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HYPOTHYROIDISM and Thyroid

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HYPOTHYROIDISM Symptoms and Causes

Your thyroid is a butterfly-shaped gland in your neck, just above your collarbone. It is one of your endocrine glands, which make hormones. Thyroid hormones control the rate of many activities in your body. These include how fast you burn calories and how fast your heart beats. All of these activities are your body's metabolism. If your thyroid gland is not active enough, it does not make enough thyroid hormone to meet your body's needs. This condition is Hypothyroidism.

Hypothyroidism is more common in women, people with other thyroid problems, and those over 60 years old. Hashimoto's disease, an autoimmune disorder, is the most common cause. Other causes include thyroid nodules, thyroiditis, congenital Hypothyroidism, surgical removal of part or all of the thyroid, radiation treatment of the thyroid, and some medicines.

The symptoms can vary from person to person. They may include

  • Fatigue
  • Weight gain
  • A puffy face
  • Cold intolerance
  • Joint and muscle pain
  • Constipation
  • Dry skin
  • Dry, thinning hair
  • Decreased sweating
  • Heavy or irregular menstrual periods and fertility problems
  • Depression
  • Slowed heart rate

To diagnose Hypothyroidism, your doctor will do a physical exam, look at your symptoms, and do thyroid tests. Treatment is with synthetic thyroid hormone, taken every day.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Check out the latest treatments for HYPOTHYROIDISM

HYPOTHYROIDISM treatment research studies

Thyroid clinical trials, surveys and public health registries


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Thyroid Side Effects

Fatigue (48)
Hypothyroidism (38)
Alopecia (37)
Product Formulation Issue (23)
Headache (23)
Palpitations (22)
Diarrhoea (21)
Feeling Abnormal (21)
Dizziness (21)
Dyspnoea (21)
Product Substitution Issue (20)
Pain (20)
Chest Pain (20)
Asthenia (19)
Weight Increased (19)
Product Quality Issue (18)
Blood Thyroid Stimulating Hormone Increased (17)
Blood Pressure Increased (17)
Heart Rate Increased (17)
Depression (17)
Insomnia (17)
Myalgia (16)
Nausea (15)
Hypertension (15)
Arthralgia (15)
Atrial Fibrillation (15)
Dry Skin (14)
Rash (13)
Tremor (12)
Urticaria (12)
Pain In Extremity (12)
Malaise (12)
Abdominal Pain Upper (11)
Anxiety (11)
Condition Aggravated (11)
Hyperhidrosis (11)
Thyroid Function Test Abnormal (10)
Muscle Spasms (9)
Deep Vein Thrombosis (9)
Flatulence (9)
Hyperthyroidism (9)
Heart Rate Irregular (9)
Confusional State (8)
Blood Thyroid Stimulating Hormone Decreased (8)
Constipation (8)
Vomiting (8)
Weight Decreased (8)
Oedema Peripheral (8)
Extrasystoles (8)
Suicidal Ideation (7)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
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Prednisone (5926)
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Prozac (1954)
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Tamiflu (5585)
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Viagra (5394)
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Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

I have been getting these little blister sores that bust and turn into scap little sores. I have noticed it since about a month or so after found out my thyroid is not working right. Could this be a side effect from the medication

I have only been on it five days, it is better than nothing so far. My own thyroid production took a downfall and I am used to Armour Thyroid which has been my doctor's first choice for years. I was told by my European Doctor that Synthyroid is jus

I'm losing a lot of weight. Was 110 when started on Armour. Lost 15 lbs in one year. Take 90

In the Spring of 2008 I went to my PCP for allergy symptoms, and when he felt my neck glands to make sure that I didn't have something similiar to strept throat, he said that's the biggest Thyrioid I've ever felt, well 2 weeks later the surgeon was r

My husbadn is almost 52, and he has been very ill with a chronic GI condition for the last 12 months. He has been in and out of the hospital and had his gull bladder and appendix removed. They still have no diagnosis for the GI problems. Now last wee

Recently I was put on medication for thyroid. Its a powder compound and they put into capsules for me to take. Its 60mg 1 daily then after one week 1 twice a day. I took it Saturday no side effects. Then Sunday I had no energy and I was so cold I cou

I was diagnosed with hypothyroidism about 2 years ago. I have been prescribed just about every brand of medication for my disorder and have never successfully gotten my symptoms under control, even with some of the more

After becoming very ill, suffering much pain, losing weight and having many sleepless nights i was finally diagnosed with hoshimotos disease, subsequently i have hypothyroidism. I am only talking 50 mg oroxine 3 times a week and 100 mg the other 2 d

Hello ,i got to know i have hypothyroidism for 15 days,reading of TSH>75 . i am adviced by endocrynologist to take ELTROXIN 100mg ,before food early morning. but i am facing some changes in my body after 1 week,such as muscle caught any time anywh

