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CHEST DISCOMFORT and Thyroid

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CHEST DISCOMFORT Symptoms and Causes

Each year almost 800,000 Americans have a heart attack. A heart attack happens when blood flow to the heart suddenly becomes blocked. Without the blood coming in, the heart can't get oxygen. If not treated quickly, the heart muscle begins to die. But if you do get quick treatment, you may be able prevent or limit damage to the heart muscle. That's why it's important to know the symptoms of a heart attack and call 9-1-1 if you or someone else is having them. You should call, even if you are not sure that it is a heart attack.

The most common symptoms in men and women are

  • Chest discomfort. It is often in center or left side of the chest. It usually lasts more than a few minutes. It may go away and come back. It can feel like pressure, squeezing, fullness, or pain. It also can feel like heartburn or indigestion.
  • Shortness of breath. Sometimes this is your only symptom. You may get it before or during the chest discomfort. It can happen when you are resting or doing a little bit of physical activity.
  • Discomfort in the upper body. You may feel pain or discomfort in one or both arms, the back, shoulders, neck, jaw, or upper part of the stomach.

You may also have other symptoms, such as nausea, vomiting, dizziness, and lightheadedness. You may break out in a cold sweat. Sometimes women will have different symptoms then men. For example, they are more likely to feel tired for no reason.

The most common cause of heart attacks is coronary artery disease (CAD). With CAD, there is a buildup of cholesterol and other material, called plaque, on their inner walls or the arteries. This is atherosclerosis. It can build up for years. Eventually an area of plaque can rupture (break open). A blood clot can form around the plaque and block the artery.

A less common cause of heart attack is a severe spasm (tightening) of a coronary artery. The spasm cuts off blood flow through the artery.

At the hospital, health care providers make a diagnosis based on your symptoms, blood tests, and different heart health tests. Treatments may include medicines and medical procedures such as coronary angioplasty. After a heart attack, cardiac rehabilitation and lifestyle changes can help you recover.

NIH: National Heart, Lung, and Blood Institute

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CHEST DISCOMFORT treatment research studies

Thyroid clinical trials, surveys and public health registries


Find Drug Side Effect reports



Thyroid Side Effects

Fatigue (48)
Hypothyroidism (38)
Alopecia (37)
Product Formulation Issue (23)
Headache (23)
Palpitations (22)
Diarrhoea (21)
Feeling Abnormal (21)
Dizziness (21)
Dyspnoea (21)
Product Substitution Issue (20)
Pain (20)
Chest Pain (20)
Asthenia (19)
Weight Increased (19)
Product Quality Issue (18)
Blood Thyroid Stimulating Hormone Increased (17)
Blood Pressure Increased (17)
Heart Rate Increased (17)
Depression (17)
Insomnia (17)
Myalgia (16)
Nausea (15)
Hypertension (15)
Arthralgia (15)
Atrial Fibrillation (15)
Dry Skin (14)
Rash (13)
Tremor (12)
Urticaria (12)
Pain In Extremity (12)
Malaise (12)
Abdominal Pain Upper (11)
Anxiety (11)
Condition Aggravated (11)
Hyperhidrosis (11)
Thyroid Function Test Abnormal (10)
Muscle Spasms (9)
Deep Vein Thrombosis (9)
Flatulence (9)
Hyperthyroidism (9)
Heart Rate Irregular (9)
Confusional State (8)
Blood Thyroid Stimulating Hormone Decreased (8)
Constipation (8)
Vomiting (8)
Weight Decreased (8)
Oedema Peripheral (8)
Extrasystoles (8)
Suicidal Ideation (7)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
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Celebrex (12876 )
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Cipro (8580)
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Flexeril (435)
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Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
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Prednisone (5926)
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Prozac (1954)
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Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
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Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

I have been getting these little blister sores that bust and turn into scap little sores. I have noticed it since about a month or so after found out my thyroid is not working right. Could this be a side effect from the medication

I have only been on it five days, it is better than nothing so far. My own thyroid production took a downfall and I am used to Armour Thyroid which has been my doctor's first choice for years. I was told by my European Doctor that Synthyroid is jus

I'm losing a lot of weight. Was 110 when started on Armour. Lost 15 lbs in one year. Take 90

In the Spring of 2008 I went to my PCP for allergy symptoms, and when he felt my neck glands to make sure that I didn't have something similiar to strept throat, he said that's the biggest Thyrioid I've ever felt, well 2 weeks later the surgeon was r

My husbadn is almost 52, and he has been very ill with a chronic GI condition for the last 12 months. He has been in and out of the hospital and had his gull bladder and appendix removed. They still have no diagnosis for the GI problems. Now last wee

Recently I was put on medication for thyroid. Its a powder compound and they put into capsules for me to take. Its 60mg 1 daily then after one week 1 twice a day. I took it Saturday no side effects. Then Sunday I had no energy and I was so cold I cou

After using Clobetasol for a two week cycle, my doctor suggested I use it one day during the week, applying it twice that day. Since that time, I have experinced severe chest pain. I recently saw my doctor for heart attack symptoms before I reali

After the second day taking Lekoklar XL chest pains started and have not let up (I am on 4th day of medication). My cough has gotten better but temperature is still up and am feeling weaker now than ever.

