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BACK PAIN and Baclofen

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BACK PAIN Symptoms and Causes

If you've ever groaned, "Oh, my aching back!", you are not alone. Back pain is one of the most common medical problems, affecting 8 out of 10 people at some point during their lives. Back pain can range from a dull, constant ache to a sudden, sharp pain. Acute back pain comes on suddenly and usually lasts from a few days to a few weeks. Back pain is called chronic if it lasts for more than three months.

Most back pain goes away on its own, though it may take awhile. Taking over-the-counter pain relievers and resting can help. However, staying in bed for more than 1 or 2 days can make it worse.

If your back pain is severe or doesn't improve after three days, you should call your health care provider. You should also get medical attention if you have back pain following an injury.

Treatment for back pain depends on what kind of pain you have, and what is causing it. It may include hot or cold packs, exercise, medicines, injections, complementary treatments, and sometimes surgery.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Check out the latest treatments for BACK PAIN

BACK PAIN treatment research studies

Baclofen clinical trials, surveys and public health registries


Find Drug Side Effect reports



Baclofen Side Effects

Overdose (180)
Coma (125)
Muscle Spasticity (122)
Pain (99)
Confusional State (96)
Muscle Spasms (94)
Convulsion (92)
Completed Suicide (92)
Fatigue (82)
Fall (77)
Somnolence (76)
Pyrexia (75)
Nausea (73)
Hypertension (73)
Dizziness (72)
Headache (70)
Death (70)
Vomiting (69)
Mental Status Changes (68)
Poisoning (68)
Pneumonia (66)
Hypotension (65)
Delirium (63)
Asthenia (62)
Bradycardia (62)
Neurotoxicity (62)
Agitation (60)
Urinary Tract Infection (59)
Dyspnoea (58)
Loss Of Consciousness (55)
Condition Aggravated (54)
Cardiac Arrest (52)
Intentional Overdose (51)
Hypotonia (49)
Implant Site Effusion (48)
Gait Disturbance (47)
Malaise (47)
Depressed Level Of Consciousness (46)
Multiple Sclerosis Relapse (45)
Respiratory Arrest (45)
Withdrawal Syndrome (45)
Medical Device Complication (44)
Hallucination (43)
Tremor (43)
Pain In Extremity (42)
Suicide Attempt (42)
Respiratory Failure (42)
Disorientation (40)
Muscular Weakness (39)
Toxicity To Various Agents (39)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

Alopecia areata

Back pain in my mid backafter 3-5 hrs of sleep, constant tossing and turning for rest of night.

For 7 months, I've been weak in my right leg with numbness in my right foot and hip. It's been so difficult moving around, so I don't go outside unless I have a medical appointment. Around May ending, after 8 months of pain and great anxiety, I recei

HELLO IAM STACEY HENDERSON,SORRY I PUT CAP'S JUST INCASE YOU COULDN'T READ IT I JUST WANTED TO ASK A QUESTION FOR MY DAD AS IAM VERY WORRIED HE'S BEEN SUFFERING WITH BACK PAIN ALL HIS LIFE AND I WOULD LIKE TO KNOW WHAT ARE THE SIDE EFFECTS FOR THE PA

Husbnd is a 15 yr. stroke survivor who had a baclofen pump since about 2001. It was replaced Nov. 2009 and nothing but trouble... passing out, weakness, falling, etc. 4 ER trips and not one dr. ever mentioned b

I had a devastating experience with this drug. I had been using Flexeril for back and neck pain but found it no longer as effective. I asked my doctor if there was something stronger. He prescribed Baclofen. Having not read the label carefully, m

I have experience hads spasm,diziness,headaches,shallow or hard breathing,slepiness,pain in the side (new)

I too had a nasty bite from baclofen.I had a craving for alcohol and was on 10 mg TID.I took 90mg at once. within one hour I feel like i was on shrooms! Very vivid CEVs(closed eyed visuals) and some ope eyed visuals(OEVs).Actually I enjoyed this.But

I'm 13 and since last year I've been having lower back pain. I cant bend down properly and I cant sit or lay down in a comfortable position. I'm 5'6 and have a very broad complexion, my weight is average, maybe a pound or two above the average weigh

I've been taking Gabapentin 300 mg twice a day for the past week. It was prescribed to deal with itchy skin syndrome caused by Polycythemia vera. The itching has entirley subsided, but I have been experiencing significant back and shoulder pain, usua

I took Beano (only one pill) last week and 2 hours later I ended up with a terrible stomach pain.I did not connect the dots, I suspected that it was caused by certain ingredients in the food I was eating. Itwas a very unique pain

Yesterday, after taking Sam-e with Glucosamine. I got a pain between my shoulder blade, jaw pain, dizziness, sweating. felt like a heart attack. I did not go to the hospital because of the money needed. No ins

<b><span style='font-weight: normal;'><b>After 6 weeks of oral lamisil I experienced</b>eczema, muscle weakness, asthma, bloody bowels, lower abdominal pain, dizziness, extreme f

63 yo man received Zostavax injection in the left upper arm 12/13/11. Developed painful blister on the right shoulder and pain at the right lower ribs 12/10/11.

