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ABNORMAL BEHAVIOUR and Effexor

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ABNORMAL BEHAVIOUR Symptoms and Causes

Alcohol can harm your baby at any stage during a pregnancy. That includes the earliest stages, before you even know you are pregnant. Drinking during pregnancy can cause a group of conditions called fetal alcohol spectrum disorders (FASDs). Children who are born with FASD can have a mix of problems, such as medical, behavioral, educational, and social problems. The kinds of problems they have depend on which type of FASD they have. The problems could include

  • Abnormal facial features, such as a smooth ridge between the nose and upper lip
  • Small head size
  • Shorter-than-average height
  • Low body weight
  • Poor coordination
  • Hyperactive behavior
  • Difficulty with attention and memory
  • Learning disabilities and difficulty in school
  • Speech and language delays
  • Intellectual disability or low IQ
  • Poor reasoning and judgment skills
  • Sleep and sucking problems as a baby
  • Vision or hearing problems
  • Problems with the heart, kidneys, or bones

Fetal alcohol syndrome (FAS) is the most serious type of FASD. People with fetal alcohol syndrome have facial abnormalities, including wide-set and narrow eyes, growth problems and nervous system abnormalities.

Diagnosing FASD can be hard because there is no medical test for it. The health care provider will make a diagnosis by looking at the child's signs and symptoms, and will ask whether the mother drank alcohol during pregnancy.

FASDs last a lifetime. There is no cure for FASDs, but treatments can help. These include medicines to help with some symptoms, medical care for health problems, behavior and education therapy, and parent training. A good treatment plan is specific to the child's problems. It should include close monitoring, follow-ups, and changes when needed.

Certain "protective factors" can help reduce the effects of FASDs and help people who have them reach their full potential. They include

  • Diagnosis before 6 years of age
  • Loving, nurturing, and stable home environment during the school years
  • Absence of violence around them
  • Involvement in special education and social services

There is no known safe amount of alcohol during pregnancy. To prevent FASDs, you should not drink alcohol while you are pregnant, or when you might get pregnant.

Centers for Disease Control and Prevention

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Effexor Side Effects

Dizziness (758)
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Headache (543)
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Paraesthesia (420)
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Aggression (201)
Blood Pressure Increased (194)
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Weight Increased (163)
Abnormal Behaviour (151)
Dyspnoea (150)
Amnesia (150)
Intentional Overdose (136)
Irritability (135)
Abnormal Dreams (123)
Tinnitus (118)
Activities Of Daily Living Impaired (117)
Serotonin Syndrome (115)
Loss Of Consciousness (111)
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Arthralgia (110)
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Disorientation (108)
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Emotional Disorder (105)

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Recent Reviews

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Effexor raised my blood presure alot ,I had extreme painful headaches,rash that started on my face which was horrible,then spread to my chest,my neck was beat red I itched so badly.I think docotrs need to be more educated on this med before giveing i

Effexor was horrible for me...as soon as I started it I started having panic attacks worse than ever (supposed to help them) scary bad dreams, waking up in a sweat and not knowing who I was, then depression. The first day I expeirenced the panic atta

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Had effexor yesterday 75 mg not again nusea,blurred vision and today the worst longest headache I have ever had,GP didn't even check my BP before prescription.I am recovering from a fractured skull think I will deal with my depression without drugs

Headaches BAD and very sleepy and increased anxiety

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I agree, this has been a horrile drug experience for me as well .. Effexor should be OFF the market !!!! 46 yr old female, Baltimore MD USA

