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ACUTE KIDNEY INJURY and Amitriptyline

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ACUTE KIDNEY INJURY Symptoms and Causes

You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters. It goes to your bladder, which stores the urine until you go to the bathroom.

Most kidney diseases attack the nephrons. This damage may leave kidneys unable to remove wastes. Causes can include genetic problems, injuries, or medicines. You have a higher risk of kidney disease if you have diabetes, high blood pressure, or a close family member with kidney disease. Chronic kidney disease damages the nephrons slowly over several years. Other kidney problems include

  • Cancer
  • Cysts
  • Stones
  • Infections

Your doctor can do blood and urine tests to check if you have kidney disease. If your kidneys fail, you will need dialysis or a kidney transplant.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Check out the latest treatments for ACUTE KIDNEY INJURY

ACUTE KIDNEY INJURY treatment research studies

Amitriptyline clinical trials, surveys and public health registries


Find Drug Side Effect reports



Amitriptyline Side Effects

Completed Suicide (98)
Toxicity To Various Agents (72)
Overdose (61)
Cardiac Arrest (57)
Somnolence (48)
Pain (47)
Convulsion (45)
Anxiety (44)
Headache (44)
Death (42)
Confusional State (40)
Vomiting (40)
Dizziness (39)
Intentional Overdose (39)
Dyspnoea (38)
Loss Of Consciousness (38)
Nausea (35)
Fatigue (35)
Coma (33)
Respiratory Arrest (33)
Depression (32)
Hypotension (31)
Agitation (31)
Hallucination (29)
Malaise (29)
Fall (28)
Cardio-respiratory Arrest (28)
Syncope (27)
Diarrhoea (26)
Insomnia (26)
Tremor (26)
Pyrexia (25)
Grand Mal Convulsion (25)
Delirium (24)
Asthenia (24)
Abdominal Pain (23)
Feeling Abnormal (23)
Suicide Attempt (23)
Dysarthria (22)
Depressed Level Of Consciousness (21)
Constipation (21)
Deep Vein Thrombosis (21)
Electrocardiogram Qt Prolonged (21)
Serotonin Syndrome (21)
Palpitations (21)
Weight Decreased (20)
Gait Disturbance (20)
Dry Mouth (19)
Metabolic Acidosis (19)
Rash (19)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

im on amitriptyline 25mg,i have my xmas party this weekend and wanted to drink alchol. i wonder is it a good idea

After having been on elavil for 9 years, mostly at 100mg/night, I spent the last 6 months weaning off. Shortly after stopping amitriptyline I now have high blood pressure. Before stopping, and for years before starting, my usual pressure was 115/65,

Be safe !!

Been on amitrip 25mg at night for 8 nights now and have felt and look alot better. although i have diarrihea now and felt abit of nausea here and there . feel a tad tired throughout the day but i think for me the postives outweigh

Can amitriptyline can cause thrombocytopenia ?

Doc gave me 25mg to help me sleep after quitting the weed. not as good as zoplicone though

Does Amtriptyline help tinnitus. I'm taking it at a low dose for jaw problems and fibromyalgia. the 25 mg dose seems to make my tinnitus worse but my pain better. I don't know what to do?

For the past 18 mnths myfifteen year old takes Pizotifen for migraine.Even on low dose it hasvirtually seen off the migraine episodes and apart from initial tiredness for the first few weeks on it, we are not aware of an

Hey i took 500mg of amitriptyline and overdosed and almost Died.. Dont take that much

I have been taken 2 25mg at night for 6 months my mouth is dry all the time i carry water with me everywhere , i have a bloted tummy all the time ! but i die as soon as my head touches the pillow !!i feel fat all the time !!

