Rank |
Status |
Study |
1 |
Recruiting
|
Evaluation of a Stepped Care Approach to Manage Depression in Diabetes
Conditions: |
Major Depressive Disorder; Minor Depressive Disorder; Sub-Threshold Depression; Diabetes Mellitus |
Interventions: |
Behavioral: Step 1: Diabetes-Specific CBT (5 group sessions); Behavioral: Step 2: Depression-Specific CBT (6 single sessions); Behavioral: Step 3: Referral to Psychotherapist and/or Psychiatrist; Behavioral: Standard Diabetes Education |
Outcome Measures: |
Depressive Mood - Hamilton Rating Scale for Depression (HAMD); Diabetes-Related Distress - The Problem Areas in Diabetes Questionnaire (PAID); Psychological/ Emotional Well-Being - The WHO-5 Well-being Index (WHO-5); Health-Related Quality of Life - The Short Form-36 Health Survey (SF-36); Diabetes Self-Care Behavior - The Summary of Diabetes Self-Care Activities Measure (SDSCA); Glycaemic Control (HbA1c); Health-Related Quality of Life - The EuroQol-5D (EQ-5D); Diabetes Self-Care Behavior - The Diabetes Self-Management Questionnaire (DSMQ) |
|
2 |
Recruiting
|
Psychological Mindedness as a Predictor of Success in Cognitive Behavior Therapy for Depression
Conditions: |
Major Depressive Disorder; Dysthymia |
Intervention: |
Behavioral: Cognitive Behavior Therapy for Depression |
Outcome Measure: |
Level of Depression as measured by the Hamilton Rating Scale for Depression |
|
3 |
Recruiting
|
Depression Management at the Workplace
Condition: |
Depression |
Interventions: |
Other: Depression Product Detailing; Other: Depression HEDIS detailing |
Outcome Measures: |
employer purchase of Depression management product; fidelity of Depression management model purchased to evidence-based models |
|
4 |
Recruiting
|
New Clinical Applications for Internet-based Cognitive Behavior Therapy for Insomnia and Depression
Conditions: |
Insomnia; Major Depression; Minor Depression |
Interventions: |
Behavioral: Therapist guided Internet-CBT for insomnia w. extra support; Behavioral: Therapist guided Internet-CBT for insomnia; Behavioral: Therapist guided Internet-CBT for insomnia and Depression; Behavioral: Therapist Guided Internet-CBT for Depression plus insomnia placebo |
Outcome Measures: |
Change (from baseline) in Insomnia Severity Index (ISI); Change (from baseline) in Montgomery Asberg Depression Rating Scale, MADRS-S; Change (from baseline) in Sleep Diary; Changes (from baseline) in Actigraph data; Change (from baseline) in Trimbos and Institute of Medical Technology Assessment Cost Questionnaire for Psychiatry (TIC-P); Change (from baseline) in Cognitive functioning; Change (from baseline) in EuroQuol. EQ-5D; Change (from baseline) in Sheehan Disability Scale; Change (from baseline) in Clinical Outcome in Routine Evaluation - 10, CORE-OM |
|
5 |
Not yet recruiting
|
Blended Collaborative Care for Heart Failure and Co-Morbid Depression
Conditions: |
Heart Failure, Systolic; Depression; Cardiovascular Disease |
Interventions: |
Behavioral: Collaborative Care for Heart Failure; Behavioral: Collaborative Care for Depression |
Outcome Measures: |
Medical Outcomes Study (MOS) 12-Item Short Form Health Survey Mental Component Summary (SF-12 MCS); Kansas City Cardiomyopathy Questionnaire (KCCQ-12); Hamilton Rating Scale for Depression (17-Item); Incidence of Rehospitalization; Mortality; Health Care Costs; Employment |
|
6 |
Recruiting
|
Prevalence Study of Depression in Chinese Patients With Type 2 Diabetes (HK13)
Conditions: |
Diabetes; Depression |
Interventions: |
Other: Psychiatrist Interview; Other: Depression screening - control |
Outcome Measures: |
Depression and psychological well-being; Percentage of patients who attain 2 or more of the 'ABC' targets; Self care and Efficacy; Quality of life |
|
7 |
Recruiting
|
Can Genetics Predict Treatment Response to a Computerized Self-help Program for Depression?
