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AGITATION and Gabapentin

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AGITATION Symptoms and Causes

Caring for someone who has Alzheimer's disease (AD) can be stressful and overwhelming. It's important to take care of yourself. Ask for and accept help.

Talk to the doctor. Find out what treatments might help control symptoms or address behavior problems. Find a support group. Others who have "been there" may be able to help and will understand.

If there are times of day that the person is less confused or more cooperative, take advantage of that in daily routines. Consider using adult day care or respite services. These offer a break with the peace of mind that the patient is being taken care of. Begin to plan for the future. This may include

  • Getting financial and legal documents in order
  • Looking into assisted living or nursing homes
  • Finding out what your health insurance and Medicare will cover

NIH: National Institute on Aging

Check out the latest treatments for AGITATION

AGITATION treatment research studies

Gabapentin clinical trials, surveys and public health registries


Find Drug Side Effect reports



Gabapentin Side Effects

Completed Suicide (332)
Dizziness (329)
Somnolence (304)
Pain (286)
Headache (273)
Confusional State (257)
Nausea (248)
Off Label Use (227)
Tremor (214)
Depression (214)
Fatigue (212)
Fall (194)
Convulsion (183)
Feeling Abnormal (181)
Toxicity To Various Agents (173)
Suicidal Ideation (166)
Malaise (165)
Respiratory Arrest (163)
Cardiac Arrest (145)
Condition Aggravated (144)
Dyspnoea (113)
Pain In Extremity (112)
Myoclonus (108)
Anxiety (108)
Asthenia (107)
Amnesia (104)
Diarrhoea (102)
Insomnia (97)
Vision Blurred (90)
Gait Disturbance (85)
Vomiting (84)
Death (84)
Oedema Peripheral (83)
Disorientation (82)
Back Pain (80)
Rash (80)
Weight Increased (79)
Agitation (78)
Paraesthesia (74)
Memory Impairment (73)
Dyskinesia (73)
Abdominal Pain (73)
Hallucination (72)
Muscular Weakness (71)
Sedation (71)
Myalgia (70)
Loss Of Consciousness (70)
Renal Failure Acute (69)
Hypoaesthesia (66)
Muscle Spasms (66)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

Be careful! Avoid Gabapentin at all costs! My mother's doctor ordered a 900 mg/day dose. In the 2 years she was under this dose, she fell 5 times! No doctor 'suspected' this drug! Then, he increased the dose to...1800 mg/day! I almost lost her! I am

Dose Gabapantin have any ting to do with the nearves in your body

For the last two weeks I have been taking a lowish dose of Gabapentin for night-time nerve pain (100gm three times a day and then 200mg at night.) It has worked brilliantly for the pain and I was ecstatic BUT I have now wet the bed two nights in a r

GABAPENTIN noticed that medication got worsen n Nurgloist n don't listin. My problem n even rash n stomach ach n was getting stress out n decided go different doctor n was. Going take that chance with my n stop going to Nurgloist n been two.n bo

Great so far for my anxiety... just side effects has ... sexually saticfied,nausea little bit.. dizzynezz! lolz.. but great medication/ i think..

Having racing thoughts and unmotivated *DONT_KNOW*

Hear voices

Hello, I've been taking a cocktail of meds for 9 years to help treat acute nerve pain from a severe Brachial Plexus nerve avulsion C 7, 8, T1 and Spinal cord injury. Medications: Gabapentin 3600 mg., Methadone 100 mg. , Baclofen 20 mg. every 8 hour

I am having trouble falling to sleep, and I feel like I' having anxiety attacks I stopped the 400 Mg and I am taking 2 100 MGS now. I am doing this on my own , until I see my Dr next week. .

I am just starting Gabapentin to help with phantom pain from a BKA (below-knee-amputation). I am taking 600 mg and am scheduled to increase to 900 mg, then review results with my doctors. One of the side effects I seem to have is

Agitation and sleeplessness

C.onstipation terribly. Agitation, depression. It may be opening my lungs for better breathing (not sure), oh!, and vision problems paramount, but it is just a horrible drug. I am quiitting for a while and see what happens after having been on it

Found amisulpride to be the best tolerated drug at a low dose out of the three anti-psychotics i had tried. Higher doses lead to agitation and depression. Iam on 50mg and feel no side affects. But I found the most remarkable affect on my symptoms (he

Heart palpitations, high blood pressure, insomnia, agitation, hair loss. Used the 4 mg tablets, 6 to 10 per day for about 13 mos. Quitting was not difficult, drank lots of water everyday to clearn out my system.

Hi, i have recently come off venlafaxine after 7 years and after a recent spell in hospital i was prescribed remeron/mirtazipine. things were ok for about two weeks but now i am experiencing high levels of agitation, panic and and an extremly unpl

I am taking Solian 200mg a night for the last 7 years. I feel really lazy and just can't wake up early in the morning. I feel really agitation, depressedand anxiety sometimes.Solian seems to be a lot

I expereinced folloing S/E - Stomach upset, Parasthesia, Insomnia, Agitation and loss of concentration since last 3 days of taking first dose.

