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CHEST DISCOMFORT and ZOCOR

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CHEST DISCOMFORT Symptoms and Causes

Each year over a million people in the U.S. have a heart attack. About half of them die. Many people have permanent heart damage or die because they don't get help immediately. It's important to know the symptoms of a heart attack and call 9-1-1 if someone is having them. Those symptoms include

  • Chest discomfort - pressure, squeezing, or pain
  • Shortness of breath
  • Discomfort in the upper body - arms, shoulder, neck, back
  • Nausea, vomiting, dizziness, lightheadedness, sweating

These symptoms can sometimes be different in women.

What exactly is a heart attack? Most heart attacks happen when a clot in the coronary artery blocks the supply of blood and oxygen to the heart. Often this leads to an irregular heartbeat - called an arrhythmia - that causes a severe decrease in the pumping function of the heart. A blockage that is not treated within a few hours causes the affected heart muscle to die.

NIH: National Heart, Lung, and Blood Institute

Check out the latest treatments for CHEST DISCOMFORT

CHEST DISCOMFORT treatment research studies

ZOCOR clinical trials, surveys and public health registries


Find Drug Side Effect reports



ZOCOR Side Effects

Rhabdomyolysis (1045)
Myalgia (844)
Blood Creatine Phosphokinase Increased (494)
Asthenia (430)
Muscular Weakness (393)
Renal Failure Acute (366)
Pain In Extremity (328)
Arthralgia (302)
Muscle Spasms (284)
Fatigue (263)
Myopathy (253)
Renal Failure (231)
Pain (228)
Dyspnoea (220)
Myocardial Infarction (202)
Myositis (201)
Nausea (196)
Alanine Aminotransferase Increased (184)
Chest Pain (179)
Dizziness (178)
Fall (128)
Aspartate Aminotransferase Increased (127)
Malaise (122)
Cerebrovascular Accident (120)
Diarrhoea (119)
Headache (104)
Back Pain (101)
Liver Function Test Abnormal (101)
Depression (100)
Abdominal Pain (95)
Gait Disturbance (93)
Blood Creatinine Increased (93)
Anxiety (92)
Abasia (91)
Vomiting (87)
Amnesia (86)
Abdominal Pain Upper (79)
Anaemia (78)
Coronary Artery Disease (76)
Insomnia (75)
Cardiac Failure Congestive (74)
Weight Decreased (73)
Dehydration (72)
Pyrexia (71)
Confusional State (70)
Paraesthesia (70)
Hypertension (69)
Pneumonia (69)
Rash (68)
Cardiac Disorder (67)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

How long does it take to get back to normal after taking Zocor. I had a major problem in November 2008 and it is now May 2009 and I am still having problems and testing. It has cost me a fortune and they still say it is not Zocor but I still believe

I am asking, does Levaxin a thyroid med. and Zantac antiacid, is it OK to take those at the same time

I have a frozen diagfram and shrinking lung. It affects my breathing and energy. Could this possibly be caused by Zocor as I was told by someone who also has this condition. I also have lots of muscle pain daily.&nbs

Lip swelling, acute.

Urinary retention Is there a correlation between this and using a statin. Had this problem shortly after starting a simvistatin routine.

Zocor 40 mg, Typical gout experience 2 times a month, treatable with fluids and diet. Some use of colchicine. Within a week of using Zocor experienced gout over an extended period of time. Basically 6 weeks straight. Taking Zocor at night and exp

Zocor 40mg. Since I started taking have had rotator repair, frozen shoulder same shoulder, tarsal tunnel in my ankle. Surgery and now frozen shoulder other shoulder that my doc wants to operate on

After using Clobetasol for a two week cycle, my doctor suggested I use it one day during the week, applying it twice that day. Since that time, I have experinced severe chest pain. I recently saw my doctor for heart attack symptoms before I reali

After the second day taking Lekoklar XL chest pains started and have not let up (I am on 4th day of medication). My cough has gotten better but temperature is still up and am feeling weaker now than ever.

I am real tired I've been on coreg about two weeks, I don't know if Ican keep taking it. I am so sleepy all the time don't want to do anything my chest hurts. Don't know what to do, if Idon't take it my heart want work right. JUST STUCK

When I eat or drink this burning feeling in my chest going up like I am about vomiting.what is happening? And something I and chest pain too! And I am 14 and a girl

Emotional Anxciety then chest pain, jaw pain on left side and headaches, I am not taking it no more. there has to be something else less tramatising to my system. It was bad enugh that i was at work when the emotional anxiety hit. not cool at all.

Intersting on the Bicor . i have been on it since march this year , starting with 2.5 , then to 5.0 , 7.5 and 10mg for the last 3 months . always felt tired in the increse dosage as advised . but now have had a fe w joint aches , chest pains and cur

Recently in the ultrasound by the radio logist the report says I have mild pyelocaliectasia . I am ok except freqiency in urine at night or when i take rice. There as such no visible sign or discomfort.