Conditions: |
Major Depressive Disorder; Mood Disorders |
Intervention: |
Behavioral: Computerized self-help program for Depression |
Outcome Measures: |
Quick Inventory of Depressive Symptomatology (Self-Report) (QIDS-SR-16); Hamilton Depression Rating Scale (HAM-D); Inventory of Depression and Anxiety Symptoms (IDAS); Psychiatric Diagnostic Screening Questionnaire (PDSQ); Risky Families Questionnaire (RFQ); Massachusetts General Hospital Antidepressant Treatment History Questionnaire (ATRQ); Sheehan Disability Scale (SDS) |
|
8 |
Recruiting
|
Management of Depression in Primary Care
Condition: |
Depression |
Intervention: |
Behavioral: Structured patient-centered follow up of Depression |
Outcome Measures: |
Change in Depressive symptoms; Change in Quality of life; Prescriptions for antidepressants; Change in Activity/work ability; sick-listing data |
|
9 |
Unknown †
|
Low Intensity Versus Self-guided Internet-delivered Psychotherapy for Major Depression
Condition: |
Depression |
Interventions: |
Other: Low Intensity Internet-delivered psychotherapy; Other: Self-guided Internet delivered psychotherapy; Other: Improved treatment as usual |
Outcome Measures: |
Severity of depressive symptomatology measured by Beck Depression Inventory II; Socio-demographic variables.; Mini-International Neuropsychiatric Interview (MINI).; EuroQoL-5D questionnaire (EQ-5D - Spanish version); Client Service Receipt Inventory - adapted (CSRI - Spanish version); Overall Depression Severity and Impairment Scale; Positive and Negative Affect Scale (PANAS); Credibility/expectancy questionnaire |
|
10 |
Recruiting
|
Study of Web- Based Cognitive Behavioral Therapy for Depressed Korean Adolescents
Conditions: |
Depression; Mental Disorder in Adolescence; Cognitive Behavioral Therapy |
Interventions: |
Behavioral: web-based CBT; Behavioral: supportive care |
Outcome Measures: |
The Center for Epidemiological Studies of Depression (CES-D) Scale; Subjective depressed mood scale; The Korean youth self report (K-YSR); Acceptability and adherence of Web-based cognitive behavioral treatment program for adolescents with Depression; satisfaction of Web-based cognitive behavioral treatment program of both adolescents with Depression and their parents; Columbia suicide severity rating scale; Adolescent's characteristics that moderate the impact of the program |
|
11 |
Not yet recruiting
|
Healthy Moms-Healthy Kids: Reducing Maternal Depression for Better Outcomes in Head Start Children
Conditions: |
Maternal Depression; Parenting Behavior; Health; Interpersonal Relationships; Goal Directed Behavior,; Child Behavior; Child School Readiness |
Intervention: |
Behavioral: Interpersonal Psychotherapy for Depression -Group |
Outcome Measure: |
Beck Depression Inventory |
|
12 |
Not yet recruiting
|
A Family Depression Prevention Program
Condition: |
Depression |
Interventions: |
Behavioral: Family Cognitive Behavioral Prevention; Behavioral: Written information |
Outcome Measures: |
In children, the primary outcome is onset of a depressive episode. In parents, the primary outcome is time in a depressive episode.; Parents: Patient Health Questionnaire - 9 (PHQ-9); Children: Youth Self-report (YSR) anxiety/Depression subscale |
|
13 |
Unknown †
|
Outcome of Postnatal Depression Screening Using Edinburgh Postnatal Depression Scale
Condition: |
Depression, Postpartum |
Intervention: |
Procedure: Edinburgh Postnatal Depression Scale |
Outcome Measures: |
Mother's mental health at 6 months postpartum, as measured on the EPDS and General Health Questionnaire-12 (GHQ-12), both being self-report questionnaires.; Mother's parenting stress (measured by the Parenting Stress Index, a self-report questionnaire); Marital relationship satisfaction (measured by the Chinese Kansas Marital Satisfaction Scale, a self-report questionnaire); Marital status and employment status (both father and mother, where applicable) at 6 and 18 months postpartum; Child health measures, including weight at 6 and 18 months, number of hospitalizations and visits to doctors within the first 6 and 18 months as reported by mother; Mother's mental health outcome (EPDS and GHQ scores) at 18 months postpartum |
|
14 |
Not yet recruiting
|
African American Depression Intervention Trial (AADI)
Condition: |
Major Depressive Disorder |
Intervention: |
Behavioral: Coping with Depression Course (CWD) and Oh Happy Day Class (OHDC) |
Outcome Measures: |
Center for Epidemiologic Studies Depression Scale (CES-D); Quick Inventory of Depressive Symptomatology (QIDS) |
