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GASTROINTESTINAL HAEMORRHAGE and OMEPRAZOLE

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GASTROINTESTINAL HAEMORRHAGE Symptoms and Causes

Your digestive or gastrointestinal (GI) tract includes the esophagus, stomach, small intestine, large intestine or colon, rectum, and anus. Bleeding can come from any of these areas. The amount of bleeding can be so small that only a lab test can find it.

Signs of bleeding in the digestive tract depend where it is and how much bleeding there is.

Signs of bleeding in the upper digestive tract include

  • Bright red blood in vomit
  • Vomit that looks like coffee grounds
  • Black or tarry stool
  • Dark blood mixed with stool

Signs of bleeding in the lower digestive tract include

  • Black or tarry stool
  • Dark blood mixed with stool
  • Stool mixed or coated with bright red blood

GI bleeding is not a disease, but a symptom of a disease. There are many possible causes of GI bleeding, including hemorrhoids, peptic ulcers, tears or inflammation in the esophagus, diverticulosis and diverticulitis, ulcerative colitis and Crohn's disease, colonic polyps, or cancer in the colon, stomach or esophagus.

The test used most often to look for the cause of GI bleeding is called endoscopy. It uses a flexible instrument inserted through the mouth or rectum to view the inside of the GI tract. A type of endoscopy called colonoscopy looks at the large intestine.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Check out the latest treatments for GASTROINTESTINAL HAEMORRHAGE

GASTROINTESTINAL HAEMORRHAGE treatment research studies

OMEPRAZOLE clinical trials, surveys and public health registries


Find Drug Side Effect reports



OMEPRAZOLE Side Effects

Hypomagnesaemia (418)
Diarrhoea (311)
Hypocalcaemia (288)
Nausea (285)
Renal Failure Acute (241)
Vomiting (240)
Dyspnoea (225)
Dizziness (205)
Gastrooesophageal Reflux Disease (191)
Fatigue (168)
Pain (164)
Abdominal Pain (163)
Headache (157)
Malaise (155)
Dyspepsia (152)
Rash (148)
Asthenia (146)
Fall (137)
Abdominal Pain Upper (133)
Confusional State (130)
Hypokalaemia (126)
Condition Aggravated (125)
Pruritus (120)
Arthralgia (118)
Anxiety (117)
Tubulointerstitial Nephritis (116)
Pyrexia (116)
Hyponatraemia (115)
Product Substitution Issue (113)
Paraesthesia (112)
Weight Decreased (111)
Muscle Spasms (109)
Anaemia (106)
Decreased Appetite (104)
Chest Pain (100)
Dysphagia (93)
Convulsion (88)
Dehydration (86)
Depression (84)
Cough (84)
Lethargy (79)
Urticaria (78)
Constipation (78)
Muscular Weakness (78)
Pain In Extremity (76)
Myalgia (76)
Tetany (73)
Tremor (73)
Oedema Peripheral (73)
Pneumonia (72)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

I started taken omeprazole. I ran out of my Nexum well I started itching really bad as it I had bug bites believe me I will never uses this again. I've never had reaction to a med before

I stopped taking Omeprazole 20mg after 4 days because of a side effect, strong palpitations most of the time; I stopped taking them a week ago and still have the palpitations. It's very scary........

I am experiencing itching on my arms, rashes on arms and shoulders, hoarseness, slight dizziness, trouble sleeping and mild headaches. I was prescribed this medication for treatment of bloating caused by my hiatal hernia but can

After 2 weeks skin burning on chest and back nevrous sytoms O:-) :'(

After the 1st week I suffered from severe dizzyness, nausea and headaches. Vomited everything I ate. Yet around 5pm I would always feel relatively human again.

An update, It has only been 3 days & my arm pain has gone!!, for anybody suffering similar symptoms to mine this is what i done...1.STOP taking omeprazole. 2. buy plenty bottled water & drink upto 6 bottles per day. 3 eat healthy (det

Been taking omeprazole for 6 years. during that time diagnosed with osteoporsis. after reading about this seems any proton pump inhibitor can cause. so angry with doctor. looking now for new drug, severe gerd and hiatal hernia.

Both arms , upper arm muscle weakness and pain, , dosage 40mg twice a day

By day 4 severe leg pain, joing pain and cramping and prior never had this pain. All my muscles appear to be tighting up and going to discontinue this ASAP. I guess I am having a very rare reation to Prilosec.

Could the omeprazole be causing sking irritation and the spots that have appeared in my scalp, i was much better when i was taking lanzoperazole

Actuallly the risk of a gastrointestinal bleeding is increased with Pradaxa compared to Warfarin, there isalso an interaction withVerapamil leading to higher plama levels of Pradaxa.

