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BACK PAIN and Methadone

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BACK PAIN Symptoms and Causes

If you've ever groaned, "Oh, my aching back!", you are not alone. Back pain is one of the most common medical problems, affecting 8 out of 10 people at some point during their lives. Back pain can range from a dull, constant ache to a sudden, sharp pain. Acute back pain comes on suddenly and usually lasts from a few days to a few weeks. Back pain is called chronic if it lasts for more than three months.

Most back pain goes away on its own, though it may take awhile. Taking over-the-counter pain relievers and resting can help. However, staying in bed for more than 1 or 2 days can make it worse.

If your back pain is severe or doesn't improve after three days, you should call your health care provider. You should also get medical attention if you have back pain following an injury.

Treatment for back pain depends on what kind of pain you have, and what is causing it. It may include hot or cold packs, exercise, medicines, injections, complementary treatments, and sometimes surgery.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Check out the latest treatments for BACK PAIN

BACK PAIN treatment research studies

Methadone clinical trials, surveys and public health registries


Find Drug Side Effect reports



Methadone Side Effects

Toxicity To Various Agents (601)
Cardiac Arrest (334)
Respiratory Arrest (316)
Completed Suicide (256)
Overdose (197)
Death (147)
Electrocardiogram Qt Prolonged (142)
Torsade De Pointes (97)
Respiratory Depression (82)
Cardio-respiratory Arrest (73)
Somnolence (65)
Accidental Overdose (59)
Nausea (57)
Pulmonary Oedema (57)
Loss Of Consciousness (54)
Vomiting (51)
Confusional State (47)
Pneumonia (40)
Dyspnoea (39)
Syncope (39)
Mental Status Changes (38)
Pain (37)
Fall (37)
Sedation (36)
Bronchopneumonia (36)
Dizziness (35)
Hypotension (31)
Convulsion (31)
Hyperhidrosis (31)
Malaise (30)
Depressed Level Of Consciousness (30)
Coma (29)
Unresponsive To Stimuli (27)
Intentional Overdose (27)
Constipation (27)
Feeling Abnormal (26)
Hypokalaemia (26)
Pulmonary Congestion (26)
Renal Failure Acute (26)
Ventricular Tachycardia (25)
Headache (25)
Fatigue (25)
Brain Oedema (25)
Lethargy (24)
Rhabdomyolysis (24)
Respiratory Failure (24)
Incorrect Dose Administered (23)
Bradycardia (23)
Accidental Poisoning (23)
Miosis (22)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

Back pain in my mid backafter 3-5 hrs of sleep, constant tossing and turning for rest of night.

For 7 months, I've been weak in my right leg with numbness in my right foot and hip. It's been so difficult moving around, so I don't go outside unless I have a medical appointment. Around May ending, after 8 months of pain and great anxiety, I recei

Good afternoon doc,my name dimasautisme,i comefrom indonesia ? im methadoners with 120 mg,im drink ARV to?please private my status? i just want quesstion i want to detox,where i must go to hospital doc? please help me :-D :)

HELLO IAM STACEY HENDERSON,SORRY I PUT CAP'S JUST INCASE YOU COULDN'T READ IT I JUST WANTED TO ASK A QUESTION FOR MY DAD AS IAM VERY WORRIED HE'S BEEN SUFFERING WITH BACK PAIN ALL HIS LIFE AND I WOULD LIKE TO KNOW WHAT ARE THE SIDE EFFECTS FOR THE PA

I have been on methadone for two years. Went fro 70 mgs a day to 20. I do for pain and I have been prescribed klonipin also recently for severe panic attacks and I read online that it's a deadly combo. I take my methadone at 9 am. And have panic

I'm 13 and since last year I've been having lower back pain. I cant bend down properly and I cant sit or lay down in a comfortable position. I'm 5'6 and have a very broad complexion, my weight is average, maybe a pound or two above the average weigh

I've been taking Gabapentin 300 mg twice a day for the past week. It was prescribed to deal with itchy skin syndrome caused by Polycythemia vera. The itching has entirley subsided, but I have been experiencing significant back and shoulder pain, usua

Ive been takeing 90mls of methadone for approxamitley 2 years on and off but properly this time for a total off 7 months i get servere sweating from taking my methadone and feel very hot like im burning up and dripping with sweat why is this happenin

Methodone Side Effects, I have had many trips to Emergency Unit at my Town, having tight painful heart problems. But when they do the Tests for Heart attacks, I jave always been told I have no problem my heart is fine. I have had ECG Tests, all fine.

