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HYPOGLYCAEMIA and Prednisone

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HYPOGLYCAEMIA Symptoms and Causes

Hypoglycemia means low blood glucose, or blood sugar. Your body needs glucose to have enough energy. After you eat, your blood absorbs glucose. If you eat more sugar than your body needs, your muscles, and liver store the extra. When your blood sugar begins to fall, a hormone tells your liver to release glucose.

In most people, this raises blood sugar. If it doesn't, you have hypoglycemia, and your blood sugar can be dangerously low. Signs include

  • Hunger
  • Shakiness
  • Dizziness
  • Confusion
  • Difficulty speaking
  • Feeling anxious or weak

In people with diabetes, hypoglycemia is often a side effect of diabetes medicines. Eating or drinking something with carbohydrates can help. If it happens often, your health care provider may need to change your treatment plan.

You can also have low blood sugar without having diabetes. Causes include certain medicines or diseases, hormone or enzyme deficiencies, and tumors. Laboratory tests can help find the cause. The kind of treatment depends on why you have low blood sugar.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Check out the latest treatments for HYPOGLYCAEMIA

HYPOGLYCAEMIA treatment research studies

Prednisone clinical trials, surveys and public health registries


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Prednisone Side Effects

Dyspnoea (309)
Pyrexia (283)
Nausea (273)
Pain (263)
Diarrhoea (255)
Arthralgia (247)
Fatigue (246)
Headache (234)
Pneumonia (231)
Pain In Extremity (210)
Asthenia (210)
Vomiting (205)
Dizziness (201)
Oedema Peripheral (198)
Weight Increased (187)
Weight Decreased (175)
Abdominal Pain (172)
Back Pain (169)
Condition Aggravated (161)
Anaemia (156)
Crohn's Disease (113)
Sepsis (110)
Osteonecrosis (105)
Dehydration (104)
Malaise (104)
Fall (101)
Insomnia (100)
Death (100)
Injection Site Pain (100)
Chest Pain (97)
Cough (96)
Confusional State (96)
Diabetes Mellitus (91)
Rash (89)
Blood Glucose Increased (88)
Anxiety (88)
Pulmonary Embolism (88)
Rheumatoid Arthritis (85)
Pruritus (83)
Hypertension (82)
Hypotension (80)
Depression (80)
Febrile Neutropenia (79)
Erythema (78)
Renal Failure (77)
Neutropenia (74)
Deep Vein Thrombosis (73)
Renal Failure Acute (71)
Hyperglycaemia (69)
Muscular Weakness (69)

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Recent Reviews

>:o :'(

3 weeks after i had been given 120m of predisone in a 24 hour period,i started getting dizzy spells severe enough that initially i blacked out while driving,needless to say i havent been driving my car,but i still am experiencing very bad dizzy spell

66 year old male. Good to excellent health. Non smoker, non drinker. Slowly deteriorated till all joints were swollen and eventually I became 99% immobile. Diagnosis? Spotless, Rocky Mountain Spotted Fever. (erlickiosis chaffnesis) Hospitalized, inf

Female patient 39 taking prednisone for asthma. Prednisone 20 mg 4 days on and then one day off/one day onfor8 days. Menstrual type bleeding although not during menstrual period. Severe pelvic cramps and urgency of urination. Swol

I am asthmatic (since I was very little) 36yrs old, took 40mg Prednisone for 8 days - two days later I ovulated and then I started bleeding uncontrollably. Gynae said ovaries failed as blood work tested very low and put me on Duphaston to aid drying

I have taken Prednisone for severe asthma on many occassions (including IV in hospital for 7 days) and suffered severe abdominal pain. Three years ago a gastroscopy revealed I had Duodenal ulcers and Gastritis, most likely caused from the Prednisilo

I take it when i get poison oak or ivy really bad and it takes it away in like 3 days if im fully broken out and i am highly allergic poison ivy, oak and all of that other stuff like that and this stuff helps me tremendously :-D

I take prednione 10mg : 3 tablets once daily for 3 days,then 2 tablets once daily for 3 days,then 1 tabletonce daily for 3 days, then hallf tablets for 4 days. Prednisone give more energy because I have Refractory Anemia with Ringed oblast

I was on a higher dosage - 40mg for 8 days and a few days after I stopped, I started with a 'breakthrough' bleed. Had to have blood tests taken and it showed ovarian failure which DR said could be strongly linked to Prednisone... I am not convinced i

I was recently diagnosed as having rheumatoid arthritis one of the meds prescribed was prednisone one of the side affects that i have noticed is my stomach cramps inthe evening. gonna check to see if I can get a different prescrition

