Rank |
Status |
Study |
1 |
Not yet recruiting
|
Innovative Toilet Seat Test for Patients With Symptoms of Constipation and/or Emptying Disorders
Condition: |
Constipation |
Interventions: |
Device: Experimental toilet seat; Device: Standard toilet seat |
Outcome Measures: |
Improvement in bowel movement frequency; Improvement in quality of life |
|
2 |
Recruiting
|
Lactobacillus Reuteri in Treatment of Functional Abdominal Pain and Chronic Constipation in Children
Conditions: |
Abdominal Pain; Constipation - Functional |
Interventions: |
Dietary Supplement: Administration of L.reuteri in children with abdominal pain; Dietary Supplement: Administration of placebo in children with abdominal pain; Dietary Supplement: Administration of L.reuteri in children with Constipation; Dietary Supplement: Administration of placebo in children with Constipation |
Outcome Measures: |
Intensity of abdominal pain; Severity of chronic Constipation; Intensity of abdominal pain after treatment; Severity of chronic Constipation after treatment |
|
3 |
Recruiting
|
Perineal Self-Acupressure
Conditions: |
Chronic Constipation; Constipation; Hemorrhoids |
Interventions: |
Behavioral: Perineal Self-Acupressure; Behavioral: Educational Control |
Outcome Measures: |
Patient Assessment of Constipation Quality of Life Questionnaire; Modified Bowel Function Index and Hemorrhoid Questionnaire; SF-12 |
|
4 |
Not yet recruiting
|
A Trial of Three Types of Enemas Used to Treat Functional Constipation in Children
Condition: |
Functional Constipation |
Interventions: |
Drug: Sodium phosphate enema; Drug: Normal saline enema; Drug: Mineral oil enema |
Outcome Measure: |
Change in pain scores following administration of enema |
|
5 |
Unknown †
|
Lubiprostone in Patients With Multiple Sclerosis Associated Constipation
Conditions: |
Multiple Sclerosis; Constipation |
Interventions: |
Drug: Lubiprostone; Drug: Placebo |
Outcome Measures: |
To determine the effect of lubiprostone 24 mcg twice daily on spontaneous bowel movements in patients with MS-associated Constipation; To determine the safety of lubiprostone based on adverse event (AE) type, frequency, and severity. Hypothesis: AE type, frequency, and severity will be comparable in lubiprostone and placebo treated patients. |
|
6 |
Recruiting
|
Functional Magnetic Stimulation Enhances Gastrointestinal Motility in Patients With Chronic Constipation
Condition: |
Constipation |
Intervention: |
Device: Functional Magnetic Stimulation |
Outcome Measures: |
Effectiveness of FMS in accelerating the gastric emptying in patients with non-neurological Constipation after 5-week conditioning protocol; Effectiveness of FMS in reducing the colonic transit time in patients with non-neurological Constipation after a 5 week conditioning period |
|
7 |
Recruiting
|
A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation
Condition: |
Constipation |
Intervention: |
Dietary Supplement: Natural Fibre Supplement |
Outcome Measures: |
Number of bowel movements per week; Stool consistency, as measured by the Bristol Stool Form Scale; Quality of life as measured by the Quality of Life Questionnaire (PAC-QOL); Constipation symptoms as measured by PAC-SYM; Laxative use by subjects with functional Constipation |
|
8 |
Not yet recruiting
|
Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation
Condition: |
Constipation |
Interventions: |
Drug: Naloxone; Drug: Placebo |
Outcome Measures: |
Severity of Constipation symptoms; Severity of opioid withdrawal symptoms |
|
9 |
Recruiting
|
MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery
Condition: |
Post Procedural Constipation |
Interventions: |
Drug: MiraLax; Drug: Placebo; Drug: Rescue Laxative |
Outcome Measures: |
Time to first postoperative bowel movement; Other postoperative medication use; Evaluation of symptoms and quality of life related to Constipation; Symptoms of Over-Effectiveness; Evaluation of symptoms and quality of life related to Constipation 6-weeks postoperatively |
|
10 |
Recruiting
|
Trial on Short-chain Fructooligosaccharides, Microbiota, and Constipation in Adults
Condition: |
Functional Constipation |
Interventions: |
Dietary Supplement: sc-FOS 2g/day; Dietary Supplement: sc-FOS 4g/day; Dietary Supplement: sc-FOS 8g/day; Dietary Supplement: Placebo |
Outcome Measures: |
Stool frequency (Number of complete bowel movements per day); Stool consistency (Bristol Stool Scale); Severity of symptoms (Constipation Scoring System; CSS); Quality of Life (Patient Assessment of Constipation Quality of Life; PAC-QoL) |
|
11 |
Recruiting
|
Reflexology for Chronic Constipation
Condition: |
Chronic Constipation |
Intervention: |
Procedure: Reflexology |
Outcome Measures: |
Change in complete spontaneous bowel movements (CSBM)/week from baseline to 24 weeks; Increase of at least one CSBM per week from baseline for 9 or more weeks during the 24-week treatment period; Stool frequency/Week (CSBMs and spontaneous bowel movements (SBMs); Stool consistency/week using the 7- point Bristol Stool Form Scale, during the 24 weeks of the study period; Severity of straining using a 5-point ordinal scale (1 indicates not at all; 5 an extreme amount).; Abdominal discomfort, using a 5-point ordinal scale (1 indicates not at all; 5 an extreme amount); Severity of bloating, using a 5-point ordinal scale (1 indicates not at all; 5 an extreme amount); Constipation severity (using a 5-point ordinal scale, with higher scores indicating greater severity); Constipation relief (based on a 7-point balanced scale, with 1 indicating complete relief, 4 indicating no change, and 7 indicating very severe Constipation); Satisfaction with the trial results, using a 5-point ordinal scale; Health related quality of life (using the validated Patient Assessment of Constipation Quality of Life instrument (PAC-QOL); Treatment side effects |
|
12 |
Unknown †
|
Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation.
