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DRY EYE and Genteal

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DRY EYE Symptoms and Causes

You may only think of tears as those salty drops that fall from your eyes when you cry. Actually, your tears clean your eyes every time you blink. Tears also keep your eyes moist, which is important for your vision.

Tear glands produce tears, and tear ducts carry the tears from the glands to the surface of your eye. Problems with the tear system can include too many tears, too few tears, or problems with the tear ducts. Treatment of the problem depends on the cause.

Check out the latest treatments for DRY EYE

DRY EYE treatment research studies

Genteal clinical trials, surveys and public health registries


Find Drug Side Effect reports



Genteal Side Effects

Eye Irritation (30)
Eye Pain (25)
Vision Blurred (18)
Eye Pruritus (17)
Ocular Hyperaemia (16)
Pruritus (16)
Cataract (11)
Cataract Operation (9)
Dry Eye (8)
Eyelid Disorder (8)
Corneal Abrasion (7)
Eye Swelling (6)
Foreign Body Sensation In Eyes (6)
Lacrimation Increased (6)
Weight Decreased (4)
Fall (4)
Eye Infection (4)
Hypersensitivity (4)
Instillation Site Pain (3)
Corneal Disorder (3)
Keratitis (3)
Visual Acuity Reduced (3)
Superficial Injury Of Eye (3)
Ulcerative Keratitis (3)
Cerebrovascular Accident (2)
Cellulitis (2)
Anorexia (2)
Anaphylactic Shock (2)
Condition Aggravated (2)
Blepharospasm (2)
Death (2)
Pneumonia (2)
Dyspnoea (2)
Abnormal Sensation In Eye (2)
Diplopia (2)
Depression (2)
Conjunctival Ulcer (2)
Eye Inflammation (2)
Headache (2)
Intraocular Pressure Increased (2)
Hallucination, Visual (2)
Furuncle (2)
Eye Operation (2)
Large Intestinal Obstruction Reduction (2)
Lung Disorder (2)
Eye Discharge (2)
Plastic Surgery (2)
Memory Impairment (2)
Malaise (2)
Eye Burns (2)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

