DYSPEPSIA and Prednisone

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DYSPEPSIA Symptoms and Causes

Nearly everyone has had indigestion at one time. It's a feeling of discomfort or a burning feeling in your upper abdomen. You may have heartburn or belch and feel bloated. You may also feel nauseated, or even throw up.

You might get indigestion from eating too much or too fast, eating high-fat foods, or eating when you're stressed. Smoking, drinking too much alcohol, using some medicines, being tired, and having ongoing stress can also cause indigestion or make it worse. Sometimes the cause is a problem with the digestive tract, like an ulcer or GERD.

Avoiding foods and situations that seem to cause it may help. Because indigestion can be a sign of a more serious problem, see your health care provider if it lasts for more than two weeks or if you have severe pain or other symptoms. Your health care provider may use x-rays, lab tests, and an upper endoscopy to diagnose the cause. You may need medicines to treat the symptoms.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Check out the latest treatments for DYSPEPSIA

➢ DYSPEPSIA treatment research studies

➢ Prednisone clinical trials, surveys and public health registries

Find Drug Side Effect reports

Prednisone Side Effects

Dyspnoea (309)

Pyrexia (283)

Nausea (273)

Pain (263)

Diarrhoea (255)

Arthralgia (247)

Fatigue (246)

Headache (234)

Pneumonia (231)

Pain In Extremity (210)

Asthenia (210)

Vomiting (205)

Dizziness (201)

Oedema Peripheral (198)

Weight Increased (187)

Weight Decreased (175)

Abdominal Pain (172)

Back Pain (169)

Condition Aggravated (161)

Anaemia (156)

Crohn's Disease (113)

Sepsis (110)

Osteonecrosis (105)

Dehydration (104)

Malaise (104)

Fall (101)

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Rash (89)

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Pulmonary Embolism (88)

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Pruritus (83)

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Neutropenia (74)

Deep Vein Thrombosis (73)

Renal Failure Acute (71)

Hyperglycaemia (69)

Muscular Weakness (69)

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Recent Reviews

&gt;:o :'(

3 weeks after i had been given 120m of predisone in a 24 hour period,i started getting dizzy spells severe enough that initially i blacked out while driving,needless to say i havent been driving my car,but i still am experiencing very bad dizzy spell

66 year old male. Good to excellent health. Non smoker, non drinker. Slowly deteriorated till all joints were swollen and eventually I became 99% immobile. Diagnosis? Spotless, Rocky Mountain Spotted Fever. (erlickiosis chaffnesis) Hospitalized, inf

Female patient 39 taking prednisone for asthma. Prednisone 20 mg 4 days on and then one day off/one day onfor8 days. Menstrual type bleeding although not during menstrual period. Severe pelvic cramps and urgency of urination. Swol

I am asthmatic (since I was very little) 36yrs old, took 40mg Prednisone for 8 days - two days later I ovulated and then I started bleeding uncontrollably. Gynae said ovaries failed as blood work tested very low and put me on Duphaston to aid drying

I have taken Prednisone for severe asthma on many occassions (including IV in hospital for 7 days) and suffered severe abdominal pain. Three years ago a gastroscopy revealed I had Duodenal ulcers and Gastritis, most likely caused from the Prednisilo

I take it when i get poison oak or ivy really bad and it takes it away in like 3 days if im fully broken out and i am highly allergic poison ivy, oak and all of that other stuff like that and this stuff helps me tremendously :-D

I take prednione 10mg : 3 tablets once daily for 3 days,then 2 tablets once daily for 3 days,then 1 tabletonce daily for 3 days, then hallf tablets for 4 days. Prednisone give more energy because I have Refractory Anemia with Ringed oblast

I was on a higher dosage - 40mg for 8 days and a few days after I stopped, I started with a 'breakthrough' bleed. Had to have blood tests taken and it showed ovarian failure which DR said could be strongly linked to Prednisone... I am not convinced i

I was recently diagnosed as having rheumatoid arthritis one of the meds prescribed was prednisone one of the side affects that i have noticed is my stomach cramps inthe evening. gonna check to see if I can get a different prescrition

After i took cetrum i felt dull stomach pain dyspepsia and some gastointestinal problems i stoped it and did not take it next day but i contaniue to have this problem for more than 4 days

At about the third week of 500mg 2x a day, I developed severe dyspepsia ; abdominal pain, gas, and bloating. I also could not eat, had mouth sores, and fatique. I stopped taking the drug. It is now 4 days later, and I still have dyspepsia,

Good Afternoon, i am located in Africa. I have been taking Sompraz to treat dyspepsia. I am pregnant however and i wanted to know if it can have any effect on the unborn child?

