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Fluorouracil Thrombocytopenia Side Effects

Fluorouracil Thrombocytopenia Side Effect Reports


The following Fluorouracil Thrombocytopenia side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Thrombocytopenia, can occur, and what you can do about them.

A side effect could appear soon after you start Fluorouracil or it might take time to develop.



Agitation, Confusional State, Disorientation, Thrombocytopenia

This Thrombocytopenia side effect was reported by a consumer or non-health professional from US. A 68-year-old patient (weight:NA) experienced the following symptoms/conditions: squamous cell carcinoma of the oral cavity. The patient was prescribed Fluorouracil (dosage: NA), which was started on Jan 21, 2014. Concurrently used drugs:
  • Carboplatin
  • Erbitux
  • Lovenox
  • Lovenox
  • Valproate Sodium
  • Esomeprazole Magnesium
  • Kardegic
  • Durogesic
When starting to take Fluorouracil the consumer reported the following symptoms:
  • Agitation
  • Confusional State
  • Disorientation
  • Thrombocytopenia
The patient was hospitalized. These side effects may potentially be related to Fluorouracil.
Neutropenia, Off Label Use, Thrombocytopenia

This Thrombocytopenia Fluorouracil (fluorouracil) side effect was reported by a consumer or non-health professional from CH on Mar 04, 2014. A male , 15 years of age, was diagnosed with and was treated with Fluorouracil (fluorouracil). The patient presented the following health conditions:
  • Neutropenia
  • Off Label Use
  • Thrombocytopenia
. Fluorouracil (fluorouracil) dosage: NA. Additional drugs used at the same time: NA.
Thrombocytopenia, Dehydration, Fall

This is a Fluorouracil side effect report of a 63-year-old patient (weight:NA) from US, suffering from the following symptoms/conditions: oesophageal carcinoma, who was treated with Fluorouracil (dosage:NA, start time: Jun 13, 2013), combined with:
  • Cisplatin
, and developed a serious reaction and a Thrombocytopenia side effect. The patient presented with:
  • Thrombocytopenia
  • Dehydration
  • Fall
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Fluorouracil treatment in patients suffering from oesophageal carcinoma, resulting in Thrombocytopenia.

Thrombocytopenia, Off Label Use, Neutropenia

A 46-year-old patient (weight: NA) from IT with the following symptoms: pancreatic carcinoma started Fluorouracil treatment (dosage: NA) on Dec 09, 2013. Soon after starting Fluorouracil treatment, the consumer experienced several side effects, including:
  • Thrombocytopenia
  • Off Label Use
  • Neutropenia
. Concurrently used drugs:
  • Lederfolin (175 Mg Powder For Solution For Infusion)
  • Oxaliplatin
  • Irinotecan (Irinotecan Hydrochloridetrihydrate)
This finding indicates that some patients can be more vulnerable to developing Fluorouracil side effects, such as Thrombocytopenia.
Leukopenia, Thrombocytopenia

A patient from JP was prescribed and started Fluorouracil on Jan 29, 2014. Patient felt the following Fluorouracil side effects: leukopenia, thrombocytopenia Additional patient health information: male , 43 years of age, The consumer reported the following symptoms: was diagnosed with and. Fluorouracil dosage: NA. Concurrently used drugs: NA.
Thrombocytopenia

This report suggests a potential Fluorouracil Thrombocytopenia side effect(s) that can have serious consequences. A 54-year-old patient from US (weight:NA) was diagnosed with the following health condition(s): NA and used Fluorouracil (dosage: NA) starting NS. Soon after starting Fluorouracil the patient began experiencing various side effects, including:
  • Thrombocytopenia
Drugs used concurrently:NA. Although Fluorouracil demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Thrombocytopenia, may still occur.
Portal Hypertension, Liver Disorder, Intrahepatic Portal Hepatic Venous Fistula, Thrombocytopenia

An adverse event was reported by a health professional on Dec 17, 2013 by a male taking Fluorouracil (dosage: NA) was diagnosed with and. Location: US , 57 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Fluorouracil side effects: portal hypertension, liver disorder, intrahepatic portal hepatic venous fistula, thrombocytopenia. Additional medications/treatments:
Associated medications used:
  • Oxaliplatin
  • Leucovorin Calcium
The patient was hospitalized.
Anaemia, Ecchymosis, Hypotension, Melaena, Rectal Haemorrhage, Thrombocytopenia