After using Clobetasol for a two week cycle, my doctor suggested I use it one day during the week, applying it twice that day. Since that time, I have experinced severe chest pain. I recently saw my doctor for heart attack symptoms before I reali

Arthritis Treatment Safe, Natural Cure for Adults. Synflex Liquid Glucosamine, Rheumatoid Arthritis Joint Pain Relief Remedy, Diet Supplements. Synflex, Glucosamine for Dogs. Free Shipping! &lt;a href='http://www.healthyjointcare.com/'&g

Marax was the asthma the best medicine for me to treat asthma. Inhalers do not work. Apparently centuries of using the contents of Marax with success does not count with the FDA. Shame on them. Bring back this medication.

My father is 68 and retired, he is also diabetic. He suffers from severe joints, hip and back pain. He has been using panadol extra strength but finds it takes too long to act. He is also allergic to aspirin and was hospitalized with a ruptured u

My son was suffering from Head ache for the past one year. I have taken him to an ENT & he prescribed Sibelium 10 mg. & he was taking sibelium 3 months back for migraine and he was experiencing fatigue and drowsiness every day. Every t

While taking Pradaxa I had severe knife feeling pain in left eye. I have been off 2 days and it is better. I will check with eye docotr this week and see if it is eye or meds.

BACK PAIN Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Safety Study of 3 mg/mL Baclofen Injection (Intrathecal) Using A Programmable Pump
Condition: Severe Spasticity
Intervention: Drug: Gablofen® 3 mg/mL (Baclofen injection)
Outcome Measures: The rate of inflammatory granulomas in patients given 3 mg/mL Gablofen® (Baclofen injection) 3mg/mL by the intrathecal route of administration.;   Overall safety of 3 mg/mL Gablofen® (Baclofen injection) given by the intrathecal route of administration
2 Recruiting Preventing Alcohol Withdrawal With Oral Baclofen
Conditions: Alcoholism;   Alcohol Withdrawal
Intervention: Drug: Baclofen
Outcome Measures: Alcohol withdrawal severity as measured on CIWA-AR (Clinical Institute for Withdrawal Assessment) scale;   Total benzodiazepine dose required
3 Not yet recruiting Oral and IV Baclofen in Adult Volunteers
Condition: Baclofen Withdrawal Syndrome
Interventions: Drug: Oral Baclofen;   Drug: Intervenous Baclofen
Outcome Measures: oral bioavailability;   Area Under the Curve From Time Zero to Extrapolated Infinite Time [AUC (0 - ∞)];   Plasma Decay Half-Life (t1/2);   Maximum concentration (Cmax);   Tmax;   assessment of sedation;   Ataxia;   Nystagmus;   blood pressure
4 Not yet recruiting Dose Escalation Study of Intravenous Baclofen in Healthy Adult Volunteers
Condition: Safety and Pharmacokinetics of Intravenous Baclofen
Intervention: Drug: Intravenous Baclofen
Outcome Measures: Safety assessments;   Maximum Concentration(Cmax);   AUC(0-inf);   Plasma Decay Half-life (T1/2)
5 Not yet recruiting Action of Baclofen Capsules in Spasticity Due to Multiple Sclerosis
Condition: Spasticity
Interventions: Drug: Baclofen dose 1;   Drug: Baclofen dose 2;   Drug: Placebo
Outcome Measures: Primary efficacy outcome: Improvement in Ashworth score;   Spasm frequency;   Nighttime awakening score;   Clinical global impression of change;   Subject's global impression of change
6 Recruiting Baclofen Effects in Cigarette Smokers
Condition: Nicotine Dependence
Interventions: Drug: Baclofen;   Drug: placebo
Outcome Measures: fMRI response in the ventral striatum/medial orbitofrontal cortex during smoking cue exposure;   Urine cotinine;   Cigarettes smoked per day
7 Recruiting Efficacy and Safety of Baclofen ER Capsules (GRS) in Subjects With Spasticity Due to Multiple Sclerosis
Condition: Spasticity
Interventions: Drug: Baclofen ER Capsules;   Drug: Placebo GRS
Outcome Measures: The primary efficacy outcome is the proportion of subjects who become a treatment failure during double-blind randomized withdrawal;   Determining the safety profile when administered over >12 weeks;   Subject Global Impression of Severity (SGIS)assessment
8 Recruiting Efficacy and Safety of High Dose Baclofen for Alcohol Dependence
Condition: Alcoholism
Interventions: Drug: Baclofen;   Drug: Placebo
Outcome Measures: Mean % Heavy Drinking Days;   Mean % Abstinent Drinking Days;   Anxiety level based on Spielberger Scale for State Anxiety
9 Recruiting Baclofen Effects on Marijuana Dependence
Condition: Marijuana Dependence
Interventions: Drug: Baclofen;   Behavioral: Psychosocial;   Drug: Placebo
Outcome Measure: Change in brain and behavioral responses during reward and inhibitory tasks at fMRI 1, fMRI 2, and fMRI 3; A composite measure