I am real tired I've been on coreg about two weeks, I don't know if Ican keep taking it. I am so sleepy all the time don't want to do anything my chest hurts. Don't know what to do, if Idon't take it my heart want work right. JUST STUCK

When I eat or drink this burning feeling in my chest going up like I am about vomiting.what is happening? And something I and chest pain too! And I am 14 and a girl

Emotional Anxciety then chest pain, jaw pain on left side and headaches, I am not taking it no more. there has to be something else less tramatising to my system. It was bad enugh that i was at work when the emotional anxiety hit. not cool at all.

Intersting on the Bicor . i have been on it since march this year , starting with 2.5 , then to 5.0 , 7.5 and 10mg for the last 3 months . always felt tired in the increse dosage as advised . but now have had a fe w joint aches , chest pains and cur

Recently in the ultrasound by the radio logist the report says I have mild pyelocaliectasia . I am ok except freqiency in urine at night or when i take rice. There as such no visible sign or discomfort.

>:o Took my first dose today,it left me covered in a red itchy rash on neck,chest,back and sides within 10 minutes of consuming.This product is now sitting in the trash can. :(

When lying down, become chest congested and must get rid of mucous. No or little problem during day. Is this common? does any one else have this. Should I be scared?

one 10 mg pill cuased presure in thechest bad muslespasms in the back think past doses has sent me skizzo