I have been on Aurorix for 6 months now, I have sleep disorders, cant sleep, when I do I wake up with itching hands and feet. My agitation, anxiety, panic attacks, despair, wanting to just die are increasing. Increasing medication seems to just aggra

I have been taking Zeldox for the past 4 days, switching from Zyprexa because of weight gain. I am in an extreme state of agitation and anxiety with deep negative thoughts. I also take methadone so I can't use any benzos. My doctor is on vacation and

I have got severe agitation as a result of the depot. It' ruining my life.

AGITATION Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Stress Biomarkers Among Patients Undergoing Treatment for Excited Delirium and Severe Pain in the Emergency Department
Conditions: Agitation;   Excited Delirium;   Pain
Intervention:
Outcome Measures: Change in Altered Mental Status Score;   Change in Visual Analog Scale Pain Score;   Change in Serum Total Catecholamines;   Length of Hospital Stay;   Mortality;   Complications;   Change in Heart Rate;   Change in Systolic Blood Pressure;   Change in Mean Arterial Pressure;   Disposition;   Change in Body Temperature;   Change in end tidal carbon dioxide;   Change in Oxygen Saturation
2 Not yet recruiting Effect of Deksmedetomidine and Remifentanil in Extubation Agitation
Condition: Agitation
Interventions: Drug: deksmedetomidine;   Drug: Remifentanil;   Drug: Saline
Outcome Measures: To asses postoperative Agitation score by Riker sedation Agitation scale;   Yo asses postoperative side effects emesis, vomitting or pain
3 Not yet recruiting Ketamine Versus Haloperidol for Severe Agitation Outside the Hospital
Condition: Agitation
Interventions: Drug: Ketamine;   Drug: Haloperidol
Outcome Measures: Time from injection of drug to adequate sedation, defined as a score of 0 or less on the AMSS.;   Number of participants intubated.;   venous pH;   serum potassium;   Total time the participant is a patient in the Emergency Department.;   Number of patients admitted versus number of patients discharged.;   venous lactate;   Number of patients experiencing laryngospasm.;   Number of patients experiencing dystonia.
4 Recruiting Safety and Tolerability Study of Flexible Dosing of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type
Conditions: Agitation Associated With;   Alzheimer's Disease;   Alzheimer's Type;   Mental Disorder;   Nervous System Diseases
Intervention: Drug: Brexpiprazole, OPC-34712
Outcome Measures: Change in the Cohen-Mansfield Agitation Inventory (CMAI) total score;   Change in the Clinical Global Impression Severity of Illness (CGI-S) score, as related to symptoms of Agitation
5 Recruiting A Study of Three Fixed-doses of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type
Conditions: Agitation Associated With;   Alzheimer's Disease;   Alzheimer's Type;   Mental Disorder;   Nervous System Diseases
Intervention: Drug: Brexpiprazole, OPC-34712
Outcome Measures: The primary outcome is the change in the Cohen-Mansfield Agitation Inventory (CMAI) total score;   The secondary outcome is the change in the Clinical Global Impression-Severity of Illness (CGI-S) score, as related to symptoms of Agitation
6 Unknown  Pre-hospital Agitation and Sedation Trial: A Randomized Controlled Trial of Haloperidol Versus Midazolam for the Sedation of the Agitated Patient
Condition: Agitation
Interventions: Drug: Haloperidol;   Drug: Midazolam
Outcome Measure: Time to sedation
7 Recruiting Dexmedetomidine to Prevent Agitation After Free Flap Surgery
Conditions: Agitation;   Delirium
Interventions: Drug: Dexmedetomidine;   Drug: Saline placebo
Outcome Measures: Agitation in PACU;   postoperative delirium
8 Unknown  Treatment Routes for Exploring Agitation
Conditions: Dementia;   Behavior Problems
Interventions: Behavioral: TREA (Treatment Routes for Exploring Agitation);   Behavioral: Placebo Control Group
Outcome Measures: Agitation Behavior Mapping Instrument (ABMI);   affect/mood measured by Lawton's behavior stream assessment
9 Not yet recruiting Vasculaire Leg Compression Device for the Treatment of Restless Legs Syndrome - A Prospective Clinical Study
Conditions: Restless Legs Syndrome,;   Restless Legs,;   Ekbom Syndrome
Intervention: Device: Venous Health Systems Vasculaire Leg Compression Device
Outcome Measures: The Restless Legs Syndrome Rating Scale;   The Restless Legs Syndrome-Quality of Life Instrument (RLS-QLI);   The Epworth Sleepiness Scale (ESS);   The Johns Hopkins Restless Legs Severity Scale (JHRLS);   The International Restless Legs Syndrome Rating Scale
10 Recruiting Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?
Conditions: Emergence Agitation;   Pain
Intervention: Drug: Acetaminophen
Outcome Measures: Emergence Agitation;   Pain
11 Unknown  The Effect of Intramuscular Dexmedetomidine on Emergence Agitation in Children Undergoing With or Without Tube Insertion Under General Anesthesia
Condition: Myringotomy