<span style='color: #808080;'><b>Describe Your Injection site swelling from INFLUENZA (H1N1) (H1N1 (MONOVALENT) (UNKNOWN)) 2010 Experience Here: I am 46, Female on discharge from hospital 12.6.10 10pm after treatment for acute diverticuli

<span style='visibility: visible;'><span style='visibility: visible;'>After battling with acute insomnia for about 3 months, my GP prescribed Trimipramine 25mg. This still didn't get me much sleep, so he prescribed Purata 30mg. Better, bu

5th Week of Champix, so not smoked now for 3 weeks. Have experienced really bad headaches, mainly in the eyes, like acute sinisitus, will have to go to doctors to see if being caused by champix. Hope I do not have to come off them

Acute lower back pain causing lack of mobility?

Acute psychosis

Acutecontinuous incontinence

After 10 days of taking Aclasta serum 5mg i had all the side effects and after 10 days i still have chills and bone pain, what should i do? By the way im having a blood test tomorrow to know about the kidney,liver and glucose. so what should i do??

After a urinalisis the doctor told me there were no white blood cells, only red blood cells in urine. drew blood and had cat scan and revealed a 7mm kidney stone. but i'm worried about having no white blood cell count in my urine

After prolonged use my mother had kidney failier.DR did not want to point a finger but 1 took me aside and said Please do something I cannot.Do not use Metamucil orginal texure for a prolonged period.she used it for a long time and now theres no moth

After the kidney transplant my daughter's glucouse level was very high due to tacrolimus At the moment she takes insulin I want to know that the damage tacrolimus was done for the beta cells are permanant? little by little the units she takes reducin

