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DIABETES MELLITUS and Plavix

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DIABETES MELLITUS Symptoms and Causes

Diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose comes from the foods you eat. Insulin is a hormone that helps the glucose get into your cells to give them energy. With type 1 diabetes, your body does not make insulin. With type 2 diabetes, the more common type, your body does not make or use insulin well. Without enough insulin, the glucose stays in your blood. You can also have prediabetes. This means that your blood sugar is higher than normal but not high enough to be called diabetes. Having prediabetes puts you at a higher risk of getting type 2 diabetes.

Over time, having too much glucose in your blood can cause serious problems. It can damage your eyes, kidneys, and nerves. Diabetes can also cause heart disease, stroke and even the need to remove a limb. Pregnant women can also get diabetes, called gestational diabetes.

Blood tests can show if you have diabetes. One type of test, the A1C, can also check on how you are managing your diabetes. Exercise, weight control and sticking to your meal plan can help control your diabetes. You should also monitor your blood glucose level and take medicine if prescribed.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Check out the latest treatments for DIABETES MELLITUS

DIABETES MELLITUS treatment research studies

Plavix clinical trials, surveys and public health registries


Find Drug Side Effect reports



Plavix Side Effects

Myocardial Infarction (302)
Dyspnoea (270)
Anaemia (263)
Contusion (260)
Asthenia (251)
Death (238)
Cerebrovascular Accident (215)
Gastrointestinal Haemorrhage (207)
Dizziness (204)
Chest Pain (200)
Haemorrhage (176)
Fall (166)
Fatigue (162)
Headache (152)
Haemoglobin Decreased (145)
Diarrhoea (137)
Nausea (132)
Epistaxis (132)
Pruritus (129)
Coronary Artery Occlusion (123)
Pain (117)
Pyrexia (116)
Malaise (112)
Loss Of Consciousness (109)
Rash (108)
Rectal Haemorrhage (106)
Pain In Extremity (105)
Transient Ischaemic Attack (104)
Off Label Use (100)
Weight Decreased (98)
Atrial Fibrillation (98)
Melaena (96)
Arthralgia (93)
International Normalised Ratio Increased (91)
Haematemesis (90)
Abdominal Pain Upper (90)
Pneumonia (89)
Condition Aggravated (89)
Cardiac Failure Congestive (87)
Oedema Peripheral (87)
Renal Failure (85)
Vomiting (85)
Hypertension (85)
Angina Pectoris (85)
Hypotension (84)
Back Pain (83)
Confusional State (81)
Thrombosis (81)
Gait Disturbance (73)
Myalgia (72)

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Common Meds

Abilify (10132)
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Mirena (41254)
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Wellbutrin (6324)
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Zoloft(6792)
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Recent Reviews

75 mg

A horrible experience taking plavix, i had all the side effects taking this drug ,question ur Dc. before taking it and 9don,t believe him)

About a year ago i had a stroke also bad dry skin,i also had a full head of hair and a full beard lately my beard and hair are both are both falling out

Could plavix be the reason for my hair loss

Deadly stay away

Gastrointestinal. Severe pain starting in middle of chest and wrapping around to middle of back. Tests showed inflamation in stomach and I am now on a bland diet indefinately. Also had trouble swallowing pills and food.&

I AM HAVING HAIR LOSS AND I AM NOT TAKING PLAVIX

I have been on plavix and asparin 4 months, SP cerebral aneurysm repair) this evening I fell hard on my low back(completely missed a chair ), i couldnt move for a few mins, really hurt... got up, applied ice to low back,moving ok but sore, I guess I

I received an injection of zostavax in August 2005 and approx 3 months later I was diagnosed with TYPE 1 DIABETES. No one in my entire family history has ever had diabetes. I was and still am 185 lbs.

I was placed on plavix after a pfo closure surgery. I have felt depressed and have experienced crying spells. Its very unlike my personality. The more people I talk to the more common it seems to be a serious issue.

Hello, I was given Azastin or Avastin for macular edema. I also have retinopathy from diabetes. I was given this shot in my eye in April of this yr. Within 2 days, I had cellulitis in both legs. Horrible pain. Dark red all over from my knees to my

Another thing, can a patient with diabetes type 1 and previously suffered and recovered from Multiple sclerosis ( M-S ) use Spasfon ???

