| Rank |
Status |
Study |
| 1 |
Recruiting
|
Acupuncture or MBSR for Patients With Fatigue and MS
| Conditions: |
Fatigue; Multiple Sclerosis |
| Interventions: |
Other: Usual care + acupuncture; Other: usual care+mbsr; Other: usual care |
| Outcome Measures: |
Fatigue severity scale; modified Fatigue impact scale; therapy response rates; expanded disability status scale; multipe sclerosis functional composite scale; beck depression inventory II; Body efficacy expectation; SF-12; HAQUAMS; Costs; overall treatment effect; immune parameters; number of serious adverse events; number of suspected adverse reactions |
|
| 2 |
Recruiting
|
Fatigue and Cardiac Sympathetic Denervation in Parkinson Disease
| Condition: |
Parkinson's Disease |
| Intervention: |
|
| Outcome Measure: |
Comparison of cardiac uptake with Fatigue severity score |
|
| 3 |
Unknown †
|
Development and Evaluation of a Cancer-Related Fatigue Patient Education Program
| Condition: |
Cancer-Related Fatigue |
| Intervention: |
Behavioral: Fatigue Patient Education Program (FIBS) |
| Outcome Measures: |
Fatigue; Quality of Life, Depression and anxiety, physical activity |
|
| 4 |
Not yet recruiting
|
Fatigue Management in HIV
| Condition: |
Fatigue |
| Interventions: |
Behavioral: Sleep and Rhythm Intervention; Behavioral: Dietary Modifications |
| Outcome Measures: |
Morning Fatigue severity; Evening Fatigue severity; Lack of energy - frequency; Lack of energy - severity; Lack of energy - distress; Attrition; Satisfaction with the intervention; Adherence to intervention; Objectively measured sleep duration; Objectively measured sleep quality; Objectively-measured activity; Sleep medication use; Self-reported sleep quality; Depressed mood; Anxious mood; Physical function; Cognitive function; Medication adherence; Daytime sleepiness; Fatigue interference with daytime function; Sleep behavior |
|
| 5 |
Recruiting
|
Cognitive Behavioral Therapy With or Without Armodafinil in Treating Cancer Survivors With Insomnia and Fatigue After Chemotherapy
| Condition: |
Unspecified Adult Solid Tumor, Protocol Specific |
| Interventions: |
Procedure: Quality-of-Life Assessment; Other: Questionnaire Administration; Other: Placebo; Procedure: Fatigue Assessment and Management; Procedure: Sleep Disorder Therapy; Drug: Armodafinil; Procedure: Quality-of-life assessment; Procedure: Management of Therapy; Procedure: Sleep disorder therapy; Procedure: cognitive assessment; Procedure: Quality of Life assessment; Procedure: Fatigue assessment and management; Procedure: Management of therapy and complications; Procedure: Cognitive Assessment; Procedure: Quality of Life Assessment; Procedure: Fatifue assessment and management |
| Outcome Measures: |
Severity of insomnia as assessed by the insomnia severity index and daily sleeep diaries.; Fatigue as assessed by the brief Fatigue index; Adverse Events; Fatigue as assessed by the functional assessment of chronic illness therapy-Fatigue; Sleep latency, wake after sleep onset, and total sleep time |
|
| 6 |
Recruiting
|
Methylphenidate as Treatment Option of Fatigue in Multiple Sclerosis
| Conditions: |
Multiple Sclerosis; Fatigue |
| Interventions: |
Drug: Methylphenidate modified release; Drug: Maltodextrin |
| Outcome Measures: |
Change of Fatigue as measured by Fatigue Severity Scale; Change of Fatigue as measured by Modified Fatigue Impact Scale (MFIS) |
|
| 7 |
Recruiting
|
Treatment of Post-Traumatic Brain Injury (Post-TBI) Fatigue With Light Therapy
| Conditions: |
Traumatic Brain Injury; Fatigue |
| Interventions: |
Device: Bright White Light (BWL); Device: Dim Red Light (DRL) |
| Outcome Measures: |
Multidimensional Assessment of Fatigue (MAF); TBI-QOL Fatigue; Neuro-QOL Depression and Sleep; Epworth Sleepiness Scale (ESS); CNS Vital Signs TBI Rehab Toolbox; Cognitive Failures Questionnaire; Neuro-QOL Anxiety; Actiwatch Spectrum; Satisfaction with Life Scale; Treatment Satisfaction Questionnaire for Medication; Credibility/Expectancy Questionnaire |
|
| 8 |
Recruiting
|
