HAEMOGLOBIN DECREASED and Klonopin

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.

Rank

Status

Study

Recruiting

Comparison Between Lorazepam, Clonazepam and Clonazepam + Fosphenytoin for the Treatment of Out-of-hospital Generalized Status Epilepticus

Conditions:	Status Epilepticus; Epilepsy
Interventions:	Drug: Clonazepam; Drug: Fosphenytoin; Drug: Placebo; Drug: Lorazepam
Outcome Measures:	Percentage of patient with a cessation of seizures and absence of recurrence; Duration between the first cessation and the recurrence of seizures; Percentage of patients having had a second injection of benzodiazepine; Percentage of patients having had an injection of the second line treatment; Percentage of patients having a general anesthesia for refractory status epilepticus; Percentage of patients having had a side effect; Percentage of patients having been mechanically ventilated; Glasgow Coma Scale; Mortality; Length of stay in Intensive Care Unit; Length of stay in hospital

Not yet recruiting

Clobazam Use in Epilepsia Partialis Continua - Pilot Study

Conditions:	Epilepsia Partialis Continua; Kojewnikov's Epilepsy; Epilepsy
Interventions:	Drug: Clobazam; Drug: Clonazepam; Drug: Lorazepam
Outcome Measures:	Time (measured in minutes) to onset of seizure freedom; Reduction of seizure frequency/minute; Mental status preservation off sedating anticonvulsants as measured by the MoCA© scale; Ambulatory function as measured by the Hauser Ambulation Index

Recruiting

Gabapentin Treatment of Benzodiazepine Dependence

Condition:	Benzodiazepine Dependence
Interventions:	Drug: gabapentin; Drug: Placebo
Outcome Measure:	Abstinence from Benzodiazepine use

Unknown ^†

Safety and Tolerability Study of Levetiracetam to Treat Patients With Status Epilepticus

Condition:	Status Epilepticus
Intervention:	Drug: levetiracetam (add-on)
Outcome Measures:	o Uneventful intravenous (iv) administration of study medication; o Toxicity profile on iv administration, including:; § Irritation on injection site; § Hypotension, defined as systolic blood pressure below 90 mm Hg recorded within 24 hours of the dose; § Cardiac arrest (diagnosed clinically) or bradyarrhythmias including heart block, documented on an electrocardiogram; § Respiratory depression, defined as the occurrence of apnea or need for intubation; § Allergic reactions, like skin rash; § Other side-effects; Pharmacokinetic parameters of levetiracetam and clonazepam in patients with SE

Unknown ^†

The Efficacy of Botulinum Toxin in Disabling Multiple Sclerosis (MS) Tremor

Conditions:	Multiple Sclerosis; Tremor
Intervention:	Drug: Botulinum Toxin Type A
Outcome Measures:	A decrease in tremor; The safety profile of Botulinum Toxin in MS patients