Before I took atenolol i had a perfect glucose numbers after taking it I came down with diabetes. I am 102lbs, 4'11, have always eaten healthy, exercise my whole life. I am 76. I was taken off atenolol after5 years...and NO ONE in my family for ge

Burning sensation, confusion, mental states changes, lethargy, chest pain, pain, communication difficulty.88 years old with astma, high blood pressure, diabetes, prostate enlargement,

Can I take ciprofloxacin with my medicines for diabetes

Can taking of Neuleptil unregularely by father couse a 1st level diabetes for his son?

Dont get discouraged, I am 21 years old and got diagnosed with diabetes when i was 15. I hated it for a little while then i thought well i have to live with it so i better make the best of it. I, just like anyone, wanted to live an ordinary teen life

Good effects on diabetes. weight reduction -rapid and moderate to excessive hair fall after 3 months of use

Hi, I'm 21 years old, recently released from the hospital for possible brain infection (took a variety of antibiotics and anti-virals). I have possible diabetes and I recently developed tinnitus I think, and the possible causes for it is my prolonged

I am 14 and type one diabetic, and i just want it to go away so i can live a normal happy life, i would like to drink to see what its like (typical teen) but i really dont want diabetes , so i don't really care about it, my mum and dad get worried be

DIABETES MELLITUS Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting Genotyping Guided Individualized Treatment of Clopidogrel and Ticagrelor in ACS
Condition: CLOPIDOGREL, POOR METABOLISM of (Disorder)
Interventions: Drug: genotyping guided therapy Ticagrelor, Clopidogrel;   Drug: standard therapy clopidogrel
Outcome Measure: Clopidogrel response status as measured by the LTA assay in CYP2C19*2 carriers.
2 Recruiting Comparative Pharmacodynamics and Pharmacokinetics Study of Generic and Reference Clopidogrel Products
Condition: Antiplatelet Agents
Interventions: Drug: Generic clopidogrel product Apolets®;   Drug: Original clopidogrel product Plavix®
Outcome Measures: Pharmacodynamic effect: The platelet inhibition effect of clopidogrel at the various times on day 7 (0-24 hours) (at steady state);   Pharmacokinetic profiles: Area Under the Concentration-Time Curve (AUC 0-24);   Pharmacokinetic profiles: The Maximum Plasma Concentration (Cmax);   Pharmacokinetic profiles: Time to Maximum Plasma Concentration (Tmax)
3 Recruiting Ramipril and Clopidogrel in Oxidative Stress, Vascular Inflammation and Endothelial Dysfunction in Type 2 Diabetes and Diabetic Nephropathy
Conditions: Diabetes Type 2;   Diabetic Nephropathy;   Vascular Disease
Interventions: Drug: Ramipril;   Drug: Clopidogrel
Outcome Measures: Changes in Asymmetric dimethylarginine (ADMA) blood levels after the combined treatment with ramipril and clopidogrel compared with ramipril monotherapy;   Changes in High-sensitivity C-reactive protein (HsCRP) blood levels after the combined treatment with ramipril and clopidogrel compared with ramipril monotherapy;   Changes in soluble CD40 Ligand (sCD40L)blood levels after the combined treatment with ramipril and clopidogrel compared with ramipril monotherapy;   Changes in urine 8-isoprostane-F2 levels after the combined treatment with ramipril and clopidogrel compared with ramipril monotherapy;   Reduction in albumine to creatine ratio after the combined treatment with ramipril and clopidogrel compared with ramipril monotherapy;   Changes in ADMA blood levels after treatment with ramipril;   Increase of Glomerular Filtration Rate (GFR) after combined treatment with ramipril and clopidogrel and after ramipril monotherapy;   Change from baseline in carotid intima-media thickness after combined therapy with ramipril and clopidogrel and after ramipril monotherapy
