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DRUG WITHDRAWAL SYNDROME and Xanax

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DRUG WITHDRAWAL SYNDROME Symptoms and Causes

Opioids, sometimes called narcotics, are a type of drug. They include strong prescription pain relievers, such as oxycodone, hydrocodone, fentanyl, and tramadol. The illegal drug heroin is also an opioid. Some opioids are made from the opium plant, and others are synthetic (man-made).

A doctor may give you a prescription opioid to reduce pain after you have had a major injury or surgery. You may get them if you have severe pain from health conditions like cancer. Some doctors prescribe them for chronic pain.

Opioids can cause side effects such as drowsiness, mental fog, nausea, and constipation. They may also cause slowed breathing, which can lead to overdose deaths. If someone has signs of an overdose, call 9-1-1:

  • The person's face is extremely pale and/or feels clammy to the touch
  • Their body goes limp
  • Their fingernails or lips have a purple or blue color
  • They start vomiting or making gurgling noises
  • They cannot be awakened or are unable to speak
  • Their breathing or heartbeat slows or stops

Other risks of using prescription opioids include dependence and addiction. Dependence means feeling withdrawal symptoms when not taking the drug. Addiction is a chronic brain disease that causes a person to compulsively seek out drugs, even though they cause harm. The risks of dependence and addiction are higher if you abuse the medicines. Abuse can include taking too much medicine, taking someone else's medicine, taking it in a different way than you are supposed to, or taking the medicine to get high.

Opioid abuse, addiction, and overdoses are serious public health problems in the United States. Another problem is that more women are abusing opioids during pregnancy. This can lead to babies being addicted and going through withdrawal, known as neonatal abstinence syndrome (NAS). Opioid abuse may sometimes also lead to heroin use, because some people switch from prescription opioids to heroin.

The main treatment for prescription opioid addiction is medication-assisted treatment (MAT). It includes medicines, counseling, and support from family and friends. MAT can help you stop using the drug, get through withdrawal, and cope with cravings. There is also a medicine called naloxone which can reverse the effects of an opioid overdose and prevent death, if it is given in time.

To prevent problems with prescription opioids, be sure to follow your doctor's instructions when taking them. Do not share your medicines with anyone else. Contact your doctor if you have any concerns about taking the medicines.

NIH: National Institute on Drug Abuse

Check out the latest treatments for DRUG WITHDRAWAL SYNDROME

DRUG WITHDRAWAL SYNDROME treatment research studies

Xanax clinical trials, surveys and public health registries


Find Drug Side Effect reports



Xanax Side Effects

Anxiety (349)
Insomnia (242)
Depression (220)
Feeling Abnormal (204)
Somnolence (198)
Nausea (194)
Headache (190)
Malaise (176)
Fatigue (172)
Fall (171)
Overdose (159)
Dizziness (157)
Pain (153)
Dyspnoea (145)
Suicide Attempt (143)
Diarrhoea (142)
Hypertension (136)
Confusional State (131)
Convulsion (129)
Agitation (122)
Tremor (83)
Loss Of Consciousness (75)
Sopor (74)
Intentional Overdose (73)
Amnesia (72)
Panic Attack (68)
Nervousness (64)
Back Pain (64)
Chest Pain (61)
Withdrawal Syndrome (61)
Off Label Use (60)
Suicidal Ideation (60)
Weight Increased (60)
Weight Decreased (59)
Blood Pressure Increased (58)
Vomiting (58)
Asthenia (56)
Blood Cholesterol Increased (55)
Death (53)
Road Traffic Accident (52)
Myocardial Infarction (51)
Pruritus (51)
Abdominal Pain Upper (51)
Rash (49)
Aggression (48)
Abnormal Behaviour (47)
Hypotension (46)
Decreased Appetite (46)
Oedema Peripheral (45)
Hallucination (45)

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DRUG WITHDRAWAL SYNDROME Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Bioequivalence Of A Test Alprazolam Sublingual Formulation Compared To A Commercial Sublingual Formulation
Condition: Healthy
Interventions: Drug: alprazolam sublingual tablet commercial;   Drug: alprazolam sublingual tablet test
Outcome Measures: Alprazolam bioavailability assessed as area under the concentration-time curve (AUC) and maximum concentration (Cmax);   Alprazolam time of maximum concentration (Tmax) and half life;   Adverse events, clinical laboratory tests, vital signs
2 Recruiting Imaging the Effects of Zolpidem and Alprazolam in Healthy Volunteers at 3T
Condition: Psychotropic Drugs Effects
Interventions: Drug: Zolpidem;   Drug: Alprazolam;   Drug: Caffeine;   Other: Placebo
Outcome Measures: Change in blood oxygen level-dependent (BOLD) signal as measured with fMRI;   Change in subjective drug effects as measured by self-report questionnaires
3 Unknown  Drug Treatment Validation of Functional Magnetic Resonance Imaging in Generalized Anxiety Disorder
Condition: Generalized Anxiety Disorder
Interventions: Drug: Alprazolam (Xanax);   Drug: Placebo
Outcome Measures: To evaluate the effect of an anxiolytic drug versus placebo on brain activity at rest and during emotional stimuli using fMRI.;   To evaluate the effects of an anxiolytic drug versus placebo on eye blink startle response at rest and during emotional stimuli (anxiety potentiated startle, APS) as well as on clinical scales.;   To correlate the fMRI measurements with the clinical/behavioral measurements of efficacy.
4 Unknown  Effects of Buspar on Depressive Symptom Improvement and Neuroprotection in Patients With Anxiety Disorder
Condition: Anxiety Disorder
Interventions: Drug: buspirone+alprazolam;   Drug: alprazolam;   Other: healthy controls
Outcome Measures: change from baseline in depressive symptom scores at 8 weeks;   change from baseline in depressive symptom scores at 4 weeks;   change from baseline in depressive symptom scores at 1 week;   change from baseline in anxiety symptom scores at 8 weeks;   change from baseline in anxiety symptom scores at 4 weeks;   change from baseline in anxiety symptom scores at 1 week;   changes from baseline in brain structure, function, and biochemical metabolism, analyzed using the computational approach;   number of participants with adverse events
5 Recruiting Gabapentin Treatment of Benzodiazepine Dependence
Condition: Benzodiazepine Dependence
Interventions: Drug: gabapentin;   Drug: Placebo
Outcome Measure: Abstinence from Benzodiazepine use
6 Recruiting Effects of a CRF1 Receptor Antagonist on Human Startle in Normal Female Volunteers
Condition: Anxiety Disorders
Intervention:
Outcome Measure:
7 Recruiting Influence of Anesthesia Technique on Postoperative Evolution After Urogenital Surgical Interventions
Conditions: Anesthesia; Reaction;   Adverse Effect of Other General Anesthetics;   Adverse Anesthesia Outcome;   Acute Kidney Injury
Interventions: Procedure: epidural catheter insertion;   Procedure: robot assisted laparoscopic urogenital surgery
Outcome Measures: acute kidney injury;   postoperative outcome
8 Recruiting Effects of Hallucinogens and Other Drugs on Mood and Performance
Condition: Healthy
Intervention: Drug: Hallucinogens and psychoactive substances
Outcome Measures: Rating of "Drug Liking" on the End of Day Questionnaire;   Hallucinogen Rating Scale