Hi Poona i was diagnosed with Hypothyroidism and was started on 250 mg as my imune system haddecided my pet gland was an enemy. I found the first 4 to 5 months quite strange physically and especially mentally but after t

I am regularly taking Eltroxin for last 15 years due to Hypothyroidism, however for the last 6 months both my of both fingers severely got affected with inflammation and pain especially in the night time. Xray has taken but could not find any conclu

I have been suffering from hypothyroidism for the last 12 years ... 2 years ago my thyroid was completely removed due to cancer... I do suffer from severe headaches all the time ... could this be because of the eltroxin ... I take 150mg eve

I have been taking 25 ug (low dose) of Euthyrox for a month after being diagnosed with subclinical hypothyroidism recently, and whilst I definitely have more energy now and feel more alert during the day, I have found that my skin has been feeling ve

I have Hypothyroidism and have been taking Eltroxin 5mg for a year now. I have noticed that I am quite forgetfull, have problems with focus, fatigue, abdominal discomfort and back pain, irregular menstrual cycles, depression and anxsiety. Isn't Eltro

I have started with Eltroxin only 3 days ago. What bothers me is that my heart beat is high (90 beats/min) and I have chest pain. Isn't any natural way of healing Hypothyroidism?

I started taking meds for hypothyroidism about six months agol. My Dr. started out at a fairly low dose, ande now I am taking El Troxin 0.1mg. In the pastr year I had a largerweitht gain and was told I should lose the weght when I