>:o Took my first dose today,it left me covered in a red itchy rash on neck,chest,back and sides within 10 minutes of consuming.This product is now sitting in the trash can. :(

When lying down, become chest congested and must get rid of mucous. No or little problem during day. Is this common? does any one else have this. Should I be scared?

one 10 mg pill cuased presure in thechest bad muslespasms in the back think past doses has sent me skizzo

CHEST DISCOMFORT Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Study of Metformin With Simvastatin for Men With Prostate Carcinoma
Condition: Prostate Carcinoma
Interventions: Drug: Metformin;   Drug: Simvastatin
Outcome Measures: Efficacy, as measured by an improvement in PSA doubling time (PSADT) between baseline and 6 months, of the combination of metformin plus simvastatin in patients with recurrent prostate cancer following definitive treatment.;   Time to protocol-specified event for men treated with the combination of metformin plus simvastatin.;   Pattern of change in log PSA levels and PSA velocity over time during treatment with metformin plus simvastatin.;   Associations between changes in metabolic parameters (fasting glucose/insulin/lipid panel/leptin/adiponectin and others) with the pattern of change in log PSA levels.
2 Recruiting Safety of Simvastatin in LAM and TSC
Conditions: Lymphangioleiomyomatosis;   Tuberous Sclerosis Complex
Intervention: Drug: Simvastatin
Outcome Measures: Safety of simvastatin in the treatment of LAM-S and LAM-TS patients on a stable (for at least 3 months) dose of sirolimus or everolimus.;   FEV1, FVC, DLCO, VEGF-D, and QOL; signs of clinical benefit.
3 Not yet recruiting Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin
Conditions: Breast Cancer;   Stage I Breast Cancer;   Stage II Breast Cancer;   Stage III Breast Cancer
Interventions: Drug: Simvastatin;   Drug: Doxorubicin/cyclophosphamide
Outcome Measures: Change in echocardiographic Global Longitudinal Strain (GLS);   Number of participants with adverse events as a measure of safety and tolerability;   Recurrence free survival (RFS) with concurrent simvastatin
4 Unknown  Trial of XELIRI/FOLFIRI + Simvastatin Followed by Simvastatin Maintenance in Metastatic Colorectal Cancer
Condition: Colorectal Cancer
Intervention: Drug: Simvastatin
Outcome Measure: Progression free survival
5 Recruiting Simvastatin and Fenofibrate vs Simvastatin Alone in Patients With Type 2 Diabetes Mellitus and Acute Coronary Syndrome
Conditions: Acute Coronary Syndrome;   Diabetes Mellitus, Type 2;   Hypertriglyceridemia
Interventions: Drug: Fenofibrate;   Drug: Simvastatin
Outcome Measures: Percentage change from baseline in triglycerides (TG) at week 12;   Percentage of patients who achieved non-High-Density Lipoprotein-Cholesterol (non-HDL-C) level less than 2,6 mmol/l at week 12;   Percentage changes from baseline in apoB/apoA1 ratio at week 12;   Percentage changes from baseline in non-High-Density Lipoprotein-Cholesterol (non-HDL-C) at week 12;   Percentage changes from baseline in High-Density Lipoprotein-Cholesterol (HDL-C) at week 12;   Percentage changes from baseline in Low-Density Lipoprotein-Cholesterol (LDL-C) at week 12;   Percentage changes from baseline in uric acid at week 12;   Percentage of patients who achieved non-High-Density Lipoprotein-Cholesterol (non-HDL-C) level less than 2,6 mmol/l at week 52;   Percentage changes from baseline in apoB/apoA1 ratio at week 52;   Percentage changes from baseline in non-High-Density Lipoprotein-Cholesterol (non-HDL-C) at week 52;   Percentage changes from baseline in High-Density Lipoprotein-Cholesterol (HDL-C) at week 52;   Percentage changes from baseline in Low-Density Lipoprotein-Cholesterol (LDL-C) at week 52;   Percentage changes from baseline in uric acid at week 52
6 Recruiting The Additive Anti-inflammatory Effect of Simvastatin in Combination With Inhaled Corticosteroids on p38 MAPK in Asthma
Condition: Asthma
Interventions: Drug: Simvastatin;   Drug: B1-6-12
Outcome Measures: Sputum eosinophils;   Phosphorylated p38 MAPK in sputum cells
7 Recruiting Stroke Treatment With Acute Reperfusion and Simvastatin
Condition: Stroke, Acute
Intervention: Drug: Simvastatin
Outcome Measures: The primary outcome of this study is to determine whether simvastatin treatment started within the first 12 hours from stroke onset improves neurological and functional outcomes, evaluated at seventh day/discharge or at the third month.;   The secondary outcome of this study is to demonstrate that simvastatin is safe and not associated with higher rates of hemorrhagic transformation in patients who receive thrombolysis.
8 Recruiting Simvastatin Addition for Patients With Recent-onset Schizophrenia
Conditions: Schizophrenia;   Schizoaffective Disorder;   Schizophreniform Disorder;   Psychosis NOS
