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DRUG WITHDRAWAL SYNDROME and Loratadine

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DRUG WITHDRAWAL SYNDROME Symptoms and Causes

Opioids, sometimes called narcotics, are a type of drug. They include strong prescription pain relievers, such as oxycodone, hydrocodone, fentanyl, and tramadol. The illegal drug heroin is also an opioid. Some opioids are made from the opium plant, and others are synthetic (man-made).

A doctor may give you a prescription opioid to reduce pain after you have had a major injury or surgery. You may get them if you have severe pain from health conditions like cancer. Some doctors prescribe them for chronic pain.

Opioids can cause side effects such as drowsiness, mental fog, nausea, and constipation. They may also cause slowed breathing, which can lead to overdose deaths. If someone has signs of an overdose, call 9-1-1:

  • The person's face is extremely pale and/or feels clammy to the touch
  • Their body goes limp
  • Their fingernails or lips have a purple or blue color
  • They start vomiting or making gurgling noises
  • They cannot be awakened or are unable to speak
  • Their breathing or heartbeat slows or stops

Other risks of using prescription opioids include dependence and addiction. Dependence means feeling withdrawal symptoms when not taking the drug. Addiction is a chronic brain disease that causes a person to compulsively seek out drugs, even though they cause harm. The risks of dependence and addiction are higher if you abuse the medicines. Abuse can include taking too much medicine, taking someone else's medicine, taking it in a different way than you are supposed to, or taking the medicine to get high.

Opioid abuse, addiction, and overdoses are serious public health problems in the United States. Another problem is that more women are abusing opioids during pregnancy. This can lead to babies being addicted and going through withdrawal, known as neonatal abstinence syndrome (NAS). Opioid abuse may sometimes also lead to heroin use, because some people switch from prescription opioids to heroin.

The main treatment for prescription opioid addiction is medication-assisted treatment (MAT). It includes medicines, counseling, and support from family and friends. MAT can help you stop using the drug, get through withdrawal, and cope with cravings. There is also a medicine called naloxone which can reverse the effects of an opioid overdose and prevent death, if it is given in time.

To prevent problems with prescription opioids, be sure to follow your doctor's instructions when taking them. Do not share your medicines with anyone else. Contact your doctor if you have any concerns about taking the medicines.

NIH: National Institute on Drug Abuse

Check out the latest treatments for DRUG WITHDRAWAL SYNDROME

DRUG WITHDRAWAL SYNDROME treatment research studies

Loratadine clinical trials, surveys and public health registries


Find Drug Side Effect reports



Loratadine Side Effects

Dizziness (40)
Accidental Overdose (37)
Convulsion (37)
Dyspnoea (34)
Somnolence (31)
Headache (28)
Malaise (23)
Nausea (23)
Vomiting (23)
Hypersensitivity (23)
Urticaria (21)
Pain (21)
Pruritus (20)
Loss Of Consciousness (20)
Insomnia (19)
Death (19)
Syncope (19)
Palpitations (19)
Swelling Face (17)
Anxiety (17)
Blood Pressure Increased (16)
Abdominal Pain Upper (15)
Completed Suicide (15)
Rash (14)
Overdose (14)
Depression (14)
Asthenia (13)
Burning Sensation (13)
Fall (13)
Pyrexia (13)
Cholestasis (12)
Cardiac Arrest (12)
Condition Aggravated (12)
Diarrhoea (12)
Vision Blurred (12)
Confusional State (12)
Cough (12)
Abortion Spontaneous (11)
Cerebrovascular Accident (11)
Torsade De Pointes (11)
Feeling Abnormal (11)
Heart Rate Increased (11)
Muscle Spasms (10)
Ventricular Tachycardia (10)
Hyperhidrosis (10)
Agitation (9)
Angioedema (9)
Autoimmune Hepatitis (9)
Chest Pain (9)
Arrhythmia (9)

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Recent Reviews

one 10 mg pill cuased presure in thechest bad muslespasms in the back think past doses has sent me skizzo

Alopecia areata........ anyone else?

Can my one year old take loratadine

Can this medicine cause you to have a very fast heart rate?

Can you take tylenol right after taking a loratadine?

How long should a child of 5 years of age be on Loratadine (liquid form) and will this effect her alertness in school?

I was taking the loratadine 24 hr for about 4 months and past 3 months kept losing a lot of hair. Found bald spot few days ago and doc says alopecia areata. I saw a few postings on the internet of a correlation and wanted to know it anyone else has

Is 30mg too much in 24 hours?? is medical advice needed

My son experienced nightmares, several night wakenings, disorientation, restlessness, night sweats and a few days after stopping the medication had shortness of breath after exercising (with no previous asthmatic experiences)

Chantix caused me to haveseizures I would not recommend anyone to take this drug find a different way to quit smoking that is safe.