4 Recruiting Aspirin and Plavix Following Coronary Artery Bypass Grafting
Condition: Coronary Graft Patency
Interventions: Drug: clopidogrel;   Drug: sugar pill
Outcome Measures: Incidence of more than 50% stenosis in graft with combination therapy with aspirin and clopidogrel vs. aspirin alone;   Incidence of bleeding between the two treatment arms;   Percent change major adverse cardiovascular events (angina, any thrombotic events, and myocardial infarction) with combination therapy with aspirin and clopidogrel vs. aspirin alone
5 Not yet recruiting Optimal Anti-platelet Treatment for Patients With Clopidogrel Low Response
Condition: Coronary Artery Disease
Interventions: Drug: Ticagrelor;   Drug: Clopidogrel;   Drug: Cilostazol
Outcome Measures: Inhibition of platelet aggregation (IPA);   Clinical efficacy
6 Recruiting Effectiveness of Clopidogrel Resinate in PCI(PRIDE)
Condition: Coronary Artery Disease
Interventions: Drug: Pregrel®;   Drug: Plavix®
Outcome Measures: composite of death (all cause-mortality), MI (Q wave and non Q wave) and stroke;   composite of death, MI, stroke, or urgent revascularization;   Individual components of death, MI, stroke, or urgent revascularization;   The need for target vessel revascularization or any revascularization;   The incidence of early discontinuation of study drugs;   The incidence of major bleeding events;   Stent thrombosis
7 Not yet recruiting Clopidogrel Resistance and Embolism in Carotid Artery Stenting
Condition: Carotid Stenosis
Interventions: Drug: Ticlopidine + Ginko biloba;   Drug: Clopidogrel
Outcome Measures: New ischemic lesion on diffusion-weighted imaging (DWI);   Number and Volume of new ischemic lesions on DWI;   Benign and malignant microembolic signals (MES) on transcranial Doppler (TCD);   Ischemic stroke or transient ischemic attack (TIA);   Change of clopidogrel resistance;   Pucture site hematoma;   Mycocardial infarction;   Death;   Hematological abnormalities
8 Recruiting Reloading Prasugrel or Clopidogrel on High Platelet Reactivity Before Percutaneous Coronary Intervention
Condition: Acute Coronary Syndrome
Interventions: Drug: Prasugrel;   Drug: Clopidogrel
Outcome Measures: HPR at 24 hours;   MACE;   Bleeding;   HPRs
9 Recruiting Does Continued Use of Clopidogrel Into Surgery Cause Increased Perioperative Bleeding?
Condition: Clopidogrel
Interventions: Drug: Clopidogrel;   Drug: Discontinue Clopidogrel
Outcome Measures: Perioperative Bleeding Complications;   Development of myocardial infarction or thrombosis
10 Unknown  Thromboelastography As An Assessment Tool for Possible Clopidogrel and Aspirin Resistance
Condition: Acute ST SEgment Elevation Myocardial Infarction
Interventions: Drug: Aspirin (200mg) and/or Plavix (150mg) dosage according to TEG;   Drug: Aspirin 100mg and Plavix 75mg
Outcome Measures: To determine usefulness of thromboelastography (TEG) as a valuable tool in assessing platelet response to clopidogrel treatment and post-treatment platelet reactivity during acute ST segment elevation myocardial infarction (STEMI).;   To determine the correlation between platelet response to clopidogrel treatment and the outcome of patients who underwent percutaneous coronary intervention (PCI) for STEMI.
11 Recruiting Antiplatelet Effects of Ticagrelor Versus Clopidogrel in American Indian Patients
Condition: Coronary Artery Disease
Interventions: Drug: Ticagrelor;   Drug: Clopidogrel