<span style='font-weight: bold;'><a href='http://sideeffects101.com/drug-side-effects/euglucon-hypoglycaemia.htm' rel='nofollow'>hypoglycaemia</a>, little bit of tremor, dosage was just 2.5mg and treated with diovan 80, celebrex 200

HYPOGLYCAEMIA Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting The Effect of Hypoglycaemia on Brain Lactate Accumulation and Cerebral Blood Flow
Conditions: Type 1 Diabetes Mellitus;   Hypoglycemia Unawareness
Intervention: Other: glucose clamp
Outcome Measure: Brain lactate concentration
2 Recruiting Etiology, Assessment and Treatment of Post-gastric Bypass Severe Hypoglycemia
Conditions: Obesity;   Hypoglycemia;   Surgery
Interventions: Dietary Supplement: Oral Glucose tolerance test (OGGT);   Other: Isoglycemic intravenous glucose infusion (IIGI);   Dietary Supplement: Liquid mixed meal;   Drug: Octreotide;   Drug: Synthetic Exendin 9-39
Outcome Measures: Changes in biomedical markers (eg. blood glucose) in response to a liquid meal.;   Continuous Glucose Monitoring as an indicator of post-gastric bypass hypoglycemia
3 Recruiting Outpatient Reduction of Nocturnal Hypoglycemia by Using Predictive Algorithms and Pump Suspension in Children
Condition: Type 1 Diabetes
Intervention: Device: Pump suspension algorithm
Outcome Measures: Comparison of the time spent in hypoglycemia (<70 mg/dl, 3.9 mmol/L) overnight on intervention nights versus control nights, normalized to an 8-hour period.;   Percentage of sensor glucose values 71 to 180 mg/dL (3.9 to 10.0 mmol/L);   Proportion of nights with a sensor glucose value <=70 mg/dL (<=3.9 mmol/L);   Proportion of nights with sensor glucose value <=50 mg/dL (<=2.8 mmol/L);   For the nights when sensor glucose is <=60 mg/dL (<= 3.3 mmol/L), tabulation will be made as to whether blood glucose measured with study blood glucose meter;   Mean home glucose meter morning glucose;   Morning glucose measured with home glucose meter >=250 mg/dL (>=13.9 mmol/L);   Morning blood ketones >1.0 mmol/L;   Morning urine ketones >=small amount;   Mean sensor glucose overnight;   Percentage of sensor glucose values 71 to 180 mg/dL (3.9 to 10.0 mmol/L) overnight;   Area under the curve for sensor glucose <70 mg/dL (3.9 mmol/L), 60 mg/dL (3.3 mmol/L), and 50 mg/dL (2.8 mmol/L);   Area under the curve sensor glucose >180 mg/dL (10.0 mmol/L) and 240 mg/dl (13.3 mmol/L) overnight;   Percent of nights with a CGM value > 250 mg/dL (13.9 mmol/L);   Morning glucose measured with home glucose meter >250 mg/dL (13.9 mmol/L);   Morning ketones >0.6 mmol/L;   Episodes of Diabetic Ketoacidosis (DKA);   Episodes of severe hypoglycemia;   Change in Hemoglobin A1c;   All reported adverse events;   The pump settings will be analyzed for any changes from the baseline visit
4 Recruiting Naltrexone and Hypoglycemia in Type 1 Diabetes
Conditions: Type 1 Diabetes;   Hypoglycemia Unawareness
Intervention: Drug: Naltrexone
Outcome Measures: Cerebral blood flow;   Rates of hypoglycemia
5 Unknown  Lactate and Hypoglycemia
Condition: Hypoglycemia
Interventions: Drug: Lactate;   Drug: Glucose
Outcome Measures: Area under the curve of the glycemia;   Bispectral index variation;   Maximum change in glycemia;   Changes in growth hormone and cortisol;   Need for glucose infusion for persistent hypoglycemia
6 Not yet recruiting Hypoglycemia (Low Blood Sugar) and the Heart
Conditions: Hypoglycemia;   Type 2 Diabetes
Intervention:
Outcome Measures: blood sugar measurement;   Monitor cardiac function
7 Recruiting Bariatric Surgery and Reactive Hypoglycemia
Conditions: Obesity With Complications;   Morbid Obesity;   Reactive Hypoglycemia;   Bariatric Surgery
Interventions: Procedure: Gastric Bypass;   Procedure: Sleeve Gastrectomy
Outcome Measures: incidence reactive hypoglycemia;   insulin resistance
8 Recruiting Study on Lixisenatide and Counterregulation to Hypoglycemia
Condition: Type 2 Diabetes
Intervention: Drug: Lixisenatide
Outcome Measures: Glucagon response to hypoglycemia;   Cortisol response to hypoglycemia;   Catecholamines
