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HYPERSENSITIVITY and Simvastatin

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HYPERSENSITIVITY Symptoms and Causes

An allergy is a reaction by your immune system to something that does not bother most other people. People who have allergies often are sensitive to more than one thing. Substances that often cause reactions are

  • Pollen
  • Dust mites
  • Mold spores
  • Pet dander
  • Food
  • Insect stings
  • Medicines

Normally, your immune system fights germs. It is your body's defense system. In most allergic reactions, however, it is responding to a false alarm. Genes and the environment probably both play a role.

Allergies can cause a variety of symptoms such as a runny nose, sneezing, itching, rashes, swelling, or asthma. Allergies can range from minor to severe. Anaphylaxis is a severe reaction that can be life-threatening. Doctors use skin and blood tests to diagnose allergies. Treatments include medicines, allergy shots, and avoiding the substances that cause the reactions.

NIH: National Institute of Allergy and Infectious Diseases

Check out the latest treatments for HYPERSENSITIVITY

HYPERSENSITIVITY treatment research studies

Simvastatin clinical trials, surveys and public health registries


Find Drug Side Effect reports



Simvastatin Side Effects

Rhabdomyolysis (1169)
Myalgia (1039)
Renal Failure Acute (504)
Fatigue (491)
Blood Creatine Phosphokinase Increased (489)
Pain In Extremity (449)
Muscular Weakness (445)
Asthenia (394)
Arthralgia (375)
Muscle Spasms (346)
Pain (328)
Dyspnoea (311)
Dizziness (304)
Nausea (281)
Fall (261)
Diarrhoea (257)
Gait Disturbance (243)
Alanine Aminotransferase Increased (241)
Headache (240)
Myositis (238)
Malaise (187)
Myopathy (180)
Back Pain (166)
Amnesia (163)
Vomiting (160)
Insomnia (157)
Depression (156)
Rash (154)
Aspartate Aminotransferase Increased (152)
Renal Failure (143)
Liver Function Test Abnormal (141)
Abdominal Pain (140)
Chest Pain (134)
Blood Creatinine Increased (133)
Confusional State (130)
Paraesthesia (126)
Hypoaesthesia (126)
Feeling Abnormal (123)
Memory Impairment (122)
Anxiety (117)
Myocardial Infarction (112)
Weight Decreased (111)
Pruritus (107)
Cough (107)
Condition Aggravated (106)
Cerebrovascular Accident (104)
Tendon Rupture (103)
Hepatic Enzyme Increased (101)
Mobility Decreased (98)
Abasia (98)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

I been on simastatin 20gms for 4 yrs. I remember I did had a rash last Aug 09 and it was realy itch. After 2 wks of suffering. I finally made Appt. with my Dr.. They schelule me for the following week. The day I planed t

:(vvery dissy imsoniac light headness.................. =-O

A few months ago my doctor prescribed 40mg simvastatin to take one before bedtime ,and he never told me anything about the side efect of thid drug,I have started feeling some muscle pain and abdomnel paint that was later on after I started taking the

Blurred vision, like I was looking through water around the outside of my eyes, then very dizz, faint but not fainting--this has happened twice, I was shaky and weak after--it was frightening.....

Extreme muscle pain in legs, shoulders, neck and back. already had fibromyalgia and this was worse than any pain had previous to taking simvastatin. I was on it a yr. I had chonic insomnia, chest pain like pneumonia, so tired couldn't hardly move. co

Hair loss

Has anyone taking this medication after a year,expierenced headaches?

Have been on Zocor for almost 10 years with no problems but 6 months ago started getting rash on my left side which seems to be less annoying with good skin lotion. I also take some vitamin pills that have 1000% niacin(for building good HDL) and Niac

I am taking 40 mg of simvaststin and my hair is really falling out bad. it stated this after i've been on the drug for awhile. should i stop taking it to see will my hair stop coming out from the root?