Outcome Measures: Compare ticagrelor's versus clopidogrel's inhibition of the P2Y12 receptor as measured by the decrease in P2Y12 Reaction Units (PRU) using VerifyNow TM.;   Compare the decrease of P2Y12 Reaction Units (PRU) by VerifyNow TM from ticagrelor and clopidogrel.;   Compare the decrease in P2Y l2 Reaction Units (PRU) by VerifyNow™ from ticagrelor's and clopidogrel's morning dose on Day 7;   To evaluate and compare the pharmacodynamic effects, measured by the vasodilator-stimulated phosphoprotein (VASP) assay (platelet reactivity index [PRI]), in all subjects;   Assess and to compare the percentage of subjects with High on-treatment Platelet Reactivity (HPR) at all time points after randomized study treatment.
12 Recruiting Evaluation of the Biological Response to Clopidogrel in Patients With Ischemic Stroke
Conditions: Brain Ischemia;   Ischemic Attack
Intervention: Drug: Clopidogrel
Outcome Measures: adrenergic component of the platelet response;   VASP-CMF;   ELISA VASP;   active metabolite of clopidogrel;   Genotyping of MDR-1 and P450 2C19
13 Recruiting Transition From Ticagrelor to Clopidogrel Following Acute Coronary Syndrome: To Bolus or Not?
Condition: Acute Coronary Syndrome
Intervention: Drug: Clopidogrel
Outcome Measures: Platelet inhibition as assessed by P2Y12 reaction Unit (PRU) after transition from Ticagrelor to Clopidogrel.;   The difference in platelet inhibition (as expresses as PRU) between the two groups at specified time points.
14 Recruiting Uninterrupted Clopidogrel Therapy Before Elective Colonoscopy Will Increase the Risk of Post-polypectomy Bleeding
Condition: Gastrointestinal Bleeding
Intervention: Drug: clopidogrel
Outcome Measures: Delayed post-polypectomy bleeding;   Immediate post-polypectomy bleeding
15 Not yet recruiting Comparing Ticagrelor and Clopidogrel Pharmacodynamics After Thrombolysis
Conditions: Acute ST Segment Elevation Myocardial Infarction;   Acute Coronary Syndrome
Interventions: Drug: Ticagrelor;   Drug: Clopidogrel
Outcome Measures: Pharmacodynamics (PRU and IPA) of ticagrelor vs Clopidogrel using VASP and VerifyNow;   Pharmacokinetic (AUC, Cmax, Tmax)
16 Unknown  Plavix, Prasugrel and Drug Eluting Stents Pilot Trial
Conditions: Coronary Artery Disease;   Platelet Aggregation Inhibitors;   PCI- Percutaneous Coronary Intervention
Interventions: Drug: Loading Dose Arm;   Drug: Maintenance Dose Arm
Outcome Measures: Change in platelet reactivity after switching medication regimen of two thienopyridines- clopidogrel and prasugrel;   Occurrence of all bleeding events for subjects enrolled into the trial;   Occurrence of all MACE events for subjects enrolled into the trial
17 Unknown  Clopidogrel Reloading in Patients With NSTEACS Undergoing Percutaneous Coronary Intervention on Chronic Clopidogrel Therapy
Conditions: Acute Coronary Syndrome;   Myocardial Infarction
Interventions: Drug: Clopidogrel;   Drug: Placebo
Outcome Measures: Major Adverse Cardiovascular Events;   Bleeding Events;   Grade of platelet residual reactivity
18 Not yet recruiting Effect of Modifying Anti-platelet Treatment to Ticagrelor in Patients With Diabetes and Low Response to Clopidogrel
Conditions: Diabetes Mellitus;   Coronary Disease
Interventions: Drug: Ticagrelor;   Drug: Continued clopidogrel
Outcome Measures: Rate of elevation of troponin or CK-MB (above the upper limit of normal, and above 3 times the upper limit of normal) measured 20-24 hours after the PCI.;   Rate of major adverse cardiovascular endpoints including death, myocardial infarction or urgent target vessel revascularization at 30 days
19 Recruiting Ticagrelor Versus Clopidogrel in Type 2 Diabetic Patients
Conditions: Type-2 Diabetes Mellitus;   Coronary Artery Disease
Interventions: Drug: Ticagrelor + Aspirin;   Drug: Clopidogrel + Aspirin
Outcome Measures: Thrombus formation;   Platelet reactivity;   Vasodilator-Stimulated Phosphoprotein phosphorylation assay
20 Unknown  Pharmacogenomics and Effective Treatment With Clopidogrel
Condition: Pharmacogenomics
Intervention: Genetic: Pharmacogenomics
Outcome Measure: