| Rank |
Status |
Study |
| 1 |
Recruiting
|
A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal Neuralgia
| Condition: |
Trigeminal Neuralgia |
| Interventions: |
Drug: Amifostine; Procedure: CyberKnife stereotactic radiosurgery |
| Outcome Measures: |
Facial numbness following radiosurgery; Pain relief following radiosurgery |
|
| 2 |
Recruiting
|
Diffusion Tensor Imaging Magnetic Resonance Imaging (DTI MRI) as a Correlate to Pain Relief and Facial Numbness in Patients Following Stereotactic Radiosurgical Rhizotomy for Trigeminal Neuralgia
| Condition: |
Trigeminal Neuralgia |
| Intervention: |
|
| Outcome Measure: |
DTI MRI findings |
|
| 3 |
Unknown †
|
A Clinical Outcomes Study to Measure Reduction in Pain and Numbness During Administration of an Amino Acid Formulation in Subjects Diagnosed With Peripheral Neuropathy
| Conditions: |
Diabetic Neuropathy; Chemotherapy Induced Neuropathy; HIV Neuropathy; Trauma Induced Neuropathy |
| Intervention: |
Drug: Neuron012703 (Medical Food) |
| Outcome Measures: |
VAS; NTSS-6; Routine Blood Panel |
|
| 4 |
Recruiting
|
Stability of the Cochlear Baha BI300/BA400 Implant System Loaded From 1 Week Post-surgery
| Condition: |
Hearing Loss - Conductive |
| Interventions: |
Procedure: One week loading of Bone Anchored Hearing Aid (BAHA); Device: Cochlear Baha BI300/BA400 Implant System |
| Outcome Measures: |
Implant stability; Soft tissue status; Skin overgrowth; Pain around implant; Numbness around implant |
|
| 5 |
Recruiting
|
Clinical Study to Evaluate the Effect of pH on Pain Upon Local Anesthetic Administration.
| Condition: |
Local Anesthetics |
| Interventions: |
Drug: Lidocaine; Drug: normal saline; Drug: alkalinized lidocaine |
| Outcome Measures: |
pain score; time until hypoesthesia; time until anesthesia; pain score upon needle stick. |
|
| 6 |
Recruiting
|
Phase II Study of Minocycline for Reducing Symptom Burden in Colorectal Patients
| Condition: |
Colorectal Cancer |
| Interventions: |
Drug: Minocycline; Drug: Placebo; Behavioral: Questionnaires; Behavioral: Sensory Test |
| Outcome Measure: |
Reduction of Acute Peripheral Neuropathy During Oxaliplatin-Based Chemotherapy |
|
| 7 |
Recruiting
|
Clinical Survey of Oticon Medical Ponto Implants and a Surgical Technique With Tissue Preservation
| Conditions: |
Conductive Hearing Loss; Mixed Hearing Loss; Single Sided Deafness |
| Intervention: |
|
| Outcome Measures: |
Numbness around implant, specifically mean Total sensibility; Length of surgery; Sum of number of unplanned visits, revision surgeries, medications related to implant, and other treatments requiring medical staff per patient; Mild/Adverse skin reaction; Skin condition according to Holgers; Postoperative complications; Proportion of patients with complete wound healing at first surgical visit; Glasgow Benefit Inventory (GBI) scores; Glasgow Health Status Inventory (GHSI) scores; Abbreviated profile of hearing aid benefit (APHAB) scores; Mean hours of use of the sound processor; Bone conduction (BC) in-situ audiometric thresholds; Bone conduction (BC) audiometric threshold; Mean total sensibility around implant; Implant stability quotient (ISQ); Time to implant loss; Patient and Observer scar assessment score |
|
| 8 |
Recruiting
|
Safety of Spinal Anesthesia in Patients With Tibial Shaft Fracture
| Condition: |
Tibial Fracture |
| Interventions: |
Procedure: General anesthesia; Procedure: Spinal anesthesia |
| Outcome Measures: |
Compartment pressure; INVOS values after surgery |
|
| 9 |
Unknown †
|
Small-fiber Neuropathy in Chronic Kidney Disease
| Conditions: |
Small-Fiber Neuropathy; Chronic Kidney Disease |
| Intervention: |
Other: Skin biopsy |
| Outcome Measures: |
The pathology of skin biopsy; Intraepidermal fiber density; Autonomic function; Function of small-fiber sensory nerve |
|
| 10 |
Unknown †
|
A Study of Patient Reported Outcomes After Stereotactic Radiosurgical Rhizotomy for Trigeminal Neuralgia
| Condition: |
Trigeminal Neuralgia |
| Intervention: |
|
| Outcome Measure: |
Patient satisfaction following CyberKnife radiosurgery |
|
| 11 |
Recruiting
|
Effectiveness Study of Hydrotherapy Against Pain and Other Symptoms in Diabetes-induced LEAD
| Conditions: |
Diabetes; Lower Extremity Arterial Disease |
| Intervention: |
Other: hydrotherapy |
| Outcome Measures: |
Change from the intensity of numbness and cold feeling at 4 weeks. Change from the improvement of the pain index at 4 weeks.; Change from ankle-brachial index at 4 weeks |
|
| 12 |
Recruiting
|
Neuroprotection by Tocotrienols in Type 1 and Type 2 Diabetes Mellitus
| Conditions: |
Diabetic Neuropathy; Cognitive Impairment |
| Interventions: |
Dietary Supplement: Tocotrienol; Dietary Supplement: Placebo |
| Outcome Measures: |