DRY EYE Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  A Placebo Controlled Comparison of Topical Zirgan Versus Genteal Gel for the Treatment of Adenovirus Conjunctivitis
Conditions: Keratoconjunctivitis Due to Adenovirus;   Viral Shedding
Interventions: Drug: Zirgan;   Drug: Genteal gel
Outcome Measures: Time to Viral Eradication;   Development of sub-epithelial infiltrates;   Degree of Bulbar conjunctival Injection;   Second eye involvment
2 Recruiting A Trial of Topical Dexamethasone Versus Artificial Tears for Treatment of Viral Conjunctivitis
Condition: Viral Conjunctivitis
Interventions: Drug: dexamethasone 0.1%/povidone-iodine 0.4%;   Drug: Artificial Tears
Outcome Measures: Conjunctival injection;   Conjunctival chemosis
3 Unknown  Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma
Conditions: Ocular Surface Disease;   Glaucoma
Interventions: Drug: hydroxypropylmethylcellulose;   Drug: sodium hyaluronate
Outcome Measures: Ocular surface index score;   Eye lid inflammation, corneal staining score, tear break up time and tear volume
4 Not yet recruiting Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension
Conditions: Glaucoma;   Ocular Hypertension
Interventions: Drug: bimatoprost 0.01%;   Drug: travoprost 0.004%;   Drug: timolol 0.5%;   Drug: hypromellose 0.3%
Outcome Measure: Intraocular Pressure (IOP) in the Study Eye
5 Recruiting An Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension
Conditions: Glaucoma;   Ocular Hypertension
Interventions: Drug: bimatoprost 0.01%;   Drug: travatan 0.004%;   Drug: timolol 0.5%;   Drug: hypromellose 0.3%
Outcome Measure: Intraocular Pressure (IOP) in the Study Eye
6 Recruiting Hydroxypropyl Beta Cyclodextrin for Niemann-Pick Type C1 Disease
Condition: Niemann-Pick Disease, Type C1
Intervention: Drug: 2-hydroxypropyl-beta-cyclodextrin
Outcome Measures: 24-hydroxycholesterol Area under the curve;   Hearing loss.
7 Recruiting The Utility of in Vivo Confocal Microscopy to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With Dry Eye Disease
Condition: Dry Eye Disease
Interventions: Drug: Lotemax;   Drug: Artificial Tears
Outcome Measures: In Vivo Confocal Microscopy (IVCM): Superficial corneal epithelial cells: Density, size, and hypereflectivity;   In Vivo Confocal Microscopy: Corneal subbasal immune dendritiform cells: Density, size, and cell field;   In Vivo Confocal Microscopy: Corneal subbasal nerves: Number and length of the main nerves and the branches;   Ocular Signs: Corneal epitheliopathy;   Ocular Signs: Conjunctival epitheliopathy;   Ocular Signs: Tear Break Up Time (TBUT);   Ocular Signs: Schirmer's Test with Anesthesia;   Ocular Signs: Intraocular pressure (IOP) by measure of applanation tonometry;   Ocular Symptoms: Ocular Surface Disease Index (OSDI) questionnaire;   Ocular Symptoms: • Symptom Assessment iN Dry Eye (SANDE) questionnaire
8 Unknown  Comparison of Combination Antibiotics Eyedrop to Artificial Tear in Hordeolum After Incision and Curettage
Condition: Hordeolum
Interventions: Drug: neomycin sulfate, polymyxin B sulfate and gramicidin;   Drug: Artificial tear
Outcome Measures: Pain scale;   Mass size and duration of cure
9 Recruiting Efficacy and Safety of Fluorometholone (FML) in Dry Eye Disease (Keratoconjunctivitis Sicca)
Condition: Dry Eye
Interventions: Drug: FML 0.1% eyedrops;   Drug: Liquifilm artificial tears eyedrops
Outcome Measures: Fluorescein corneal staining;   Symptom Assessment in Dry Eye (SANDE) I and II questionnaire;   Tear inflammatory molecule levels;   Best corrected visual acuity;   Biomicroscopy findings at slit lamp examination;   Adverse events during the trial;   Other Efficacy Measures;   Intraocular pressure (IOP) and fundus examination
10 Recruiting Effects of Conventional Dry Eye Treatments on the Ocular Surface Response to Low Humidity Environment in Patients With Keratoconjunctivitis Sicca
Conditions: Keratoconjunctivitis Sicca;   Dry Eye Syndrome
Intervention: Drug: dexamethasone, artificial tears
Outcome Measure: Changes in ocular surface measured by routine opthalmic dyes
11 Recruiting Effect of Topical Glaucoma Therapy on Tear Film Stability in Healthy Subjects
Condition: Healthy
Interventions: Drug: Timoptic® 0.5%;   Drug: Timophtal sine® 0.5%;   Device: Genteal HA®;   Device: Hylo-Comod®;   Device: Thealoz®
Outcome Measures: Tear film thickness;   Break up time (BUT)
12 Recruiting Fluorometholone as Ancillary Therapy for TT Surgery
Conditions: Trichiasis;   Trachoma;   Bilamellar Tarsal Rotation
Interventions: Drug: Fluorometholone 0.1% ophthalmic solution;   Other: Artificial tears (Placebo)
Outcome Measures: Safety assessments;   Recurrence of trichiasis in the study eye
13 Not yet recruiting Assessment of Tear Film Thickness by Optical Coherence Tomography in Healthy Subjects and Subjects With Dry Eye Disease
Condition: Dry Eye Syndrome
Interventions: Device: Genteal HA® Eye Drops (NOVARTIS, Switzerland);   Other: Physiological Sodium Chloride solution (0,9%)
Outcome Measures: Tear film thickness;   Schirmer I Test;   Tear Break Up Time;   Ocular Surface Disease Index
14 Recruiting A Phase IV, Randomized, Parallel Group, Investigator-Masked Evaluation of the Effect of Loteprednol Etabonate Ophthalmic Gel 0.5% on the Initiation of Dry Eye Treatment With Restasis®
Condition: Dry Eye Disease
Interventions: Drug: Loteprednol etabonate;   Drug: Artificial Tears;   Drug: Restasis
Outcome Measures: Fluorescein corneal staining scores;   Lissamine green conjunctival staining
15 Not yet recruiting Prostaglandin F2-alpha Eye Drops in Thyroid Eye Disease (Bima Study)
Condition: Graves' Ophthalmopathy
Interventions: Drug: Bimatoprost;   Drug: Eye drop solution
Outcome Measures: The primary endpoint of this study will be comparison of the change in ophthalmometry readings over the two 3 month treatment periods.;   Change in quality of life scores on the TED quality of life questionnaire (GO-QOL);   Intraocular pressures;   Side effects;   Health economic outcomes
16 Recruiting Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol
Conditions: Sturge Weber Syndrome;   Port Wine Mark
Interventions: Drug: Timolol;   Drug: Preservative free artificial tear gel.
Outcome Measure: Appearance of Port-wine Mark at treatment site
17 Recruiting Steroids After Laser Trabeculoplasty for Glaucoma
Condition: Glaucoma
Interventions: Drug: Prednisolone 1%;   Drug: Diclofenac 0.1%;   Drug: Artificial Tears
Outcome Measures: Intraocular pressure (IOP) lowering;   Intraocular inflammation
18 Unknown  Aqueous Humor Dynamics and Brimonidine
Condition: Intraocular Pressure
Interventions: Drug: Brimonidine;   Drug: Artificial tears
Outcome Measure: Aqueous Humor Dynamics
19 Recruiting Postoperative Subtenons Anesthesia for Postoperative Pain in Pediatric Strabismus Surgery
Condition: Strabismus
Interventions: Drug: subtenons anesthetic - preservative-free bupivacaine 0.75%;   Drug: topical anesthetic - 0.5 cc of lidocaine 3.5% ophthalmic gel;   Drug: topical control - 0.5 cc of Hypromellose 0.3% gel;   Drug: subtenons control - 0.5 cc of Normal Saline
Outcome Measures: Average pain score over the first 30 post-operative minutes using the CHEOPS scale;   Peak pain score in the first 30 minutes;   Total narcotic and anti-emetic use during post-operative recovery;   Negative postoperative behavior score on the PHBQ (post hospitalization behavioral questionnaire);   Change in pain score
20 Unknown  Evaluation of Blood as a Submucosal Cushion During Endoscopic Polypectomy and Mucosal Resection
Condition: Large Polyps in the Gastrointestinal Tract
Interventions: Drug: Autologous blood injection;   Drug: Normal saline;   Drug: HPMC
Outcome Measures: Duration of the submucosal cushion Ease of injection Ability to complete lesion removal Post-procedure complications;   Ability to perform lesion removal Ability to visualize during the procedure