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DRUG WITHDRAWAL SYNDROME and Cyclobenzaprine

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DRUG WITHDRAWAL SYNDROME Symptoms and Causes

Opioids, sometimes called narcotics, are a type of drug. They include strong prescription pain relievers, such as oxycodone, hydrocodone, fentanyl, and tramadol. The illegal drug heroin is also an opioid. Some opioids are made from the opium plant, and others are synthetic (man-made).

A doctor may give you a prescription opioid to reduce pain after you have had a major injury or surgery. You may get them if you have severe pain from health conditions like cancer. Some doctors prescribe them for chronic pain.

Opioids can cause side effects such as drowsiness, mental fog, nausea, and constipation. They may also cause slowed breathing, which can lead to overdose deaths. If someone has signs of an overdose, call 9-1-1:

  • The person's face is extremely pale and/or feels clammy to the touch
  • Their body goes limp
  • Their fingernails or lips have a purple or blue color
  • They start vomiting or making gurgling noises
  • They cannot be awakened or are unable to speak
  • Their breathing or heartbeat slows or stops

Other risks of using prescription opioids include dependence and addiction. Dependence means feeling withdrawal symptoms when not taking the drug. Addiction is a chronic brain disease that causes a person to compulsively seek out drugs, even though they cause harm. The risks of dependence and addiction are higher if you abuse the medicines. Abuse can include taking too much medicine, taking someone else's medicine, taking it in a different way than you are supposed to, or taking the medicine to get high.

Opioid abuse, addiction, and overdoses are serious public health problems in the United States. Another problem is that more women are abusing opioids during pregnancy. This can lead to babies being addicted and going through withdrawal, known as neonatal abstinence syndrome (NAS). Opioid abuse may sometimes also lead to heroin use, because some people switch from prescription opioids to heroin.

The main treatment for prescription opioid addiction is medication-assisted treatment (MAT). It includes medicines, counseling, and support from family and friends. MAT can help you stop using the drug, get through withdrawal, and cope with cravings. There is also a medicine called naloxone which can reverse the effects of an opioid overdose and prevent death, if it is given in time.

To prevent problems with prescription opioids, be sure to follow your doctor's instructions when taking them. Do not share your medicines with anyone else. Contact your doctor if you have any concerns about taking the medicines.

NIH: National Institute on Drug Abuse

Check out the latest treatments for DRUG WITHDRAWAL SYNDROME

DRUG WITHDRAWAL SYNDROME treatment research studies

Cyclobenzaprine clinical trials, surveys and public health registries


Find Drug Side Effect reports



Cyclobenzaprine Side Effects

Completed Suicide (160)
Toxicity To Various Agents (127)
Cardiac Arrest (64)
Respiratory Arrest (59)
Overdose (36)
Pain (28)
Cardio-respiratory Arrest (24)
Dizziness (24)
Confusional State (23)
Death (21)
Exposure Via Ingestion (20)
Nausea (18)
Fall (16)
Depression (15)
Convulsion (15)
Constipation (15)
Anxiety (14)
Hallucination (14)
Hypotension (14)
Headache (14)
Vomiting (13)
Fatigue (13)
Dry Mouth (12)
Chest Pain (12)
Deep Vein Thrombosis (12)
Dyspnoea (12)
Loss Of Consciousness (12)
Pulmonary Embolism (12)
Asthenia (11)
Heart Rate Increased (11)
Insomnia (11)
Somnolence (11)
Myoclonus (11)
Delirium (10)
Aspartate Aminotransferase Increased (10)
Coma (10)
Diarrhoea (10)
Intentional Overdose (10)
Hypoaesthesia (10)
Back Pain (9)
Alanine Aminotransferase Increased (9)
Depressed Level Of Consciousness (9)
Gait Disturbance (9)
Tachycardia (9)
Serotonin Syndrome (9)
Hepatic Function Abnormal (8)
Injury (8)
Tremor (8)
Psychotic Disorder (8)
Mental Status Changes (8)

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Recent Reviews

Confusion, ringing of ears, dry (stinging) eyes, nightmares, depression associated with hyper-sensitivity/over-reaction in social events.