CHEST DISCOMFORT Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Thyroid Hormone Dose Adjustment in Pregnancy
Conditions: Pregnancy;   Hypothyroidism
Interventions: Drug: Anticipatory dose increase of levothyroxine;   Drug: levothyroxine
Outcome Measures: proportion of patients in each treatment arm euthyroid through gestation;   the proportion of patients in each arm who required, and the gestation week at which, levothyroxine dose adjustments (either increased or decreased) occurred to maintain a euthyroid state;   Determination of the necessary frequency of serum evaluation of TSH during the first half of gestation.
2 Recruiting Study of Optimal Replacement of Thyroxine in the Elderly
Condition: Hypothyroidism
Intervention: Drug: Levothyroxine
Outcome Measures: Participant's acceptability of study design and willingness to enter study;   Participant recruitment rate;   Time to achieve desired TSH levels;   Medication compliance;   The acceptability of three patient completed questionnaires;   Assessment of mobility;   Change in specific cardiovascular risk factors;   Measure of risk of falls
3 Recruiting Study of Dose Adjustment From Levothyroxine to a New Levothyroxine Sodium Test Formulation.
Condition: Hypothyroidism
Intervention: Drug: Levothyroxine sodium new formulation
Outcome Measures: The proportion of patients that do not need a change of dose.;   The magnitude of the change in daily dose needed.;   Proportion of patients that obtained a thyroid stimulating hormone between 0.4-2.5 mU/L;   Change from baseline serum thyroid stimulating hormone (in mIU/L and percentage).
4 Unknown  Thyroxin Treatment in Sub Clinical Hypothyroidism, on the Apnea Hypopnea Index Score, Lipids and Highly Sensitive CRP
Condition: Dyslipidemia
Interventions: Drug: levothyroxine;   Drug: sugar pill
Outcome Measures: Effect of the treatment of subclinical hypothyroidism on the apnea hypopnea index (AHI) score.;   Effect of the treatment of subclinical hypothyroidism on the lipid profile in patient with dyslipidemia and on hs-CRP
5 Recruiting Effects of L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Hypothyroidism
Conditions: Hypothyroidism;   Thyroid Diseases;   Endocrine System Diseases
Intervention: Drug: L-thyroxine
Outcome Measures: Rate of First CVD Events, CVD Mortality and All-cause Mortality;   Change in Serum Lipid Levels;   Change in Thickness of Blood Vessel Wall;   Change in Oxidative Stress and Chronic Inflammatory Factors Associated with Atherosclerosis
6 Recruiting Desiccated Thyroid Extract and Levothyroxine for Hypothyroidism Treatment
Condition: Primary Hypothyroidism.
Interventions: Drug: Levothyroxine;   Drug: Desiccated thyroid extract
Outcome Measures: thyroid-symptom questionnaire;   Wechsler Memory Scale-Version IV (WMS-IV);   Biochemical measures
7 Recruiting Thyroid Hormone Replacement for Subclinical Hypothyroidism
Condition: Subclinical Hypothyroidism
Interventions: Drug: Levothyroxine;   Drug: Placebo
Outcome Measures: Fatal and non-fatal cardiovascular events;   Thyroid-specific quality of life;   Health-related quality of life;   Handgrip strength;   Executive cognitive function;   Total mortality;   Basic Activities of Daily Living;   Extended activities of daily living;   Haemoglobin
8 Recruiting Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
Conditions: Down Syndrome;   Subclinical Hypothyroidism
Intervention: Drug: Levothyroxine
Outcome Measures: Change in non-HDL cholesterol from baseline at 6, 12 and 18 months.;   Change in quality of life from baseline at 6, 12 and 18 months.
9 Recruiting L-Thyroxine Supplementation for Preterm Newborns Less Than 32 Weeks of Gestation With Hypothyroxinemia
Condition: Hypothyroxinemia
Interventions: Drug: L-Thyroxine;   Drug: water
Outcome Measures: Neurodevelopmental outcome;   Morbidity associated with management of newborns < 32 WG with hypothyroxinemia
10 Recruiting Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism
Conditions: Hypothyroidism;   Thyroid Diseases;   Endocrine System Diseases
Intervention: Drug: L-thyroxine
Outcome Measures: change in lipid profile;   change in thickness of blood vessel wall;   change in endothelial function;   change of adipocytokines;   Change of Oxidative Stress and Chronic Inflammatory Factors Related with Atherosclerosis
11 Recruiting Thyroid Study Type 2 Diabetes Mellitus (T2DM)
Conditions: Diabetes;   Hypothyroidism
Intervention: Drug: Euthyrox (levothyroxine)
Outcome Measures: Thyroid hormone-induced change in whole body insulin sensitivity (change in insulin-stimulated glucose disposal) and muscle mitochondrial function;   Thyroid hormone-induced change of lipid content in skeletal muscle and liver and brown adipose tissue activity
12 Recruiting Early Levothyroxine Post Radioactive Iodine
Condition: Graves' Disease
Intervention: Drug: Levothyroxine
Outcome Measures: Prevention of overt hypothyroidism;   Quality of Life
13 Recruiting Antithyroid Drug Treatment of Thyrotoxicosis in Young People
Condition: Paediatric Thyrotoxicosis
Interventions: Procedure: Block and Replace;   Procedure: Dose Titration;   Drug: carbimazole;   Drug: propylthiouracil;   Drug: thyroxine
Outcome Measures: Remission rate as defined by patients who are biochemically euthyroid at the end of the 6 year study period.;   Biochemical control as reflected by blood TSH and thyroxine levels;   The frequency of adverse events on the 2 treatment regimens.
14 Recruiting The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma
Conditions: Thyroid Carcinoma;   Hypothyroidism
Interventions: Other: Black Coffee;   Other: Coffee with Milk;   Other: Black Tea;   Other: Water
Outcome Measures: Change in TSH (thyrotropin-stimulating-hormone) with each beverage type;   Change in TSH with various beverages;   Change in total T4 with each beverage type;   Change in free T4 with each beverage type;   Change in total T3 with each beverage type
15 Not yet recruiting Thyroid Hormones Treatment in Asthma Exacerbation
Condition: Asthma
Interventions: Drug: IV thyroxin;   Drug: Placebo
Outcome Measures: time to normalization of PEF (peak expiratory flow);   Length of stay;   Time to oxygenation;   heart rate;   respiratory rate
16 Recruiting Selenium Supplementation in Pregnancy
Conditions: Pregnancy;   Infertility;   Auto-immune Thyroiditis
Interventions: Dietary Supplement: Selenium;   Other: Sugar Pill Placebo;   Other: Selenium + L-Thyroxine (LT4);   Other: Sugar Pill Placebo + L-Thyroxine (LT4)
Outcome Measures: Changes in TPOab and/or Tgab;   Changes in thyroid volume and echogenicity;   Changes in thyroid hormones (TSH, FT4, FT3);   Evaluation of Maternal risks;   Evaluation of Infant risks;   Changes in of quality of life;   Evaluation of Health Services:;   Changes in the selenium-dependent antioxidant enzyme glutathione peroxidase;   Changes in implantation and pregnancy rates
17 Recruiting The TRUST Study - Depression Substudy
Conditions: Subclinical Hypothyroidism;   Depression
Interventions: Drug: Levothyroxine;   Drug: Placebo
Outcome Measure: Change from baseline in 15-items Geriatric Depression Scale
18 Recruiting Preconceptional Thyroid Screening and Childhood Nerocognitive Function
Condition: Hypothyroidism
Intervention: Procedure: levothyroxine
Outcome Measures: Offspring neurocognitive assessment at 0-3 yrs;   Offspring IQ assessment at 0-3 yrs;   Incidence of neonatal hypothyroid and complications
19 Unknown  The Effect of Thyroid Hormone Levels in Pregnant Women on the Intelligence Quotient (IQ) of Their Children
Conditions: Child Development Disorders;   Pregnancy;   Subclinical Hypothyroidism
Intervention:
Outcome Measure:
20 Recruiting Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children
Condition: Down Syndrome
Intervention: Drug: thyroid hormone and folinic acid
Outcome Measures: GMDS ( Griffiths Mental Development Scale);   BL (Brunet Lezine revised scale)