What causes vitimin d deficirncy. i take calicum with 600mg of d take calatrol .5mg. my levels are still low. why?

I took Beano (only one pill) last week and 2 hours later I ended up with a terrible stomach pain.I did not connect the dots, I suspected that it was caused by certain ingredients in the food I was eating. Itwas a very unique pain

Yesterday, after taking Sam-e with Glucosamine. I got a pain between my shoulder blade, jaw pain, dizziness, sweating. felt like a heart attack. I did not go to the hospital because of the money needed. No ins

<b><span style='font-weight: normal;'><b>After 6 weeks of oral lamisil I experienced</b>eczema, muscle weakness, asthma, bloody bowels, lower abdominal pain, dizziness, extreme f

63 yo man received Zostavax injection in the left upper arm 12/13/11. Developed painful blister on the right shoulder and pain at the right lower ribs 12/10/11.

After using Clobetasol for a two week cycle, my doctor suggested I use it one day during the week, applying it twice that day. Since that time, I have experinced severe chest pain. I recently saw my doctor for heart attack symptoms before I reali

Arthritis Treatment Safe, Natural Cure for Adults. Synflex Liquid Glucosamine, Rheumatoid Arthritis Joint Pain Relief Remedy, Diet Supplements. Synflex, Glucosamine for Dogs. Free Shipping! &lt;a href='http://www.healthyjointcare.com/'&g

Marax was the asthma the best medicine for me to treat asthma. Inhalers do not work. Apparently centuries of using the contents of Marax with success does not count with the FDA. Shame on them. Bring back this medication.

My father is 68 and retired, he is also diabetic. He suffers from severe joints, hip and back pain. He has been using panadol extra strength but finds it takes too long to act. He is also allergic to aspirin and was hospitalized with a ruptured u

My son was suffering from Head ache for the past one year. I have taken him to an ENT & he prescribed Sibelium 10 mg. & he was taking sibelium 3 months back for migraine and he was experiencing fatigue and drowsiness every day. Every t

While taking Pradaxa I had severe knife feeling pain in left eye. I have been off 2 days and it is better. I will check with eye docotr this week and see if it is eye or meds.

