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INSOMNIA and Lisinopril

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INSOMNIA Symptoms and Causes

What is Insomnia?

Insomnia is a common sleep disorder. If you have it, you may have trouble falling asleep, staying asleep, or both. As a result, you may get too little sleep or have poor-quality sleep. You may not feel refreshed when you wake up.

What are the symptoms of Insomnia?

Symptoms of Insomnia include:

  • Lying awake for a long time before you fall asleep
  • Sleeping for only short periods
  • Being awake for much of the night
  • Feeling as if you haven't slept at all
  • Waking up too early
What are the types of Insomnia?

Insomnia can be acute (short-term) or chronic (ongoing). Acute Insomnia is common. Common causes include stress at work, family pressures, or a traumatic event. It usually lasts for days or weeks.

Chronic Insomnia lasts for a month or longer. Most cases of chronic Insomnia are secondary. This means they are the symptom or side effect of some other problem, such as certain medical conditions, medicines, and other sleep disorders. Substances such as caffeine, tobacco, and alcohol can also be a cause.

Sometimes chronic Insomnia is the primary problem. This means that it is not caused by something else. Its cause is not well understood, but long-lasting stress, emotional upset, travel and shift work can be factors. Primary Insomnia usually lasts more than one month.

Who gets Insomnia?

Insomnia is common. It affects women more often than men. You can get it at any age, but older adults are more likely to have it. You are also at higher risk of Insomnia if you

  • Have a lot of stress
  • Are depressed or have other emotional distress, such as divorce or death of a spouse
  • Have a lower income
  • Work at night or have frequent major shifts in your work hours
  • Travel long distances with time changes
  • Have an inactive lifestyle
  • Are African American; research shows that African Americans take longer to fall asleep, don't sleep as well, and have more sleep-related breathing problems than whites.
What other problems can Insomnia cause?

Insomnia can cause daytime sleepiness and a lack of energy. It also can make you feel anxious, depressed, or irritable. You may have trouble focusing on tasks, paying attention, learning, and remembering. Insomnia also can cause other serious problems. For example, it could make you may feel drowsy while driving. This could cause you get into a car accident.

How is Insomnia diagnosed?

To diagnose Insomnia, your health care provider

  • Takes your medical history
  • Asks for your sleep history. Your provider will ask you for details about your sleep habits.
  • Does a physical exam, to rule out other medical problems that might cause Insomnia
  • May recommend a sleep study. A sleep study measures how well you sleep and how your body responds to sleep problems.
What are the treatments for Insomnia?

Treatments include lifestyle changes, counseling, and medicines:

  • Lifestyle changes, including good sleep habits, often help relieve acute (short-term) Insomnia. These changes might make it easier for you to fall asleep and stay asleep.
  • A type of counseling called cognitive-behavioral therapy (CBT) can help relieve the anxiety linked to chronic (ongoing) Insomnia
  • Several medicines also can help relieve your Insomnia and allow you to re-establish a regular sleep schedule

If your Insomnia is the symptom or side effect of another problem, it's important to treat that problem (if possible).

NIH: National Heart, Lung, and Blood Institute

Check out the latest treatments for INSOMNIA

INSOMNIA treatment research studies

Lisinopril clinical trials, surveys and public health registries


Find Drug Side Effect reports



Lisinopril Side Effects

Angioedema (1911)
Cough (791)
Dyspnoea (519)
Renal Failure Acute (451)
Dizziness (448)
Hyperkalaemia (441)
Swollen Tongue (401)
Hypotension (376)
Fatigue (371)
Nausea (351)
Diarrhoea (317)
Swelling Face (305)
Headache (297)
Lip Swelling (295)
Pain (278)
Blood Pressure Increased (264)
Angioneurotic Oedema (264)
Dysphagia (259)
Asthenia (259)
Completed Suicide (257)
Vomiting (209)
Hypertension (209)
Rash (202)
Pruritus (191)
Fall (163)
Chest Pain (160)
Dehydration (157)
Renal Failure (152)
Syncope (144)
Wheezing (142)
Insomnia (142)
Arthralgia (140)
Malaise (139)
Anxiety (132)
Blood Creatinine Increased (130)
Oedema Peripheral (125)
Toxicity To Various Agents (123)
Feeling Abnormal (119)
Pain In Extremity (117)
Pharyngeal Oedema (117)
Hypersensitivity (113)
Myocardial Infarction (112)
Muscle Spasms (111)
Renal Impairment (110)
Abdominal Pain (109)
Urticaria (109)
Weight Decreased (108)
Back Pain (105)
Paraesthesia (103)
Flushing (103)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

I just started taking lisinopril and am also staying very tired. Dizziness and lightheadness are my biggest problems right now.I am taking this with cardura and zoloft, so it may not count here. But i wanted to share my input and after reading the c

56 yo male 6weeks 10mg per day no niticable side effects

56 yo male. 3 weeks, 10mg. per day. no noticable side effects.