|
15 |
Not yet recruiting
|
A Family-based Primary Care Intervention to Enhance Older Men's Depression Care
Condition: |
Major Depression |
Interventions: |
Behavioral: Family-based Depression intervention; Behavioral: Usual care plus educational materials |
Outcome Measures: |
Depressive symptoms; Medication adherence; Family caregiver satisfaction; Health-related functional disability; Family self-management support |
|
16 |
Unknown †
|
Evaluating the Efficacy of Adjunctive Minocycline for the Treatment of Bipolar Depression
Conditions: |
Bipolar Disorder; Bipolar Depression; Bipolar I Depression; Bipolar II Depression |
Intervention: |
Drug: Minocycline |
Outcome Measures: |
Change from baseline to week 8 on the Montgomery Asberg Depression Rating Scale (MADRS); Change from baseline to week 8 on the Hamilton Depression Rating Scale 17-item (HAMD-17); Change from baseline to week 8 on the Somatic Symptom Inventory (SSI); Change from baseline to week 8 on the Clinical Global Impression (CGI) Rating Scale; Change from baseline to week 8 in the in neurocognitive function; Monitoring of Side-effects from baseline to week 8 with the Toronto Side Effect Scale (TSES); Monitoring of suicide severity from baseline to week 8 with the Columbia Suicide Severity Rating Scale (C-SSRS).; Change from baseline to week 8 in concentrations of pro-and anti-inflammatory cytokines (i.e. TNFα, IL-1β, IL-2, IL-6, IL8, IFNγ, IL-4, IL-5, IL-10) |
|
17 |
Recruiting
|
Phenotype Depression Study
Condition: |
Major Depressive Disorder |
Intervention: |
|
Outcome Measures: |
We are using clinician administered and self report psychiatric measurements to compare relevant symptom domains in patients with major Depression and increased inflammation versus patients with major Depression without increased inflammation.; We are measuring immune markers for the identification of relevant immunologic patterns of activation in patients with major Depression and increased inflammation versus patients with major Depression without increased inflammation. |
|
18 |
Not yet recruiting
|
Evaluation of an Integrated Microfinance and Depression Care Program for Women
Conditions: |
Depression; Anxiety |
Interventions: |
Behavioral: LIFE-DM; Drug: Guideline Antidepressant Care |
Outcome Measures: |
Change in Patient Health Questionnaire-9; Change in MINI Diagnostic Interview; Change in Quality of Life Enjoyment and Satisfaction Questionnaire; Change in Self-Efficacy; Change in Medical Outcome Study (MOS)-Social Support Survey; Change in Medical Outcomes Study (MOS) 12-Item Short Form Health Survey (SF-12); Change in Generalized Anxiety Disorder (GAD-7); Change in Behavior Activation for Depression Scale (BADS); Change in income |
|
19 |
Recruiting
|
Fevarin® Effectiveness in Treatment of Depression in Patients With Neurological Disorder
Condition: |
Depression |
Intervention: |
|
Outcome Measures: |
Prevalence of different neurological disorders associated with Depression treated with fluvoxamine (Fevarin®).; Demographics of patients (age, gender, race, family status, education, employment).; Change in the Hospital Anxiety and Depression Scale (HADS) Depression Subscale Score; Number and proportion of patients with Depression symptoms change measured by Hospital Anxiety and Depression Scale (HADS); Change in the Hospital Anxiety and Depression Scale (HADS) Anxiety Subscale Score; Global severity of illness and change in the clinical condition measured by Clinical Global Impression scale; Number and proportion of patients with change in Clinical Global Impression scale; Anxiety and Depression symptoms score measured by Hospital Anxiety and Depression Scale (HADS); Number and proportion of patients with anxiety symptoms change measured by Hospital Anxiety and Depression Scale (HADS) |
|
20 |
Recruiting
|
Bending Adolescent Depression Trajectories Through Personalized Prevention
Condition: |
Depression |
Interventions: |
Behavioral: Interpersonal Psychotherapy- Adolescent Skills Training; Behavioral: Coping with Stress |
Outcome Measures: |
Presence of a Major Depressive Episode or Dysthymia on the Schedule for Affective Disorders for School Aged Children - Present and Life Time Version (K-SADS-PL); Presence of A Major Depressive Episode or Dysthymia on the Schedule for Affective Disorders for School Aged Children - Present and Life Time Version (K-SADS-PL); Children's Depression Inventory (CDI); Children's Global Assessment Scale (CGAS) |
|