Rank |
Status |
Study |
1 |
Recruiting
|
Blinded, Randomized Study of Gabapentin (Neurontin®) and Gabapentin Enacarbil (Horizant™) in Restless Leg Syndrome
Condition: |
Restless Leg Syndrome |
Interventions: |
Drug: Gabapentin immediate release (Neurontin); Drug: Gabapentin enacarbil extended release (Horizant) |
Outcome Measures: |
International Restless Leg Syndrome Rating Scale (IRLS); Restless Leg Syndrome Quality of Life Scale (RLSQoL) |
|
2 |
Not yet recruiting
|
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
Condition: |
Pain, Postoperative |
Interventions: |
Drug: Gabapentin; Drug: Simple Syrup |
Outcome Measures: |
Difference in pain control when adding Gabapentin to a multimodal pain management protocol in pediatric post-operative posterior spinal fusion patients.; Determine if opiate usage is less in the Gabapentin group versus control. |
|
3 |
Recruiting
|
Effectiveness of Gabapentin on Chronic Irritability in Neurologically Impaired Children
Conditions: |
Neurologically Impaired; Irritable Mood; Signs and Symptoms, Digestive; Sleeplessness; Chronic Pain |
Interventions: |
Drug: Gabapentin; Drug: placebo |
Outcome Measures: |
Symptom relief for chronic irritability in neurologically impaired children using Gabapentin.; Prevalence of associated gastrointestinal and sleep problems in neurologically impaired children and improvement using Gabapentin. |
|
4 |
Recruiting
|
The Effect of Gabapentin on Thoracic Epidural Analgesia Following Thoracotomy
Condition: |
Pain, Postoperative |
Interventions: |
Drug: Gabapentin; Drug: Placebo |
Outcome Measures: |
Persistent post surgical pain; Acute postoperative pain; Usage of epidural infusion of local and opioid analgesics (ml); Early postoperative pain; Consumption of opioid analgesics; Time to first request for additional analgesics; Analgesia related side-effects; Convalescence of gastrointestinal function; Health related quality of life; Patient satisfaction; Intensity of preoperative anxiety; Convalescence of lung function (spirometry); Sleep quality; Walking distance (meters); Fatigue; Hospital length of stay (days); Use of a vasopressor agent to correct hypotension |
|
5 |
Recruiting
|
Postoperative Tramadol/Gabapentin/Acetaminophen Versus Tramadol/Placebo/Acetaminophen
Condition: |
Pain |
Interventions: |
Drug: Gabapentin; Drug: Tramadol; Drug: Ibuprofen |
Outcome Measures: |
Efficacy of scheduled tramadol + PRN ibuprofen vs. scheduled tramadol + scheduled Gabapentin + PRN ibuprofen; Side effects of scheduled tramadol + PRN ibuprofen vs. scheduled tramadol + scheduled Gabapentin + PRN ibuprofen |
|
6 |
Recruiting
|
Does a Perioperative Course of Gabapentin Improve Analgesia After Cesarean Delivery?
Condition: |
Pain |
Interventions: |
Drug: Gabapentin; Drug: lactose |
Outcome Measures: |
VAS score (VAS 0-100 mm) for maternal pain on movement at 24 hours after surgical incision.; VAS score on movement at 48 hours after surgical incision; VAS scores at rest at 24 and 48 hours after surgical incision; Maternal satisfaction scores at 24 and 48 hours after surgical incision.; Opioid use in the first 48 hours after surgical incision; Time to first analgesic; Sedation; Neonatal apgar scores; Breastfeeding issues; NICU admission |
|
7 |
Recruiting
|
Quality of Life Study Using Gabapentin Versus Venlafaxine in Treating Hot Flashes in Patients With Prostate Cancer
Condition: |
Hot Flashes in Men With Prostate Cancer Receiving Androgen Ablation Therapy |
Interventions: |
Drug: Gabapentin; Drug: Venlafaxine |
Outcome Measures: |
Changes in quality of life; compare toxicity rates between the Gabapentin and venlafaxine treatment groups; Assess changes in the hot flash scores for the two arms; Assess changes in quality of life using the Hot flash related Daily Interference Scale (HFRDIS) |
|
8 |
Recruiting
|
Gabapentin for Insomnia Symptoms and Nighttime Vasomotor Symptoms in Peri- and Postmenopausal Women
Conditions: |
Menopause; Hot Flashes; Vasomotor Disturbance |
Intervention: |
Drug: Gabapentin |
Outcome Measures: |
Tolerability of Gabapentin; VMS frequency, severity, and bothersomeness; Subjective sleep quality; Anxiety; Depressed mood |
|
9 |
Recruiting
|
A Trial of Gabapentin in Vulvodynia: Biological Correlates of Response
Condition: |
Vulvodynia |
Intervention: |
Drug: Gabapentin extended-release |
