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DIABETES MELLITUS and ACTIQ

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DIABETES MELLITUS Symptoms and Causes

Diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose comes from the foods you eat. Insulin is a hormone that helps the glucose get into your cells to give them energy. With type 1 diabetes, your body does not make insulin. With type 2 diabetes, the more common type, your body does not make or use insulin well. Without enough insulin, the glucose stays in your blood. You can also have prediabetes. This means that your blood sugar is higher than normal but not high enough to be called diabetes. Having prediabetes puts you at a higher risk of getting type 2 diabetes.

Over time, having too much glucose in your blood can cause serious problems. It can damage your eyes, kidneys, and nerves. Diabetes can also cause heart disease, stroke and even the need to remove a limb. Pregnant women can also get diabetes, called gestational diabetes.

Blood tests can show if you have diabetes. One type of test, the A1C, can also check on how you are managing your diabetes. Exercise, weight control and sticking to your meal plan can help control your diabetes. You should also monitor your blood glucose level and take medicine if prescribed.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Check out the latest treatments for DIABETES MELLITUS

DIABETES MELLITUS treatment research studies

ACTIQ clinical trials, surveys and public health registries


Find Drug Side Effect reports



ACTIQ Side Effects

Somnolence (67)
Off Label Use (59)
Dental Caries (55)
Pain (44)
Vomiting (33)
Lethargy (33)
Overdose (30)
Nausea (29)
Death (29)
Tooth Loss (25)
Suicide Attempt (22)
Loss Of Consciousness (20)
Confusional State (20)
Tooth Disorder (19)
Fatigue (18)
Dependence (17)
Coma (16)
Accidental Overdose (16)
Convulsion (16)
Dyspnoea (16)
Incorrect Dose Administered (15)
Depression (14)
Hypotension (14)
Fall (13)
Diarrhoea (13)
Dehydration (13)
Withdrawal Syndrome (12)
Accidental Exposure (12)
Tachycardia (12)
Cardiac Arrest (12)
Weight Decreased (12)
Suicidal Ideation (11)
Hallucination (10)
Dry Mouth (10)
Insomnia (9)
Malignant Neoplasm Progression (9)
Pneumonia (9)
Respiratory Arrest (9)
Miosis (9)
Amnesia (9)
Anxiety (9)
Abnormal Behaviour (9)
Dysarthria (9)
Agitation (9)
Respiratory Depression (8)
Mental Status Changes (8)
Treatment Noncompliance (8)
Hyperhidrosis (8)
Malaise (8)
Tremor (8)

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Abilify (10132)
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Amoxicillin (4387)
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Zyrtec(1669)

Recent Reviews

I received an injection of zostavax in August 2005 and approx 3 months later I was diagnosed with TYPE 1 DIABETES. No one in my entire family history has ever had diabetes. I was and still am 185 lbs.

Hello, I was given Azastin or Avastin for macular edema. I also have retinopathy from diabetes. I was given this shot in my eye in April of this yr. Within 2 days, I had cellulitis in both legs. Horrible pain. Dark red all over from my knees to my

Another thing, can a patient with diabetes type 1 and previously suffered and recovered from Multiple sclerosis ( M-S ) use Spasfon ???

Before I took atenolol i had a perfect glucose numbers after taking it I came down with diabetes. I am 102lbs, 4'11, have always eaten healthy, exercise my whole life. I am 76. I was taken off atenolol after5 years...and NO ONE in my family for ge

Burning sensation, confusion, mental states changes, lethargy, chest pain, pain, communication difficulty.88 years old with astma, high blood pressure, diabetes, prostate enlargement,

Can I take ciprofloxacin with my medicines for diabetes

Can taking of Neuleptil unregularely by father couse a 1st level diabetes for his son?