Gastrointestinal. Severe pain starting in middle of chest and wrapping around to middle of back. Tests showed inflamation in stomach and I am now on a bland diet indefinately. Also had trouble swallowing pills and food.&

Hi! Some years ago I took nexium for v. severe gerd, with haemorrhage. From the time I started it, suddenly my gastric system was totally upset, where it hadn't previously. Because I wasn't digesting properly, my immune system was affected, and hav

I am currently involve in a case study about hypercholesterilemia, our patient was given Niacin and Cholestyramine resin(Questran) it was stop because the patient cannot tolerate the flushing and gastrointestinal effects bought by this drugs and repl

I had funny gastrointestinal feelings. Almost as if balloons were popping in my stomach. I had the urge to stool but only the flatulence sound---no stools. I always felt so 'empty' even though I was eating regularly. I stopped at three days I couldn'

I have had Aclasta infusions twice now. On both occasions I experienced gastrointestinal symptoms but three weeks later. One time, it was very acute, right lower quadrant pain, and this year it has been cramps and diarrhea. First time, I felt unwell

I received a dose on May 12 and May 13, 2010 that Friday on May16 i got a really violent headache. By Saturday, I ended up with terrible sweating, fatigue, gastrointestinal problems. On Sunday more of the same. Monday st

I take Vastarel MR once a day. Tired, gastrointestinal increase

I was diagnosed with diabetes 2 years ago and have been taking one diabex xr tablet per day with dinner . Since then I have had gastrointestinal problems which only ease with gastro stop tabletswhen needed. I am frightened to goan

I was diagnosed with diabetes 2 years ago. I take one tablet a day with dinner, Since taking diabex I have cramps, and diarrea and gastrointestinal problems . My life is becoming a series of toilet seeking on journeys and I hate travelling. Could thi

GASTROINTESTINAL HAEMORRHAGE Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Management of Myocardial Injury After Noncardiac Surgery Trial
Condition: Myocardial Injury After Noncardiac Surgery (MINS)
Interventions: Drug: Dabigatran;   Drug: Placebo (for Dabigatran);   Drug: Omeprazole;   Drug: Placebo (for Omeprazole)
Outcome Measures: Major vascular complication (for Dabigatran);   Major upper gastrointestinal complication (for Omeprazole);   Individual secondary outcomes for Dabigatran;   Upper gastrointestinal complication for Omeprazole;   Major vascular complication for Omeprazole;   Individual secondary outcomes for Omeprazole;   Safety outcomes for Dabigatran;   Safety outcomes for Omeprazole
2 Unknown  Comparison of Oral Rabeprazole vs. iv Omeprazole in Mild to Moderate Nonvariceal Upper Gastrointestinal Bleeding
Condition: Nonvariceal Upper Gastrointestinal Bleeding
Interventions: Drug: Intravenous Omeprazole;   Drug: Oral Rabeprazole
Outcome Measure: This study aims to compare the effect of three-day oral rabeprazole and iv Omeprazole on bleeding control in patients with mild to moderate non-variceal UGIB.
3 Not yet recruiting Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN)
Condition: Acute Coronary Syndromes
Interventions: Drug: Omeprazole;   Drug: Pantoprazole
Outcome Measures: Platelet aggregation rate(AA 、ADP);   clinical adverse events
4 Recruiting Pilot Trial Of Omeprazole in Idiopathic Pulmonary Fibrosis (IPF)
Condition: Idiopathic Pulmonary Fibrosis
Interventions: Drug: Omeprazole;   Drug: Matched placebo
Outcome Measures: objectively measured cough frequency;   symptoms of cough;   reflux symptoms;   acid and non-acid reflux;   vital capacity (VC) & transfer factor for carbon monoxide (Tco);   6 minute walk distance;   assess amount of inflammation in lung;   lung infection rate;   adverse events rate
5 Recruiting Comparison of the Gastric Acid Suppressive Effects of EsOmeprazole and Generic Omeprazole
Condition: Gastric Acid
Interventions: Drug: EsOmeprazole first;   Drug: Generic Omeprazole first
Outcome Measures: Median intragastric pH and percentage of time that intragastric pH is above 4;   Nocturnal acid breakthrough, defined as at least 60 continuous minutes of intragastric pH below 4 occurring between 10pm and 6 am and adverse events
6 Recruiting Gastroesophageal Reflux Treatment in Scleroderma
Conditions: Gastroesophageal Reflux Disease;   Systemic Sclerosis;   Scleroderma
Interventions: Drug: Alginic acid;   Drug: placebo (for domperidone);   Drug: Domperidone;   Drug: placebo (of alginic acid)
Outcome Measures: Changing severity of heart burn and regurgitation of SSc related Omeprazole resistant GERD evaluated by visual analogue score (VAS);   changing of frequency of symptoms in SSc related Omeprazole resistant GERD evaluated by frequency scale for the symptoms of GERD (FSSG) and the quality of life which is evaluated by EQ-5DTM (by EuroQol Group);   the prevalence of Omeprazole-resistant GERD in SSc after 4 weeks treatment with Omeprazole
7 Unknown  Impact of Omeprazole and Fluvoxamine on Platelet Response to Clopidogrel
Condition: Drug Interaction of Clopidogrel
Interventions: Drug: Omeprazole;   Drug: fluvoxamine;   Drug: placebo
Outcome Measure: platlet reactivity in response to clopidogrel
8 Recruiting Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia
Conditions: Dyspepsia;   Compliance;   Depression
Interventions: Drug: Omeprazole;   Drug: Flupentixol and Melitracen Tablets(for dyspepsia symptoms) + Omeprazole;   Drug: Flupentixol and Melitracen Tablets(for depression symptoms) + Omeprazole;   Drug: Flupentixol and Melitracen Tablets(without explanation) + Omeprazole
Outcome Measures: compliance of antidepressant medication;   dyspepsia symptom questionnaire;   psychiatric symptom on Hospital Anxiety and Depression Scale;   quality of life rating;   adverse reaction
9 Unknown  Evaluation of Omeprazole Effect on Glaucoma
Condition: Glaucoma
Interventions: Drug: Omeprazole;   Drug: Placebo
Outcome Measure:
10 Not yet recruiting "Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER-
Condition: Coronary Artery Disease
Interventions: Drug: Pantoprazole,;   Drug: Omeprazole
Outcome Measures: Assessment of platelet reaction units;   Frequency of high platelet reactivity
11 Recruiting Melatonin Associated to Acid Inhibition for Chemoprevention in Barret Esophagus: a Pilot Study
Condition: Barrett's Esophagus
Interventions: Drug: Omeprazole;   Drug: Melatonin
Outcome Measures: Oxidative stress;   Biological markers of diseases progression;   The presence of DNA anomalies (tetraploidy and aneuploidy.
12 Recruiting Rectal and Oral Omeprazole Treatment of Reflux Disease in Infants.
Conditions: Gastroesophageal Reflux;   Esophageal Atresia;   Hernia, Diaphragmatic
Intervention: Drug: Omeprazole suppository
Outcome Measures: Therapeutic efficacy;   Intragastric pH, Pharmacokinetic parameters, PK-PD-relation,;   Pharmacogenetic parameters
13 Recruiting CYP2C19 Genotype Predictor of Gastric Acid Suppression
Condition: Esophagitis
Intervention: Drug: Omeprazole
Outcome Measures: The correlation specific to CYP2C19 genotype with gastric acid suppression by Omeprazole.;   To assess patients gastrointestinal symptoms, in patients with EoE by means of standard validated questionnaires
14 Unknown  Role of CYP2C19 Polymorphism in the Drug Interaction Between Clopidogrel and Omeprazole
Condition: Coronary Artery Disease
Intervention:
Outcome Measures: To test whether concomitant administration of Omeprazole will decrease the platelet inhibitory properties of clopidogrel in subjects with loss of function (LOF) mutation of CYP2C19 (known as *2 and *3).;   To test whether concomitant administration of Omeprazole will decrease the conversion of clopidogrel to its active metabolite in subjects with loss of function (LOF) mutation of CYP2C19 (known as *2 and *3).
15 Not yet recruiting Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSEC
Condition: CDA Type I
Intervention: Drug: Omeprazole
Outcome Measure: evaluate number of adverse effects per patient treated with LOSEC + levels of iron, ferritin,complete blood count and chemistry panel.
16 Unknown  Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, or Famotidine
Conditions: Coronary Heart Disease;   GI Bleeding
Intervention: Drug: PPI Platelet Inhibitory
Outcome Measure: Platelet function as assessed by a CPA system
17 Not yet recruiting Laryngomalacia Study
Condition: Laryngomalacia
Interventions: Drug: Omeprazole;   Drug: Placebo
Outcome Measures: Laryngomalacia Symptom Score;   Caring For a Child with Laryngomalacia Family Impact Questionnaire;   Revised Infant Gastro-Esophageal Reflux Questionnaire;   Reflux Finding Score;   End of treatment 24-hour double-probe pH monitoring;   Weight
18 Unknown  Assessment of Zegerid on Esophageal pH in Patients With Barrett's Esophagus
Conditions: Barrett Esophagus;   Gastroesophageal Reflux
Interventions: Drug: Zegerid (proton pump inhibitor);   Procedure: Bravo pH monitoring
Outcome Measures: Control of esophageal pH;   Control of GERD symptoms
19 Not yet recruiting The Effect of NSAIDs After a Rotator Cuff Repair Surgery.
Condition: Rotator Cuff Tear
Interventions: Procedure: Rotator cuff repair;   Drug: Ibuprofen, Hydrocodone/Acetaminophen, Omeprazole;   Drug: Hydrocodone/Acetaminophen
Outcome Measures: American Shoulder and Elbow Surgeons (ASES) Shoulder Score;   Ultrasound evaluation of retear rate
20 Not yet recruiting Placebo In Chronic Pain
Condition: Chronic Back Pain
Interventions: Drug: Naproxen;   Drug: Placebo;   Drug: Omeprazole
Outcome Measure: VAS pain scale