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COMA and Gabapentin

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COMA Symptoms and Causes

A Coma is a deep state of unconsciousness. An individual in a Coma is alive but unable to move or respond to his or her environment. Coma may occur as a complication of an underlying illness, or as a result of injuries, such as brain injury.

A Coma rarely lasts more than 2 to 4 weeks. The outcome for Coma depends on the cause, severity, and site of the damage. People may come out of a Coma with physical, intellectual, and psychological problems. Some people may remain in a Coma for years or even decades. For those people, the most common cause of death is infection, such as pneumonia.

NIH: National Institute of Neurological Disorders and Stroke

Check out the latest treatments for COMA

COMA treatment research studies

Gabapentin clinical trials, surveys and public health registries


Find Drug Side Effect reports



Gabapentin Side Effects

Completed Suicide (332)
Dizziness (329)
Somnolence (306)
Pain (288)
Headache (282)
Confusional State (265)
Nausea (256)
Off Label Use (227)
Tremor (223)
Fatigue (221)
Depression (214)
Fall (194)
Convulsion (184)
Feeling Abnormal (183)
Toxicity To Various Agents (176)
Suicidal Ideation (171)
Malaise (171)
Respiratory Arrest (163)
Cardiac Arrest (145)
Condition Aggravated (144)
Dyspnoea (113)
Pain In Extremity (112)
Myoclonus (108)
Anxiety (108)
Asthenia (107)
Amnesia (104)
Diarrhoea (102)
Insomnia (97)
Vision Blurred (90)
Gait Disturbance (85)
Vomiting (84)
Death (84)
Oedema Peripheral (83)
Disorientation (82)
Back Pain (80)
Rash (80)
Weight Increased (79)
Agitation (78)
Paraesthesia (74)
Memory Impairment (73)
Dyskinesia (73)
Abdominal Pain (73)
Hallucination (72)
Muscular Weakness (71)
Sedation (71)
Myalgia (70)
Loss Of Consciousness (70)
Renal Failure Acute (69)
Hypoaesthesia (66)
Muscle Spasms (66)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

Be careful! Avoid Gabapentin at all costs! My mother's doctor ordered a 900 mg/day dose. In the 2 years she was under this dose, she fell 5 times! No doctor 'suspected' this drug! Then, he increased the dose to...1800 mg/day! I almost lost her! I am

Citalopram caused me to suffer acute-closed angle Glaucoma CAG,

Diagnosis and treatment began at age 44 and the pressure was well controlled until the last two years at age 66. In 2003 I suffered a concussion along with other events which worsened depressive episodes. In 2004 I began Celexa an

Dose Gabapantin have any ting to do with the nearves in your body

For the last two weeks I have been taking a lowish dose of Gabapentin for night-time nerve pain (100gm three times a day and then 200mg at night.) It has worked brilliantly for the pain and I was ecstatic BUT I have now wet the bed two nights in a r

GABAPENTIN noticed that medication got worsen n Nurgloist n don't listin. My problem n even rash n stomach ach n was getting stress out n decided go different doctor n was. Going take that chance with my n stop going to Nurgloist n been two.n bo

Great so far for my anxiety... just side effects has ... sexually saticfied,nausea little bit.. dizzynezz! lolz.. but great medication/ i think..

Having racing thoughts and unmotivated *DONT_KNOW*

Hear voices

Hello, I've been taking a cocktail of meds for 9 years to help treat acute nerve pain from a severe Brachial Plexus nerve avulsion C 7, 8, T1 and Spinal cord injury. Medications: Gabapentin 3600 mg., Methadone 100 mg. , Baclofen 20 mg. every 8 hour

Adela, por favor haga ejercicio y no coma comida chatarra en vez de tomar estas pastillas. Los efectos secundarios son muy feos, para bajar de peso, las pastillas son lo peor, haga las cosas naturalmente o su higado va a pagar un precio muy alto, las

At the end of my first Csection, I was wide awake until they gave me methergine...i was suddenly very nauseous, then passed out for a few hours. i had 3 more c-sections with same immediate reaction to the methergine, only each time my 'coma

Coma causing motor cycle accident. brain damage. family difficulties not being able to work causing financial problems

I performed CPR on my brother yesterday. We don't yet know his condition at the hospital, due to the medicated coma, and the hypo (?) something!

