CONSTIPATION and MEPROBAMATE

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CONSTIPATION Symptoms and Causes

Constipation means that a person has three or fewer bowel movements in a week. The stool can be hard and dry. Sometimes it is painful to pass. At one time or another, almost everyone gets constipated. In most cases, it lasts a short time and is not serious.

There are many things you can do to prevent Constipation. They include

Eating more fruits, vegetables and grains, which are high in fiber
Drinking plenty of water and other liquids
Getting enough exercise
Taking time to have a bowel movement when you need to
Using laxatives only if your doctor says you should
Asking your doctor if medicines you take may cause Constipation

It's not important that you have a bowel movement every day. If your bowel habits change, however, check with your doctor.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Check out the latest treatments for CONSTIPATION

➢ CONSTIPATION treatment research studies

➢ MEPROBAMATE clinical trials, surveys and public health registries

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MEPROBAMATE Side Effects

Toxicity To Various Agents (14)

Respiratory Arrest (6)

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Pulmonary Oedema (5)

Completed Suicide (5)

Death (5)

Loss Of Consciousness (4)

Depressed Level Of Consciousness (3)

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Fall (3)

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Hypothermia (3)

Pancreatitis Acute (3)

Circulatory Collapse (2)

Cardiomegaly (2)

Coma (2)

Dyspnoea (2)

Hypotension (2)

Drowning (2)

Convulsion (2)

Vomiting (2)

Malaise (2)

Injury (2)

Peripheral Ischaemia (2)

Oropharyngeal Pain (2)

Unresponsive To Stimuli (2)

Salivary Hypersecretion (2)

Neonatal Respiratory Distress Syndrome (1)

Normal Pressure Hydrocephalus (1)

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Lung Disorder (1)

Obesity (1)

Left Ventricular Hypertrophy (1)

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Intentional Self-injury (1)

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Pain In Extremity (1)

Overdose (1)

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Pallor (1)

Pelvic Inflammatory Disease (1)

Portal Triaditis (1)

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Premature Baby (1)

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Recent Reviews

Dziala i to jak......polecam

I had a problem tonight with my bowel movements. I hadn't passed one in 5 days. So I decided to force the stool out. Well it worked but The stool was rock hard and covered with blood. I felt sick. So I got a drink of water and went to bed. Here I am

I took dulcolax to relieve some constipation. I woke up at 3:00 in the morning with severe cramps. I felt like someone was stabbing me in the stomach. I went to the bathroom. I felt lightheaded and dizzy. Next thing I know I am coming out what I gues

Ive gone to my doctor coz of constipation, she gave me laxative but it really hurts, down there. And mostly it wants to come out and i force it back in because it wont come out anyway, and its useless trying to push It trys to come out but wont

My 9 year old daughter has been ill with flu, now she has not done a poo in 5 days, she in alot of pain and feels sick, need advice

The <a href='http://www.biblehealth.com/constipation/constipation-an-overview.html'>constipation</a> is also known as costiveness, dyschezia and dyssynergic defaecation. It refers to bowel movements that are infrequent or hard to pass. It

I am taking Suboxone and have had constipation, fatigue and very bad chills and sweats at night. Even during the day, I sometimes feel like I am hot and cold at the same time. I am wondering though, if this is Menopause? The fatigue is so extrem

I toke imodium 3 days ago 9th july 2010 and today is 12 july 2010 and I am scared now I have not been to toilet for three days, it suppose to help you with your diaherea and then gives you constipation may be the initial dose should be one

I ASKED MY GP FOR CHAMPIX AS I HAD SUDDENLY DECIDED AFTER SMOKING FOR 22YEARS. I TRIED PATCHES IN THE PAST ADN COLD TURKEY. PATCHES CAUSED CHEST PAIN, BLOOTING, CONSTIPATION,NAUSEA,SWEATS,

<strong>Constipation, Fluid build up under my eyes, Depressed</strong>

After having stilnoct for atleast 6 months, there is occuring of head heaviness,fever, dry mouth,constipation, lack of appetite.

After taking it for two days it createde a lot of stomach problems, belching, acidity, bloating, constipation and what not.

Am taking klonopin for restless leg syndrome (1 mg. at night) this causese debilitating daytime fatigue and constipation

Back pains,dizziness,constipation and stomach pains

Beano contains Magnesium Stearate. Magnesium Stearate is toxic.Now wonder some of you had diarrhea,stomach pains,and constipation.Magnesium Stearate will suppress the immune system.No thanks beano,I would rather fart!!

Been taking 3x the recommended dose of Pepto-Bismol because I always have constipation. what are your veiws of me taken Pepto Bismol for constipation? What might some other options be?And Pepto- bismol is not really even medicine what would you respo

CONSTIPATION Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.