10 Recruiting A Clinical Evaluation Of The Safety Of Baclofen Er Capsules (Grs) When Administered Once Daily To Subjects With Spasticity Due To Multiple Sclerosis (Ms): An Open Label, Long Term, Safety Trial
Condition: Spasticity
Intervention: Drug: Baclofen
Outcome Measures: No. of participants with adverse events;   No. of participants with adverse vital signs;   Number of participants with adverse laboratory parameters
11 Not yet recruiting Preventing Alcohol Withdrawal Syndrome With Oral Baclofen
Condition: Alcohol Withdrawal Syndrome
Interventions: Drug: Baclofen;   Drug: Placebo
Outcome Measures: Prevention of Progression to Severe Alcohol withdrawal;   Reduced Severity of alcohol withdrawal (measured be SEWS score);   Reduced benzodiazepine administration in treatment group
12 Unknown  Baclofen as Add-On to Standard Treatment of Alcohol- Dependent Patients
Condition: Alcohol Dependence
Intervention: Drug: Baclofen (as add-on to standard treatment of alcohol dependence)
Outcome Measures: clinical efficacy and safe side-effect profile of Baclofen in patients suffering from alcohol dependence;   an improvement of the quality of life and associated psychosocial variables such as self-perceptions
13 Not yet recruiting A Study of Baclofen ER
Condition: Cocaine Dependence
Interventions: Drug: Baclofen ER;   Drug: Placebo
Outcome Measure: Urines positive for benzoylecgonine (BE), (a metabolite of cocaine)
14 Unknown  Placebo Controlled Study of Baclofen for GERD in Children With Cerebral Palsy
Conditions: Cerebral Palsy;   GERD
Interventions: Drug: Baclofen;   Drug: placebo
Outcome Measures: Symptom control;   GERD control;   side effects of Baclofen
15 Recruiting A Study to Examine the, Safety, Tolerability and Pharmacokinetics Co-Administered Baclofen and Memantine in Obese and Lean, Otherwise Healthy Adults
Conditions: Healthy Volunteers;;   Obese, Otherwise Healthy Volunteers
Interventions: Drug: Baclofen;   Drug: Memantine;   Drug: Placebo
Outcome Measures: Safety and tolerability of co-administered Baclofen and memantine via C-SSRS;   Safety and tolerability of co-administered Baclofen and memantine via Adverse Events;   Safety and tolerability of co-administered Baclofen and memantine via Vital Signs;   Safety and tolerability of co-administered Baclofen and memantine via ECG;   Safety and tolerability of co-administered Baclofen and memantine via Clinical Laboratory Tests;   Pharmacokinetic parameters of co-administered Baclofen and memantine via Cmax;   Pharmacokinetic parameters of co-administered Baclofen and memantine via Tmax;   Pharmacokinetic parameters of co-administered Baclofen and memantine via AUC;   Pharmacokinetic parameters of co-administered Baclofen and memantine via MRT;   Pharmacokinetic parameters of co-administered Baclofen and memantine via CL/F;   Pharmacokinetic parameters of co-administered Baclofen and memantine via T1/2;   Pharmacokinetic parameters of co-administered Baclofen and memantine via CLR
16 Recruiting Baclofen in the Treatment of Alcoholic Liver Disease
Condition: Alcoholic Liver Disease
Interventions: Drug: Baclofen 30mg/day;   Drug: Baclofen 75mg/day;   Drug: Placebo
Outcome Measures: alcohol consumption;   clinical markers of liver injury;   incidence of hepatic side effects;   craving for alcohol;   early termination due to side effects
17 Recruiting Baclofen for Treating Anxiety and Alcoholism
Conditions: Alcoholism;   Alcohol Dependence;   Alcohol Drinking Related Problems;   Alcohol Drinking;   Anxiety Disorder
Intervention: Drug: Baclofen
Outcome Measures: Alcohol drinking during the Alcohol Self-Administration, expressed as Standard Drinking Units (SDUs) will be measured as the primary outcome during the CR/ASA session.;   Secondary objectives include Baclofen s effects on alcohol cue-induced responses (urge to drink, attention to cues, blood pressure, heart rate, saliva), on the subjective effects of alcohol and on anxiety levels.
18 Unknown  Open Label Treatment of Severe Tactile Defensiveness With Intrathecal Baclofen
Conditions: Tactile Defensiveness;   Autism Spectrum Disorder
Intervention: Drug: Baclofen, intrathecal
Outcome Measures: Modified Short Sensory Profile.;   Clinical Global Impression of Change in Autism Symptoms
19 Unknown  Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes?
Condition: Cerebral Palsy
Interventions: Drug: oral Baclofen + placebo;   Drug: placebo + oral Baclofen
Outcome Measure: care and comport questionnaires
20 Recruiting GABA-B Receptor Function in Healthy Volunteers
Conditions: No Condition;   Brain GABA-B Function
Interventions: Drug: Baclofen 10mg;   Drug: Baclofen 60mg;   Drug: placebo
Outcome Measure: EEG spectral power in theta band