Intervention: Drug: Dexmedetomidine
Outcome Measures: Participant's Severity of Emergent Agitation (EA) using the Pediatric Anesthesia Emergence Delirium (PAED) scale in PACU (Post-Op Area).;   Participant's Severity of Emergent Agitation (EA) in PACU (Post-Op Area) through Day 3 Post-Op using the Postanesthesia Discharge Scoring System (PADSS) score.;   Participant's Severity of Emergent Agitation (EA) in PACU (Post-Op Area) through Day 3 Post-Op using the PADSS score.
12 Recruiting Reducing Agitation in People With Dementia: the Customized Activity Trial
Condition: Dementia
Interventions: Behavioral: Tailored Activity Program;   Other: Home Safety and Education Program
Outcome Measures: Frequency of Agitated Behavior in person with dementia;   Frequency of agitated behaviors and quality of life in person with dementia;   Caregiver wellbeing and time spent providing care;   Cost effectiveness
13 Unknown  IM Olanzapine Versus IM Haloperidol Plus Lorazepam for Acute Agitation in Schizophrenia
Conditions: Schizophrenia;   Schizoaffective Disorder;   Agitation
Interventions: Drug: IM olanzapine;   Drug: haloperidol plus lorazepam IM
Outcome Measures: Positive and Negative Symptom Scale Excited Component (PANSS-EC);   Agitation-Calmness Evaluation Scale (ACES)
14 Not yet recruiting Treatment of Psychosis and Agitation in Alzheimer's Disease
Conditions: Alzheimer's Disease;   Psychosis;   Agitation
Interventions: Drug: Lithium;   Drug: Placebo
Outcome Measures: Change in Neuropsychiatric Inventory (NPI) Score;   Clinical Global Impression (CGI) Global;   Clinical Global Impression (CGI) Behavior;   Young Mania Rating Scale;   Treatment Emergent Signs and Symptoms (TESS);   Simpson-Angus Scale;   Basic Activities of Daily Living (BADL);   Zarit Caregiver Burden Interview;   Clinical Dementia Rating Scale (CDR)
15 Unknown  ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children
Condition: Agitation
Intervention: Drug: Dexmedetomidine
Outcome Measures: Agitation;   pain
16 Unknown  The Effect of Dexmedetomidine on Emergence Agitation in Children Undergoing a Surgery Under Desflurane Anesthesia
Condition: Psychomotor Agitation
Interventions: Drug: Dexmedetomidine;   Drug: 0.9% Normal Saline
Outcome Measures: Agitation score;   Oculomotor reflex
17 Recruiting Efficacy and Safety Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease
Condition: Alzheimer's Disease
Interventions: Drug: ELND005;   Drug: Placebo
Outcome Measures: Change from Baseline in NPI-C combined Agitation and aggression subscores;   Change from Baseline in modified-ADCS-CGIC Agitation scores;   Change from Baseline in NPI total scores;   Change from Baseline in MMSE scores;   Change from Baseline in ADCS-ADL scores;   Incidence and severity of adverse events
18 Not yet recruiting A RCT of Compound Lidocaine Cream to Prevent Postoperative Agitation in Patients With Endotracheal Intubation for GA
Condition: Postoperative Agitation of Patients
Intervention: Drug: Compound Lidocaine Cream
Outcome Measures: Vital signs like blood pressure and heart rates during extubation.;   The cough reflex and breath holding during extubation.
19 Unknown  Multidisciplinary Intervention for Challenging Behaviour (Agitation) in Patients With Dementia
Condition: Dementia
Intervention: Behavioral: Psychosocial intervention
Outcome Measures: Agitation measured by the C-MAI (The Cohen-Mansfield Agitation Inventory);   The Cornell scale for depression in dementia (CSDD);   Neuropsychiatric Inventory (NPI ) which measures neuropsychiatric symptoms and behaviour;   Lawton's self-maintenance scale (Lawton and Brody 1969), which measures function in activities of daily living (ADL);   Quality of life in Alzheimers's Disease (QUALID) (Weiner et al. 2000), which measures quality of life;   Staff measures: Psychosocial factors in work life will be measured by a scale developed by Sund (1992).;   Use of antipsychotic drugs;   Staff measures:P-cat:Person-centered Care Assessment Tool
20 Unknown  Dexmedetomidine to Lessen Intensive Care Unit (ICU) Agitation
Condition: Delirium
Interventions: Drug: Dexmedetomidine;   Drug: Saline placebo
Outcome Measures: Ventilator-free hours;   Time to ICU discharge;   Overall ICU length of stay;   Time to first extubation;   Time taken to achieve a satisfactory sedation score;   %ICU time spent with a satisfactory sedation score;   %ICU time spent with a satisfactory delirium score;   Time taken to achieve a satisfactory Agitation score;   %ICU time spent with a satisfactory Agitation score;   Need for supplementary sedative medication;   Need for mechanical restraint;   Need for supplementary antipsychotic medication;   Need for tracheostomy;   Acute hospital length of stay;   Discharge destination;   Daily SOFA score;   ICU mortality;   Hospital mortality;   Duration and rate of vasopressor support;   Need for insertion of a new central venous catheter to facilitate vasopressor / inotropic support;   Requirement for reintubation