My daughter has just been prescriped Atenolol for treating her dyspepsia. When I picked up the prescription at the pharmacy. They had said that they have never heard of Atenolol being used to treat dyspepsia so now Im confused. I have a call into

DYSPEPSIA Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.

Rank

Status

Study

Recruiting

Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia

Conditions:	Dyspepsia; Compliance; Depression
Interventions:	Drug: Omeprazole; Drug: Flupentixol and Melitracen Tablets(for Dyspepsia symptoms) + Omeprazole; Drug: Flupentixol and Melitracen Tablets(for depression symptoms) + Omeprazole; Drug: Flupentixol and Melitracen Tablets(without explanation) + Omeprazole
Outcome Measures:	compliance of antidepressant medication; Dyspepsia symptom questionnaire; psychiatric symptom on Hospital Anxiety and Depression Scale; quality of life rating; adverse reaction

Unknown ^†

Esomeprazole or Famotidine in the Management of Aspirin Related Non-Ulcer Dyspepsia

Conditions:	Aspirin; Dyspepsia
Interventions:	Drug: esomeprazole; Drug: Famotidine
Outcome Measures:	Treatment success : The HKDI is less than 16. Treatment was considered to have failed if a patient had taken medication for Dyspepsia (other than antacids) during the study period; Treatment success: no significant Dyspepsia defined by the Global Dyspepsia Score

Unknown ^†

Effect Of Itopride On Gastric Emptying And Accommodation In Patients With Functional Dyspepsia

Conditions:	Functional Dyspepsia; Gastric Emptying; Gastric Accommodation
Interventions:	Drug: Itopride,; Drug: Placebo
Outcome Measures:	To assess the effect of Itopride on Gastric Emptying,accommodation and capacity of tolerating a nutrient drink in patients with Functional Dyspepsia; To assess the effect of Itopride on symptom improvement in patient with Functional Dyspepsia

Recruiting

Acupuncture for Patients With Function Dyspepsia

Conditions:	Functional Dyspepsia; Postprandial Distress Syndrome
Interventions:	Other: acupuncture; Other: sham acupuncture
Outcome Measures:	The proportion of participants reporting complete absence of dyspeptic symptoms; validated Leeds Dyspepsia Questionnaire; Nepean Dyspepsia index; adverse events in each group

Unknown ^†

Corticotropin Releasing Hormone (CRH) Responsiveness in Children With Functional Dyspepsia

Condition:	Functional Dyspepsia
Intervention:	Drug: Acthrel
Outcome Measures:	Heart rate variability; Stress profile; plasma protein levels; BASC 2 profile; STICSA-C; GI symptom severity scale

Recruiting

Ghrelin and Gastric Emptying in Children With Functional Dyspepsia

Condition:	Functional Dyspepsia
Intervention:
Outcome Measures:	Children with FD: exploration of relationships between ghrelin concentration, liquid gastric emptying, and Dyspepsia subtype; Children with FD: SUBJECTIVE SYMPTOM SEVERITY and correlations between plasma ghrelin concentrations (acyl and desacyl) and gastric emptying.

Unknown ^†

Gabapentin in Functional Dyspepsia Refractory to Proton Pump Inhibition

Condition:	Functional Dyspepsia
Interventions:	Drug: Gabapentin; Drug: Placebo
Outcome Measures:	The primary outcome will be the adequacy of symptom control during the last week of the study.; Secondary outcomes equate Dyspepsia symptoms with quality of life. The Nepean Dyspepsia Index scores patients on five categories while the Global Overall Symptom Scale measures the severity of Dyspepsia on a 1-7 scale.

Unknown ^†

Mirtazapine Versus Placebo in Functional Dyspepsia

Condition:	Functional Dyspepsia
Intervention:	Drug: Mirtazapine
Outcome Measures:	Difference in Dyspepsia symptom scores week 8 versus week 0; Individual symptom severities; Nepean Dyspepsia index for quality of life in functional Dyspepsia

Not yet recruiting

Rebamipide in Combination With Esomeprazole in the Management of Asian Patients With Functional Dyspepsia

Condition:	Dyspepsia
Interventions:	Drug: Rebamipide; Drug: Placebo (for Esomeprazole); Drug: Esomeprazole
Outcome Measures:	Dyspepsia symptoms; quality of life