Total Symptoms Score (TSS) (pain, paresthesia, burning, and numbness)of patients with diabetes type 1 and 2 neuropathy.; Neuropathy Impairment Score (NIS) of patients with diabetes type 1 and 2 neuropathy |
|
| 13 |
Unknown †
|
Effect of Intraoperative Infiltration With Bupivacain on the Development of Chronic Pain After Inguinal Hernia Repair
| Condition: |
Chronic Pain |
| Interventions: |
Procedure: Infiltration with Saline; Procedure: Infiltration with Bupivacaine |
| Outcome Measures: |
occurrence of chronic pain; Level of Pain:Pain Matcher®,VAS;Areas of hyperalgesia,hypaesthesia Hospitalization:Length of stay (days) ASA-Classification Beginning of mobilisation (days) Return to work or normal activity (days and %) Quality of life (SF36) |
|
| 14 |
Recruiting
|
RFD Versus Cervical Medial Branch Blocks in Chronic Degenerative Neck Pain
| Conditions: |
Facet Joint Arthritis; Pain; Radiofrequency Denervation |
| Interventions: |
Procedure: Radio Frequency Denervation; Procedure: Local Anesthesia |
| Outcome Measures: |
Mean pain intensity measured on a 11-point Numeric Rating Scale (NRS).; Patient Global Impression of Change according to a 7-point Likert scale (PGIC).; Changes in use of pain medication according to the Medication Quantification Scale (MQS).; Changes in the Neck Disability Index scale (NDI).; Changes in quality of life and differences between groups by means of RAND 36.; Improvement in functionality measured by the Patient Specific Functional Scale.; Change in physical/neurological examination parameters.; Change in employment status. |
|
| 15 |
Unknown †
|
Thoracic Manipulation in Patients With Cervical Radiculopathy
| Condition: |
Cervical Radiculopathy |
| Interventions: |
Procedure: Thrust Manipulation - Thoracic Spine; Procedure: Sham Manipulation |
| Outcome Measures: |
Global Rating of Change; Numeric Pain Rating Scale (Neck & Upper Extremity); Neck Disability Index; Cervical Range of Motion; Deep Neck Flexor Endurance; Numbness and Tingling Scale |
|
| 16 |
Not yet recruiting
|
Study of TENS in Reducing Symptoms of Peripheral Neuropathy Induced by Chemotherapy
| Conditions: |
Peripheral Neuropathy; Pain; Paresthesia; Neuritis |
| Interventions: |
Device: active TENS; Device: placebo TENS |
| Outcome Measures: |
Evaluate the effects of TENS in the reduction of symptoms related to peripheral neuropathy due to chemotherapy treatment of a high and moderate neurotoxic potential in cancer patients.; Evaluate the therapeutic response of TENS in symptoms of paresthesia; Evaluate the therapeutic response of TENS in activities of the daily lives of patients.; Evaluate the therapeutic response of TENS in symptoms of neuropathic pain.; Evaluate the factors associated with better treatment response in paresthesia, in pain and activities of daily living. |
|
| 17 |
Unknown †
|
Trial to Evaluate Erectile Function, Fertility and Sperm Count in Male Cyclists Compared to Age Matched Controls
| Conditions: |
Erectile Dysfunction; Azoospermia |
| Intervention: |
|
| Outcome Measure: |
|
|
| 18 |
Not yet recruiting
|
A Pilot Study of Acupuncture for Chemotherapy-induced Peripheral Neuropathy in Breast Cancer Patients
| Conditions: |
Taxane-induced Peripheral Neuropathy; Chemotherapy-induced Peripheral Neuropathy (CIPN); Early-Stage Breast Carcinoma; Stage I Breast Cancer; Stage II Breast Cancer; Stage III Breast Cancer |
| Interventions: |
Procedure: Immediate Acupuncture Group; Procedure: Delayed Acupuncture Group |
| Outcome Measures: |
Response Rate from Baseline in PNQ Score; Changes in FACT/NTX subscale baseline to 8 weeks; Changes in EORTC-QLQ-CIPN20 subscale Baseline, 8 Weeks |
|
| 19 |
Recruiting
|
Acupuncture to Prevent Chemotherapy Dose Reduction Due to Chemotherapy-induced Peripheral Neuropathy in Breast and Colorectal Cancer Patients (GCC1232)
| Conditions: |
Breast Cancer; Colorectal Cancer |
| Interventions: |
Device: Acupuncture using Seirin® needles; Device: Sham Acupuncture using Park Sham placebo acupuncture device |
| Outcome Measures: |
Proportion of colorectal and breast cancer patients in each arm who require dose reduction or discontinuation due to chemotherapy-induced peripheral neuropathy.; Chemotherapy cumulative relative dose intensity; Level of neurotoxicity as assessed by the Functional Assessment of Cancer Therapy/ Gynecologic Oncology Group-Neurotoxicity (FACT/GOG-Ntx) questionnaire; Neuropathic pain as assessed by Neuropathy Pain Scale (NPS) questionnaire; Level of nerve conduction; Serum concentrations of nerve growth factor and other neurotrophic factors |
|
| 20 |
Unknown †
|
The Evaluation of Safety and Efficacy of JWHGWT on Diabetic Neuropathy
| Condition: |
Diabetic Neuropathy |
| Interventions: |
Drug: placebo; Drug: JWHGWT |
| Outcome Measures: |
Short-form (sf)- McGill pain questionnaire (SF-MPQ); Nerve conduction study |
|