BACK PAIN Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting The Use of Methadone in Newborn Infants
Conditions: Premature Birth of Newborn;   Critically Ill
Intervention: Drug: Methadone
Outcome Measures: Methadone PK and EDDP;   DNA
2 Recruiting Methadone in Pediatric Anesthesiology II
Condition: Pain
Interventions: Drug: Group 1- 0.4mg/kg IV Methadone HCl;   Drug: Group 2 - 0.5mg/kg IV methadon HCI;   Other: Group 3 - control no Methadone
Outcome Measures: Morphine consumption;   Pain scores;   Methadone clearance
3 Recruiting CYP2B6 Polymorphisms in Methadone
Condition: Healthy Volunteers
Interventions: Drug: racemic Methadone HC1;   Drug: Oral deuterated racemic Methadone HCl,
Outcome Measures: The effects of Methadone on healthy volunteers;   Methadone and bupropion concentration;   Methadone and bupropion clearance from the body;   Oral Methadone and bupropion absorption;   Influence of CYP2B6*6 hetero or homozyge genotype on the above primary and secondary outcomes
4 Unknown  Compare Methadone Combined With N-Acetyl-Cysteine (NAC) and Methadone Alone for Opioids Astaining
Condition: Opioids Use
Interventions: Drug: Methadone; NAC;   Drug: Methadone
Outcome Measure:
5 Recruiting Treatment of Pain in Head-and-Neck Cancer Patients: is Methadone More Effective?
Conditions: Pain;   Cancer of Head and Neck
Interventions: Drug: fentanyl;   Drug: Methadone
Outcome Measures: significant pain relief (reduction of Numeric Rating Scale (NRS) of 50%);   time to achieve significant pain relief;   side-effect profile
6 Recruiting Methadone vs Magnesium in Spinal Fusion
Condition: Idiopathic Scoliosis
Interventions: Drug: Methadone hydrochloride;   Drug: Magnesium Sulfate;   Drug: Remifentanil
Outcome Measures: Intra- and Post-operative Pain Relief;   Intra-operative parameters
7 Not yet recruiting Drug Interaction & Methadone & Buprenorphine
Condition: Hepatitis C
Interventions: Drug: Methadone;   Drug: DCV 3DAA FDC;   Drug: BMS-791325;   Drug: Buprenorphine;   Drug: Naloxone
Outcome Measures: Maximum observed concentration (Cmax) of R-Methadone for Part 1;   Area under the concentration-time curve in one dosing interval (AUC(TAU)) of R-Methadone for Part 1;   Cmax of Buprenorphine and Norbuprenorphine for Part 2;   AUC(TAU) of Buprenorphine and Norbuprenorphine for Part 2;   Cmax of S-Methadone and Total Methadone for Part 1;   AUC(TAU) of S-Methadone and Total Methadone for Part 1;   Concentration at 24 hours (C24) of S-Methadone, Total Methadone and R-Methadone for Part 1;   Time of maximum observed concentration (Tmax) of S-Methadone, Total Methadone and R-Methadone for Part 1;   C24 of Buprenorphine and Norbuprenorphine for Part 2;   Tmax of Buprenorphine and Norbuprenorphine for Part 2;   Ratio of metabolite AUC(TAU) to parent AUC(TAU) (MR_AUC(TAU)) of Norbuprenorphine to Buprenorphine;   Cmax of of Daclatasvir (DCV) , Asunaprevir (ASV) , BMS-791325, and BMS-794712;   AUC(TAU) of DCV, ASV, BMS-791325, and BMS-794712;   Concentration at 12 hours (C12) of DCV, ASV, BMS-791325, and BMS-794712;   Tmax of DCV, ASV, BMS-791325, and BMS-794712;   MR_AUC(TAU) for BMS-794712 to BMS-791325;   Incidence of Adverse Events (AEs), Serious Adverse Events (SAEs), death and AEs leading to discontinuation;   Results of vital signs, Electrocardiograms (ECGs), Physical Examinations (PEs) and clinical labs;   Scores of Clinical Opiate Withdrawal Scale (COWS), Subjective Opiate Withdrawal Scale (SOWS), Objective Opiate Withdrawal Scale (OOWS), and Opiate Overdose Assessment (OOA)
8 Recruiting Pharmacokinetics of Multiple Dose Methadone in Children Treated for Opiate Withdrawal
Condition: Opiate Withdrawal Syndrome
Intervention: Drug: Methadone
Outcome Measures: PK Parameters after multiple doses of enteral Methadone;   PK of Methadone's primary metabolite EDDP;   PK of R- and S-enantiomers of Methadone;   Correlation between plasma and DBS samples;   Correlation between plasma and scavenge samples;   Influence of CYP3A4 and CYP3B6 genetic polymorphisms on Methadone PK;   Methadone pharmacodynamics using the WAT-1;   Adverse events
9 Unknown  Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone
Conditions: Post Operative Pain;   Hyperalgesia
Interventions: Drug: ketamine infusion;   Drug: Methadone PCA
Outcome Measures: the extent of hyperalgesia area proximal to surgical wound;   pain intensity;   opioids related adverse events
10 Unknown  Methadone Versus Morphine for Orthopedic Surgery Patients
Conditions: Fracture;   Pain, Postoperative
Interventions: Drug: Methadone;   Drug: Morphine