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ABNORMAL BEHAVIOUR Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Repetitive Transcranial Magnetic Stimulation Compared or Associated With Venlafaxine for Depressive Disorder
Condition: Depression
Interventions: Other: active rTMS and active Venlafaxine;   Other: active rTMS and sham Venlafaxine;   Other: sham rTMS and active Venlafaxine
Outcome Measures: The primary outcome measure is remission;   fMRI;   CGI;   QIDS-C30;   UKU Scale
2 Recruiting Venlafaxine PK Following Bariatric Surgery
Conditions: Roux en Y Gastric Bypass;   Sleeve Gastrectomy
Intervention: Drug: Venlafaxine IR and Venlafaxine XR
Outcome Measures: Venlafaxine Plasma Concentrations/Area-Under-the-Curve (AUC);   Secondary PK Characteristics (Composite)
3 Recruiting Study to Examine the Effect of Gastric Bypass Surgery on Venlafaxine ER Blood Levels
Conditions: Bariatric Surgery;   Gastric Bypass;   Roux-en-Y Gastric Bypass
Intervention: Drug: venlafaxine ER (extended-release) 75 mg
Outcome Measure: Venlafaxine levels pre- and post-gastric bypass
4 Recruiting ADAPT: Addressing Depression and Pain Together
Conditions: Depression;   Back Pain
Interventions: Other: Combination Treatment with Higher-dose venlafaxine + PST-DP;   Drug: Higher-dose venlafaxine and supportive management
Outcome Measures: Depression: Patient Health Questionnaire-9;   Pain: 20-Point Numeric Rating Scale;   Self-Efficacy: Chronic Pain Self-Efficacy Scale
5 Recruiting Quality of Life Study Using Gabapentin Versus Venlafaxine in Treating Hot Flashes in Patients With Prostate Cancer
Condition: Hot Flashes in Men With Prostate Cancer Receiving Androgen Ablation Therapy
Interventions: Drug: Gabapentin;   Drug: Venlafaxine
Outcome Measures: Changes in quality of life;   compare toxicity rates between the gabapentin and venlafaxine treatment groups;   Assess changes in the hot flash scores for the two arms;   Assess changes in quality of life using the Hot flash related Daily Interference Scale (HFRDIS)
6 Recruiting Effectiveness Study to Compare Venlafaxine With Fluoxetine in the Treatment of Postmenopausal Women With Major Depression
Condition: Major Depression
Intervention: Drug: venlafaxine,fluoxetine
Outcome Measures: change of 24-item Hamilton Rating Scale for Depression total score;   the mean change of HAMD-24 subscale score in items 10, 11, 12, 13 (anxiety and somatizations) at endpoint
7 Recruiting Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six Weeks
Condition: Major Depressive Disorder
Interventions: Drug: ketamine venlafaxine;   Drug: Venlafaxine
Outcome Measure: Depressive state
8 Recruiting The HELP PAIN Trial
Condition: Neck Pain
Intervention: Drug: Venlafaxine
Outcome Measures: Average neck pain;   Chronic neck pain
9 Recruiting Venlafaxine for Depression in Alzheimer's Disease (DIADs-3)
Conditions: Alzheimer's Disease;   Depression
Interventions: Drug: Placebo;   Drug: Venlafaxine
Outcome Measures: 225 mg daily dose of venlafaxine over 12 weeks will produce changes in response on the modified AD Cooperative Study-Clinical Global Impression of Change and the Cornell Scale for Depression in Dementia.;   Examine in a proof of concept, 12-week randomized controlled trial, the safety of venlafaxine at a target dose of 225 mg daily for the treatment of Depression in patients with AD.
10 Not yet recruiting Beta-arrestins and Response to Venlafaxine in Major Depressive Disorder (MDD) (DEPARRESTCLIN)
Conditions: Major Depressive Disorder;   Major Depressive Episode
Intervention: Drug: Venlafaxine extended release
Outcome Measure: Change from baseline in depressive symptoms on the Hamilton Depression Rating Scale-17 items
11 Recruiting Venlafaxine Augmentation in Treatment Resistant Depression
Condition: Depression
Interventions: Drug: Venlafaxine;   Drug: Quetiapine
Outcome Measures: Hamilton Depression Rating Scale (HDRS);   Self reported psychopathology (Beck Depression Inventory [BDI], State-Trait Anxiety Inventory [STAI]);   Cognitive function
12 Unknown  Hippocampal Volume in Young Patients With Major Depression Before and After Combined Antidepressive Therapy
Condition: Depressive Disorder, Major
Interventions: Drug: Mirtazapine;   Drug: Venlafaxine