ACUTE KIDNEY INJURY Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Amitriptyline to Prevent Headache After Traumatic Brain Injury
Conditions: Brain Injuries;   Post-Traumatic Headache
Intervention: Drug: Amitriptyline
Outcome Measures: Frequency and severity of headaches;   Headache Impact Test - 6;   Rivermead Post-Concussion Symptoms Questionnaire (RPQ);   Short Form-12® Health Survey (SF-12);   Number of participants with adverse events;   Headache characteristic survey;   Insomnia Severity Index;   Patient Health Questionnaire-9 (PHQ-9;   Rey Auditory Verbal Learning Test;   Trail Making Test;   Wechsler Adult Intelligence Scale (WAIS) IV Digit Symbol
2 Recruiting Trial of Amitriptyline for Chronic Oral Food Refusal in Children 9 Months to 8 Years of Age
Condition: Chronic Oral Food Refusal
Interventions: Drug: Amitriptyline 1 mg/kg;   Drug: Placebo
Outcome Measures: To assess the efficacy of Amitriptyline in a 24-week outpatient multi-disciplinary protocol for transitioning children from tube to oral feeding;   To assess the role of pain in the efficacy of Amitriptyline in the 24-week outpatient multidisciplinary protocol.
3 Unknown  Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy
Conditions: Herniated Disc;   Intervertebral Disc Displacement
Intervention: Drug: Gabapentin , Amitriptyline
Outcome Measures: 30% reduction in opium consumption in either study arms compared to the placebo group;   30% reduction in pain according to visual analogue scale in either study arms compared to the placebo group
4 Unknown  Amitriptyline or Pregabalin to Treat Neuropathic Pain in Incurable Cancer
Conditions: Cancer;   Neuralgia
Interventions: Drug: Amitriptyline;   Drug: pregabalin
Outcome Measures: VAS score;   EQ-5D, McGill, EORTC-C30, HADS
5 Unknown  Study With Amitriptylin to Evaluate the Efficacy of Melatonin in Treatment of Migraine
Condition: Migraine
Interventions: Drug: Amitriptyline;   Drug: Melatonin;   Drug: Placebo
Outcome Measures: Change in number of headache days from baseline to month 3 after treatment.;   Proportion of patients responding to treatment. Change from Baseline Phase to Double-Blind Phase in number of monthly migraine attacks,monthly migraine days, number of days/month requiring rescue medication.
6 Recruiting The Childhood and Adolescent Migraine Prevention Study
Conditions: Migraine;   Migraine Disorders;   Headache
Interventions: Drug: Amitriptyline;   Drug: Topiramate;   Drug: Placebo
Outcome Measures: Reduction in Migraine Frequency (Amitriptyline and topiramate);   Reduction in absolute migraine disability score on PedMIDAS;   Safety and tolerability of Amitriptyline and topiramate;   Occurrence of treatment-emergent serious adverse events;   Reduction in absolute migraine frequency days
7 Not yet recruiting Prediction of Migraine Prevention Efficacy: Individualization of Treatment by Coupling Drug's Mode of Action With Patient's Mechanism of Pain Modulation
Conditions: Migraine;   Preventive Treatment
Interventions: Drug: Amitriptyline;   Drug: placebo
Outcome Measures: the association between pre-treatment assessment parameter(s) and the reduction in frequency of migraine attacks by Amitriptyline;   the association between pain-related psychological parameters and the reduction in migraine attacks by Amitriptyline
8 Unknown  Anti-inflammatory Pulmonal Therapy of Cystic Fibrosis (CF) Patients With Amitriptyline and Placebo
Conditions: Cystic Fibrosis;   Pneumonia
Interventions: Drug: Amitriptyline;   Drug: Mannite
Outcome Measures: Improvement of the lung function parameter FEV1 (absolute and relative to baseline) under verum and placebo;   Increase in lung function measurements;   Ceramide concentration in epithelial cells;   Inflammation status;   Bacteriological and cell status;   Side effects
9 Recruiting Safety and Efficacy Study Comparing ETS6103 With Amitriptyline in the Treatment of Major Depressive Disorder (MDD)
Condition: Major Depressive Disorder
Interventions: Drug: ETS6103 (low dose);   Drug: ETS6103 (high dose);   Drug: Amitriptyline
Outcome Measures: The mean difference in baseline-adjusted (Montgomery-Asberg Depression Scale) MADRS score at the end of treatment.;   Assessment of MADRS score throughout the randomised study period;   Assessment of Clinical Global Impression (CGI) of Severity / Improvement Scale
10 Recruiting Alternative Dosing Regimens in the Pharmacotherapy of Insomnia
Condition: Insomnia
Interventions: Drug: Amitriptyline;   Drug: Zolpidem;   Drug: Placebo