This Thrombocytopenia problem was reported by a pharmacist from IT. A 82-year-old patient (weight: NA) was diagnosed with the following medical condition(s): gastric cancer.On Nov 16, 2013 a consumer started treatment with Fluorouracile Teva (dosage: 500 Milligram Daily;). The following drugs/medications were being taken at the same time: NA. When commencing Fluorouracile Teva, the patient experienced the following unwanted symptoms /side effects:
  • Anaemia
  • Ecchymosis
  • Hypotension
  • Melaena
  • Rectal Haemorrhage
  • Thrombocytopenia
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Thrombocytopenia, may become evident only after a product is in use by the general population.
Arteriovenous Fistula, Portal Hypertension, Thrombocytopenia

This is a Fluorouracil side effect report of a 57-year-old patient (weight: NA) from US. The patient developed the following symptoms/conditions: intestinal adenocarcinoma and was treated with Fluorouracil (dosage: NA) starting 201204. Concurrently used drugs:
  • Folinic Acid
  • Oxaliplatin Injection 50mg/10 Ml+100mg/20ml
Soon after that, the consumer experienced the following of symptoms:
  • Arteriovenous Fistula
  • Portal Hypertension
  • Thrombocytopenia
This opens a possibility that Fluorouracil could cause Thrombocytopenia and that some patients may be more susceptible.
Arteriovenous Fistula, Portal Hypertension, Thrombocytopenia

This Thrombocytopenia side effect was reported by a physician from US on Dec 05, 2013. A patient from US , 57 years of age, was diagnosed with and was treated with Fluorouracil. Directly after treatment started, patient experienced the unwanted or unexpected Fluorouracil side effects: arteriovenous fistula, portal hypertension, thrombocytopenia. Fluorouracil dosage: NA.
Associated medications used:
  • Folinic Acid
  • Oxaliplatin
These side effects may potentially be related to Fluorouracil.
Portal Hypertension, Intrahepatic Portal Hepatic Venous Fistula, Abdominal Pain, Thrombocytopenia, Hepatic Steatosis, Hepatic Atrophy, Varices Oesophageal

This Thrombocytopenia side effect was reported by a health professional from US. A 57-year-old patient (weight:NA) experienced the following symptoms/conditions: colon cancer. The patient was prescribed Fluorouracil (dosage: NA), which was started on 201204. Concurrently used drugs:
  • Oxaliplatin
  • Leucovorin
When starting to take Fluorouracil the consumer reported the following symptoms:
  • Portal Hypertension
  • Intrahepatic Portal Hepatic Venous Fistula
  • Abdominal Pain
  • Thrombocytopenia
  • Hepatic Steatosis
  • Hepatic Atrophy
  • Varices Oesophageal
These side effects may potentially be related to Fluorouracil.
Febrile Neutropenia, Agranulocytosis, Thrombocytopenia

This Thrombocytopenia Fluorouracile Pfizer side effect was reported by a health professional from FR on Dec 02, 2013. A Female , 67 years of age, was diagnosed with and was treated with Fluorouracile Pfizer. The patient presented the following health conditions:
  • Febrile Neutropenia
  • Agranulocytosis
  • Thrombocytopenia
. Fluorouracile Pfizer dosage: 500 Mg/m2, Daily. Additional drugs used at the same time:
  • Epirubicin (100 Mg/m2, Daily)
  • Endoxan (500 Mg/m2, Daily)
  • Crestor
  • Lexomil
The patient was hospitalized.
Hepatic Fibrosis, Portal Hypertension, Splenomegaly, Hepatic Necrosis, Thrombocytopenia, Metastases To Liver

This is a Fluorouracil side effect report of a 45-year-old patient (weight:NA) from KR, suffering from the following symptoms/conditions: colon cancer, who was treated with Fluorouracil (dosage:NA, start time: NS), combined with:
  • Oxaliplatin
  • Folinic Acid
, and developed a serious reaction and a Thrombocytopenia side effect. The patient presented with:
  • Hepatic Fibrosis
  • Portal Hypertension
  • Splenomegaly
  • Hepatic Necrosis
  • Thrombocytopenia
  • Metastases To Liver
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Fluorouracil treatment in patients suffering from colon cancer, resulting in Thrombocytopenia.
Intrahepatic Portal Hepatic Venous Fistula, Abdominal Pain, Liver Function Test Abnormal, Thrombocytopenia, Portal Hypertension, Splenomegaly