Outcome Measures: Categorial response to the medication. Categorial response is defined on the basis of CGI Improvement scale and 50% reduction in MADR-S score;   Tolerability of treatment as assessed using the DOTES scale;   Cognitive deficits as judged by the SKT system;   Self assessment of depression and anxiety using Beck's Depression/Anxiety Inventory (BDI/BAI);   Changes is blood levels of homocysteine, folate, vit B12, P11
13 Unknown  Pharmacogenomics Studies of Antidepressants
Conditions: Major Depressive Disorder;   Antidepressive Agents;   Pharmacogenetics;   Venlafaxine;   Fluoxetine
Interventions: Drug: Venlafaxine;   Drug: Fluoxetine
Outcome Measures: Hamilton Depression Rating Scale (HDRS);   C-reactive Protein and IL-6;   fasting blood glucose, lipid profiles
14 Recruiting International Study to Predict Optimised Treatment - in Depression
Condition: Major Depressive Disorder
Interventions: Drug: Escitalopram;   Drug: Sertraline;   Drug: Venlafaxine XR
Outcome Measures: To determine whether the genetic-brain-cognition function markers (or combination of markers) 'normalise' with acute drug treatment in MDD;   To determine whether markers of acute treatment prediction are also predictive of functional outcome over 6-12 months.
15 Recruiting A Study of Sustained-Release Desvenlafaxine Hydrochloride for the Treatment of Major Depressive Disorder
Condition: Major Depressive Disorder
Interventions: Drug: Sustained-Release Desvenlafaxine Hydrochloride;   Drug: Sustained-Release Venlafaxine Hydrochloride
Outcome Measures: Change From Baseline on the Hamilton Rating Scale for Depression, 17-item Total Score (HAM-D17);   Change From Baseline on the Clinical Global Impression Scale;   Change From Baseline in Clinical Global Impression-Improvement (CGI-I) Scale;   Change From Baseline in Sheehan Disability Scale (SDS) Total Score at Week 10;   Change From Baseline in Adjusted Mean on Montgomery-Asberg Depression Rating Scale (MADRS);   Change From Baseline on the Visual Analogue Scale-Pain Intensity (VAS-PI);   Number of Participants in Remission Based on the HAM-D17 at Week 10
16 Unknown  Treatment of Mild to Moderate Depression Symptoms in Patients With Spinal Cord Injury
Condition: Spinal Cord Injury
Interventions: Drug: Venlafaxine HCI;   Other: Placebo
Outcome Measures: The Patient Health Questionnaire-9 (PHQ-9);   The Beck Scale for Suicide Ideation (BSS);   16 item Quick Inventory of Depressive Symptomatology (QIDS- SR16);   The SCI Pain Instrument (SCIPI);   The Adherence and Side Effects Checklist;   CAGE & Drug Use;   Generalized Anxiety Disorder-7 (GAD-7);   The Perceived Stress Scale (PSS);   Life Experiences Survey - Disability (LES-D);   The Received Social Support and Social Undermining Scale (RSS/SU);   Measure of the Quality of the Environment;   The Perceived Handicap Questionnaire (PHQ);   Craig Handicap Assessment and Reporting Form - Short Form (CHART-SF);   The SF-12 Health Status Questionnaire - 12
17 Unknown  Electroencephalography (EEG) Signal Processing
Condition: Major Depressive Disorder
Interventions: Drug: Venlafaxine;   Drug: bupropion;   Drug: escitalopram;   Other: Psychotherapy;   Drug: Duloxetine
Outcome Measure: Machine learning
18 Recruiting Efficacy of Repetitive Transcranial Magnetic Stimulation in the Prevention of Relapse of Depression
Condition: Depression
Interventions: Procedure: repetitive Transcranial Magnetic Stimulation (rTMS);   Behavioral: counseling
Outcome Measures: Time for relapse;   Hamilton Depression Rating Scale;   Illness severity change;   subject functioning
19 Recruiting Prolonging Remission in Depressed Elderly (PRIDE)
Condition: Depression
Interventions: Drug: lithium and Venlafaxine;   Procedure: ECT
Outcome Measures: Long-term antidepressant efficacy (Hamilton Rating Scale for Depression);   Level of functioning (SF-36);   Tolerability (Mini Mental State Examination [MMSE]);   Tolerability (California Verbal Learning Test [CVLT-II], Autobiographical Memory Interview-Short Form [AMI-SF]);   Tolerability (Trail Making Tests, DRS-IP and Delis-Kaplan Executive Function System, Verbal Fluency;   Safety (Udvalg for Kliniske Undersogelser [UKU] Side Effects Rating Scale)
20 Recruiting Predict Antidepressant Responsiveness Using Pharmacogenomics
Conditions: Depression;   Depressive Symptoms
Interventions: Drug: SSRI class antidepressant;   Drug: non-SSRI class antidepressant
Outcome Measure: Presences of each individual symptom of depression at 1,2,4,6,12 weeks