After 2yrs of lisinopril got severe rash on legs,knees and buttocks.hands swollen,lips swollen.all this for 6 months before doc and team took me off lisinopril after extensive testing.now on steroids and antibods to clear up.

Al, you may not have the energy right now, but you really need to find the energy to find a good primary care doctor. Cholesterol levels in the 500 are a huge risk. There are other cholesterol meds out there that work gr

Been on 40 mgs aday for 6 yrs now..i never noticed any problems..also on minoxdil...

Been taking lisinopril for about a year. i now have (maybe) not fully diagnosed,polymyalgia rheumatitus. i'm thinking its from the lisinopril. i have muscle pain in my arms whenever i move them to do something,which is often. i also had pain in my up

Chest/or chest tightening

Dizziness

Do you have access to a blood pressure monitor? I take lisinopril and the pills I take are 10mg. I only take half a pill daily because a whole pill was making me dizzy. Even though I take such a low dose, it keeps my blood pressure in the normal rang

Does anyone else have insomnia problems, with this drug, was fine before taking it, but now having major trouble getting to sleep and staying asleep.

<b>drowsy, insomnia, slight palpitation, nervousness</b>.

<span style='color: #808080;'>Took Diprophos for rheumatoid arthritis. Side effects: insomnia for 2 nights, perspiring during night, redness in face. Increased need to urinate.

<span style='visibility: visible;'><span style='visibility: visible;'>After battling with acute insomnia for about 3 months, my GP prescribed Trimipramine 25mg. This still didn't get me much sleep, so he prescribed Purata 30mg. Better, bu

2 patients given thiocolchicoside reported of muscular stiffness,uneasiness,insomnia,breathlessness and feeling of restlessness, 2 out of 5 patients have reported such experiences after consuming thiocolchicoside.i strongly recommend to withdraw this

2 weeks on it- terrible insomnia and blood pressure went from regular 120/62 to 130/80 Felt as if I were on Prednisone! Stopped drug.

31 years old female, I usesibutramina and feel overwhelmed, palpitations, thirsty all the time, insomnia, bad humor, headaches,an state of euphoria

After having the Clopixol depot I can't get an erection and have insomnia. It's a bad drug and I do not recommend it.

After taking Floxstat, I had nausea and vomiting along and insomnia for that period.

