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BACK PAIN and Amitriptyline

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BACK PAIN Symptoms and Causes

If you've ever groaned, "Oh, my aching back!", you are not alone. Back pain is one of the most common medical problems, affecting 8 out of 10 people at some point during their lives. Back pain can range from a dull, constant ache to a sudden, sharp pain. Acute back pain comes on suddenly and usually lasts from a few days to a few weeks. Back pain is called chronic if it lasts for more than three months.

Most back pain goes away on its own, though it may take awhile. Taking over-the-counter pain relievers and resting can help. However, staying in bed for more than 1 or 2 days can make it worse.

If your back pain is severe or doesn't improve after three days, you should call your health care provider. You should also get medical attention if you have back pain following an injury.

Treatment for back pain depends on what kind of pain you have, and what is causing it. It may include hot or cold packs, exercise, medicines, injections, complementary treatments, and sometimes surgery.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Check out the latest treatments for BACK PAIN

BACK PAIN treatment research studies

Amitriptyline clinical trials, surveys and public health registries


Find Drug Side Effect reports



Amitriptyline Side Effects

Completed Suicide (98)
Toxicity To Various Agents (72)
Overdose (61)
Cardiac Arrest (57)
Somnolence (48)
Pain (47)
Convulsion (45)
Anxiety (44)
Headache (44)
Death (42)
Confusional State (40)
Vomiting (40)
Dizziness (39)
Intentional Overdose (39)
Dyspnoea (38)
Loss Of Consciousness (38)
Nausea (35)
Fatigue (35)
Coma (33)
Respiratory Arrest (33)
Depression (32)
Hypotension (31)
Agitation (31)
Hallucination (29)
Malaise (29)
Fall (28)
Cardio-respiratory Arrest (28)
Syncope (27)
Diarrhoea (26)
Insomnia (26)
Tremor (26)
Pyrexia (25)
Grand Mal Convulsion (25)
Delirium (24)
Asthenia (24)
Abdominal Pain (23)
Feeling Abnormal (23)
Suicide Attempt (23)
Dysarthria (22)
Depressed Level Of Consciousness (21)
Constipation (21)
Deep Vein Thrombosis (21)
Electrocardiogram Qt Prolonged (21)
Serotonin Syndrome (21)
Palpitations (21)
Weight Decreased (20)
Gait Disturbance (20)
Dry Mouth (19)
Metabolic Acidosis (19)
Rash (19)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

im on amitriptyline 25mg,i have my xmas party this weekend and wanted to drink alchol. i wonder is it a good idea

After having been on elavil for 9 years, mostly at 100mg/night, I spent the last 6 months weaning off. Shortly after stopping amitriptyline I now have high blood pressure. Before stopping, and for years before starting, my usual pressure was 115/65,

Back pain in my mid backafter 3-5 hrs of sleep, constant tossing and turning for rest of night.

Be safe !!

Been on amitrip 25mg at night for 8 nights now and have felt and look alot better. although i have diarrihea now and felt abit of nausea here and there . feel a tad tired throughout the day but i think for me the postives outweigh

Can amitriptyline can cause thrombocytopenia ?

Doc gave me 25mg to help me sleep after quitting the weed. not as good as zoplicone though

Does Amtriptyline help tinnitus. I'm taking it at a low dose for jaw problems and fibromyalgia. the 25 mg dose seems to make my tinnitus worse but my pain better. I don't know what to do?

For 7 months, I've been weak in my right leg with numbness in my right foot and hip. It's been so difficult moving around, so I don't go outside unless I have a medical appointment. Around May ending, after 8 months of pain and great anxiety, I recei

For the past 18 mnths myfifteen year old takes Pizotifen for migraine.Even on low dose it hasvirtually seen off the migraine episodes and apart from initial tiredness for the first few weeks on it, we are not aware of an

I took Beano (only one pill) last week and 2 hours later I ended up with a terrible stomach pain.I did not connect the dots, I suspected that it was caused by certain ingredients in the food I was eating. Itwas a very unique pain

Yesterday, after taking Sam-e with Glucosamine. I got a pain between my shoulder blade, jaw pain, dizziness, sweating. felt like a heart attack. I did not go to the hospital because of the money needed. No ins

<b><span style='font-weight: normal;'><b>After 6 weeks of oral lamisil I experienced</b>eczema, muscle weakness, asthma, bloody bowels, lower abdominal pain, dizziness, extreme f

63 yo man received Zostavax injection in the left upper arm 12/13/11. Developed painful blister on the right shoulder and pain at the right lower ribs 12/10/11.