HYPOTHYROIDISM Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Thyroid Hormone Dose Adjustment in Pregnancy
Conditions: Pregnancy;   Hypothyroidism
Interventions: Drug: Anticipatory dose increase of levothyroxine;   Drug: levothyroxine
Outcome Measures: proportion of patients in each treatment arm euthyroid through gestation;   the proportion of patients in each arm who required, and the gestation week at which, levothyroxine dose adjustments (either increased or decreased) occurred to maintain a euthyroid state;   Determination of the necessary frequency of serum evaluation of TSH during the first half of gestation.
2 Recruiting Study of Optimal Replacement of Thyroxine in the Elderly
Condition: Hypothyroidism
Intervention: Drug: Levothyroxine
Outcome Measures: Participant's acceptability of study design and willingness to enter study;   Participant recruitment rate;   Time to achieve desired TSH levels;   Medication compliance;   The acceptability of three patient completed questionnaires;   Assessment of mobility;   Change in specific cardiovascular risk factors;   Measure of risk of falls
3 Recruiting Study of Dose Adjustment From Levothyroxine to a New Levothyroxine Sodium Test Formulation.
Condition: Hypothyroidism
Intervention: Drug: Levothyroxine sodium new formulation
Outcome Measures: The proportion of patients that do not need a change of dose.;   The magnitude of the change in daily dose needed.;   Proportion of patients that obtained a thyroid stimulating hormone between 0.4-2.5 mU/L;   Change from baseline serum thyroid stimulating hormone (in mIU/L and percentage).
4 Unknown  Thyroxin Treatment in Sub Clinical Hypothyroidism, on the Apnea Hypopnea Index Score, Lipids and Highly Sensitive CRP
Condition: Dyslipidemia
Interventions: Drug: levothyroxine;   Drug: sugar pill
Outcome Measures: Effect of the treatment of subclinical hypothyroidism on the apnea hypopnea index (AHI) score.;   Effect of the treatment of subclinical hypothyroidism on the lipid profile in patient with dyslipidemia and on hs-CRP
5 Recruiting Effects of L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Hypothyroidism
Conditions: Hypothyroidism;   Thyroid Diseases;   Endocrine System Diseases
Intervention: Drug: L-thyroxine
Outcome Measures: Rate of First CVD Events, CVD Mortality and All-cause Mortality;   Change in Serum Lipid Levels;   Change in Thickness of Blood Vessel Wall;   Change in Oxidative Stress and Chronic Inflammatory Factors Associated with Atherosclerosis
6 Recruiting Desiccated Thyroid Extract and Levothyroxine for Hypothyroidism Treatment
Condition: Primary Hypothyroidism.
Interventions: Drug: Levothyroxine;   Drug: Desiccated thyroid extract
Outcome Measures: thyroid-symptom questionnaire;   Wechsler Memory Scale-Version IV (WMS-IV);   Biochemical measures
7 Recruiting Thyroid Hormone Replacement for Subclinical Hypothyroidism
Condition: Subclinical Hypothyroidism
Interventions: Drug: Levothyroxine;   Drug: Placebo
Outcome Measures: Fatal and non-fatal cardiovascular events;   Thyroid-specific quality of life;   Health-related quality of life;   Handgrip strength;   Executive cognitive function;   Total mortality;   Basic Activities of Daily Living;   Extended activities of daily living;   Haemoglobin
8 Recruiting Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
Conditions: Down Syndrome;   Subclinical Hypothyroidism
Intervention: Drug: Levothyroxine
Outcome Measures: Change in non-HDL cholesterol from baseline at 6, 12 and 18 months.;   Change in quality of life from baseline at 6, 12 and 18 months.
9 Recruiting L-Thyroxine Supplementation for Preterm Newborns Less Than 32 Weeks of Gestation With Hypothyroxinemia
Condition: Hypothyroxinemia
Interventions: Drug: L-Thyroxine;   Drug: water
Outcome Measures: Neurodevelopmental outcome;   Morbidity associated with management of newborns < 32 WG with hypothyroxinemia
10 Recruiting Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism
Conditions: Hypothyroidism;   Thyroid Diseases;   Endocrine System Diseases
Intervention: Drug: L-thyroxine
Outcome Measures: change in lipid profile;   change in thickness of blood vessel wall;   change in endothelial function;   change of adipocytokines;   Change of Oxidative Stress and Chronic Inflammatory Factors Related with Atherosclerosis
11 Recruiting Thyroid Study Type 2 Diabetes Mellitus (T2DM)
Conditions: Diabetes;   Hypothyroidism
Intervention: Drug: Euthyrox (levothyroxine)
Outcome Measures: Thyroid hormone-induced change in whole body insulin sensitivity (change in insulin-stimulated glucose disposal) and muscle mitochondrial function;   Thyroid hormone-induced change of lipid content in skeletal muscle and liver and brown adipose tissue activity
12 Recruiting Early Levothyroxine Post Radioactive Iodine
Condition: Graves' Disease
Intervention: Drug: Levothyroxine
Outcome Measures: Prevention of overt hypothyroidism;   Quality of Life
13 Recruiting Antithyroid Drug Treatment of Thyrotoxicosis in Young People
Condition: Paediatric Thyrotoxicosis
Interventions: Procedure: Block and Replace;   Procedure: Dose Titration;   Drug: carbimazole;   Drug: propylthiouracil;   Drug: thyroxine
Outcome Measures: Remission rate as defined by patients who are biochemically euthyroid at the end of the 6 year study period.;   Biochemical control as reflected by blood TSH and thyroxine levels;   The frequency of adverse events on the 2 treatment regimens.
14 Recruiting The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma
Conditions: Thyroid Carcinoma;   Hypothyroidism
Interventions: Other: Black Coffee;   Other: Coffee with Milk;   Other: Black Tea;   Other: Water
Outcome Measures: Change in TSH (thyrotropin-stimulating-hormone) with each beverage type;   Change in TSH with various beverages;   Change in total T4 with each beverage type;   Change in free T4 with each beverage type;   Change in total T3 with each beverage type
15 Not yet recruiting Thyroid Hormones Treatment in Asthma Exacerbation
Condition: Asthma
Interventions: Drug: IV thyroxin;   Drug: Placebo
Outcome Measures: time to normalization of PEF (peak expiratory flow);   Length of stay;   Time to oxygenation;   heart rate;   respiratory rate
16 Recruiting Selenium Supplementation in Pregnancy
Conditions: Pregnancy;   Infertility;   Auto-immune Thyroiditis
Interventions: Dietary Supplement: Selenium;   Other: Sugar Pill Placebo;   Other: Selenium + L-Thyroxine (LT4);   Other: Sugar Pill Placebo + L-Thyroxine (LT4)
Outcome Measures: Changes in TPOab and/or Tgab;   Changes in thyroid volume and echogenicity;   Changes in thyroid hormones (TSH, FT4, FT3);   Evaluation of Maternal risks;   Evaluation of Infant risks;   Changes in of quality of life;   Evaluation of Health Services:;   Changes in the selenium-dependent antioxidant enzyme glutathione peroxidase;   Changes in implantation and pregnancy rates
17 Recruiting The TRUST Study - Depression Substudy
Conditions: Subclinical Hypothyroidism;   Depression
Interventions: Drug: Levothyroxine;   Drug: Placebo
Outcome Measure: Change from baseline in 15-items Geriatric Depression Scale
18 Recruiting Preconceptional Thyroid Screening and Childhood Nerocognitive Function
Condition: Hypothyroidism
Intervention: Procedure: levothyroxine
Outcome Measures: Offspring neurocognitive assessment at 0-3 yrs;   Offspring IQ assessment at 0-3 yrs;   Incidence of neonatal hypothyroid and complications
19 Unknown  The Effect of Thyroid Hormone Levels in Pregnant Women on the Intelligence Quotient (IQ) of Their Children
Conditions: Child Development Disorders;   Pregnancy;   Subclinical Hypothyroidism
Intervention:
Outcome Measure:
20 Recruiting Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children
Condition: Down Syndrome
Intervention: Drug: thyroid hormone and folinic acid
Outcome Measures: GMDS ( Griffiths Mental Development Scale);   BL (Brunet Lezine revised scale)