Impaired work ability, mood swings, mental disorder, weight loss probabily because my while family has been goung through stuff I would wish on one-one. My Mon just got out of another coma recently and I thought with all my heart that this depakote r

Incurred skull fracture that req'd a NeuroSurgeon in 1971 (15 yrs old)- coma, amnesia, anticonvulsant meds - learned how to walk/talk & remember who people were quite quickly. Was diagnosed with deep depression at age 25 (

Ive been on epilim cr 500 three times a day since having a traumatic head injury following a traffic accident between my bike and a car which wasn't my fault! After two weeks in a coma, two weeks being a bit dopey in hospital an a further two months

Lobivon prescribed. Last night suffered hypodiabetic coma Would it be benefiical not to take today

My cousin who is 45 liver shut down. His liver is non-functional, he is in a coma and needs a liver transplant.

My sister is in a diabetic coma she is now off life support but it has been almost 2 weeks what are the chances of recovery. they have said that the eeg shows no brain damage but 'slowing'

COMA Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Longitudinal Study of the Default-mode Network Connectivity in Brain Injured Patients Recovering From Coma
Condition: Coma
Intervention:
Outcome Measures: Change of DMN resting state fMRI connectivity between 1 and 2 month after severe brain injury;   Compare functional and structural DMN connectivity between 1 and 2 month after severe brain injury
2 Recruiting Study of Conscious Behavior Under Low-frequency Deep Brain Stimulation in Chronic and Severe Post-Coma Disorders of Consciousness
Condition: Chronic and Severe Post-Coma Disorders of Consciousness (Permanent Vegetative State, Minimally Conscious State)
Intervention: Other: Implantable neurostimulation system
Outcome Measures: CRS-R scores (Coma Recovery Scale-Revised);   signs of awakening at night;   zerit burden interview
3 Recruiting Evaluation of Mechanisms Responsible for Coma in Patients Affected by Fulminant, Acute and Chronic Hepatic Failure
Condition: Acute and Chronic Hepatic Failure With Developing Coma
Intervention:
Outcome Measure: The relationship that exist between a liver undergoing chronic or acute degeneration and hepatic Coma.
4 Recruiting Syndrome and Aspiration Pneumonia in Intensive Care
Conditions: ICU Patients;   Under Mechanical Ventilation;   In State of Coma (Define by Glasgow < 8);   No Antibiotic Treatment
Intervention:
Outcome Measures: Determine the frequency of bacterial pneumonia in patients admitted to the ICU for Coma and treated with mechanical ventilation;   Quantify the use of antibiotics during the ICU stay for patients admitted to the ICU for Coma and treated with mechanical ventilation;   Description of the bacterial flora identified in respiratory specimens.;   Identification of predictive factors for development of bacterial pneumonia
5 Not yet recruiting Special Imaging Technique to Aid in the Diagnosis of Patients in Coma After Cardiac Arrest
Condition: Brain Death
Intervention: Procedure: Computed tomography perfusion
Outcome Measures: Clinical evaluation of brainstem function;   Number of adverse events as a measure of safety and tolerability
6 Unknown  Clinical Study of the LRS ThermoSuit™ System in Post Arrest Patients With Intravenous Infusion of Magnesium Sulfate
Conditions: Death, Sudden, Cardiac;   Coma
Interventions: Device: Cooling with ThermoSuit with Magnesium Sulfate Infusion;   Device: Cooling with ThermoSuit with Normal Saline Infusion
Outcome Measures: Cooling rate from start of cooling until a temperature of 34°C is reached;   Time from collapse to a core temperature < 34.0°C;   Percentage of time of the maintenance phase where the patient core temperature is between 32.0 and 34.0°C.;   Incidence of shivering during cooling and maintenance of hypothermia;   Duration of maintenance of hypothermia without supplemental cooling;   Total number of days in ICU;   Neurologic and physical status;   Adverse events, serious adverse events, device-related adverse events;   Blood pressure and ECGs;   Serum chemistry parameters (standard chemistry panel);   Hematology parameters;   Survival;   Rate of infection (respiratory, skin, and invasive access sites) and rate of sepsis
7 Not yet recruiting Cognitive Auditory Evoked Potential After Cardiac Arrest: Interest of Mismatch negativiTY
Conditions: Coma;   Cardiac Arrest
Intervention: Procedure: Auditory-evoked potentials
Outcome Measures: CPC score of 1 or 2 (favorable outcome);   Awakeness;   Time of realization of the cortical auditory-evoked potential;   CPC score of 1 or 2 at ICU discharge;   Length of mechanical ventilation, ICU stay, hospital stay and vital status at discharge;   CPC score of 1 or 2 at hospital discharge
8 Unknown  Thalamic Stimulation of Patients in Vegetative or Minimally Conscious State
Conditions: Vegetative State;   Minimally Conscious State
Intervention: Device: Implantable neurostimulation system (Medtronic)
Outcome Measures: Efficacy of thalamic stimulation evaluated by the administration of the CRS-R and Coma/Near Coma scales and comparing the results obtained with those of the pre-implant evaluation.;   Changes in the length of desynchronization performed by continuous EEG recording and spectral analysis. Evaluate which patients in Vegetative State and Minimally Conscious State can benefit from central thalamic stimulation.
9 Recruiting The MENDS II Study
Conditions: Sepsis;   Delirium;   Impaired Cognition
Interventions: Drug: Dexmedetomidine;   Drug: Propofol
Outcome Measures: Delirium/Coma Free Days (DCFDs);   Ventilator-free days (VFDs);   90-day Survival;   Decrease incidence and severity of long-term cognitive impairment;   Markers of Inflammation;   Secondary Infections;   Organ Dysfunction;   Acute Respiratory Distress Syndrome
10 Not yet recruiting Finding the Optimal Cooling tempeRature After Out-of-HoSpiTal Cardiac Arrest
Condition: Out-Of-Hospital Cardiac Arrest.
Interventions: Device: Target Temperature Management of 34°C;   Device: Target Temperature Management of 32°C;   Device: Target Temperature Management of 33°C
Outcome Measures: Fraction of subjects surviving with good neurologic outcome(modified Rankin Score (mRS) ≤ 3) at 90 days after out-of-hospital cardiac arrest.;   Fraction of subjects with good neurologic outcome (mRS ≤ 3) at discharge after out-of-hospital cardiac arrest;   Identify possible covariates influencing survival with good neurological outcome.;   To assess safety with each target temperature with regard to bleeding, infection, renal impairment, hypokalemia and arrhythmia.
11 Recruiting Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young Infants
Conditions: Urea Cycle Disorders;   Organic Acidemias
Interventions: Other: Therapeutic Hypothermia;   Other: Standard of care therapy
Outcome Measures: Number of Participants with unexpected Serious Adverse Events as a Measure of Safety and Tolerability;   Feasibility of hypothermia therapy as adjunct therapy to the complex standard of care therapy;   Time to normalization of ammonia level
12 Unknown  Vagus Nerve Stimulation to Augment Recovery From Minimally Conscious or Persistently Vegetative States After Traumatic Brain Injury
Conditions: Minimally Conscious States Due to Traumatic Brain Injury;   Persistently Vegetative States Due to Traumatic Brain Injury
Interventions: Device: Vagus nerve stimulation;;   Device: No stimulation
Outcome Measures: JFK Coma Recovery Scale;   FIM plus FAM;   functional MRI
13 Recruiting Mechanical Ventilation in Brain-injured Patients
Conditions: Brain-injury;   Stroke;   Subarachnoid Haemorrhage;   Traumatic Brain Injury;   Structural Coma
Intervention:
Outcome Measures: Mechanical ventilatory free days;   Mortality;   In-ICU mortality;   Duration of mechanical ventilation;   ICU free days at day 90;   Acute respiratory distress syndrome / acute lung injury;   Hospital acquired pneumonia;   Blood gaz;   Intracranial pressure;   Glasgow outcome scale;   Extubation failure;   Ventilatory setting
14 Recruiting Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Mechanical Ventilation
Conditions: Critical Illness;   Respiration, Artificial
Interventions: Procedure: Non-sedation for intubated, mechanically ventilated patients;   Procedure: Controlgroup, sedation with daily wake-up trial
Outcome Measures: Mortality;   Days until death;   Cardiovascular event;   Coma and deliriumfree days;   RIFLE-score;   Days until discharge;   Days until the participant is without mechanical ventilation
15 Recruiting Evaluation of the Efficacy and Safety of Inhaled Nitric Oxide as Adjunctive Treatment for Cerebral Malaria in Children
Condition: Cerebral Malaria
Interventions: Drug: inhaled nitric oxide;   Drug: Placebo
Outcome Measures: Angiopoietin 1 (Ang-1);   Mortality;   Coma score;   retinopathy;   tone;   Measure of occurrence of neurological sequelae in children;   Vital signs;   oxygen saturation
16 Recruiting Rehabilitation of Patients After Subarachnoid Hemorrhage
Condition: SAH
Intervention: Other: Early multidisciplinary rehabilitation
Outcome Measures: Glasgow Coma Scale (GCS);   Glasgow Outcome Scale Extended (GOSE);   Functional Independence Measure (FIM);   Coma Recovery Scale (CRS);   Disability Rating Scale (DRS);   High Level Mobility Assessment Tool (HIMAT)
17 Recruiting Acupuncture for Severe Head Injury
Condition: Head Injury
Interventions: Other: acupuncture;   Other: laser acupuncture;   Other: control
Outcome Measure: Glasgow Coma scale and muscle power
18 Unknown  Effectiveness and Safety of Angongniuhuang Pill on Restoring Consciousness for Patients Who Have Suffered From a Stroke
Conditions: Stroke;   Acute Ischemic Stroke
Interventions: Drug: Angongniuhuang Pill;   Drug: placebo
Outcome Measures: Glasgow Coma Scale (GCS) within 90 days after stroke onset.;   The percentage of patients of different consciousness level stratified according to the GCS, and the time spent of patients who recovered from Coma.;   Global disability on modified Rankin scale at 90 days.;   NIH stroke scale;   Changes in laboratory indexes as safety assessment, including red blood cell(RBC), white blood cell(WBC), platelet(PLT), alanine transarninase(ALT), aspartate transarninase (AST), blood urea nitrogen (BUN), creatinine(Cr) in blood samples; protein, red b
19 Recruiting The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) Study
Conditions: Delirium;   Impaired Cognition;   Long Term Psychologic Disorders
Interventions: Drug: Haloperidol;   Drug: Ziprasidone;   Drug: Placebo
Outcome Measures: Delirium/Coma-free days;   Survival;   Delirium duration;   ICU length of stay;   Hospital length of stay;   Ventilator-free days;   ICU readmission;   Hospital readmission;   Neuropsychological dysfunction;   Quality of life;   Posttraumatic stress disorder;   QTc prolongation;   Extrapyramidal symptoms;   Neuroleptic malignant syndrome
20 Recruiting Performance Evaluation of Pupillary Reactivity in Monitoring of Brain-damaged Patients in Intensive Care
Condition: Brain-damaged Patients
Intervention: Other: pupillometry data
Outcome Measures: electronic pupillometer;   Glasgow Coma Score