After using Clobetasol for a two week cycle, my doctor suggested I use it one day during the week, applying it twice that day. Since that time, I have experinced severe chest pain. I recently saw my doctor for heart attack symptoms before I reali

Arthritis Treatment Safe, Natural Cure for Adults. Synflex Liquid Glucosamine, Rheumatoid Arthritis Joint Pain Relief Remedy, Diet Supplements. Synflex, Glucosamine for Dogs. Free Shipping! &lt;a href='http://www.healthyjointcare.com/'&g

Marax was the asthma the best medicine for me to treat asthma. Inhalers do not work. Apparently centuries of using the contents of Marax with success does not count with the FDA. Shame on them. Bring back this medication.

My father is 68 and retired, he is also diabetic. He suffers from severe joints, hip and back pain. He has been using panadol extra strength but finds it takes too long to act. He is also allergic to aspirin and was hospitalized with a ruptured u

My son was suffering from Head ache for the past one year. I have taken him to an ENT & he prescribed Sibelium 10 mg. & he was taking sibelium 3 months back for migraine and he was experiencing fatigue and drowsiness every day. Every t

While taking Pradaxa I had severe knife feeling pain in left eye. I have been off 2 days and it is better. I will check with eye docotr this week and see if it is eye or meds.

BACK PAIN Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Amitriptyline to Prevent Headache After Traumatic Brain Injury
Conditions: Brain Injuries;   Post-Traumatic Headache
Intervention: Drug: Amitriptyline
Outcome Measures: Frequency and severity of headaches;   Headache Impact Test - 6;   Rivermead Post-Concussion Symptoms Questionnaire (RPQ);   Short Form-12® Health Survey (SF-12);   Number of participants with adverse events;   Headache characteristic survey;   Insomnia Severity Index;   Patient Health Questionnaire-9 (PHQ-9;   Rey Auditory Verbal Learning Test;   Trail Making Test;   Wechsler Adult Intelligence Scale (WAIS) IV Digit Symbol
2 Recruiting Trial of Amitriptyline for Chronic Oral Food Refusal in Children 9 Months to 8 Years of Age
Condition: Chronic Oral Food Refusal
Interventions: Drug: Amitriptyline 1 mg/kg;   Drug: Placebo
Outcome Measures: To assess the efficacy of Amitriptyline in a 24-week outpatient multi-disciplinary protocol for transitioning children from tube to oral feeding;   To assess the role of pain in the efficacy of Amitriptyline in the 24-week outpatient multidisciplinary protocol.
3 Unknown  Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy
Conditions: Herniated Disc;   Intervertebral Disc Displacement
Intervention: Drug: Gabapentin , Amitriptyline
Outcome Measures: 30% reduction in opium consumption in either study arms compared to the placebo group;   30% reduction in pain according to visual analogue scale in either study arms compared to the placebo group
4 Unknown  Amitriptyline or Pregabalin to Treat Neuropathic Pain in Incurable Cancer
Conditions: Cancer;   Neuralgia
Interventions: Drug: Amitriptyline;   Drug: pregabalin
Outcome Measures: VAS score;   EQ-5D, McGill, EORTC-C30, HADS
5 Unknown  Study With Amitriptylin to Evaluate the Efficacy of Melatonin in Treatment of Migraine
Condition: Migraine
Interventions: Drug: Amitriptyline;   Drug: Melatonin;   Drug: Placebo
Outcome Measures: Change in number of headache days from baseline to month 3 after treatment.;   Proportion of patients responding to treatment. Change from Baseline Phase to Double-Blind Phase in number of monthly migraine attacks,monthly migraine days, number of days/month requiring rescue medication.