Dont get discouraged, I am 21 years old and got diagnosed with diabetes when i was 15. I hated it for a little while then i thought well i have to live with it so i better make the best of it. I, just like anyone, wanted to live an ordinary teen life

Good effects on diabetes. weight reduction -rapid and moderate to excessive hair fall after 3 months of use

Hi, I'm 21 years old, recently released from the hospital for possible brain infection (took a variety of antibiotics and anti-virals). I have possible diabetes and I recently developed tinnitus I think, and the possible causes for it is my prolonged

I am 14 and type one diabetic, and i just want it to go away so i can live a normal happy life, i would like to drink to see what its like (typical teen) but i really dont want diabetes , so i don't really care about it, my mum and dad get worried be

DIABETES MELLITUS Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Procedural Pain Treatment With Transmucosal Sublingual Fentanyl Tablet in Colonoscopy Patients
Conditions: Colonoscopy;   Pain
Interventions: Drug: Fentanyl;   Drug: Placebo
Outcome Measures: Efficacy of fentanyl transmucosal tablet to placebo in patients having colonoscopy.;   The safety of fentanyl transmucosal tablet to placebo in patients having colonoscopy.
2 Recruiting Remifentanil vs Fentanyl During Cardiac Surgery and Chronic Thoracic Pain
Conditions: Chronic Pain;   Sternotomy;   Remifentanil;   Fentanyl
Interventions: Drug: Fentanyl;   Drug: Remifentanil
Outcome Measures: Chronic thoracic pain;   Mean Numerical Rating Scale (NRS) score;   Quality of life;   Thermal detection and pain thresholds;   Pain variability;   Use of analgesics during and after hospitalization;   Genetic variances;   Total medical costs and productivity costs during one year, including costs of hospitalization days (ICU and non-ICU) and costs of medications;   Mean pain NRS (Numerical Rating Scale)
3 Not yet recruiting Study to Explore Effectiveness of Sublingual Fentanyl Spray in Emergency Department Patients With Acute Pain
Condition: Acute Pain
Interventions: Drug: Morphine 6 mg;   Drug: Fentanyl 100 µg;   Drug: Fentanyl 200 µg;   Drug: Fentanyl 400 µg;   Drug: Placebo Sublingual Spray;   Drug: Intravenous Placebo
Outcome Measures: Percentage of participants requiring additional doses of randomized pain medication;   Percentage of participants requiring additional doses of randomized pain medication at secondary time points;   Visual analogue scale (VAS) Summed Pain Intensity Difference (SPID) calculated as Area under the Curve (AUC) every 30 minutes;   Number of Investigational Product (IP) administrations;   Time to onset of pain relief (in minutes) using the stopwatch method;   Richmond Agitation Sedation Scale (RASS) score;   Percentage of Participants requiring rescue medication;   Time until rescue medication was required;   Percentage of participants experiencing a treatment-related adverse event;   Percentage of participants with clinically significant changes in vital signs
4 Not yet recruiting Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain
Condition: Labor Pain
Interventions: Drug: Clonidine or Fentanyl;   Drug: Clonidine or fentanyl
Outcome Measures: Pain Score on a VAS scale;   Maternal blood pressure;   Maternal heart rate;   Neonatal Apgar score;   Number of spontaneous vaginal deliveries
5 Unknown  Intranasal Fentanyl for Pain Management
Conditions: Trauma;   Pain
Interventions: Drug: intravenous fentanyl;   Drug: intra-nasal fentanyl
Outcome Measures: The primary measure will be the change recorded in patients subjective pain using a standardized scale;   Change in patients vital signs: blood pressure, respiratory rate, heart rate, pulse oximetry will be monitored at 5 and 10 minutes following Atomized Fentanyl
6 Recruiting Intranasal Fentanyl for Management of Pain Associated With Cystoscopic Procedures
Conditions: Other Acute Pain;   Pain Experienced During Cystoscopy
Intervention: Drug: Fentanyl pectin
Outcome Measures: Change from baseline in pain numeric rating scale;   Oxyhemoglobin saturation
7 Recruiting Safety and Efficacy Study of Fentanyl Buccal Tablet Use in the Emergency Department for Isolated Extremity Injury
Condition: Pain