Rank

Status

Study

Not yet recruiting

Innovative Toilet Seat Test for Patients With Symptoms of Constipation and/or Emptying Disorders

Condition:	Constipation
Interventions:	Device: Experimental toilet seat; Device: Standard toilet seat
Outcome Measures:	Improvement in bowel movement frequency; Improvement in quality of life

Recruiting

Lactobacillus Reuteri in Treatment of Functional Abdominal Pain and Chronic Constipation in Children

Conditions:	Abdominal Pain; Constipation - Functional
Interventions:	Dietary Supplement: Administration of L.reuteri in children with abdominal pain; Dietary Supplement: Administration of placebo in children with abdominal pain; Dietary Supplement: Administration of L.reuteri in children with Constipation; Dietary Supplement: Administration of placebo in children with Constipation
Outcome Measures:	Intensity of abdominal pain; Severity of chronic Constipation; Intensity of abdominal pain after treatment; Severity of chronic Constipation after treatment

Recruiting

Perineal Self-Acupressure

Conditions:	Chronic Constipation; Constipation; Hemorrhoids
Interventions:	Behavioral: Perineal Self-Acupressure; Behavioral: Educational Control
Outcome Measures:	Patient Assessment of Constipation Quality of Life Questionnaire; Modified Bowel Function Index and Hemorrhoid Questionnaire; SF-12

Not yet recruiting

A Trial of Three Types of Enemas Used to Treat Functional Constipation in Children

Condition:	Functional Constipation
Interventions:	Drug: Sodium phosphate enema; Drug: Normal saline enema; Drug: Mineral oil enema
Outcome Measure:	Change in pain scores following administration of enema

Unknown ^†

Lubiprostone in Patients With Multiple Sclerosis Associated Constipation

Conditions:	Multiple Sclerosis; Constipation
Interventions:	Drug: Lubiprostone; Drug: Placebo
Outcome Measures:	To determine the effect of lubiprostone 24 mcg twice daily on spontaneous bowel movements in patients with MS-associated Constipation; To determine the safety of lubiprostone based on adverse event (AE) type, frequency, and severity. Hypothesis: AE type, frequency, and severity will be comparable in lubiprostone and placebo treated patients.

Recruiting

Functional Magnetic Stimulation Enhances Gastrointestinal Motility in Patients With Chronic Constipation

Condition:	Constipation
Intervention:	Device: Functional Magnetic Stimulation
Outcome Measures:	Effectiveness of FMS in accelerating the gastric emptying in patients with non-neurological Constipation after 5-week conditioning protocol; Effectiveness of FMS in reducing the colonic transit time in patients with non-neurological Constipation after a 5 week conditioning period

Recruiting

A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation

Condition:	Constipation
Intervention:	Dietary Supplement: Natural Fibre Supplement
Outcome Measures:	Number of bowel movements per week; Stool consistency, as measured by the Bristol Stool Form Scale; Quality of life as measured by the Quality of Life Questionnaire (PAC-QOL); Constipation symptoms as measured by PAC-SYM; Laxative use by subjects with functional Constipation

Not yet recruiting

Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation

Condition:	Constipation
Interventions:	Drug: Naloxone; Drug: Placebo
Outcome Measures:	Severity of Constipation symptoms; Severity of opioid withdrawal symptoms

Recruiting

MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery

Condition:	Post Procedural Constipation
Interventions:	Drug: MiraLax; Drug: Placebo; Drug: Rescue Laxative
Outcome Measures:	Time to first postoperative bowel movement; Other postoperative medication use; Evaluation of symptoms and quality of life related to Constipation; Symptoms of Over-Effectiveness; Evaluation of symptoms and quality of life related to Constipation 6-weeks postoperatively

Recruiting

Trial on Short-chain Fructooligosaccharides, Microbiota, and Constipation in Adults

Condition:	Functional Constipation
Interventions:	Dietary Supplement: sc-FOS 2g/day; Dietary Supplement: sc-FOS 4g/day; Dietary Supplement: sc-FOS 8g/day; Dietary Supplement: Placebo
Outcome Measures:	Stool frequency (Number of complete bowel movements per day); Stool consistency (Bristol Stool Scale); Severity of symptoms (Constipation Scoring System; CSS); Quality of Life (Patient Assessment of Constipation Quality of Life; PAC-QoL)