Outcome Measures: |
The primary outcome measure of this project are to test the prediction that pain from tampon insertion is lower in PVD patients when treated with Gabapentin compared to when treated with placebo.; The secondary outcome measure is to perform a mechanism-based analysis of Gabapentin effectiveness, and to gain insight into the underlying pathophysiology of subtypes of PVD that may lead to more specific treatment options. |
|
10 |
Recruiting
|
Clinical Trial of Gabapentin to Improve Postoperative Pain in Surgical Patients
Condition: |
Postoperative Pain |
Intervention: |
Drug: Gabapentin |
Outcome Measures: |
Postoperative delirium and cognitive decline; Postoperative opioid doses and pain scores |
|
11 |
Unknown †
|
Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy
Condition: |
Postoperative Pain |
Interventions: |
Drug: Gabapentin; Drug: pregabalin |
Outcome Measure: |
Decreased overall pain score as measured by the visual analogue scale |
|
12 |
Recruiting
|
Safety and Efficacy of Gabapentin for Neuropathic Pain in Fabry Disease
Conditions: |
Fabry Disease; Neuropathic Pain |
Interventions: |
Drug: Gabapentin; Drug: placebo |
Outcome Measures: |
average reduction in hydrocodone-acetaminophen use; Number and type of adverse events; Pain levels; Define therapeutic level for Gabapentin |
|
13 |
Unknown †
|
Gabapentin in Functional Dyspepsia Refractory to Proton Pump Inhibition
Condition: |
Functional Dyspepsia |
Interventions: |
Drug: Gabapentin; Drug: Placebo |
Outcome Measures: |
The primary outcome will be the adequacy of symptom control during the last week of the study.; Secondary outcomes equate dyspepsia symptoms with quality of life. The Nepean Dyspepsia Index scores patients on five categories while the Global Overall Symptom Scale measures the severity of dyspepsia on a 1-7 scale. |
|
14 |
Recruiting
|
Efficacy and Safety of Gabapentin in Treating Overactive Bladder
Conditions: |
Urinary Frequency; Urinary Urgency; Nocturia; Incontinence; Detrusor Uninhibited Activity; Quality of Life |
Interventions: |
Drug: Gabapentin; Drug: Solifenacin Succinate; Drug: Placebo drugs |
Outcome Measures: |
improvement of symptom domain means decreased frequency to less than 8 micturitions per 24 hours, no urgency noted per 24 hrs and less that 3 wakening at bedtime for micturation.; Improvement of bladder function domain means increased bladder capacity and decreased overactive detrusor as recorded in urodynamic study.; Improvement in quality of life domain means increased overall quality of life as perceived and result in OAB-q |
|
15 |
Not yet recruiting
|
Effect of Gabapentin on Pain of the Second Cataract Surgery
Condition: |
Hyperalgesia |
Interventions: |
Drug: Gabapentin; Drug: placebo |
Outcome Measures: |
proportion of subjects who answer that "pain was greater" in the second eye surgery; perioperative pain |
|
16 |
Recruiting
|
Preoperative Gabapentin for Post-tonsillectomy Pain in Children
Condition: |
Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy |
Interventions: |
Drug: Gabapentin; Drug: liquid placebo |
Outcome Measures: |
Total oral analgesia consumption; Self-report pain score |
|
17 |
Recruiting
|
Gabapentin Treatment of Cannabis Dependence
Conditions: |
Cannabis Dependence; Cannabis Withdrawal; Cognitive Deficits |
Interventions: |
Drug: Gabapentin 1200mg/day; Drug: Placebo |
Outcome Measure: |
Cannabis Use |
|
18 |
Recruiting
|
Steroids Versus Gabapentin
Conditions: |
Sciatica; Radiculopathy |
Interventions: |
Procedure: epidural steroid injection; Procedure: Sham epidural steroid injection; Drug: Gabapentin; Drug: Placebo Gabapentin |
Outcome Measures: |
leg pain; Back pain; Oswestry disability index; satisfaction |
|
19 |
Recruiting
|
GRASSP: Gralise® for Spine Surgery Pain
Condition: |
Post-laminectomy Pain Syndrome |
Interventions: |
Drug: Gralise®; Drug: Placebo |
Outcome Measures: |
Numeric Rating Scale (NRS); Visual Analog Scale (VAS); Patient Global Assessment (PGA); McGill Pain Questionnaire-2 (MPQ-2); Modified Brief Pain Inventory- short form (mBPI-sf); Insomnia Severity Index (ISI) |
|
20 |
Recruiting
|
Maintenance Gabapentin to Prolong Pregnancy.
Condition: |
Preterm Labor, Premature Birth |
Intervention: |
Drug: Gabapentin |
Outcome Measure: |
Rate of premature birth (before 37 weeks gestation) |
|