Agression Insomnia

INSOMNIA Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting Bedtime Administration of Amlodipine Versus Lisinopril
Condition: Hypertension
Intervention: Drug: Amlodipine
Outcome Measures: Change in mean sleep-time systolic blood pressure after addition of a bedtime dose of amlodipine versus Lisinopril;   Changes in mean sleep-time diastolic, awake systolic and diastolic blood pressures, including comparison of % achieving target BP;   Impact of individual medications on sleep-time blood pressure drop (dipping status);   Association of baseline renin levels to sleep-time blood pressure drop;   Association of baseline renin levels with response to amlodipine versus Lisinopril;   Association of baseline dipping status with response to amlodipine versus Lisinopril;   Association of age and response to amlodipine versus Lisinopril
2 Recruiting Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab
Conditions: Breast Cancer;   Cardiac Toxicity
Interventions: Drug: Coreg CR®;   Drug: Lisinopril;   Other: placebo
Outcome Measures: Reduction in incidence of trastuzumab-induced cardiotoxicity after 52 weeks of treatment as measured by preservation of LVEF;   Comparison of the LVEF of each treatment group with the placebo arm;   Number of trastuzumab courses completed without interruption;   Quality-of-life changes as assessed by EORTC-QLQ-C30 questionnaire at baseline and at the end of treatment;   Long-term effects of study drugs as assessed at 18 and 24 months (or 6 and 12 months after completion of trastuzumab therapy)
3 Recruiting Lisinopril in Reducing Shortness of Breath Caused by Radiation Therapy in Patients With Lung Cancer
Conditions: Dyspnea;   Non-small Cell Lung Cancer;   Small Cell Lung Cancer
Interventions: Drug: Lisinopril;   Drug: placebo
Outcome Measures: Incidence of grade 3 or higher hypotension, acute kidney injury, allergic reaction, or anaphylaxis, as measured using the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) version 4.0;   Incidence of adverse events as measured using the NCI CTCAE version 4.0;   Quality of life, assessed using lung cancer symptom scale (LCSS), Functional Assessment of Cancer Treatment Lung Cancer (FACT-L), and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Lung Cancer (EORTC-QLQ-LC13);   Incidence of acute respiratory distress (dyspnea), measured using the maximum score, at any time, of the shortness of breath question on the LCSS;   Patient-level symptoms as measured using the Symptom Experience Questionnaire (SEQ)
4 Not yet recruiting CAndesartan vs Lisinopril Effects on the BRain
Conditions: Hypertension;   Mild Cognitive Impairment
Interventions: Drug: Candesartan;   Drug: Lisinopril
Outcome Measures: Executive function (EXAMINER score);   Perfusion and Vasoreactivity (VR);   rs-fMRI
5 Recruiting Clinical Trial of Coenzyme Q10 and Lisinopril in Muscular Dystrophies
Conditions: Duchenne Muscular Dystrophy;   Becker Muscular Dystrophy;   Limb Girdle Muscular Dystrophy
Intervention: Drug: Coenzyme Q10 and Lisinopril
Outcome Measure: myocardial performance index (MPI)
6 Unknown  Paramedic Initiated Lisinopril For Acute Stroke Treatment
Condition: Stroke
Interventions: Drug: Lisinopril;   Drug: Placebo
Outcome Measures: Number of participants enrolled per month;   Proportion fulfilling eligibility criteria;   Proportion attended by research trained paramedic;   Proportion enrolled by research trained paramedic;   Proportion approached but not enrolled;   Additional time spent on scene;   Paramedic compliance;   Hospital staff compliance;   Proportion completing study medication;   Clinical outcome measures;   Adverse events
7 Recruiting Effect of Angiotensin Converting Enzyme Inhibitor, Lisinopril, on Renal Blood Flow and Its Correlation With Proteinuria Reduction in Subjects With Type 2 Diabetes and Kidney Disease
Condition: Type 2 Diabetes
Interventions: Drug: ACEI or ARB;   Drug: Lisinopril
Outcome Measures: Change in renal blood flow (RBF);   Change in Proteinuria
8 Recruiting Genetic Mechanisms in Human Hypertension Renin-angiotensin-aldosterone System (RAAS) Inhibition Study
Condition: Hypertension
Intervention: Drug: Lisinopril, Atenolol
Outcome Measure: One type of blood pressure medication will better treat individuals with certain genetic backgrounds.
9 Recruiting Non-invasive Haemodynamic Assessment in Hypertension
Condition: Arterial Hypertension
Interventions: Drug: Lisinopril;   Drug: Telmisartan;   Drug: Nebivolol;   Drug: Indapamide/hydrochlorothiazide;   Drug: Amlodipine
Outcome Measures: 24-h mean Systolic Blood Pressure (in ABPM);   24-h mean Diastolic Blood Pressure (in ABPM);   daytime mean Systolic Blood Pressure (in ABPM);   daytime mean Diastolic Blood Pressure (in ABPM);   night-time mean Systolic Blood Pressure (in ABPM);   night-time mean Diastolic Blood Pressure (in ABPM);   Systolic Blood Pressure (in OBPM);   Diastolic Blood Pressure (in OBPM);   change from baseline in Systolic Blood Pressure (in OBPM) at 3 months;   change from baseline in Diastolic Blood Pressure (in OBPM) at 3 months;   change from baseline in 24-h Systolic Blood Pressure (in ABPM) at 3 months;   change from baseline in 24-h Diastolic Blood Pressure (in ABPM) at 3 months;   change from baseline in daytime Systolic Blood Pressure (in ABPM) at 3 months;   change from baseline in daytime Diastolic Blood Pressure (in ABPM) at 3 months;   change from baseline in night-time Systolic Blood Pressure (in ABPM) at 3 months;   change from baseline in night-time Diastolic Blood Pressure (in ABPM) at 3 months