A 57-year-old patient (weight: NA) from US with the following symptoms: colon cancer started Fluorouracil treatment (dosage: NA) on 201204. Soon after starting Fluorouracil treatment, the consumer experienced several side effects, including:
  • Intrahepatic Portal Hepatic Venous Fistula
  • Abdominal Pain
  • Liver Function Test Abnormal
  • Thrombocytopenia
  • Portal Hypertension
  • Splenomegaly
. Concurrently used drugs:
  • Oxaliplatin
  • Leucovorin
This finding indicates that some patients can be more vulnerable to developing Fluorouracil side effects, such as Thrombocytopenia.
Thrombocytopenia, Neutropenia, Hyponatraemia, Dysphagia, Diarrhoea, Nausea

A patient from IT was prescribed and started Fluorouracile Teva on Oct 29, 2013. After Fluorouracil was administered, patient encountered several Fluorouracil side effects: thrombocytopenia, neutropenia, hyponatraemia, dysphagia, diarrhoea, nausea Additional patient health information: male , 68 years of age, The consumer reported the following symptoms: was diagnosed with and. Fluorouracile Teva dosage: 4280 Mg Cyclical. Concurrently used drugs:
  • Irinotecan Kabi (275mg Cyclical)
  • Oxaliplatino Sun (130mg Cyclical)
  • Neulasta 6mg (1 Dosage Forms Daily;)
The patient was hospitalized.
Gouty Arthritis, Neutropenia, Thrombocytopenia

This report suggests a potential Fluorouracil Thrombocytopenia side effect(s) that can have serious consequences. A 66-year-old patient from US (weight:NA) was diagnosed with the following health condition(s): adenocarcinoma pancreas and used Fluorouracil (dosage: Infusion 225mg/m2 Daily Mon-fri; 3 Cycles With Concurrent Radiation) starting NS. Soon after starting Fluorouracil the patient began experiencing various side effects, including:
  • Gouty Arthritis
  • Neutropenia
  • Thrombocytopenia
Drugs used concurrently:
  • Gemcitabine (1000mg/m2 Weekly For 3 Doses; Then 3w On, 1w Off, Starting 4w After Chemoradiation)
  • Filgrastim
  • Colchicine
  • Allopurinol (100mg Daily)
Although Fluorouracil demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Thrombocytopenia, may still occur.
Hypotension, Tachycardia, Hypoxia, Arrhythmia, Cardiac Arrest, Leukopenia, Thrombocytopenia, Gastrointestinal Inflammation, Mucosal Inflammation

An adverse event was reported by a health professional on Sep 04, 2013 by a male taking Fluorouracil (dosage: NA) was diagnosed with and. Location: HR , 35 years of age, patient began experiencing various side effects, including: Patient felt the following Fluorouracil side effects: hypotension, tachycardia, hypoxia, arrhythmia, cardiac arrest, leukopenia, thrombocytopenia, gastrointestinal inflammation, mucosal inflammation. Additional medications/treatments:
Multiple prescriptions taken:
  • Irinotecan (irinotecan)
  • Leucovorin (calcium Folinate)
Aspartate Aminotransferase Abnormal, Alanine Aminotransferase Abnormal, Blood Alkaline Phosphatase Abnormal, Leukopenia, Thrombocytopenia, Haematotoxicity, Haemoglobin Abnormal, Granulocytopenia, Hepatotoxicity

This Thrombocytopenia problem was reported by a consumer or non-health professional from DE. A 64-year-old patient (weight: NA) was diagnosed with the following medical condition(s): colorectal cancer,metastases to liver.On NS a consumer started treatment with Fluorouracil (dosage: NA). The following drugs/medications were being taken at the same time: NA. When commencing Fluorouracil, the patient experienced the following unwanted symptoms /side effects:
  • Aspartate Aminotransferase Abnormal
  • Alanine Aminotransferase Abnormal
  • Blood Alkaline Phosphatase Abnormal
  • Leukopenia
  • Thrombocytopenia
  • Haematotoxicity
  • Haemoglobin Abnormal
  • Granulocytopenia
  • Hepatotoxicity
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Thrombocytopenia, may become evident only after a product is in use by the general population.
Mucosal Inflammation, Gastrointestinal Inflammation, Leukopenia, Thrombocytopenia, Arrhythmia, Toxicity To Various Agents, Cardiac Arrest, Hypoxia