Interventions: Drug: Fentanyl;   Drug: Oxycodone/acetaminophen;   Drug: oxycodone/acetaminophen
Outcome Measures: Pain Level;   Nausea level;   Occurrence of adverse events
8 Recruiting Fentanyl for Breakthrough Pain in the Emergency Department
Condition: Pain
Interventions: Drug: Fentanyl Nasal Spray;   Drug: Hydromorphone PCA;   Other: Placebo Nasal Spray
Outcome Measure: Total Pain Relief Score
9 Unknown  Epidural Volume Extension and Intrathecal Use of Local Anesthetics in Cesarean Sections
Condition: Stillborn Caesarean Section
Interventions: Drug: Bupivacaine- Fentanyl - Normal Saline;   Drug: Ropivacaine-Fentanyl-Normal Saline;   Drug: Levobupivacaine- Fentanyl- Normal Saline;   Drug: Bupivacaine + Fentanyl;   Drug: Ropivacaine + Fentanyl;   Drug: Levobupivacaine + Fentanyl
Outcome Measures: Dermatomes of Sensory block;   Motor block;   Arterial Blood Pressure
10 Unknown  Safety of Fentanyl TAIFUN Treatment
Condition: Breakthrough Cancer Pain
Interventions: Drug: Fentanyl TAIFUN;   Drug: Opioid
Outcome Measures: AE Profile;   To characterize the safety of Fentanyl TAIFUN treatment vs. the current BTP treatment based on the AE profile;   To estimate the proportion of patients taht can be titrated to an effective dose of Fentanyl TAIFUN;   To evaluate the efficacy of Fentanyl TAIFUN with the titrated dose and the current BTP treatment with the confirmed dose;   To evaluate patients's preference between Fentanyl TAIFUN and the baseline BTP medication;   To evaluate the sustained analgesic effect of Fentanyl TAIFUN and the current BTP treatment
11 Not yet recruiting An Assessment of the Ability of Fentanyl Citrate Nasal Spray to Manage Breakthrough Pain in Cancer Patients.
Condition: Pain
Intervention: Drug: Fentanyl Citrate Nasal Spray (FCNS)
Outcome Measures: Pain Intensity;   Pain Management Satisfaction
12 Not yet recruiting Effectiveness of Intranasal Versus Intravenous Fentanyl in Preterm and Term Newborns for Pain Prevention
Condition: Pain
Intervention: Drug: Fentanyl
Outcome Measure: Pain scale - N-PASS
13 Recruiting Compare Propofol to Fentanyl and Midazolam for Colonoscopy
Conditions: Colon Cancer;   Rectal Cancer;   Colonic Diverticulosis
Interventions: Drug: Fentanyl;   Drug: Propofol;   Drug: Midazolam
Outcome Measures: Patient satisfaction;   Patient discomfort
14 Recruiting Fentanyl Pectin Nasal Spray (FNPS) for Exercise-Induced Breakthrough Dyspnea
Condition: Advanced Cancers
Interventions: Drug: Fentanyl Pectin Nasal Spray;   Drug: Placebo Nasal Spray;   Other: Walk Test;   Behavioral: Questionnaires;   Behavioral: Mental Ability Tests
Outcome Measure: Effect of Prophylactic Fentanyl Pectin Nasal Spray (FPNS)
15 Recruiting Fentanyl in Colonoscopy
Condition: Pain
Interventions: Drug: Routine medication arm;   Drug: Fentanyl on-demand arm
Outcome Measures: Pain;   Additional medication
16 Recruiting The Value of Adding Either Meperdine or Fentanyl to Clonidine-bupivacaine
Condition: Amputation Stumps
Interventions: Drug: Meperdine;   Drug: Fentanyl
Outcome Measures: the hemodynamic effects .;   the analgesic efficacy.
17 Unknown  Subarachnoid Administration of Levobupivacaine for Cesarean Section
Condition: Stillborn Caesarean Section
Interventions: Drug: Bupivacaine plain;   Drug: Ropivacaine plain;   Drug: Levobupivacaine plain;   Drug: bupivacaine plain +fentanyl;   Drug: ropivacaine plain +. fentanyl;   Drug: Levobupivacaine plain +fentanyl
Outcome Measures: Sensory block;   Motor block;   Hemodynamics profile (arterial pressure. heart rate)
18 Recruiting Treatment of Pain in Head-and-Neck Cancer Patients: is Methadone More Effective?
Conditions: Pain;   Cancer of Head and Neck
Interventions: Drug: fentanyl;   Drug: methadone
Outcome Measures: significant pain relief (reduction of Numeric Rating Scale (NRS) of 50%);   time to achieve significant pain relief;   side-effect profile
19 Recruiting Comparison of Propofol-fentanyl and Midazolam-fentanyl for Conscious Sedation
Condition: Emergencies
Interventions: Drug: Propofol;   Drug: Midazolam;   Drug: Fentanyl
Outcome Measures: Recovery time;   Patients' Pain perception
20 Unknown  Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section
Condition: Pain
Interventions: Drug: Preservative free morphine;   Drug: Fentanyl
Outcome Measures: Postsurgical pain;   Nausea