Outcome Measures: Opioid consumption during the 48 hours after surgery;   Time to initial dose of rescue analgesic;   Overall rescue analgesic;   Side effects with special attention paid to respiratory rate and possible respiratory depression, and PONV;   Overall satisfaction of the patient with the analgesic graded on a scale of 1-5
11 Recruiting Evaluation of the Efficacy and Safety of Two Methadone Titration Methods for the Treatment of Cancer-related Pain With Inadequate Pain Relief or Intolerable Side Effects When Treated With Level 3 Opioids.
Condition: Pain Related to Cancer
Intervention: Drug: Methadone
Outcome Measure: Binary main criterion based on success/failure rate related to Methadone switch on Day 4.
12 Unknown  Efficacy of Drug and Risk Counseling Among Methadone Patients in Jakarta, Indonesia
Conditions: HIV Risk Behaviors;   Heroin Injection;   Retention in Methadone Treatment
Interventions: Behavioral: Behavioral Drug and Risk Counseling (BDRC);   Behavioral: Methadone maintenance treatment
Outcome Measures: Injection drug use;   retention in Methadone treatment
13 Unknown  Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone
Condition: Substance-Related Disorders
Interventions: Drug: midazolam(drug), digoxin (drug);   Drug: Bupropion (drug);   Drug: Methadone (drug)
Outcome Measures: Explore if there is a correlation between the areas of the concentration curves of probe substrates for CYP3A4 and/or CYP2B6 and Pgp and the area of the concentration curve of Methadone.;   LC-MS assays will be developed to analyze the plasma content of the probe substrates, Methadone and their metabolites. Specifically, midazolam, 1-OH midazolam, bupropion, t-butyl-hydroxy bupropion, digoxin, Methadone, and EDDP (a Methadone metabolite).;   Isolate and bank the DNA of the subjects for future genotyping of variant alleles that will be identified in this study to be important in Methadone pharmacokinetics.
14 Recruiting Efficacy Methadone for Management Postoperative Pain After the Use of Anesthesia Intravenous in Laparoscopic Cholecystectomy
Condition: Pain, Postoperative
Interventions: Drug: Morphine;   Drug: Methadone;   Drug: TIVA
Outcome Measures: Difference in milligrams of morphine used as rescue analgesia;   Difference in pain scores, using the Numeric Rating Scale
15 Not yet recruiting Pilot Study of Nicotine Nasal Spray and Varenicline on Smoking in Methadone-Maintained Patients
Conditions: Cigarette Smoking;   Methadone Maintenance
Interventions: Drug: Nicotine Nasal Spray;   Drug: Varenicline;   Drug: Placebo Nasal Spray;   Drug: Placebo Varenicline
Outcome Measures: Proportion of daily cigarettes smoked in the 4 hours after receiving Methadone dose;   Cigarettes per day;   Carbon monoxide level
16 Recruiting Pupillometry and Pain Thresholds Patients Substituted by Methadone and Buprenorphine
Conditions: Opiate Dependent;   Previous Illicit Drug Use
Intervention: Drug: Buprenorphine and Methadone Hydrochloride
Outcome Measures: Measurement of the pupil diameter;   - The mechanical punctuate pain threshold as measured by Electronical Von Frey;   - The mechanical pressure pain threshold measured by Algometer on the tibial bone;   - The pupil diameter measured in scotopic .conditions (via infrared camera) at the hypothetical peak effect of either Methadone or buprenorphine.;   - The pupil diameter measured in photopic conditions (via infrared camera) at the hypothetical residual effect of either Methadone or buprenorphine
17 Recruiting Buprenorphine and Methadone for Opioid-dependent Chronic Back Pain Patients
Condition: Low Back Pain
Interventions: Drug: Methadone;   Drug: Buprenorphine/naloxone
Outcome Measures: Analgesia;   Illicit drug use;   Cravings;   Functioning;   Depression;   Treatment retention
18 Recruiting Conversion From Parenteral to Oral Methadone.
Condition: Pain
Interventions: Drug: Parenteral /oral Methadone ratio 1:2;   Drug: Parenteral /oral Methadone ratio 1:1.2
Outcome Measures: Proportion of intoxicated patients in each groups;   Parenteral/oral MTD final ratio in patients considered as "failure"
19 Recruiting Methadone in Pediatric and Adult Sickle Cell Patients
Condition: Sickle Cell Disease
Interventions: Drug: Morphine;   Drug: Methadone
Outcome Measures: To determine the pharmacokinetics of Methadone in children and adults with Sickle Cell disease experiencing a VOE.;   Pain
20 Unknown  Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain
Conditions: Cancer;   Pain;   Palliative Care
Intervention: Drug: Methadone plus Acetaminophen or Placebo
Outcome Measures: Pain intensity and time to equianalgesic effect;   Degree of nausea, vomiting, obstipation, xerostomia and drowsiness