I can certainly sympathize. I began taking 40mg dose of Zocor inNovember of 2009 three days a week. Took for 6 months. Had blood work done in March. Cholesterol level dropped to 206. Doctor

I had a severe reaction to iv cefazolin that was not taken seriously by er nurse and failed to completely subside. i progressively became weaker and ill and believe that it is the cause of the autoimmune disorder and hypersensitivity vasculitis that

Took imigran nasal spray once for serious migraine went to bed the whole of my right side collapsed my right leg does not work i get exqiste hypersensitivity from my knee down my right shoulder has been badly damaged the muscles right side of my back

HYPERSENSITIVITY Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Diagnosis and Physiopathology of Insulin Allergy
Conditions: Diabetes Mellitus, Type 1;   Diabetes Mellitus, Type 2;   Hypersensitivity;   Immediate Hypersensitivity;   Allergy
Intervention: Procedure: Allergy tests
Outcome Measures: Validation of cutaneous insulin tests;   Immunogenetic of patients with IA (Insulin Allergy)
2 Recruiting Evaluating the Effectiveness of a Handbook for Parents of Children Newly Diagnosed With Food Allergy
Condition: Hypersensitivity, Food
Interventions: Other: Food allergy handbook for parents;   Other: Food allergy treatment as usual
Outcome Measures: Change in food allergy-specific quality of life score;   Changes in food allergy knowledge score;   Change in confidence in allergy management skills score;   Change in food allergy outcome expectations score;   Parent satisfaction with study handbook (study intervention)
3 Recruiting Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders
Conditions: Food Hypersensitivity;   Eosinophilia;   Peanut Hypersensitivity;   Eosinophilic Gastroenteritis;   Eosinophilic Esophagitis
Intervention:
Outcome Measure:
4 Recruiting The Diagnosis of Penicillin/Aminopenicillin Allergy in Thailand
Conditions: Penicillin Allergy;   Aminopenicillin Allergy
Intervention:
Outcome Measures: The true prevalence of penicillin/aminopenicillin allergy;   The diagnostic values of currently used skin test reagents and drug-specific IgE measurement
5 Recruiting The Utility of Food-Specific IgE Measured With the IMMULITE 2000 Assay to Predict Symptomatic Food Allergy
Conditions: Peanut Allergy;   Milk Allergy;   Egg Allergy
Intervention: Procedure: Oral food challenge
Outcome Measures: Relationship between food specific IgEs;   Logisitic regression analyses on data
6 Unknown  Food Allergy - Tubes - Adenoids (FATA) Trial
Conditions: Otitis Media With Effusion;   Food Hypersensitivity
Interventions: Other: Food Allergy Diagnosis;   Procedure: Adenoidectomy
Outcome Measure: The number of post-op ROM episodes in each group (1,2,3) will be recorded throughout the study (after the tympanostomy tubes fall out).
7 Recruiting Tree Nuts Allergies: Does a Single Nut Allergy Necessitate the Dietary Eviction of Other Tree Nuts?
Condition: Nut Allergy in Children
Intervention: Other: Oral food challenges to multiple nuts
Outcome Measures: Evaluation of cross reactivity in nut allergic children;   Identify predictive factors of multiple nut allergy;   Quality of life in food allergic children;   Follow up visits to evaluate the uprising of an allergy to a nut regularly ingested
8 Recruiting Basophil Activation Test (BAT) Sensitivity in Child Food Allergy
Conditions: Allergy to Egg;   Allergy to Peanut
Intervention: Biological: Basophil Activation Test
Outcome Measures: Sensitivity of the Basophil Activation Test;   Evaluation of the proportion of child positive to the BAT
9 Recruiting The Natural History of Wheat Hypersensitivity in Thai Children
Conditions: Wheat Allergy;   Child
Intervention: Dietary Supplement: oral wheat challenge
Outcome Measure: The number of participants who outgrow from wheat allergy
10 Recruiting The Effect of Per Oral Immunotherapy in Severe IgE Mediated Egg, Milk, and Nut Allergy in Adults
Condition: Food Allergy
Intervention: Dietary Supplement: Dietary supplement