Recruiting

Effect of Acupuncture on Patients With Functional Dyspepsia: a Multi-center, Randomized, Waitlist-controlled Trial

Condition:	Functional Dyspepsia
Intervention:	Device: Acupuncture
Outcome Measures:	Proportion of responders; Nepean Dyspepsia Index - Korean version (NDI-K); EuroQol-5 Dimension (EQ-5D); Functional Dyspepsia-Related Quality of Life (FD-QoL) Questionnaire; Beck's Depression Inventory (BDI); The State-Trait Anxiety Inventory (STAI); Ghrelin hormone measurement (1. Total ghrelin, 2. Deacylated ghrelin); Genotype analysis by Axiom® exome genotyping arrays

Unknown ^†

Functional Dyspepsia - Effect of Acid-Reducing Treatment and Information on Various Types of Dysmotility

Condition:	Dyspepsia
Interventions:	Procedure: Individualized and comprehensive information; Drug: Lanzo Melt
Outcome Measure:	Improvement of symptom score

Recruiting

BRAVO Study for Functional Dyspepsia

Conditions:	Dyspepsia; Gastroesophageal Reflux
Interventions:	Drug: Esomeprazole 20mg; Other: Placebo
Outcome Measures:	The primary outcome measure is the proportion of patients who report positive response to adequate relief of dyspeptic symptoms at week 8.; The secondary outcome measures include dyspeptic symptom scores, symptom association probability of dyspeptic symptoms in relation to esophageal pH of less than 4 as measured at 1 cm above SCJ.

Recruiting

SSRI Study for Functional Dyspepsia (SS)

Conditions:	Dyspepsia; Anxiety; Depression
Interventions:	Drug: Escitalopram; Other: Placebo
Outcome Measures:	To evaluate the change of serotonin and ghrelin level in blood plasma before and after treatment; To measure expression of serotonin and ghrelin blood plasma, the rate of adequate relief using global symptom assessment, symptom scores and the fullness rating of the Fullness Rating Scale (FRS) during satiety test

Unknown ^†

Mucosal Barrier Defects in Functional Dyspepsia by Confocal Laser Endomicroscopy

Condition:	Functional Dyspepsia
Intervention:
Outcome Measures:	Specific microscopic changes in the gastric mucosa as seen under the confocal endomicroscope; the relationship among minimal changes, FD symptoms , neuropeptides and immune responses.

Recruiting

Comparison of Pantoprazole and Ranitidine in Dyspepsia

Condition:	Dyspepsia
Interventions:	Drug: Pantoprazole; Drug: Ranitidine
Outcome Measures:	Visual analogue scale score; Need for additional drug

Unknown ^†

Safety Study of a Chinese Herbal Formula Simotang Oral Liquid for the Treatment of Functional Dyspepsia

Conditions:	Functional Dyspepsia(FD) Was Studied; Effect of Simotang on FD Was Studied
Intervention:
Outcome Measures:	Improvement of gastrointestinal Symptom as efficacy and the Number of Participants with Adverse Events as a Measure of Safety; Chinese version of the Nepean Dyspepsia Index as a Measure of efficacy

Unknown ^†

The Efficacy of Pantoprazole Treatment in Patients With Functional Dyspepsia

Condition:	Nonulcer Dyspepsia
Interventions:	Drug: Pantoprazol; Drug: Folic Acid
Outcome Measure:	Effectiveness of pantoprazole treatment in patients with functional Dyspepsia measured by symptoms scale.

Not yet recruiting

The Efficacy and Safety Study of Rikkunshito in Patients With Functional Dyspepsia

Condition:	Functional Dyspepsia
Interventions:	Drug: Rikkunshito; Drug: Rikkunshito placebo
Outcome Measures:	Global assessment of overall treatment efficacy (OTE); Global overall symptom (GOS)

Unknown ^†

Does Visceral Manipulation Works in Treating Functional Dyspepsia?

Condition:	Functional Dyspepsia
Interventions:	Procedure: Visceral Manipulation; Drug: PPIs and/or Domperidone
Outcome Measure:	FD symptoms: Bothersome postprandial fullness  / Early satiation / Epigastric pain / Epigastric burning

Recruiting

Rifaximin for Functional Dyspepsia

Condition:	Functional Dyspepsia
Interventions:	Drug: Rifaximin; Drug: Placebo
Outcome Measures:	Adequate relief of dyspeptic symptoms at end of treatment; Individual dyspeptic symptom scores