sepsis (78)
White Blood Cell Count Decreased (78)
Renal Failure Acute (75)
Pneumonia (75)
Malaise (74)
Haemoglobin Decreased (72)
Neuropathy Peripheral (69)
Pain (69)
Renal Failure (64)
Disease Progression (64)
Cardiotoxicity (62)
Respiratory Failure (62)
Dysphagia (61)
Confusional State (57)
Platelet Count Decreased (57)
Pancytopenia (55)
Fall (55)
Deep Vein Thrombosis (54)
Myocardial Infarction (53)
Arteriospasm Coronary (51)
Hyponatraemia (51)
Weight Decreased (51)
Tachycardia (48)
Chills (46)
Dizziness (46)
Hyperammonaemia (46)
Septic Shock (46)

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Fluorouracil Common Side Effects

If you experienced any harmful or unwanted effects of Mucinex, please share your experience. This could help to raise awareness about Mucinex side effects, identify uknown risks and inform health professionals and patients taking Mucinex.

Examples: headache, dizziness

The most commonly reported Fluorouracil side effects (click to view or check a box to report):

Diarrhoea (462)
Nausea (335)
Dehydration (273)
Vomiting (266)
Neutropenia (243)
Febrile Neutropenia (207)
Pyrexia (187)
Mucosal Inflammation (179)
Asthenia (158)
Abdominal Pain (151)
Stomatitis (143)
Fatigue (134)
Dyspnoea (131)
Interstitial Lung Disease (117)
Decreased Appetite (116)
Pulmonary Embolism (111)
Chest Pain (109)
Anaemia (106)
Hypotension (106)
Thrombocytopenia (106)

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Discuss Fluorouracil Side Effects

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