6 Recruiting The Childhood and Adolescent Migraine Prevention Study
Conditions: Migraine;   Migraine Disorders;   Headache
Interventions: Drug: Amitriptyline;   Drug: Topiramate;   Drug: Placebo
Outcome Measures: Reduction in Migraine Frequency (Amitriptyline and topiramate);   Reduction in absolute migraine disability score on PedMIDAS;   Safety and tolerability of Amitriptyline and topiramate;   Occurrence of treatment-emergent serious adverse events;   Reduction in absolute migraine frequency days
7 Not yet recruiting Prediction of Migraine Prevention Efficacy: Individualization of Treatment by Coupling Drug's Mode of Action With Patient's Mechanism of Pain Modulation
Conditions: Migraine;   Preventive Treatment
Interventions: Drug: Amitriptyline;   Drug: placebo
Outcome Measures: the association between pre-treatment assessment parameter(s) and the reduction in frequency of migraine attacks by Amitriptyline;   the association between pain-related psychological parameters and the reduction in migraine attacks by Amitriptyline
8 Unknown  Anti-inflammatory Pulmonal Therapy of Cystic Fibrosis (CF) Patients With Amitriptyline and Placebo
Conditions: Cystic Fibrosis;   Pneumonia
Interventions: Drug: Amitriptyline;   Drug: Mannite
Outcome Measures: Improvement of the lung function parameter FEV1 (absolute and relative to baseline) under verum and placebo;   Increase in lung function measurements;   Ceramide concentration in epithelial cells;   Inflammation status;   Bacteriological and cell status;   Side effects
9 Recruiting Safety and Efficacy Study Comparing ETS6103 With Amitriptyline in the Treatment of Major Depressive Disorder (MDD)
Condition: Major Depressive Disorder
Interventions: Drug: ETS6103 (low dose);   Drug: ETS6103 (high dose);   Drug: Amitriptyline
Outcome Measures: The mean difference in baseline-adjusted (Montgomery-Asberg Depression Scale) MADRS score at the end of treatment.;   Assessment of MADRS score throughout the randomised study period;   Assessment of Clinical Global Impression (CGI) of Severity / Improvement Scale
10 Recruiting Alternative Dosing Regimens in the Pharmacotherapy of Insomnia
Condition: Insomnia
Interventions: Drug: Amitriptyline;   Drug: Zolpidem;   Drug: Placebo
Outcome Measures: Objective Total Sleep Time;   Objective Sleep Onset Latency;   Self-reported Total Sleep Time;   Self-Reported Sleep Onset Latency;   Percentage of REM sleep;   REM onset latency;   Objective Sleep Efficiency;   Self-Reported Total Sleep Time;   Self-reported Sleep Onset Latency (min);   Self-reported Sleep Onset Latency (evaluation)
11 Unknown  A Study to Compare the Pharmacokinetic Profiles of Etravil® Tablet 10mg and Etravil® Tablet 25mg
Condition: Depression
Interventions: Drug: Etravil 10mg Tablet;   Drug: Etravil 25mg Tablet
Outcome Measures: Cmax of Amitryptiline in plasma;   AUClast of amityptyline in plasma;   Tmax of amityptyline in plasma;   terminal half-life (t1/2) of amityptyline in plasma;   CL/F of amityptyline in plasma
12 Recruiting Effect of Minocycline on Pain Caused by Nerve Damage
Condition: Neuropathic Pain Caused by Lumbar Radicular Pain
Interventions: Drug: Minocycline;   Drug: placebo;   Drug: Amitriptyline
Outcome Measures: Pain intensity;   neuropathic pain diagnostic questionnaire (DN4) score;   Amount of rescue medication taken
13 Recruiting Immune-Pineal Axis Function in Fibromyalgia
Condition: Fibromyalgia
Interventions: Drug: Melatonin and Placebo;   Drug: Amitriptyline and Placebo;   Drug: Melatonin and Amitriptylin