Im 16 yrs old and i have a bad lower back and neck so i take cylobenzapr and one time i fell asleep and awoke and was talking but not making no sense

Chantix caused me to haveseizures I would not recommend anyone to take this drug find a different way to quit smoking that is safe.

I HAD 1 SHOT OF THIS AND WITHIN 12 HOURS I WENT FROM A VERY NORMAL BLOOD PRESSURE TO WAKING AT 5 A.M. NEXT DAY WITH 198/110 AND 104 PULSE RATE. IT HAS CONTINUED ALL WEEK AFTER AND I'M NOW ON A BLOOD PRESSURE DRUG TO TRY AND CONTROL IT. EVEN WITH DR

can advagraf makke you look like you are pregnant? Can this drug affect your eye site--blurry vision

Does anyone else have insomnia problems, with this drug, was fine before taking it, but now having major trouble getting to sleep and staying asleep.

I have experienced panic attacks, light headedness and pasty mouth taking this drug at 400mg's.

I have sjogren's syndrome. Can i use arcalion or is it not good for me?

Impact of this drug on blood pressure. Should I be worried?

My symptoms were tired, weak, unable to sleep. Was prescribed half of a 15 MG Mirtazapine nightly to help me sleep. Has this drug been successful used as a sleeping aid?

WHAT ARE SIDE EFFECT OF COTRIMOXAXOLE DRUG

<!--StartFragment--> I have advanced Rheumatoid Arthritis. My Left wrist swelled painfully. Had a negative X-ray so Dr (fully informed for current drug regimens and allergies--Aspirin, Penicillin, Thoradamides, Ornate, Iodine, Latex)

DRUG WITHDRAWAL SYNDROME Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Cyclobenzaprine Extended Release (ER) for Fibromyalgia
Conditions: Fibromyalgia;   Pain;   Sleep;   Fatigue
Interventions: Drug: Cyclobenzaprine ER (AMRIX);   Drug: placebo
Outcome Measures: Visual Analogue Pain Scale;   Brief Fatigue Inventory;   Analogue sleep/wakefulness scale;   Fibromyalgia Impact Questionnaire;   Sheehan Disability SCale;   Quick Inventory of Depression;   Reported Adverse Effects
2 Recruiting Efficacy and Safety of Cyclobenzaprine Hydrochloride Extended Release for the Treatment of Chronic Migraine
Condition: Chronic Migraine
Interventions: Drug: Cyclobenzaprine hydrochloride;   Drug: placebo
Outcome Measures: Mean total number of migraine/migrainous headache days per month;   Mean total number of headache days/month;   mean peak daily and mean average daily pain intensity ratings/month;   mean total number of abortive treatment days/month
3 Recruiting Use of Cyclobenzaprine After Vaginal Surgery
Condition: Postoperative Pain
Intervention: Drug: Cyclobenzaprine
Outcome Measures: Faces Pain scale;   Quantity of pain medications;   Constipation scale
4 Unknown  Study Comparing A New Drug Containing The Combination Meloxicam And Cyclobenzaprine In The Treatment Of Acute Lumbago
Condition: Acute Lumbago
Interventions: Drug: meloxicam/Cyclobenzaprine hydrochloride;   Drug: meloxicam - Movatec®;   Drug: Cyclobenzaprine - Miosan®
Outcome Measures: Pain Reduction;   Frequency of rescue medication use
5 Unknown  A Comparative Study Between Lysine Clonixinate+Cyclobenzaprine and Caffeine+Carisoprodol+Sodium Diclofenac+Paracetamol
Condition: Low Back Pain
Interventions: Drug: Tandrilax;   Drug: Dolamin Flex
Outcome Measures: Pain average reduction;   Identification of possible gastrointestinal effects
6 Recruiting A Randomized Study of Three Medication Regimens for Acute Low Back Pain
Condition: Acute Low Back Pain
Interventions: Drug: Naproxen;   Drug: Cyclobenzaprine;   Drug: Oxycodone/ acetaminophen
Outcome Measure: Roland Morris low back pain functional disability scale