DYSPEPSIA Symptoms and Causes

Nearly everyone has had indigestion at one time. It's a feeling of discomfort or a burning feeling in your upper abdomen. You may have heartburn or belch and feel bloated. You may also feel nauseated, or even throw up.

You might get indigestion from eating too much or too fast, eating high-fat foods, or eating when you're stressed. Smoking, drinking too much alcohol, using some medicines, being tired, and having ongoing stress can also cause indigestion or make it worse. Sometimes the cause is a problem with the digestive tract, like an ulcer or GERD.

Avoiding foods and situations that seem to cause it may help. Because indigestion can be a sign of a more serious problem, see your health care provider if it lasts for more than two weeks or if you have severe pain or other symptoms. Your health care provider may use x-rays, lab tests, and an upper endoscopy to diagnose the cause. You may need medicines to treat the symptoms.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

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Nexium Side Effects

Gastrooesophageal Reflux Disease (3970)
Malaise (2729)
Dyspepsia (2294)
Pain (1309)
Vomiting (1209)
Osteoporosis (1201)
Abdominal Pain Upper (1180)
Abdominal Discomfort (946)
Off Label Use (840)
Fall (820)
Gastric Disorder (817)
Chest Pain (787)
Nausea (778)
Diarrhoea (704)
Aphagia (702)
Diabetes Mellitus (634)
Cerebrovascular Accident (610)
Headache (579)
Adverse Event (578)
Dyspnoea (575)
Arthritis (563)
Multiple Fractures (556)
Myocardial Infarction (551)
Hypertension (515)
Dysphagia (504)
Feeling Abnormal (495)
Insomnia (477)
Neoplasm Malignant (466)
Weight Decreased (456)
Throat Irritation (451)
Nasopharyngitis (441)
Hiatus Hernia (439)
Cough (436)
Pneumonia (430)
Bone Disorder (402)
Dizziness (378)
Back Pain (374)
Cardiac Disorder (360)
Depression (353)
Abdominal Pain (338)
Anxiety (334)
Regurgitation (327)
Road Traffic Accident (324)
Ulcer (313)
Pain In Extremity (309)
Fatigue (302)
Abdominal Distension (297)
Dysphonia (289)
Oropharyngeal Pain (286)
Chronic Obstructive Pulmonary Disease (280)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
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Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
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Zyrtec(1669)

Recent Reviews

Both feet and legs swelled up after third day of 40 mg caps

Does anyone have abdominal pain from long term Nexium use?

Extreme abdominal pain Ocassional headache Lots of air in upper and lower abdominal

Extreme dryness in then mouth and throat requiring ambulance once

Foul metallic taste in mouth,itchy skin,thrush :(

Has anyone experienced a reuction in the immune system to picking up cold and flue viruses. Since taking Nexium I am constantly catching every Every type of cold, sore throat or chest infection going around.

Hi! Some years ago I took nexium for v. severe gerd, with haemorrhage. From the time I started it, suddenly my gastric system was totally upset, where it hadn't previously. Because I wasn't digesting properly, my immune system was affected, and hav

High gloucose level?

I am fairly new to this i have been on inexium for 2 months because i was told i had barret barrett's oesophagus. pre cancer my stomach is burning all the time.i am now not wanting to take the tablets .what will happen if i stop.my doctor said the ca

I am taking mexium 20 mg regularly for last 1.5 years. Recent blood test have shown high level of liver enzymes . I am a non drinker and have never had any jaundice or any immunisation of hepatitis. Nexium definately messed up my healthy liver

After i took cetrum i felt dull stomach pain dyspepsia and some gastointestinal problems i stoped it and did not take it next day but i contaniue to have this problem for more than 4 days

At about the third week of 500mg 2x a day, I developed severe dyspepsia ; abdominal pain, gas, and bloating. I also could not eat, had mouth sores, and fatique. I stopped taking the drug. It is now 4 days later, and I still have dyspepsia,

Good Afternoon, i am located in Africa. I have been taking Sompraz to treat dyspepsia. I am pregnant however and i wanted to know if it can have any effect on the unborn child?