This is a Fluorouracil (fluorouracil) (fluorouracil) side effect report of a 35-year-old patient (weight: NA) from HR. The patient developed the following symptoms/conditions: NA and was treated with Fluorouracil (fluorouracil) (fluorouracil) (dosage: NA) starting NS. Concurrently used drugs:
  • Irinotecan (irinotecan) (irinotecan)
  • Folinic Acid (folinic Acid) (folinic Acid)
Soon after that, the consumer experienced the following of symptoms:
  • Mucosal Inflammation
  • Gastrointestinal Inflammation
  • Leukopenia
  • Thrombocytopenia
  • Arrhythmia
  • Toxicity To Various Agents
  • Cardiac Arrest
  • Hypoxia
This opens a possibility that Fluorouracil (fluorouracil) (fluorouracil) could cause Thrombocytopenia and that some patients may be more susceptible.
Aspartate Aminotransferase Abnormal, Alanine Aminotransferase Abnormal, Blood Alkaline Phosphatase Abnormal, Leukopenia, Thrombocytopenia, Haemoglobin Abnormal, Granulocytopenia, Alopecia

This Thrombocytopenia side effect was reported by a physician from DE on Aug 28, 2013. A female patient from DE , 75 years of age, was diagnosed with and was treated with Fluorouracil. Patient felt the following Fluorouracil side effects: aspartate aminotransferase abnormal, alanine aminotransferase abnormal, blood alkaline phosphatase abnormal, leukopenia, thrombocytopenia, haemoglobin abnormal, granulocytopenia, alopecia. Fluorouracil dosage: 2600 Mg/m2 On D1, 8, 15, 22, 29, 36; Next Cycle Starts On D57.
Multiple prescriptions taken:
  • Oncofolic (500 Mg/m2 Continuous 24-h Infusion On D1, 8, 15, 22, 29, 36; Next Cycle Starts On D57)
  • Mitomycin (10 Mg/m2 Boluses On D1, 22; Next Cycle Starts On D57)
These side effects may potentially be related to Fluorouracil.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Fluorouracil Thrombocytopenia Causes and Reviews


Platelets are little pieces of blood cells. Platelets help wounds heal and prevent bleeding by forming blood clots. Your bone marrow makes platelets. Problems can result from having too few or too many platelets, or from platelets that do not work properly.

If your blood has a low number of platelets, it is called Thrombocytopenia. This can put you at risk for mild to serious bleeding. If your blood has too many platelets, you may have a higher risk of blood clots. With other platelet disorders, the platelets do not work as they should. For example, in von Willebrand Disease, the platelets cannot stick together or cannot attach to blood vessel walls. This can cause excessive bleeding.

Treatment of platelet disorders depends on the cause.

NIH: National Heart, Lung, and Blood Institute


Fluorouracil Thrombocytopenia Reviews

Wed, 28 May 2014

The side effects of Fluorouracil are most likely to be minor and temporary.InternationalDrugMart

Fri, 20 May 2011

its not 1%---more like 14% and that may even be a conservative estimate--Your doctor is lieing to you--surprised???

Sun, 13 Mar 2011

My fiancee passed away on 3/7/2011 after her second round of 5FU. The oncologist had used the words "surprised" and "out of the ordinary" on her reaction to the first round because of the amount and severity of her side effects. He still gave her the same dosage for the second round. Ten days later, she was in ICU. Seven days after going to the hospital, she was dead. She was 47 and in incredible shape except for the colon cancer. The doctor told us that she was part of the 1% of the population that didn't have the enzyme to metabolize the 5FU but she wasn't given the test because of the low percentage. With that decision, the woman I loved is no longer here.Her name was Birgit.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Fluorouracil Side Effects

Diarrhoea (463)
Nausea (335)
Dehydration (273)
Vomiting (266)
Neutropenia (243)
Febrile Neutropenia (207)
Pyrexia (187)
Mucosal Inflammation (179)
Asthenia (158)
Abdominal Pain (152)
Stomatitis (143)
Fatigue (134)
Dyspnoea (131)
Interstitial Lung Disease (117)
Decreased Appetite (116)
Pulmonary Embolism (111)
Chest Pain (110)
Anaemia (106)
Thrombocytopenia (106)
Hypotension (106)
Neutrophil Count Decreased (99)
Hypokalaemia (95)
Leukopenia (83)
Sepsis (78)
White Blood Cell Count Decreased (78)
Renal Failure Acute (75)
Pneumonia (75)
Malaise (74)
Haemoglobin Decreased (72)
Neuropathy Peripheral (69)
Pain (69)
Renal Failure (64)
Disease Progression (64)
Respiratory Failure (62)
Cardiotoxicity (62)
Dysphagia (61)
Confusional State (57)
Platelet Count Decreased (57)
Pancytopenia (55)
Fall (55)
Deep Vein Thrombosis (54)
Myocardial Infarction (53)
Arteriospasm Coronary (51)
Hyponatraemia (51)
Weight Decreased (51)
Tachycardia (48)
Chills (46)
Dizziness (46)
Septic Shock (46)
Hyperammonaemia (46)

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