Outcome Measures: Number of the patients that achieve higher tolerance of allergen with immunotherapy than the measured baseline allergen challenge shows?;   Effect of therapy on lung function.;   Does oral immunotherapy change bronchial hyperreactivity?;   Does the oral immunotherapy have en effect on airway inflammation?
11 Recruiting Allergy Immunotherapy for the Reduction of Asthma
Conditions: Wheezing;   Asthma;   Allergy
Interventions: Biological: Allergen extracts (subcutaneous injections);   Other: Standard of care
Outcome Measures: Combined asthma symptom and asthma medication score;   Prevention of new allergic sensitization as determined by blood and/or skin testing to a panel of 9 common environmental and 9 common food allergens;   Observe Frequency and Phenotype of T regulatory cells in response to immunotherapy
12 Recruiting Peanut Epicutaneous Immunotherapy
Conditions: Peanut Hypersensitivity;   Food Hypersensitivity;   Hypersensitivity;   Hypersensitivity, Immediate
Interventions: Biological: 250 microgram (mcg) DBV712 Viaskin Patch;   Biological: 100 microgram DBV712 Viaskin Patch;   Biological: Placebo Viaskin Patch
Outcome Measures: Percent of subjects desensitized to peanut protein;   Percent of subjects who can successfully consume two different cumulative doses of peanut protein without dose-limiting symptoms;   Percent of desensitized subjects by dose level;   Percent of desensitized subjects as measured by successful 5044 mg peanut protein OFC.;   Number of all adverse events related to therapy;   Number of adverse events in subjects receiving the higher-dose DBV712 Viaskin patch, compared to those in the placebo group;   Number of adverse events in subjects receiving the lower-dose DBV712 Viaskin patch doses compared to the placebo group;   Percentage of subjects who pass an OFC to 5044 mg of peanut protein
13 Recruiting Management of Drug Hypersensitivity in Children
Condition: Drug Hypersensitivity
Intervention:
Outcome Measures: Incidence of suspected drug allergies in a pediatric hospital and the proportion in which these reactions are confirmed to be allergic;   Evaluation of the diagnostic values of the different allergy tests available;   Determination of the role of viruses, HLA typing and gene expression profile both in the acute phase of the reaction and 2 months later
14 Not yet recruiting Caries Prevention Products & Dentinal Hypersensitivity
Condition: Hypersensitivity
Intervention:
Outcome Measure: Change in Dentinal Hypersensitivity
15 Not yet recruiting Health Related Quality of Life in Children With Food Allergy: Comparison to Controls and Other Chronic Diseases
Condition: Children With Food Allergy
Intervention: Other: filling questionnary to quality of life
Outcome Measures: comparison of12 scores of the generic health-related quality of life questionnaire CHQ-CF 87 between children with food allergy and healthy children scores.;   comparaison beetween all questionnary
16 Recruiting Hypoallergenicity To Substitutive Formulas In Children With Cow's Milk Allergy
Condition: Cow's Milk Allergy
Intervention:
Outcome Measure: Number of subjects with cow's milk allergy tolerant substitutive formulas
17 Recruiting FAST-Fish -Food Allergy Specific Treatment for Fish Allergy.
Condition: Fish Allergy
Intervention: Biological: mCyp c 1
Outcome Measures: Safety in the form of number and severity of adverse events;   Specific IgE;   IgG4;   Skin Prick Test
18 Recruiting Molecular Basis of Food Allergy
Conditions: Food Allergy;   Eosinophilic Esophagitis;   Food Protein Induced Enterocolitis
Intervention:
Outcome Measure: T cell Phenotype in Patients with Food Allergy
19 Unknown  Therapeutic Effect of Chinese Herbal Medicine on Food Allergy
Condition: Food Allergy
Intervention: Drug: FAHF-2 (TM)
Outcome Measures: Safety of FAHF-2;   lab studies
20 Not yet recruiting Can Vitamin D Supplementation in Infants Prevent Food Allergy in the First Year of Life? The VITALITY Trial
Condition: Food Allergy
Interventions: Drug: Vitamin D;   Drug: placebo
Outcome Measures: the prevalence and severity of challenge-proven food allergy in study participants with positive skin prick tests (SPT);   prevalence of food sensitisation (positive skin prick) test