My daughter has just been prescriped Atenolol for treating her dyspepsia. When I picked up the prescription at the pharmacy. They had said that they have never heard of Atenolol being used to treat dyspepsia so now Im confused. I have a call into

DYSPEPSIA Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
RankStatusStudy
1 Recruiting Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia
Conditions: Dyspepsia;   Compliance;   Depression
Interventions: Drug: Omeprazole;   Drug: Flupentixol and Melitracen Tablets(for Dyspepsia symptoms) + Omeprazole;   Drug: Flupentixol and Melitracen Tablets(for depression symptoms) + Omeprazole;   Drug: Flupentixol and Melitracen Tablets(without explanation) + Omeprazole
Outcome Measures: compliance of antidepressant medication;   Dyspepsia symptom questionnaire;   psychiatric symptom on Hospital Anxiety and Depression Scale;   quality of life rating;   adverse reaction
2 Unknown Esomeprazole or Famotidine in the Management of Aspirin Related Non-Ulcer Dyspepsia
Conditions: Aspirin;   Dyspepsia
Interventions: Drug: esomeprazole;   Drug: Famotidine
Outcome Measures: Treatment success : The HKDI is less than 16. Treatment was considered to have failed if a patient had taken medication for Dyspepsia (other than antacids) during the study period;   Treatment success: no significant Dyspepsia defined by the Global Dyspepsia Score
3 Unknown Effect Of Itopride On Gastric Emptying And Accommodation In Patients With Functional Dyspepsia
Conditions: Functional Dyspepsia;   Gastric Emptying;   Gastric Accommodation
Interventions: Drug: Itopride,;   Drug: Placebo
Outcome Measures: To assess the effect of Itopride on Gastric Emptying,accommodation and capacity of tolerating a nutrient drink in patients with Functional Dyspepsia;   To assess the effect of Itopride on symptom improvement in patient with Functional Dyspepsia
4 Recruiting Acupuncture for Patients With Function Dyspepsia
Conditions: Functional Dyspepsia;   Postprandial Distress Syndrome
Interventions: Other: acupuncture;   Other: sham acupuncture
Outcome Measures: The proportion of participants reporting complete absence of dyspeptic symptoms;   validated Leeds Dyspepsia Questionnaire;   Nepean Dyspepsia index;   adverse events in each group
5 Unknown Corticotropin Releasing Hormone (CRH) Responsiveness in Children With Functional Dyspepsia
Condition: Functional Dyspepsia
Intervention: Drug: Acthrel
Outcome Measures: Heart rate variability;   Stress profile;   plasma protein levels;   BASC 2 profile;   STICSA-C;   GI symptom severity scale
6 Recruiting Ghrelin and Gastric Emptying in Children With Functional Dyspepsia
Condition: Functional Dyspepsia
Intervention:
Outcome Measures: Children with FD: exploration of relationships between ghrelin concentration, liquid gastric emptying, and Dyspepsia subtype;   Children with FD: SUBJECTIVE SYMPTOM SEVERITY and correlations between plasma ghrelin concentrations (acyl and desacyl) and gastric emptying.
7 Unknown Gabapentin in Functional Dyspepsia Refractory to Proton Pump Inhibition
Condition: Functional Dyspepsia
Interventions: Drug: Gabapentin;   Drug: Placebo
Outcome Measures: The primary outcome will be the adequacy of symptom control during the last week of the study.;   Secondary outcomes equate Dyspepsia symptoms with quality of life. The Nepean Dyspepsia Index scores patients on five categories while the Global Overall Symptom Scale measures the severity of Dyspepsia on a 1-7 scale.
8 Unknown Mirtazapine Versus Placebo in Functional Dyspepsia
Condition: Functional Dyspepsia
Intervention: Drug: Mirtazapine
Outcome Measures: Difference in Dyspepsia symptom scores week 8 versus week 0;   Individual symptom severities;   Nepean Dyspepsia index for quality of life in functional Dyspepsia
9 Not yet recruiting Rebamipide in Combination With Esomeprazole in the Management of Asian Patients With Functional Dyspepsia
Condition: Dyspepsia
Interventions: Drug: Rebamipide;   Drug: Placebo (for Esomeprazole);   Drug: Esomeprazole