10 Recruiting The VALDIATE-D Study
Conditions: Type 2 Diabetes;   Obesity
Interventions: Drug: Calcitriol and Lisinopril;   Drug: Placebo
Outcome Measures: Circulating RAS activity after calcitriol/placebo therapy;   Renal-vascular tissue RAS activity after calcitriol/placebo therapy;   Renal-vascular RAS activity and urien protein after calcitriol/Lisinopril therapy;   Adiponectin levels;   Adipose-tissue RAS measures
11 Not yet recruiting Single Pill to Avert Cardiovascular Events
Condition: Cardiovascular Disease
Interventions: Drug: polipillV1;   Drug: polipillV2;   Drug: usual care
Outcome Measures: compliance with treatment;   changed in blood pressure;   changes in LDL-cholesterol levels;   the main reason for non compliance with treatment;   safety of poli pill measures by laboratorial tests;   combined outcome
12 Recruiting ACE Inhibitors to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Patients: A Pilot Study
Condition: HIV
Interventions: Drug: Lisinopril;   Drug: Placebo
Outcome Measures: Change in HIV RNA (copies/mil CD4);   Change in HIV DNA (copies/mil CD4)
13 Recruiting The Renin-Angiotensin-Aldosterone System and Parathyroid Hormone Control: The RAAS-PARC Study
Condition: Hyperparathyroidism
Interventions: Drug: captopril;   Drug: Lisinopril
Outcome Measures: Parathyroid hormone, before and after, ACE inhibitor administration;   Serum and urinary aldosterone measurements before and after ACE inhibitor use;   Serum calcium before and after ACE inhibitor administration
14 Recruiting Risk Factor Control Before Orthopedic Surgery
Conditions: Osteoarthritis;   Cardiovascular Disease
Interventions: Drug: Metoprolol;   Drug: Lisinopril;   Drug: Atorvastatin;   Behavioral: Lifestyle counseling
Outcome Measures: Composite of cardiovascular events;   Modified composite of cardiovascular events
15 Not yet recruiting Microvascular Disease Exercise Trial
Condition: Coronary Microvascular Disease
Interventions: Behavioral: Exercise Program;   Drug: Medical Therapy
Outcome Measures: Change in MPR on CMR imaging from baseline with intensive medical therapy + supervised exercise versus intensive medical therapy alone.;   Incremental change in MPR with exercise over intensive medical therapy alone in the exercise subgroup;   Identification of reduced MPR (<2.0 ml/g/min) and borderline reduced MPR
16 Not yet recruiting Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery
Condition: Hypertension
Interventions: Drug: Take ACE-I;   Drug: Hold ACE-I
Outcome Measures: Intraoperative Hypotension;   Acute Renal Failure;   Low blood pressure subgroup;   Older age subgroup;   Postoperative Hypertension
17 Recruiting Prognostic Value of the Circadian Pattern of Ambulatory Blood Pressure for Cardiovascular Risk Assessment
Conditions: Essential Hypertension;   Cardiovascular Disease;   Stroke;   Chronic Kidney Disease
Interventions: Drug: Any antihypertensive medication alone or in combination;   Device: Ambulatory blood pressure monitoring
Outcome Measures: To evaluate the impact of circadian time of treatment in cardiovascular, cerebrovascular and renal risk assessment.;   To evaluate the influence of circadian time of treatment in BP control of hypertensive patients.;   To evaluate the prevalence of an altered (non-dipper) BP profile in patients with resistant hypertension as a function of the circadian time of treatment.;   To evaluate the influence of diabetes and circadian time of treatment in the prevalence of an altered (non-dipper) BP profile.;   To evaluate the influence of age and circadian time of treatment in the prevalence of an altered (non-dipper) BP profile.;   To evaluate, for all groups of interest, the prevalence and cardiovascular risk profile of white-coat hypertension.;   To evaluate, for all groups of interest, the prevalence and cardiovascular risk profile of masked hypertension.;   To evaluate, for all previous objectives, potential differences between men and women.;   To evaluate the impact of changes in ambulatory BP in cardiovascular, cerebrovascular and renal risk assessment.
18 Unknown  Effect of ACE-inhibitors on Aortic Stiffness in Elderly Patients With Chronic Kidney Disease
Conditions: Cardiovascular Disease;   Chronic Kidney Disease
Interventions: Drug: angiotensin converting enzyme inhibitor;   Drug: Lisinopril
Outcome Measure: There may be a statistical correlation between eGFR(estimated glomerular function) and PWV (pulse wave velocity) in patients with CKD, the addition of an ACE inhibitor will decrease PWV in all groups, but to a greater extent in patients wil CKD.
19 Recruiting Renal Denervation in Patients After Acute Coronary Syndrome
Conditions: Acute Coronary Syndrome;   Arterial Hypertension
Interventions: Procedure: Renal denervation;   Drug: Metoprolol;   Drug: Lisinopril
Outcome Measures: cardiovascular death;   myocardium infarction;   stroke;   repeat revascularization;   blood pressure changes;   CCS and NYHA;   heart rhythm disturbances;   intima-media index;   IVS thickness;   restenosis;   diastolic disfunction
20 Unknown  Is There a Benefit to Optimize Heart Failure (HF) Treatment in Aged Over 80 Year's Old Patients?
Condition: Heart Failure
Intervention: Drug: - Angiotensin conversing enzyme inhibitors: enalapril, captopril, Lisinopril, ramipril, trandolapril.
Outcome Measures: Change from baseline in quality of life;   Mortality;   Rehospitalisation;   Cardiovascular events;   Cardiac fibrosis;   Quality of life