Recruiting

Reflexology for Chronic Constipation

Condition:	Chronic Constipation
Intervention:	Procedure: Reflexology
Outcome Measures:	Change in complete spontaneous bowel movements (CSBM)/week from baseline to 24 weeks; Increase of at least one CSBM per week from baseline for 9 or more weeks during the 24-week treatment period; Stool frequency/Week (CSBMs and spontaneous bowel movements (SBMs); Stool consistency/week using the 7- point Bristol Stool Form Scale, during the 24 weeks of the study period; Severity of straining using a 5-point ordinal scale (1 indicates not at all; 5 an extreme amount).; Abdominal discomfort, using a 5-point ordinal scale (1 indicates not at all; 5 an extreme amount); Severity of bloating, using a 5-point ordinal scale (1 indicates not at all; 5 an extreme amount); Constipation severity (using a 5-point ordinal scale, with higher scores indicating greater severity); Constipation relief (based on a 7-point balanced scale, with 1 indicating complete relief, 4 indicating no change, and 7 indicating very severe Constipation); Satisfaction with the trial results, using a 5-point ordinal scale; Health related quality of life (using the validated Patient Assessment of Constipation Quality of Life instrument (PAC-QOL); Treatment side effects

Unknown ^†

Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation.

Condition:	Chronic Constipation, Methanogenesis
Interventions:	Drug: Lubiprostone; Drug: Lubiprostone Control
Outcome Measure:	Effect of Lubiprostone in patients with Chronic Constipation

Unknown ^†

Multistrain Probiotic for Functional Constipation

Condition:	Functional Constipation
Interventions:	Dietary Supplement: High dose Multistrain probiotic, 100 billion cfu/day; Dietary Supplement: Low dose Multistrain probiotic, 15 billion cfu/day
Outcome Measures:	Whole gut transit time; Patient Assessment of Constipation Quality of Life (PAC-QOL); Wexner Constipation Score (WCS); Gastrointestinal Symptom Rating Scale (GSRS); Stool frequency; Stool consistency; Fecal probiotic count; Adverse events

Recruiting

Effectiveness of Standing Frame on Constipation in Children With Cerebral Palsy

Conditions:	Cerebral Palsy; Quadriplegia; Diplegia; Constipation
Intervention:	Device: standing-frame
Outcome Measures:	bowel evacuation frequency; Bowel evacuation inductions frequency

Recruiting

The Efficacy and Safety Study of Electro-acupuncture for Severe Chronic Functional Constipation

Condition:	Constipation
Interventions:	Device: electro-acupuncture; Device: sham electro-acupuncture
Outcome Measures:	Change of weekly average CSBM from baseline; The proportion of participants having three or more CSBMs on average per week; Change of weekly average CSBMs from baseline; Change of weekly average SBMs from baseline; Change of average weekly stool consistency assessment from baseline; Change of average weekly degree of difficulty in defecation from baseline; PAC-QOL; incidence of adverse events; Usage of medicine for Constipation

Recruiting

Quality of Life in Children and Adolescents With Chronic Functional Constipation: Educational Action Effects

Condition:	Chronic Functional Constipation
Intervention:	Behavioral: Educational action with focal group
Outcome Measures:	The improvement in the quality of life on participants after the intervention; The improvement in clinical parameters of chronic functional Constipation

Recruiting

Efficacy of Sacral Nerve Modulation in Severe Refractory Constipation

Condition:	Constipation
Intervention:	Procedure: sacral nerve modulation
Outcome Measures:	Percentage of patients showing a positive response to sacral nerve stimulation at 2 months; Clinical characteristics, manometry data, Wexner score of responders to stimulation during the temporary stimulation test (period before the permanent implantation); Clinical characteristics, manometry data, Wexner score of responders to short-term stimulation; Efficacy of neuromodulation; Manometry data, Wexner, QoL and EVA scores, time of colonic transit of responders to prolonged stimulation; To evaluate the investigator opinion about the neuromodulation response, using the patient diary.

Recruiting

Maintenance Treatment for Children With Constipation

Condition:	Constipation
Interventions:	Drug: Polyethylene glycol 3350; Other: Placebo
Outcome Measures:	Treatment recovery; Usage of laxative

Unknown ^†

Pilot Study of the Effect of Lactulose on Post Caesarean Section Constipation

Conditions:	Constipation; Abdominal Pain; Nausea; Vomiting
Intervention:	Drug: Lactulose
Outcome Measures:	Time in hours to passage of first stool post Caesarean Section.; Frequency of abdominal pain between lactulose and non-lactulose groups.; Frequency of nausea and vomiting between lactulose and non-lactulose groups

Not yet recruiting

Assessing a Stool Symptom Screener in Patients With Chronic Opioid-Induced Constipation

Condition:	Opioid-induced Constipation
Intervention:
Outcome Measure:	Semi-structured discussion guide