Outcome Measures: Dyspepsia symptoms;   quality of life
10 Recruiting Effect of Acupuncture on Patients With Functional Dyspepsia: a Multi-center, Randomized, Waitlist-controlled Trial
Condition: Functional Dyspepsia
Intervention: Device: Acupuncture
Outcome Measures: Proportion of responders;   Nepean Dyspepsia Index - Korean version (NDI-K);   EuroQol-5 Dimension (EQ-5D);   Functional Dyspepsia-Related Quality of Life (FD-QoL) Questionnaire;   Beck's Depression Inventory (BDI);   The State-Trait Anxiety Inventory (STAI);   Ghrelin hormone measurement (1. Total ghrelin, 2. Deacylated ghrelin);   Genotype analysis by Axiom® exome genotyping arrays
11 Unknown Functional Dyspepsia - Effect of Acid-Reducing Treatment and Information on Various Types of Dysmotility
Condition: Dyspepsia
Interventions: Procedure: Individualized and comprehensive information;   Drug: Lanzo Melt
Outcome Measure: Improvement of symptom score
12 Recruiting BRAVO Study for Functional Dyspepsia
Conditions: Dyspepsia;   Gastroesophageal Reflux
Interventions: Drug: Esomeprazole 20mg;   Other: Placebo
Outcome Measures: The primary outcome measure is the proportion of patients who report positive response to adequate relief of dyspeptic symptoms at week 8.;   The secondary outcome measures include dyspeptic symptom scores, symptom association probability of dyspeptic symptoms in relation to esophageal pH of less than 4 as measured at 1 cm above SCJ.
13 Recruiting SSRI Study for Functional Dyspepsia (SS)
Conditions: Dyspepsia;   Anxiety;   Depression
Interventions: Drug: Escitalopram;   Other: Placebo
Outcome Measures: To evaluate the change of serotonin and ghrelin level in blood plasma before and after treatment;   To measure expression of serotonin and ghrelin blood plasma, the rate of adequate relief using global symptom assessment, symptom scores and the fullness rating of the Fullness Rating Scale (FRS) during satiety test
14 Unknown Mucosal Barrier Defects in Functional Dyspepsia by Confocal Laser Endomicroscopy
Condition: Functional Dyspepsia
Intervention:
Outcome Measures: Specific microscopic changes in the gastric mucosa as seen under the confocal endomicroscope;   the relationship among minimal changes, FD symptoms , neuropeptides and immune responses.
15 Recruiting Comparison of Pantoprazole and Ranitidine in Dyspepsia
Condition: Dyspepsia
Interventions: Drug: Pantoprazole;   Drug: Ranitidine
Outcome Measures: Visual analogue scale score;   Need for additional drug
16 Unknown Safety Study of a Chinese Herbal Formula Simotang Oral Liquid for the Treatment of Functional Dyspepsia
Conditions: Functional Dyspepsia(FD) Was Studied;   Effect of Simotang on FD Was Studied
Intervention:
Outcome Measures: Improvement of gastrointestinal Symptom as efficacy and the Number of Participants with Adverse Events as a Measure of Safety;   Chinese version of the Nepean Dyspepsia Index as a Measure of efficacy
17 Unknown The Efficacy of Pantoprazole Treatment in Patients With Functional Dyspepsia
Condition: Nonulcer Dyspepsia
Interventions: Drug: Pantoprazol;   Drug: Folic Acid
Outcome Measure: Effectiveness of pantoprazole treatment in patients with functional Dyspepsia measured by symptoms scale.
18 Not yet recruiting The Efficacy and Safety Study of Rikkunshito in Patients With Functional Dyspepsia
Condition: Functional Dyspepsia
Interventions: Drug: Rikkunshito;   Drug: Rikkunshito placebo
Outcome Measures: Global assessment of overall treatment efficacy (OTE);   Global overall symptom (GOS)
19 Unknown Does Visceral Manipulation Works in Treating Functional Dyspepsia?
Condition: Functional Dyspepsia
Interventions: Procedure: Visceral Manipulation;   Drug: PPIs and/or Domperidone
Outcome Measure: FD symptoms: Bothersome postprandial fullness
 / Early satiation / Epigastric pain / Epigastric burning
20 Recruiting Rifaximin for Functional Dyspepsia
Condition: Functional Dyspepsia
Interventions: Drug: Rifaximin;   Drug: Placebo
Outcome Measures: Adequate relief of dyspeptic symptoms at end of treatment;   Individual dyspeptic symptom scores