Interventions: Drug: Simvastatin;   Drug: Placebo
Outcome Measures: Change in Positive And Negative Syndrome Scale (PANSS) total score;   Change in PANSS positive, negative and general psychopathology scale scores;   Change in Global Assessment of functioning scale (GAF) score;   Change in cognitive functioning;   Presence and severity of metabolic syndrome;   Change in presence and severity of movement disorders using validated scales
9 Recruiting Efficacy Study of SIMVASTATIN to Treat Chronic Rhinosinusitis After Failure of Optimal Treatment
Condition: Rhinosinusitis
Intervention: Drug: SIMVASTATIN
Outcome Measures: Sino-Nasal symptomatology;   Bacterial culture;   Assessemt of liver and kidney functions;   RNA measurement of inflammatory biomarkers;   Sinus-Specific Quality of Life (22 questions Sino-nasal outcome test; SNOT-22);   Aspect of sinus mucosa aspect assessed by sinus endoscopy
10 Recruiting Effects of Simvastatin on Biomarkers
Condition: Alzheimer's Disease
Interventions: Drug: Simvastatin;   Drug: Placebo
Outcome Measures: Cerebral Spinal Fluid Biomarker measurements;   Measures of inflammation or oxidative stress in cerebral spinal fluid.
11 Not yet recruiting The Short-term Effects of Simvastatin on the Vision of Males Affected by Choroideremia
Condition: Choroideremia
Intervention: Drug: Simvastatin
Outcome Measures: Full-field scotopic threshold;   Microperimetry, OCT, fundus autofluorescence, ERG, VA
12 Unknown  Simvatstatin Used to Treat Pulmonary Hypertension
Condition: Hypertension, Pulmonary
Intervention: Drug: simvastatin
Outcome Measures: the simvastatin can alleviate pulmonary hypertension;   pulmonary pressure;   simvastatin can highten the perioperative and long term survaval rate and the living quality
13 Recruiting Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Drug: Simvastatin
Outcome Measures: Vaso-occlusive pain events;   Correlation of plasma biomarkers with clinical measures of vaso-occlusive pain;   Clinical safety of simvastatin
14 Unknown  Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin.
Conditions: Diabetes Mellitus;   Hypertension
Interventions: Drug: atrorvastatin 10mg;   Drug: simvastatin 40mg
Outcome Measures: Reduction in oxLDL levels;   Reduction in plasma malondialdehydes and urine isoprostanes;   Reduction in plasma endothelial function parameters such as soluble Vascular Adhesion Molecule (sVCAM) and von Willebrand factor
15 Unknown  Effects of Nicotinic Acid Plus Simvastatin Versus Simvastatin Alone on Carotid and Femoral Intima-Media Thickness in Patients With Peripheral Artery Disease (NASCIT)
Conditions: Dyslipidemia;   Atherosclerosis
Interventions: Drug: simvastatin;   Drug: Nicotinic Acid
Outcome Measures: change of carotid and femoral IMT from baseline to 6 and 12 months follow up and occurrence of major adverse cardiovascular events (MACE);   changes of grey scale median (GSM) score from baseline to follow-up, and changes of serum levels of total cholesterol, low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), triglycerides and lipoprotein (a).
16 Recruiting Simvastatin Augmentation of Lithium Treatment in Bipolar Depression
Condition: Bipolar Disorder
Interventions: Drug: Simvastatin;   Drug: Placebo
Outcome Measure: Change in MADRS (4 weeks)
17 Unknown  Pilot Mouthwash Study of Pioglitazone and Simvastatin in Healthy Volunteers
Conditions: Cystic Fibrosis;   Anti Inflammatory Non-Steroidal;   Neutrophils
Interventions: Drug: Pioglitazone;   Drug: Simvastatin;   Drug: Ibuprofen
Outcome Measure: Neutrophil delivery to the oral mucosa using a noninvasive mouth wash technique
18 Recruiting Simvastatin for mTBI
Condition: TBI-Traumatic Brain Injury
Interventions: Drug: simvastatin;   Drug: placebo
Outcome Measures: cerebrospinal fluid (CSF) tau concentration;   Concentration of cerebrospinal fluid (CSF) Brain-derived neurotrophic factor (BDNF)
19 Recruiting Sarilumab Effect on the Pharmacokinetics of Simvastatin
Condition: Rheumatoid Arthritis
Interventions: Drug: sarilumab SAR153191 (REGN88);   Drug: simvastatin
Outcome Measures: Assessment of PK parameters - area under curve from zero time until the last measurable concentration (AUClast) and AUC for simvastatin;   Assessment of PK parameters - maximum concentration (Cmax), time to maximum concentration (tmax), and terminal half-life associated with the terminal slope (t1/2z) for simvastatin;   Assessment of PK parameters - Cmax, AUClast, AUC, tmax, t1/2z for simvastatin acid;   Number of participants with adverse events
20 Recruiting Simvastatin Effect on Radiation Therapy of Brain Metastases
Condition: Brain Metastases
Interventions: Drug: simvastatin in addition to radiation therapy;   Radiation: radiation therapy
Outcome Measures: a- Response rate;   progression free and overall survival;   adverse effects