Biomarkers of Fatigue Related to Adjuvant Chemotherapy for Breast Cancer
| Conditions: |
Fatigue; Breast Cancer |
| Intervention: |
|
| Outcome Measure: |
Potential biomarkers related to chemotherapy induced Fatigue |
|
| 9 |
Not yet recruiting
|
Yoga Skills Training or Attention Control for Reducing Fatigue and Depressive Symptoms During Chemotherapy in Patients With Stage II-IV Colorectal Cancer
| Conditions: |
Depressive Symptoms; Fatigue; Psychosocial Effects of Cancer and Its Treatment; Stage IIA Colon Cancer; Stage IIA Rectal Cancer; Stage IIB Colon Cancer; Stage IIB Rectal Cancer; Stage IIC Colon Cancer; Stage IIC Rectal Cancer; Stage IIIA Colon Cancer; Stage IIIA Rectal Cancer; Stage IIIB Colon Cancer; Stage IIIB Rectal Cancer; Stage IIIC Colon Cancer; Stage IIIC Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
| Interventions: |
Behavioral: Yoga Skills Training (YST); Other: questionnaire administration; Other: Fatigue and depressive symptom assessment and management; Other: psychological stress assessment; Other: laboratory biomarker analysis; Other: Attention Control |
| Outcome Measures: |
Changes in Fatigue (recalled); Changes in depressive symptoms (recalled and daily); Changes in daily Fatigue; Changes in psychological stress (daily and recalled) as assessed by Perceived Stress Scale (PSS); Regulation of psychological stress (daily and recalled) as assessed by Positive and Negative Affect Schedule-Expanded Form and Cancer Behavior Inventory |
|
| 10 |
Recruiting
|
Fire Fighter Fatigue Management Program: Operation Fight Fatigue
| Conditions: |
Shift-Work Sleep Disorder; Insomnia; Restless Leg Syndrome; Obstructive Sleep Apnea; Impaired Driving |
| Interventions: |
Behavioral: Sleep health education provided via a web-based program; Other: Sleep disorder detection and treatment; Other: Optimization of Sleep in Fire Station |
| Outcome Measures: |
Sleep and health screening of firefighters using a composite of survey instruments; Composite of firefighter information provided by the participating fire department; Sleep and performance of firefighters measured by a composite of physiological monitoring; Documentation of motor vehicle crashes (MVC), and reported injuries; Employment verification as a firefighter of all participants; Composite of firefighter health information |
|
| 11 |
Recruiting
|
Oral Testosterone for Fatigue in Male Multiple Sclerosis Patients
| Conditions: |
Multiple Sclerosis; Fatigue |
| Interventions: |
Drug: Testosterone undecanoate; Drug: placebo |
| Outcome Measures: |
Change in Fatigue (measured with Modified Fatigue Impact Scale [M-FIS]); Change in Fatigue as measured on a visual analog scale (VAS); Quality of life as measured with the Aging Males' Symptoms (AMS) scale; Neurological status as measured with the Expanded Disability Status Scale (EDSS); Number of participants with , type and severity of adverse events |
|
| 12 |
Unknown †
|
Acupuncture for the Treatment of Chronic Post-Chemotherapy Fatigue
| Condition: |
Fatigue |
| Interventions: |
Procedure: Acupuncture; Procedure: Placebo Acupuncture |
| Outcome Measures: |
To determine whether acupuncture reduces chronic Fatigue after chemotherapy more effectively than placebo; To examine the long term effects of acupuncture treatment on Fatigue; To examine predictors of response to acupuncture treatment in terms of baseline symptoms, hemoglobin, age, sex, time since chemotherapy, and concurrent treatment; To examine the effect of acupuncture on levels of physical activity and quality of life |
|
| 13 |
Recruiting
|
Exercise in Lessening Fatigue Caused by Cancer in Patients Undergoing Chemotherapy
| Conditions: |
Fatigue; Unspecified Adult Solid Tumor, Protocol Specific |
| Intervention: |
Behavioral: exercise |
| Outcome Measures: |
Improvement of cancer-related Fatigue as assessed by the Brief Fatigue Inventory total score at day 41 (after exercise intervention); Improvement of aerobic capacity, strength, and quality of life as assessed by the 6-minute walk test, handgrip dynamometry, and Functional Assessment of Chronic Illness Therapy-Fatigue total score at day 41 (after exercise intervention) |