Condition: |
Chronic Constipation, Methanogenesis |
Interventions: |
Drug: Lubiprostone; Drug: Lubiprostone Control |
Outcome Measure: |
Effect of Lubiprostone in patients with Chronic Constipation |
|
13 |
Unknown †
|
Multistrain Probiotic for Functional Constipation
Condition: |
Functional Constipation |
Interventions: |
Dietary Supplement: High dose Multistrain probiotic, 100 billion cfu/day; Dietary Supplement: Low dose Multistrain probiotic, 15 billion cfu/day |
Outcome Measures: |
Whole gut transit time; Patient Assessment of Constipation Quality of Life (PAC-QOL); Wexner Constipation Score (WCS); Gastrointestinal Symptom Rating Scale (GSRS); Stool frequency; Stool consistency; Fecal probiotic count; Adverse events |
|
14 |
Recruiting
|
Effectiveness of Standing Frame on Constipation in Children With Cerebral Palsy
Conditions: |
Cerebral Palsy; Quadriplegia; Diplegia; Constipation |
Intervention: |
Device: standing-frame |
Outcome Measures: |
bowel evacuation frequency; Bowel evacuation inductions frequency |
|
15 |
Recruiting
|
The Efficacy and Safety Study of Electro-acupuncture for Severe Chronic Functional Constipation
Condition: |
Constipation |
Interventions: |
Device: electro-acupuncture; Device: sham electro-acupuncture |
Outcome Measures: |
Change of weekly average CSBM from baseline; The proportion of participants having three or more CSBMs on average per week; Change of weekly average CSBMs from baseline; Change of weekly average SBMs from baseline; Change of average weekly stool consistency assessment from baseline; Change of average weekly degree of difficulty in defecation from baseline; PAC-QOL; incidence of adverse events; Usage of medicine for Constipation |
|
16 |
Recruiting
|
Quality of Life in Children and Adolescents With Chronic Functional Constipation: Educational Action Effects
Condition: |
Chronic Functional Constipation |
Intervention: |
Behavioral: Educational action with focal group |
Outcome Measures: |
The improvement in the quality of life on participants after the intervention; The improvement in clinical parameters of chronic functional Constipation |
|
17 |
Recruiting
|
Efficacy of Sacral Nerve Modulation in Severe Refractory Constipation
Condition: |
Constipation |
Intervention: |
Procedure: sacral nerve modulation |
Outcome Measures: |
Percentage of patients showing a positive response to sacral nerve stimulation at 2 months; Clinical characteristics, manometry data, Wexner score of responders to stimulation during the temporary stimulation test (period before the permanent implantation); Clinical characteristics, manometry data, Wexner score of responders to short-term stimulation; Efficacy of neuromodulation; Manometry data, Wexner, QoL and EVA scores, time of colonic transit of responders to prolonged stimulation; To evaluate the investigator opinion about the neuromodulation response, using the patient diary. |
|
18 |
Recruiting
|
Maintenance Treatment for Children With Constipation
Condition: |
Constipation |
Interventions: |
Drug: Polyethylene glycol 3350; Other: Placebo |
Outcome Measures: |
Treatment recovery; Usage of laxative |
|
19 |
Unknown †
|
Pilot Study of the Effect of Lactulose on Post Caesarean Section Constipation
Conditions: |
Constipation; Abdominal Pain; Nausea; Vomiting |
Intervention: |
Drug: Lactulose |
Outcome Measures: |
Time in hours to passage of first stool post Caesarean Section.; Frequency of abdominal pain between lactulose and non-lactulose groups.; Frequency of nausea and vomiting between lactulose and non-lactulose groups |
|
20 |
Not yet recruiting
|
Assessing a Stool Symptom Screener in Patients With Chronic Opioid-Induced Constipation
Condition: |
Opioid-induced Constipation |
Intervention: |
|
Outcome Measure: |
Semi-structured discussion guide |
|