I HAD 1 SHOT OF THIS AND WITHIN 12 HOURS I WENT FROM A VERY NORMAL BLOOD PRESSURE TO WAKING AT 5 A.M. NEXT DAY WITH 198/110 AND 104 PULSE RATE. IT HAS CONTINUED ALL WEEK AFTER AND I'M NOW ON A BLOOD PRESSURE DRUG TO TRY AND CONTROL IT. EVEN WITH DR

can advagraf makke you look like you are pregnant? Can this drug affect your eye site--blurry vision

Does anyone else have insomnia problems, with this drug, was fine before taking it, but now having major trouble getting to sleep and staying asleep.

I have experienced panic attacks, light headedness and pasty mouth taking this drug at 400mg's.

I have sjogren's syndrome. Can i use arcalion or is it not good for me?

Impact of this drug on blood pressure. Should I be worried?

My symptoms were tired, weak, unable to sleep. Was prescribed half of a 15 MG Mirtazapine nightly to help me sleep. Has this drug been successful used as a sleeping aid?

WHAT ARE SIDE EFFECT OF COTRIMOXAXOLE DRUG

<!--StartFragment--> I have advanced Rheumatoid Arthritis. My Left wrist swelled painfully. Had a negative X-ray so Dr (fully informed for current drug regimens and allergies--Aspirin, Penicillin, Thoradamides, Ornate, Iodine, Latex)

DRUG WITHDRAWAL SYNDROME Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Evaluation of Loratadine for Prevention of Pegfilgrastim-Induced Pain
Condition: Pegfilgrastim-induced Back and Leg Pain
Interventions: Drug: Loratadine;   Drug: placebo
Outcome Measures: Prevention of pegfilgrastim-induced back and leg pain by administration of the antihistamine Loratadine;   Identification of adverse events when Loratadine is given to prevent pegfilgrastim-induced back and leg pain;   Incidence of pegfilgrastim-induced back and leg pain
2 Recruiting NOLAN: Naproxen or Loratadine and Neulasta
Condition: Bone Pain in Stage I - III Breast Cancer
Interventions: Drug: Naproxen;   Drug: Loratadine
Outcome Measures: Bone pain (all grade) in cycle 1;   Bone pain (all grade) by cycle (2-4) and across cycles;   Severe (grade 3/4) bone pain by cycle and across cycles;   Subject reported bone pain;   Maximum Subject Reported bone pain;   Area under the Curve for subject-reported bone pain;   Adverse Event and Serious Adverse Events;   Severity of Adverse Events
3 Recruiting Long-Term Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)
Conditions: Rhinitis, Allergic, Perennial;   Rhinitis, Allergic, Nonseasonal
Interventions: Biological: MK-8237 tablets;   Biological: Placebo tablets;   Drug: Rescue Medication: Self-Injectable Epinephrine;   Drug: Rescue Medication: Loratadine tablets;   Drug: Rescue Medication: Olopatadine ophthalmic drops;   Drug: Rescue Medication: Mometasone furoate nasal spray
Outcome Measures: Average Total Combined Rhinitis Score (TCRS);   Number of Participants Who Experience At Least One Adverse Event;   Number of Participants Who Discontinue Study Drug Due to an Adverse Event;   Average Rhinitis Daily Symptom Score (Rhinitis DSS);   Average Total Combined Rhinoconjunctivitis Score (TCS);   Average Rhinitis Daily Medication Score (Rhinitis DMS);   Average Allergic Rhinitis/Rhinoconjunctivitis Symptoms Assessed by Visual Analogue Scale (VAS)
4 Unknown  Combination of Peripheral Nerve Block and DepoDur in Total Knee Joint Replacement
Condition: Arthroplasty, Replacement, Knee
Interventions: Drug: Depodur;   Procedure: sciatic nerve block
Outcome Measures: Postoperative Pain;   Time Required for Placement of Block;   Time to first use of rescue analgesia and PCA;   Total opioid consumption;   Degree of knee flexion (Range of motion);   Day of first ambulation;   Number of days required to achieve a 110° knee flexion;   Number of days of hospitalization;   Need for manipulation of knee joint under general anesthesia;   Secondary effects: nausea and vomiting, pruritus, supplemental oxygen, urinary catheterization;   Satisfaction score