|
| 14 |
Recruiting
|
PG2 Treatment for Improving Fatigue Among Advanced Cancer Patients Under Standard Palliative Care
| Condition: |
Cancer-related Fatigue |
| Interventions: |
Drug: Astragalus Polysaccharides 500 mg; Drug: Astragalus Polysaccharides 250 mg |
| Outcome Measures: |
Fatigue Improvement Response Rate; The Fatigue improvement response rate among patients within and between cycles (by BFI-T); The Fatigue improvement by multiple BFI-T score percentage change levels among patients between two study arms; The mean of patients' Fatigue score change from baseline within and between cycles (by BFI-T); Symptoms and Quality of Life Assessments: SS11 from EORTC QLQ-C30 (including the evaluation of the quality of sleep, appetite, pain, Fatigue, nausea, vomiting and global quality of life); Karnofsky performance score; The correlation between Weight change and the related blood c-reactive protein level; Physical Examination; Labolatory Safety Examination; Incidence of Adverse Events as a Measure of Safety and Tolerability; Vital signs |
|
| 15 |
Recruiting
|
Treatment of Post Stroke Fatigue With a Wakefulness Promoting Agent
| Conditions: |
Stroke; Post Stroke Fatigue |
| Interventions: |
Drug: modafinil; Drug: placebo |
| Outcome Measures: |
Multidimensional Fatigue Inventory (MFI- 20); MFI-20; Fatigue severity scale (FSS); FSS |
|
| 16 |
Not yet recruiting
|
Sodium Oxybate in Patients With Chronic Fatigue Syndrome.
| Condition: |
Chronic Fatigue Syndrome |
| Interventions: |
Drug: Sodium oxybate; Drug: Placebo |
| Outcome Measures: |
Measurement of the effect of sodium oxybate on Fatigue with questionnaires.; Effect of sodium oxybate on sleepiness.; Effect of sodium oxybate on sleepiness; Effect of sodium oxybate on sleep quality.; Effect of sodium oxybate on general health.; Effect of sodium oxybate on pain. |
|
| 17 |
Recruiting
|
Effects of Muscle Fatigue and a Taping Technique on Shoulder Motion of Athletes
| Conditions: |
Shoulder Injury; Muscle Fatigue |
| Interventions: |
Other: Elastic taping applied with tension; Other: Elastic taping applied without tension; Other: Fatigue protocol |
| Outcome Measures: |
Changes in scapular internal/external rotations, upward/downward rotations and anterior/posterior tilt movements; Changes in the median frequency of electromyographic signal from upper and lower trapezius and serratus anterior muscles. |
|
| 18 |
Recruiting
|
American Ginseng to Improve HIV-Associated Fatigue: A Randomized, Placebo-Controlled, Parallel Design, Multiple-Dose Clinical Trial
| Condition: |
HIV/AIDS-associated Fatigue |
| Interventions: |
Drug: American ginseng; Dietary Supplement: Placebo for American ginseng |
| Outcome Measures: |
Change in Fatigue Severity Score; Additional questionnaire will be used to quantify Fatigue, quality of life, symptoms of depression, sleep quality, virologic, immunologic, and inflammatory markers.; Additional questionnaire will be used to quantify Fatigue, inflammatory, immunologic, and virologic markers, and side effects |
|
| 19 |
Recruiting
|
Investigating Molecular-Genetic Correlates of Fatigue Experienced by Cancer Patients Receiving Treatment
| Conditions: |
Cancer; Fatigue |
| Intervention: |
|
| Outcome Measures: |
The primary outcomes of this study are self-reported Fatigue, depression, and quality of life scores of patients before, at midpoint, and at completion of each cycle of their cancer treatment.; White blood cell gene expression; Fatigue, cognitive function, and HRQOL scores; Physical activity levels; Skeletal muscle strength |
|
| 20 |
Recruiting
|
Fatigue Before and After Exercise in Patients With Advanced Cancer Stage
| Condition: |
Fatigue |
| Interventions: |
Other: 10 minute walk; Other: 20 minute walk; Other: 30 minute walk |
| Outcome Measures: |
Fatigue; Quality of life; Anxiety and Depression Evaluation; Patient impression satisfaction |
|