Outcome Measures: Objective Total Sleep Time;   Objective Sleep Onset Latency;   Self-reported Total Sleep Time;   Self-Reported Sleep Onset Latency;   Percentage of REM sleep;   REM onset latency;   Objective Sleep Efficiency;   Self-Reported Total Sleep Time;   Self-reported Sleep Onset Latency (min);   Self-reported Sleep Onset Latency (evaluation)
11 Unknown  A Study to Compare the Pharmacokinetic Profiles of Etravil® Tablet 10mg and Etravil® Tablet 25mg
Condition: Depression
Interventions: Drug: Etravil 10mg Tablet;   Drug: Etravil 25mg Tablet
Outcome Measures: Cmax of Amitryptiline in plasma;   AUClast of amityptyline in plasma;   Tmax of amityptyline in plasma;   terminal half-life (t1/2) of amityptyline in plasma;   CL/F of amityptyline in plasma
12 Recruiting Effect of Minocycline on Pain Caused by Nerve Damage
Condition: Neuropathic Pain Caused by Lumbar Radicular Pain
Interventions: Drug: Minocycline;   Drug: placebo;   Drug: Amitriptyline
Outcome Measures: Pain intensity;   neuropathic pain diagnostic questionnaire (DN4) score;   Amount of rescue medication taken
13 Recruiting Immune-Pineal Axis Function in Fibromyalgia
Condition: Fibromyalgia
Interventions: Drug: Melatonin and Placebo;   Drug: Amitriptyline and Placebo;   Drug: Melatonin and Amitriptylin
Outcome Measures: Change from Baseline in pain on Fibromyalgia Impact Questionnaire (FIQ) at week 6;   Change from Baseline in Pain Pressure Threshold (PPT) at week 6;   Change from Baseline Brain-derived neurotrophic factor at week 6;   Change from Baseline of the Pittsburgh Sleep Quality Index (PSQI) at week 6;   Change from Baseline of the Pain Catastrophizing Scale at week 6
14 Unknown  Tricyclic Antidepressants (TCAs) on Gastric Emptying
Condition: Functional Dyspepsia
Interventions: Drug: Desipramine;   Drug: Amitriptyline
Outcome Measures: Gastric emptying;   Gastric volume
15 Recruiting Interpersonal Psychotherapy for Treatment Resistant Depression
Condition: Treatment Resistant Depression
Interventions: Other: IPT+ antidepressant drugs;   Drug: fluoxetine;   Drug: sertraline;   Drug: paroxetine;   Drug: Citalopram;   Drug: escitalopram;   Drug: fluvoxamine;   Drug: Venlafaxine;   Drug: Duloxetine;   Drug: Bupropion;   Drug: Lithium;   Drug: Risperidone;   Drug: tranylcypromine;   Drug: Imipramine;   Drug: Amitriptyline;   Drug: Clomipramine;   Drug: nortriptyline;   Drug: trazodone;   Drug: Mirtazapine;   Drug: sulpiride
Outcome Measures: Hamilton Depression Scale (HAM-D) - continuous;   Beck depression Inventory (BDI)
16 Recruiting Open Label Pharmacokinetic-Pharmacogenetic Study on Polymorphisms in the Organic Cation Transporter OCT1
Conditions: Drug Metabolism;   Membrane Transport
Interventions: Drug: Drug application Amitriptyline;   Drug: Drug application Desvenlafaxine;   Drug: Drug application Sumatriptan;   Drug: Drug application Proguanil
Outcome Measures: Area under the plasma concentration-time curve (AUC) of the investigational drugs;   Total clearance, Cmax, Tmax, Mean AbsorptionTime, Alpha and Beta half-lives, Mean Residence Time (MRT) and Volume of distribution of the investigated drugs and their metabolites;   Dry mouth, fatigue, nausea, headache, vertigo, tinnitus, chills, anxiety and difficulties to read on Visual Analog Scales.;   Sedation on Stanford sedation scale;   Pupil diameter, latency, diameter at maximal constriction, amplitude and time for 33% recovery of initial pupil diameter measured by pupillometrie;   Genetic variants in OCT1, CYP2C19, CYP2D6 and MAO A
17 Recruiting Pharmacological Conditioning of Sleep Patterns in Healthy Participants Using Amitriptylin
Condition: Healthy Participants
Interventions: Drug: Amitriptyline;   Drug: Placebo
Outcome Measures: Objective Total Sleep Time;   Percentage of rapid eye movement (REM) sleep
18 Unknown  Lidocaine on Pain Relief and IL and Substance P in Fibromyalgia
Condition: Fibromyalgia
Interventions: Drug: Lidocaine;   Drug: lidocaine
Outcome Measure: Evaluation of the effect of intravenous lidocaine on pain relief and plasma concentrations of interleukins (IL-1 and IL-6) and substance P in patients with fibromyalgia
19 Recruiting Cyclobenzaprine Extended Release (ER) for Fibromyalgia
Conditions: Fibromyalgia;   Pain;   Sleep;   Fatigue
Interventions: Drug: cyclobenzaprine ER (AMRIX);   Drug: placebo
Outcome Measures: Visual Analogue Pain Scale;   Brief Fatigue Inventory;   Analogue sleep/wakefulness scale;   Fibromyalgia Impact Questionnaire;   Sheehan Disability SCale;   Quick Inventory of Depression;   Reported Adverse Effects
20 Unknown  A Comparative Study Between Lysine Clonixinate+Cyclobenzaprine and Caffeine+Carisoprodol+Sodium Diclofenac+Paracetamol
Condition: Low Back Pain
Interventions: Drug: Tandrilax;   Drug: Dolamin Flex
Outcome Measures: Pain average reduction;   Identification of possible gastrointestinal effects