Outcome Measures: Change from Baseline in pain on Fibromyalgia Impact Questionnaire (FIQ) at week 6;   Change from Baseline in Pain Pressure Threshold (PPT) at week 6;   Change from Baseline Brain-derived neurotrophic factor at week 6;   Change from Baseline of the Pittsburgh Sleep Quality Index (PSQI) at week 6;   Change from Baseline of the Pain Catastrophizing Scale at week 6
14 Unknown  Tricyclic Antidepressants (TCAs) on Gastric Emptying
Condition: Functional Dyspepsia
Interventions: Drug: Desipramine;   Drug: Amitriptyline
Outcome Measures: Gastric emptying;   Gastric volume
15 Recruiting Interpersonal Psychotherapy for Treatment Resistant Depression
Condition: Treatment Resistant Depression
Interventions: Other: IPT+ antidepressant drugs;   Drug: fluoxetine;   Drug: sertraline;   Drug: paroxetine;   Drug: Citalopram;   Drug: escitalopram;   Drug: fluvoxamine;   Drug: Venlafaxine;   Drug: Duloxetine;   Drug: Bupropion;   Drug: Lithium;   Drug: Risperidone;   Drug: tranylcypromine;   Drug: Imipramine;   Drug: Amitriptyline;   Drug: Clomipramine;   Drug: nortriptyline;   Drug: trazodone;   Drug: Mirtazapine;   Drug: sulpiride
Outcome Measures: Hamilton Depression Scale (HAM-D) - continuous;   Beck depression Inventory (BDI)
16 Recruiting Open Label Pharmacokinetic-Pharmacogenetic Study on Polymorphisms in the Organic Cation Transporter OCT1
Conditions: Drug Metabolism;   Membrane Transport
Interventions: Drug: Drug application Amitriptyline;   Drug: Drug application Desvenlafaxine;   Drug: Drug application Sumatriptan;   Drug: Drug application Proguanil
Outcome Measures: Area under the plasma concentration-time curve (AUC) of the investigational drugs;   Total clearance, Cmax, Tmax, Mean AbsorptionTime, Alpha and Beta half-lives, Mean Residence Time (MRT) and Volume of distribution of the investigated drugs and their metabolites;   Dry mouth, fatigue, nausea, headache, vertigo, tinnitus, chills, anxiety and difficulties to read on Visual Analog Scales.;   Sedation on Stanford sedation scale;   Pupil diameter, latency, diameter at maximal constriction, amplitude and time for 33% recovery of initial pupil diameter measured by pupillometrie;   Genetic variants in OCT1, CYP2C19, CYP2D6 and MAO A
17 Recruiting Pharmacological Conditioning of Sleep Patterns in Healthy Participants Using Amitriptylin
Condition: Healthy Participants
Interventions: Drug: Amitriptyline;   Drug: Placebo
Outcome Measures: Objective Total Sleep Time;   Percentage of rapid eye movement (REM) sleep
18 Unknown  Lidocaine on Pain Relief and IL and Substance P in Fibromyalgia
Condition: Fibromyalgia
Interventions: Drug: Lidocaine;   Drug: lidocaine
Outcome Measure: Evaluation of the effect of intravenous lidocaine on pain relief and plasma concentrations of interleukins (IL-1 and IL-6) and substance P in patients with fibromyalgia
19 Recruiting Cyclobenzaprine Extended Release (ER) for Fibromyalgia
Conditions: Fibromyalgia;   Pain;   Sleep;   Fatigue
Interventions: Drug: cyclobenzaprine ER (AMRIX);   Drug: placebo
Outcome Measures: Visual Analogue Pain Scale;   Brief Fatigue Inventory;   Analogue sleep/wakefulness scale;   Fibromyalgia Impact Questionnaire;   Sheehan Disability SCale;   Quick Inventory of Depression;   Reported Adverse Effects
20 Unknown  A Comparative Study Between Lysine Clonixinate+Cyclobenzaprine and Caffeine+Carisoprodol+Sodium Diclofenac+Paracetamol
Condition: Low Back Pain
Interventions: Drug: Tandrilax;   Drug: Dolamin Flex
Outcome Measures: Pain average reduction;   Identification of possible gastrointestinal effects