9 Recruiting Post-Gastric Bypass Hypoglycemia
Condition: Hyperinsulinemic Hypoglycemia
Interventions: Other: high carbohydrate test meal;   Other: high carbohydrate test meal after pre-treatment with rapid acting aspart insulin;   Other: high fructose , low glucose test meal with carbohydrate and caloric content similar to the control meal
Outcome Measure: The primary study endpoint will be occurrence or not of plasma glucose < 60 mg/dL during the 4 hours after the test meal (binary endpoint).
10 Recruiting Hypoglycemia and Autonomic Nervous System Function
Condition: Hypoglycemia
Interventions: Drug: Eplerenone;   Drug: Placebo
Outcome Measures: Modified Oxford method assessment of baroreflex function;   Muscle sympathetic nerve activity;   Catecholamine response to lower-body negative pressure
11 Recruiting Pramlintide (Symlin) for the Treatment of Hypoglycemia Following Gastric Bypass Surgery
Conditions: Hypoglycemia;   Evidence of Previous Gastric Surgery
Intervention: Drug: Pramlintide
Outcome Measures: Hypoglycemia;   meal hormonal responses
12 Recruiting Hypoglycemia in Prader-Willi Syndrome
Conditions: Prader Willi Syndrome;   Hypoglycemia
Intervention: Other: Infants with Prader-Willi Syndrome
Outcome Measure: Presence of hypoglycemia
13 Recruiting Effect of Naltrexone on Counterregulatory Mechanisms in Hypoglycemia
Condition: Hypoglycemia
Intervention: Drug: Naltrexone
Outcome Measure: Hormone Levels
14 Recruiting Measurement of Glucose Metabolism in Humans Using Magnetic Resonance at 4 Tesla. Substudy: Hypoglycemia Unawareness
Conditions: Type 1 Diabetes;   Hypoglycemia Unawareness
Intervention: Drug: somatostatin
Outcome Measure: Brain glucose concentration as measured by NMR spectroscopy
15 Recruiting Hypoglycemia at Initiation of Pump Therapy in Children With Type 1 Diabetes
Condition: Type 1 Diabetes
Intervention: Other: Observation of hypoglycemias frequency 3 days before and after pump initiation
Outcome Measures: Frequency of hypoglycemias;   Frequency of hyperglycemias
16 Unknown  Safety and Efficacy of a Novel Glucagon Formulation in Type 1 Diabetic Patients Following Insulin-induced Hypoglycemia
Condition: Hypoglycemia
Interventions: Drug: glucagon;   Drug: low dose experimental formulation;   Drug: high dose experimental formulation;   Drug: Medium dose experimental glucagon formulation
Outcome Measures: Percentage of responders;   Number of subjects with adverse events;   Area under the serum concentration versus time curve (AUC) of glucagon;   Peak serum concentration (Cmax)of glucagon;   Peak plasma concentration (Cmax) of glucose;   Area under the plasma concentration versus time curve (AUC) of glucose
17 Recruiting Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus
Condition: Type 1 Diabetes
Interventions: Drug: Dehydroepiandrosterone;   Drug: Placebo
Outcome Measure: Change in level of catecholamines in blood from baseline
18 Recruiting Evaluation of the Effect of Hypoglycemia With PET and a Norepinephrine Transporter Ligand
Condition: Hypoglycemia
Intervention: Other: Norepinephrine Transporter (NET) ligand
Outcome Measures: norepinephrine transporter (NET) ligand concentrations at Baseline;   norepinephrine transporter (NET) ligand concentrations in hyperinsulinemic-hypoglycemic Condition
19 Recruiting The Effects of RT-CGM on Glycemia and QoL in Patients With T1DM and IHA
Conditions: Type 1 Diabetes Mellitus;   Impaired Hypoglycemia Awareness;   Hypoglycemia Unawareness
Intervention: Device: Real-time continuous glucose monitor
Outcome Measures: Time spent in the euglycemic range;   Quality of life;   Glycemia variables;   Hypoglycemic episodes;   Changes in hypoglycemia awareness score
20 Unknown  Do Sulphonylureas Preserve Cortical Function During Hypoglycaemia?
Condition: Type 1 Diabetes Mellitus
Intervention: Drug: Glibenclamide
Outcome Measures: Glucose threshold for development of symptoms and cognitive impairment due to Hypoglycaemia;   Improvement in counter regulatory hormone response to Hypoglycaemia